Discovery Early Career Researcher Award - Grant ID: DE140101375
Funder
Australian Research Council
Funding Amount
$395,220.00
Summary
The forest and the trees: How global brain rhythms facilitate local information processing. One of the greatest challenges in understanding the brain is the enormous range of scales it operates on, from single neurons a few microns across to entire hemispheres on the scale of tens of centimetres. This project will investigate how large-scale brain rhythms influence and facilitate information processing, particularly motor control, among small networks of individual neurons. The research question ....The forest and the trees: How global brain rhythms facilitate local information processing. One of the greatest challenges in understanding the brain is the enormous range of scales it operates on, from single neurons a few microns across to entire hemispheres on the scale of tens of centimetres. This project will investigate how large-scale brain rhythms influence and facilitate information processing, particularly motor control, among small networks of individual neurons. The research questions will be addressed by combining detailed computer simulations with data-driven analyses of empirical human and monkey brain dynamics. The outcomes of this project will provide a richer understanding of how our brains encode and process information, leading to practical benefits such as improved control of artificial limbs.Read moreRead less
High-resolution multiscale modelling of pandemics: COVID-19 and beyond. The project aims to develop high-resolution computational models for pandemic mitigation and control, focussing on the novel coronavirus and its emerging variants, and leveraging demographic, genomic and epidemiological data. It expects to rigorously compare multi-scale effects of complex vaccination and social distancing strategies and quantify optimal responses under the COVID-19 induced uncertainty. The intended outcomes ....High-resolution multiscale modelling of pandemics: COVID-19 and beyond. The project aims to develop high-resolution computational models for pandemic mitigation and control, focussing on the novel coronavirus and its emerging variants, and leveraging demographic, genomic and epidemiological data. It expects to rigorously compare multi-scale effects of complex vaccination and social distancing strategies and quantify optimal responses under the COVID-19 induced uncertainty. The intended outcomes include computational models of how the most infectious viral variants emerge and spread in presence of interventions, how to predict the outbreaks, and which are the most vulnerable communities. This should make a significant economic and social impact, improving population health while maintaining a resilient economy.Read moreRead less
Quantifying emergence and dynamics of foodborne epidemics in Australia. The project aims to greatly improve the accuracy and scope of computational epidemiological models predicting emergence and evolution of foodborne diseases in Australia. It expects to reveal key pathways for both biological evolution of microorganisms, and their spread though food supply chains and human interactions. The intended outcomes include discovering how the most dominant strains of foodborne infection emerge and se ....Quantifying emergence and dynamics of foodborne epidemics in Australia. The project aims to greatly improve the accuracy and scope of computational epidemiological models predicting emergence and evolution of foodborne diseases in Australia. It expects to reveal key pathways for both biological evolution of microorganisms, and their spread though food supply chains and human interactions. The intended outcomes include discovering how the most dominant strains of foodborne infection emerge and self-organise in complex networks, how to predict and contain the epidemics closer to their source, and which are the most vulnerable groups and communities. This should make a significant economic and social impact, improving health of the population, while also safeguarding national and international supply chains.Read moreRead less