Optimal management of threatened amphibian metapopulations in urbanising landscapes. This project will enable the identification of optimal management strategies for many species threatened by the loss and fragmentation of their habitat, both in Australia and internationally. Our research will contribute to the recovery of the endangered Growling Grass Frog, and drive the conservation of wetland biodiversity on the fringe of Australia's fastest growing city. Both the methods and specific recomme ....Optimal management of threatened amphibian metapopulations in urbanising landscapes. This project will enable the identification of optimal management strategies for many species threatened by the loss and fragmentation of their habitat, both in Australia and internationally. Our research will contribute to the recovery of the endangered Growling Grass Frog, and drive the conservation of wetland biodiversity on the fringe of Australia's fastest growing city. Both the methods and specific recommendations for management that we develop will contribute to the goal of an environmentally-sustainable Australia. This project will expand Australia's capacity to solve conservation problems, and will promote biological diversity in urban environments, to the benefit of their human inhabitants.Read moreRead less
Genes to phenotype: Exploiting the marsupial model. This research will exploit one of Australia's finest natural resources, its marsupial fauna. The features of marsupial reproduction and development provide a unique opportunity to answer fundamental biological questions. This research will show how the minor differences in key developmental genes that have arisen in their 100 million year isolation give rise to the characteristic differences in developmental timing and reproduction between mar ....Genes to phenotype: Exploiting the marsupial model. This research will exploit one of Australia's finest natural resources, its marsupial fauna. The features of marsupial reproduction and development provide a unique opportunity to answer fundamental biological questions. This research will show how the minor differences in key developmental genes that have arisen in their 100 million year isolation give rise to the characteristic differences in developmental timing and reproduction between marsupials and other mammals. The focus on reproduction and development will also provide invaluable knowledge to underpin efforts to conserve our endangered species and to control those that are overabundant.Read moreRead less
Re-uniting marsupials and eutherians by embryonic micromanipulation. The unique responsibility for transmitting life from generation to generation normally depends on the gametes. This project will use new reproductive technologies to investigate the properties of the oocyte in reprogramming somatic cell nuclei, and will use the nuclei of both marsupial and eutherian somatic cells to test this. We will also use both marsupial and eutherian genes to insert into the oocyte to create the first tra ....Re-uniting marsupials and eutherians by embryonic micromanipulation. The unique responsibility for transmitting life from generation to generation normally depends on the gametes. This project will use new reproductive technologies to investigate the properties of the oocyte in reprogramming somatic cell nuclei, and will use the nuclei of both marsupial and eutherian somatic cells to test this. We will also use both marsupial and eutherian genes to insert into the oocyte to create the first transgenic marsupials. We will also investigate the ability of spermatozoa from species of increasing genetic distance to ferttilise marsupial eggs using intracytoplasmic sperm injection (ICSI).Read moreRead less