Make up your mind! - Dissociating the roles of orbitofrontal cortex and striatum in human decision making. How we make everyday decisions is a crucial behaviour of humans but the underlying processes in the brain are still poorly understood. This project will investigate what the roles of specific brain regions are in human decision making, which enable us to gain a better understanding of how these brain structures contribute to our decisions.
I like you and I just can't help it: Explaining automatic affective responses. Our automatic affective responses are crucial in determining how we behave particularly in situations where there is little conscious deliberation. These automatic responses have been implicated in dysfunctional behaviours such as unhealthy food choices and racial bias. However very little research has investigated the psychological processes responsible for the formation of these automatic affective responses. The ai ....I like you and I just can't help it: Explaining automatic affective responses. Our automatic affective responses are crucial in determining how we behave particularly in situations where there is little conscious deliberation. These automatic responses have been implicated in dysfunctional behaviours such as unhealthy food choices and racial bias. However very little research has investigated the psychological processes responsible for the formation of these automatic affective responses. The aim of this project is to investigate the role of conditioning and cognitive processes in the formation and expression of automatic affective responses. This will allow for the development of novel interventions targeting automatic responses which contribute to dysfunctional behaviour. Read moreRead less
Predicting Behaviour from Brain Representations. This project aims to advance our understanding of how perceptual information is represented in the human brain and to link the structure of perceptual brain representations to human behaviour. The project plans to use complementary methods for recording brain activity (human neuroimaging and primate single-cell neurophysiology) and cutting-edge analytic techniques to generate a predictive model of behaviour based on the structure of perceptual bra ....Predicting Behaviour from Brain Representations. This project aims to advance our understanding of how perceptual information is represented in the human brain and to link the structure of perceptual brain representations to human behaviour. The project plans to use complementary methods for recording brain activity (human neuroimaging and primate single-cell neurophysiology) and cutting-edge analytic techniques to generate a predictive model of behaviour based on the structure of perceptual brain representations. It is anticipated that the results will significantly advance the field of cognitive neuroscience by providing a novel empirical framework for understanding how brain representations are predictive of behaviour.Read moreRead less
Neuronal and behavioural correlates of sensory adaptation. Sensory systems adapt to the statistics of their environment, and the consequences of this adaptation are evident in neuronal activity and in animal’s behaviour. This project will employ a novel paradigm to characterise how adaptation changes the response properties of individual sensory neurons to improve efficiency of information transmission.
Cognitive flexibility from adolescence to senescence: variability associated with cognitive strategy and brain connectivity. Healthy living in our complex and unpredictable world depends on the ability to flexibly adjust to novelty and change. This project will study how cognitive flexibility changes from adolescence to senescence, identify the brain networks that mediate this change and explore the implications for successful adaptation in everyday life.
Improving performance in high risk environments using guided distraction and iconic cues. This project tests a novel strategy to assist operators in high-risk automated environments, in order to maintain their performance in low workload situations. Using guided distraction, this project will be able to show improvements in attention to critical tasks and in overall system performance, thereby reducing the potential for error.
PET imaging of learning-related plasticity in awake behaving rats. The objective of the project is to combine an investigation of basic learning paradigms with functional Positron emission tomography (PET) imaging in rats in order to answer critical questions about the neurobiological basis of learning and decision-making in the brain. MicroPET technology provides PET images without the confounds induced by anaesthesia. Using this technology, the project intends to observe whole-brain changes in ....PET imaging of learning-related plasticity in awake behaving rats. The objective of the project is to combine an investigation of basic learning paradigms with functional Positron emission tomography (PET) imaging in rats in order to answer critical questions about the neurobiological basis of learning and decision-making in the brain. MicroPET technology provides PET images without the confounds induced by anaesthesia. Using this technology, the project intends to observe whole-brain changes in dopamine neurotransmission in awake, behaving rats while they learn to predict motivationally relevant outcomes based on environmental cues and on their own actions (ie during Pavlovian and instrumental conditioning, respectively). The outcomes of this research may improve our understanding of the neural changes responsible for debilitating disorders of the brain and mind.Read moreRead less
Hippocampal regulation of goal-directed decision-making. The hippocampus is a part of the brain that is central to learning and memory yet little is known about its role in decision-making. It is the aim of this application to provide the first detailed, causal evidence of hippocampal regulation of decision-making. This is significant because many mental health disorders and dementias that involve decision-making deficits are characterised by hippocampal dysfunction, but any direct link between ....Hippocampal regulation of goal-directed decision-making. The hippocampus is a part of the brain that is central to learning and memory yet little is known about its role in decision-making. It is the aim of this application to provide the first detailed, causal evidence of hippocampal regulation of decision-making. This is significant because many mental health disorders and dementias that involve decision-making deficits are characterised by hippocampal dysfunction, but any direct link between these factors is unknown. The outcomes of the current grant will provide the first evidence of that link, thus providing deeper understanding of the neurophysiological mechanisms of these disorders, which could eventuate in the creation of more beneficial treatments. Read moreRead less
Towards an integrated model of reasoning and reasoning development. This project aims to identify the core cognitive processes that underlie different forms of reasoning and how they develop. The project intends to use a signal detection framework to derive detailed computational models of reasoning which can then be tested through Bayesian computational modelling as well as the first systematic investigation of developmental change in reasoning processes. Expected outcomes include a more princi ....Towards an integrated model of reasoning and reasoning development. This project aims to identify the core cognitive processes that underlie different forms of reasoning and how they develop. The project intends to use a signal detection framework to derive detailed computational models of reasoning which can then be tested through Bayesian computational modelling as well as the first systematic investigation of developmental change in reasoning processes. Expected outcomes include a more principled and comprehensive computational model of reasoning in both adults and children. The project should provide significant benefits by helping to resolve long-standing debates about how humans reason complex arguments relevant to everyday lives and guide development of more effective methods for teaching reasoning.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150100667
Funder
Australian Research Council
Funding Amount
$328,000.00
Summary
How “known unknowns” become known: How do people encode unpredictability? As Donald Rumsfeld noted, there are 'known unknowns’. That is to say, people are seemingly capable of learning that some things cannot be reliably predicted. This learning underpins decisions from the trivial (whether to pack a jacket) to the life-defining (whom to marry). An aberrant form of this learning may also underlie mental health disorders. Yet the mechanisms of such learning have been largely overlooked by cogniti ....How “known unknowns” become known: How do people encode unpredictability? As Donald Rumsfeld noted, there are 'known unknowns’. That is to say, people are seemingly capable of learning that some things cannot be reliably predicted. This learning underpins decisions from the trivial (whether to pack a jacket) to the life-defining (whom to marry). An aberrant form of this learning may also underlie mental health disorders. Yet the mechanisms of such learning have been largely overlooked by cognitive scientists and thus are poorly understood. The project, which is based on significant pilot data, aims to examine when and how people learn about unpredictability, and what the cognitive, memorial, neural and affective consequences of this learning are.Read moreRead less