Microchip Impedance Biosensor for Biomedical Diagnostics. This research proposal uses an innovative engineering approach based on novel nanomaterials with the aim of developing a new and generic biosensing technology with the potential to be widely applied in many areas including medical diagnostics, environmental control, industry and biosecurity. The outcomes from this project will benefit Australia by contributing through the development of novel materials, new technologies and new devices. ....Microchip Impedance Biosensor for Biomedical Diagnostics. This research proposal uses an innovative engineering approach based on novel nanomaterials with the aim of developing a new and generic biosensing technology with the potential to be widely applied in many areas including medical diagnostics, environmental control, industry and biosecurity. The outcomes from this project will benefit Australia by contributing through the development of novel materials, new technologies and new devices. The development of technological innovations based on fabricated nanomaterials, will also enhance capacity in frontier technology such as nanotechnology, and build Australia’s strength in using new biosensing technologies.Read moreRead less
New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordi ....New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordinary people to gain knowledge about the concentrations of molecular compounds in their environments and in themselves. This will stimulate economic and social benefits related to environmental testing and early disease diagnosis and generate new commercial opportunities for the Australian biotechnology industry.Read moreRead less
Development of redox-mediated microbial assays for the rapid characterisation and assessment of wastewater, wastewater treatment processes and recycled water. With SE Qld on Level 5 water restrictions the need to reduce our demand on drinking water by increasing our reliance on recycled water is now urgent. To achieve this we need to ensure that the quality of our recycled wastewater is of a suitable and reliable standard. This project will assist the water industry in this endeavour by the de ....Development of redox-mediated microbial assays for the rapid characterisation and assessment of wastewater, wastewater treatment processes and recycled water. With SE Qld on Level 5 water restrictions the need to reduce our demand on drinking water by increasing our reliance on recycled water is now urgent. To achieve this we need to ensure that the quality of our recycled wastewater is of a suitable and reliable standard. This project will assist the water industry in this endeavour by the developing monitoring techniques that can rapidly characterise and assess the effectiveness of wastewater treatment processes and the quality of the water derived from them. These methods will provide early warnings of potential 'upsets' in treatment plants that would otherwise result in poor quality effluents that would need to be discharged as waste rather than be recycled.Read moreRead less
Calibration Free Coulometric Sensors Based on Polymeric Thin Layer Films. The world faces enormous environmental and clinical challenges that require accurate data from remote deployable and disposable sensors. Many key parameters important to global warming (carbon dioxide cycle) and clinical diagnostics (blood electrolytes) may be assessed with a polymeric membrane sensing technology, but the measurement principle is not sufficiently robust for remote sensing applications. This research will m ....Calibration Free Coulometric Sensors Based on Polymeric Thin Layer Films. The world faces enormous environmental and clinical challenges that require accurate data from remote deployable and disposable sensors. Many key parameters important to global warming (carbon dioxide cycle) and clinical diagnostics (blood electrolytes) may be assessed with a polymeric membrane sensing technology, but the measurement principle is not sufficiently robust for remote sensing applications. This research will make this possible by adapting calibration free measurement principles (coulometry, or charge counting) to this class of sensors, where a thin layer of sample solution will be depleted by instrumental control. This forms the scientific basis for successfully tackling the measurement challenges of the future.Read moreRead less
Novel nanosensors for monitoring of water filtration membrane integrity. Novel nanosensors for monitoring of water filtration membrane integrity. This project aims to develop arrays of electrochemical biosensors based on nanostructured silicon for real-time monitoring of water filtration membrane integrity. Real-time monitoring of membrane performance, based on removing virus-sized particles, is a priority for the water industry to maximise asset life and meet increased demand for safe and high- ....Novel nanosensors for monitoring of water filtration membrane integrity. Novel nanosensors for monitoring of water filtration membrane integrity. This project aims to develop arrays of electrochemical biosensors based on nanostructured silicon for real-time monitoring of water filtration membrane integrity. Real-time monitoring of membrane performance, based on removing virus-sized particles, is a priority for the water industry to maximise asset life and meet increased demand for safe and high-quality water. Materials scientists, electrochemists, and specialists in water management and reuse aim to harness advances in nanostructured transducers and electrochemical protocols to develop online performance-monitoring technology. This project is expected to improve water treatment processes, removing viruses and reducing the risks and uncertainties of water recycling.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120102503
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Circulating tumor cell isolation and detection: an integrated microfluidic capture device based on alternating current (AC) electrohydrodynamics. The detection of circulating tumor cells in clinical samples plays a critical role in cancer diagnosis and management. This project aims to develop microfluidic technology by incorporating AC electric field-induced vortices with three-dimensional microstructured electrodes that will advance our ability to analyse rare cells and proteins in clinical sam ....Circulating tumor cell isolation and detection: an integrated microfluidic capture device based on alternating current (AC) electrohydrodynamics. The detection of circulating tumor cells in clinical samples plays a critical role in cancer diagnosis and management. This project aims to develop microfluidic technology by incorporating AC electric field-induced vortices with three-dimensional microstructured electrodes that will advance our ability to analyse rare cells and proteins in clinical samples.Read moreRead less
Development of a Novel Photoelectrochemical Method for Ultra-sensitive and Selective Determination of Organic Pollutants. Rapidly deteriorating environmental conditions have caused worldwide fresh water shortage problems. For Australia, this is an urgent issue due to our limited fresh water resources. Globally, all levels of governments and legislative authorities have attempted to adopt stricter environmental legislation and better water resource management practice to address these urgent prob ....Development of a Novel Photoelectrochemical Method for Ultra-sensitive and Selective Determination of Organic Pollutants. Rapidly deteriorating environmental conditions have caused worldwide fresh water shortage problems. For Australia, this is an urgent issue due to our limited fresh water resources. Globally, all levels of governments and legislative authorities have attempted to adopt stricter environmental legislation and better water resource management practice to address these urgent problems. However, these priorities cannot be achieved until large scale and accurate environmental data are available. The success of the project would result in a new environmental monitoring system capable of online, real-time monitoring of environmental water quality, which will directly benefit water resource management practice in Australia. Read moreRead less