Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant ....Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant contributions to the new and evolving priority research area of Bioinformation Science (including bioinformatics). Outcomes will include novel techniques for analysis and mining of post-genome data, with applications to developments in Bio-medicine and Bio-agricultureRead moreRead less
The genomic programming of complex organisms. The project will have far-reaching consequences in medicine, agriculture, biotechnology, engineering, information science and associated industries. It will provide a platform for the rationalization of genetic epidemiology and genetic improvement programs, the development of a wide range of new diagnostics and therapies, the development of new core technologies and practical approaches in genetics and genetic diversity, a framework for advanced gen ....The genomic programming of complex organisms. The project will have far-reaching consequences in medicine, agriculture, biotechnology, engineering, information science and associated industries. It will provide a platform for the rationalization of genetic epidemiology and genetic improvement programs, the development of a wide range of new diagnostics and therapies, the development of new core technologies and practical approaches in genetics and genetic diversity, a framework for advanced genetic engineering, the development of new principles and systems for information storage and transmission, and the design of artificial systems capable of self-referential assembly in other environments.Read moreRead less
The Physics of Network Computation. This project combines expertise in nonlinear soliton physics and computational sciences in order to provide new insights into the physics of network computation. Our proposal addresses the mathematics and computer modelling underlying nonconscious problem solving. We develop a new template concept, the meta-mode, which embodies the network structure of knowledge and the linking mechanisms, which underpin human creativity. We establish the optimal connectiv ....The Physics of Network Computation. This project combines expertise in nonlinear soliton physics and computational sciences in order to provide new insights into the physics of network computation. Our proposal addresses the mathematics and computer modelling underlying nonconscious problem solving. We develop a new template concept, the meta-mode, which embodies the network structure of knowledge and the linking mechanisms, which underpin human creativity. We establish the optimal connectivity distributions to preserve distinct pattern classes yet allow model radical shifts in paradigms, and develop algorithms for autonomous connectivity optimisation. We investigate nonlinear process such as solitons and random Boolean networks as realisations of these principles.Read moreRead less