Nettles & toxic toupees: the molecular weaponry of venomous caterpillars. This project aims to investigate the structure, function and evolution of peptide toxins in venoms made by caterpillars in superfamily Zygaenoidea. Caterpillars in this group are covered in spines that inject pain-causing venoms, and this protects them from vertebrate and invertebrate predators. This project will test if peptides in this venom cause pain by pharmacological modulation of mammalian ion channels and signallin ....Nettles & toxic toupees: the molecular weaponry of venomous caterpillars. This project aims to investigate the structure, function and evolution of peptide toxins in venoms made by caterpillars in superfamily Zygaenoidea. Caterpillars in this group are covered in spines that inject pain-causing venoms, and this protects them from vertebrate and invertebrate predators. This project will test if peptides in this venom cause pain by pharmacological modulation of mammalian ion channels and signalling receptors, and if they have insecticidal properties. The first three-dimensional structures of caterpillar venom peptides will also be solved. Genomes of representatives of two different zygaenoid families will be produced, and genomic techniques will be used to elucidate how venom use evolved at the molecular level.Read moreRead less
Sperm competition, sexual conflict, and gamete evolution in mice. The innovative experiments of this project will yield results that are at the forefront of research in evolutionary biology. This project will generate publications in high profile journals, and will foster collaborations between Australian and European researchers, creating a significant international impact and promoting excellence in Australian research. Since European settlement of Australia, sixty percent of the native rodent ....Sperm competition, sexual conflict, and gamete evolution in mice. The innovative experiments of this project will yield results that are at the forefront of research in evolutionary biology. This project will generate publications in high profile journals, and will foster collaborations between Australian and European researchers, creating a significant international impact and promoting excellence in Australian research. Since European settlement of Australia, sixty percent of the native rodent species have become extinct or are threatened with extinction. As there is a significant lack of research on the mating systems of Australian rodents, our investigations on a native mouse will generate information that will be extremely valuable to the national conservation efforts of threatened rodent species.Read moreRead less
Predicting adaptive responses to climate change in Australian native bees. This project aims to understand how insects will adapt to climate change by examining a largely overlooked but economically important group of species: Australian native bees. Native bees are important pollinators of both crops and native plants, but their sensitivity to changes in climate are unknown. Expected outcomes include new knowledge of the resilience of native bees to climate change, and new effective tools for p ....Predicting adaptive responses to climate change in Australian native bees. This project aims to understand how insects will adapt to climate change by examining a largely overlooked but economically important group of species: Australian native bees. Native bees are important pollinators of both crops and native plants, but their sensitivity to changes in climate are unknown. Expected outcomes include new knowledge of the resilience of native bees to climate change, and new effective tools for predicting climate change resilience that can be applied to many species. The intended benefits include increasing our understanding of the potential for native bees to act as future pollinators in Australia’s natural and agro-ecosystems, and guide policy and management decisions to better protect and conserve our bee fauna.Read moreRead less
Multi-trait plasticity in response to a changing climate. This project aims to understand the effect of climate change on natural populations. Phenotypic plasticity (the ability to change phenotype with environment) determines natural populations’ immediate response to environmental change. However, studies of plasticity frequently rely on simplifying assumptions, and understanding the genomic and epigenomic mechanisms underlying plasticity is only just emerging. This project will combine a fine ....Multi-trait plasticity in response to a changing climate. This project aims to understand the effect of climate change on natural populations. Phenotypic plasticity (the ability to change phenotype with environment) determines natural populations’ immediate response to environmental change. However, studies of plasticity frequently rely on simplifying assumptions, and understanding the genomic and epigenomic mechanisms underlying plasticity is only just emerging. This project will combine a fine-scale temperature-manipulation experiment with genomic and multivariate statistical analyses of a native Australian alpine plant. The intended outcome is a comprehensive analysis of whether multi-trait phenotypic plasticity is adaptive; whether it can evolve; and the epigenomic mechanisms that drive it. The project will predict the likely effect of temperature change on alpine plants, and so generate information internationally relevant to the management of populations adapting to climate change and locally relevant to the conservation of Australian montane flora.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101520
Funder
Australian Research Council
Funding Amount
$365,058.00
Summary
