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Targeted Nutrition To Improve Maternal And Child Health Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Nutrition is vitally important to support the rapid growth and development occurring from conception to a child’s second birthday – the first 1000 days. Failure to meet nutritional needs during this critical period can have profound consequences for lifelong health. Through our CRE in Targeted Nutrition to Improve Maternal and Child Health Outcomes, we will provide nutritional interventions which optimise a mother’s health outcomes and ensure her children achieve their full potential.
Adequate nutrition is necessary for recovery from illness. 30-40% of hospitalised patients may be malnourished. The critically ill are at higher risk because of increased energy requirements yet often receive less than 50% of required nutritional intake. Adequate nutrition therapy is associated with improved patient outcomes, such as reduced mortality and reduced infectious complications. Robust strategies to implement of evidence-based recommendations for nutrition therapy are required.
Poorly-controlled gestational diabetes mellitus (GDM) can have negative outcomes for mother and baby. Nutrition counselling is the first line strategy to manage GDM and can prevent the need for insulin. No Australian GDM nutrition practice guidelines (NPGs) exist, but better outcomes have been shown in America following a evidence-based schedule of dietary counselling. This project will investigate implementation of American NPGs in an Australian setting, using the latest nutrition advice.
A Dietary Intervention In Gestational Diabetes To Reduce Child Obesity: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$354,715.00
Summary
Women with gestational diabetes (GDM) whose blood glucose levels (BGL) are not well controlled have a higher chance of giving birth to large babies. These babies are at high risk of becoming overweight children and adults. Preventing child obesity therefore requires appropriate intervention during pregnancy complicated with GDM. This study will determine the ability of specific dietary advice (aimed at reducing maternal BGL) to reduce the risk of large babies in a typical ante-natal setting.
Protein Preloads To Improve Postprandial Glycaemia In Type 2 Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$624,458.00
Summary
Taking a high protein drink can substantially lower the blood glucose rise after a subsequent meal in people with type 2 diabetes. We will examine whether regular use of protein drinks before meals can be effective for improving long-term blood glucose control. Such an approach could represent an exciting new nutritional strategy for managing this increasingly common disorder.
The Alternate Day Fasting Diet In Adolescents With Obesity: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,007,545.00
Summary
One in four Australian adolescents is overweight or obese. While short-term weight loss is possible, keeping the weight off long term is difficult. We will test whether the alternate day fasting diet is effective, safe and acceptable to adolescents. We will undertake a trial involving adolescents aged 13-17 years who are affected by obesity: they will be randomised to receive either the alternate day fasting diet, or a standard weight control diet.
Determining The Affect And Cost Effectiveness Of Nutrition In Critically Ill Patients From Intensive Care Unit Admission To Hospital Discharge.
Funder
National Health and Medical Research Council
Funding Amount
$138,964.00
Summary
Nutrition when you are severely unwell is very important to support recovery. Research is required to determine exactly how much nutrition is needed in severely ill patients to ensure their best recovery. This project aims to determine what effect nutrition has on clinical and functional outcomes of patients who are severely ill during their whole hospital stay. It will also aim to determine the cost effectiveness of nutrition for these patients.
Changing Therapeutic Paradigms For Intestinal Health: Diet As A Therapeutic Strategy In Gastroenterology.
Funder
National Health and Medical Research Council
Funding Amount
$640,210.00
Summary
Irritable bowel syndrome (IBS) affects 1 in 7 adults in Australia. IBS symptoms include abdominal pain, bloating and wind. My team has shown that fermentable short chain carbohydrates (FODMAPs) present in many foods are responsible for triggering these symptoms. The Low FODMAP diet is now being adopted worldwide as first-line management therapy for IBS. The delivery of this research worldwide has been possible through the use of a smartphone app: The Monash Uni Low FODMAP diet.