Bridging the interface between nanoengineered materials and biological systems. Advances in nanotechnology have the potential to revolutionise how we treat many diseases. Nanoengineered drug carriers can deliver drugs to the areas in the body where they are required, limiting harmful side effects. This project will investigate how nanomaterials interact with biological systems and understand any potential side effects.
Nanoengineered gradient substrata as a novel approach for understanding infection mechanisms. This project will advance our understanding of how bacteria colonise surfaces and will also inform the development of novel antibacterial coatings and diagnostic tools for device-associated infections, which have a significant impact on patients and are a huge burden to the healthcare system.
Multiplexed surface signals to inhibit mixed bacterial biofilm formation. This project aims to investigate a novel class of multifunctional surfaces that can be used to coat biomaterials with antimicrobial properties. This combines advanced polymer synthesis with a new colloidal particle self-assembly technique to modify surfaces. Expected project outcomes are generation of new knowledge of the molecular mechanisms of biofilm formation in complex microbial communities, which may facilitate futur ....Multiplexed surface signals to inhibit mixed bacterial biofilm formation. This project aims to investigate a novel class of multifunctional surfaces that can be used to coat biomaterials with antimicrobial properties. This combines advanced polymer synthesis with a new colloidal particle self-assembly technique to modify surfaces. Expected project outcomes are generation of new knowledge of the molecular mechanisms of biofilm formation in complex microbial communities, which may facilitate future research exploring the development of biomaterials that resist attachment of infectious microbes, which is desperately needed in many biomedical application areas. This can assist entrepreneurs and researchers in the medical technologies sector, allowing them to explore how to reduce infection rates on medical devices.Read moreRead less