Diet, variance and individual variability in life-history. This project aims to provide biologists with novel statistical tools that will shift analytical paradigms. In many species, dietary restrictions increase average lifespan, and affect average rates of growth and reproduction, also known as ‘life history’. The use of recently developed tools has shown that individual variability in life history also appears to increase under dietary restrictions. This project will explore the effects of di ....Diet, variance and individual variability in life-history. This project aims to provide biologists with novel statistical tools that will shift analytical paradigms. In many species, dietary restrictions increase average lifespan, and affect average rates of growth and reproduction, also known as ‘life history’. The use of recently developed tools has shown that individual variability in life history also appears to increase under dietary restrictions. This project will explore the effects of diet composition on variability in life-history traits, and the factors driving this variation. This is expected to improve the prediction of the effects of changing nutritional environments.Read moreRead less
Evolution in action or the demise of iconic Australian flora? The project aims to investigate the evolutionary history and conservation status of a group of closely related Grevillea species, in the light of increasing pressure from landscape modification. This project will incorporate leading methodologies for massively parallel sequencing, pollinator preference and breeding capacity in order to detect the patterns and processes underpinning divergence in widely distributed species. A phylogene ....Evolution in action or the demise of iconic Australian flora? The project aims to investigate the evolutionary history and conservation status of a group of closely related Grevillea species, in the light of increasing pressure from landscape modification. This project will incorporate leading methodologies for massively parallel sequencing, pollinator preference and breeding capacity in order to detect the patterns and processes underpinning divergence in widely distributed species. A phylogenetic framework will provide the evolutionary relationships among taxa. This project is expected to inform requirements for long-term species persistence and, for threatened species within the group, guide the decision making of biodiversity managers as to what actions are required and where best to invest limited funds.Read moreRead less
Evolving rates: foundations for the next generation of molecular clocks. This project aims to investigate the causes and consequences of variation in rate of DNA sequence evolution across three kingdoms of life. Dates estimated from DNA sequences have a wide range of applications, including evolutionary biology, conservation prioritisation and epidemiology. These methods rely on accurate rate estimates, but current models lack information about the biological drivers of rates of genomic change. ....Evolving rates: foundations for the next generation of molecular clocks. This project aims to investigate the causes and consequences of variation in rate of DNA sequence evolution across three kingdoms of life. Dates estimated from DNA sequences have a wide range of applications, including evolutionary biology, conservation prioritisation and epidemiology. These methods rely on accurate rate estimates, but current models lack information about the biological drivers of rates of genomic change. This project will test reliability of current methods, identify potentially misleading estimates of disease origin or conservation priorities, and develop new approaches with empirically-informed models of rate change.Read moreRead less
Are evolutionary refugia traps for endemic species? This project aims to determine whether species that have small geographic ranges and which live in historically stable refugia have evolved narrow climatic tolerances. The project will compare such species with more widespread, related species living in the same areas and combine field- and lab-based estimates of physiological tolerances with genomic estimates of population history and diversity. The expected outcome is to test the prediction f ....Are evolutionary refugia traps for endemic species? This project aims to determine whether species that have small geographic ranges and which live in historically stable refugia have evolved narrow climatic tolerances. The project will compare such species with more widespread, related species living in the same areas and combine field- and lab-based estimates of physiological tolerances with genomic estimates of population history and diversity. The expected outcome is to test the prediction from evolutionary theory that small-range, refugial species are intrinsically more sensitive to climatic change. The project expects to provide improved guidance for ecological management of biodiversity hotspots.Read moreRead less
Artificial light at night as a driver of evolutionary change. This project aims to investigate whether artificial light at night drives evolutionary change using a combination of field observations, laboratory experiments and advanced genetic techniques. This multi-disciplinary study expects to provide a significant advance in understanding of the impact of light at night for animals and will enhance our capacity to predict the outcome of future urban expansions for all species. The outcomes wil ....Artificial light at night as a driver of evolutionary change. This project aims to investigate whether artificial light at night drives evolutionary change using a combination of field observations, laboratory experiments and advanced genetic techniques. This multi-disciplinary study expects to provide a significant advance in understanding of the impact of light at night for animals and will enhance our capacity to predict the outcome of future urban expansions for all species. The outcomes will have broad implications for estimating the future biodiversity and health of our urban areas and will benefit both globally and within Australia by providing much needed data regarding the likely resilience of species currently residing in our major cities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100115
Funder
Australian Research Council
Funding Amount
$180,000.00
Summary
Confocal microscope for high-resolution microtopographic analysis of surfaces in historical, forensic and polymer sciences. High-resolution analyses of microscopic patterns on surfaces using confocal microscopy can provide vital clues into the nature of ancient diets and environments, adaptive evolution, weapons used in crimes, and properties of polymers. This instrument will heighten Australia’s capacity for world-leading research in areas of major national importance.