MicroRNA Expression And Genome-Wide Epigenetic Analysis Of Paediatric Acute Lymphoblastic Leukaemia (ALL)
Funder
National Health and Medical Research Council
Funding Amount
$71,765.00
Summary
Acute Lymphoblastic Leukaemia (ALL) is one form of childhood leukaemia, the causes for which are unknown. Evidence suggests genome changes are associated with ALL, specifically epigenetic changes such as DNA methylation and microRNA dysregulation. We aim to investigate these changes associated with childhood ALL. We believe this will refine the current diagnostic measures, more accurately predict patients� treatment response, and detect the minimal residual disease during and after treatment.