Lipidomics Associated with Metabolic Syndrome, Aging and Metabolic Variation between Species. The aim is to apply state-of?the-art mass spectrometry to identify and quantify alterations in membrane lipidomes (i.e. lipid classes, molecular species, structure alterations and by-products) related to two major health problems facing Australia i.e. the Metabolic Syndrome and an Ageing population plus insight into the variation in metabolic rate between organisms. This research offers the opportunity ....Lipidomics Associated with Metabolic Syndrome, Aging and Metabolic Variation between Species. The aim is to apply state-of?the-art mass spectrometry to identify and quantify alterations in membrane lipidomes (i.e. lipid classes, molecular species, structure alterations and by-products) related to two major health problems facing Australia i.e. the Metabolic Syndrome and an Ageing population plus insight into the variation in metabolic rate between organisms. This research offers the opportunity for the development of mass spectrometry based technologies for the early clinical diagnosis of metabolic disorders plus provides a template of information for our Linkage partner (AstraZeneca) to develop pharmaceutical therapies targeting key molecular lipid species identified as critical to particular membrane functions.Read moreRead less
Community preferences for organ donation and allocation in Australia. This work will provide vital information on the Australian public's attitudes and preferences towards organ donation and allocation strategies, and inform the development of a national organ donation strategy that considers the public's preferences for different policies to increase organ donor rates. This project will directly address the National Research Priority of 'promoting and maintaining good health'; increasing the a ....Community preferences for organ donation and allocation in Australia. This work will provide vital information on the Australian public's attitudes and preferences towards organ donation and allocation strategies, and inform the development of a national organ donation strategy that considers the public's preferences for different policies to increase organ donor rates. This project will directly address the National Research Priority of 'promoting and maintaining good health'; increasing the availability of donor organs, and improving the equity and transparency of organ allocation in Australia will lead to improved health outcomes for patients on transplant waiting lists around Australia, and improved health outcomes for patients not previously eligible for transplant (e.g. some dialysis patients)Read moreRead less
Special Research Initiatives - Grant ID: SR0563610
Funder
Australian Research Council
Funding Amount
$111,115.00
Summary
Developing an E-Platform for Application of Clinical Management in the Human Respiratory and Vascular System. This project aims to develop an E-PLATFORM that will provide a simulation-based virtual reality environment for clinical management and therapy treatment in the human respiratory and vascular system. One significant feature of the expected outcomes is the ability for surgeon or physician to adequately plan their treatment or operation decision-making of respiratory or vascular disease, i ....Developing an E-Platform for Application of Clinical Management in the Human Respiratory and Vascular System. This project aims to develop an E-PLATFORM that will provide a simulation-based virtual reality environment for clinical management and therapy treatment in the human respiratory and vascular system. One significant feature of the expected outcomes is the ability for surgeon or physician to adequately plan their treatment or operation decision-making of respiratory or vascular disease, in particular, from the point of view of flow analysis using state-of-the-art computational fluid dynamics techniques. This research proposal aims to facilitate new medical research and development for treatment of respiratory and/or vascular diseases, which can have a great socioeconomic benefit to the Australian community.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0454017
Funder
Australian Research Council
Funding Amount
$582,598.00
Summary
A unique Western Australian multi-photon confocal microscope facility to support nationally prioritised biomedical, biological and materials research. Core national priority research will utilise the low dose and penetrative nature of multi-photon confocal microscopy in current research into nerve regeneration after neurotrauma, the histopathological treatment of diabetic retinopathology, and hair cell information transfer processes in auditory physiology. Other programs will study biomineralisa ....A unique Western Australian multi-photon confocal microscope facility to support nationally prioritised biomedical, biological and materials research. Core national priority research will utilise the low dose and penetrative nature of multi-photon confocal microscopy in current research into nerve regeneration after neurotrauma, the histopathological treatment of diabetic retinopathology, and hair cell information transfer processes in auditory physiology. Other programs will study biomineralisation in the superior epithelium of chiton and limpet teeth and a variety of salinity-related plant processes. In parallel, an optical development program will investigate contrast modes in other non-linear interactions. The instrument complements and will be managed with field emission SEM, TEM and a unique high-resolution scanning ion probe in a well-established regional Centre.Read moreRead less
Sound practice: Supporting sustainable careers in orchestral musicians through Occupational Health and Safety initiatives. This project will produce new knowledge about musician health, well-being and injury prevention and management. It will establish the first injury surveillance system for musicians internationally and the first set of rigorous studies to evaluate the effectiveness of injury management interventions for orchestral musicians. We will establish musician-specific assessment prot ....Sound practice: Supporting sustainable careers in orchestral musicians through Occupational Health and Safety initiatives. This project will produce new knowledge about musician health, well-being and injury prevention and management. It will establish the first injury surveillance system for musicians internationally and the first set of rigorous studies to evaluate the effectiveness of injury management interventions for orchestral musicians. We will establish musician-specific assessment protocols, practices and interventions leading to effective OHS policies, thus enabling global improvement in OHS in the music industry, preventing economic and personal loss from premature career termination due to injury, and assisting, through mentoring, the new generation of young orchestral musicians.Read moreRead less
Examining the complexity of communication processes across transition points from the emergency department to improve medication safety. Problems in communication contribute significantly to adverse events that lead to serious harm for Australian consumers. Recent data show medication errors account for over 25% of all adverse events, while over 50% of consumers who move across transition points have medication errors relating to their treatment regimen. Financial costs from adverse events are e ....Examining the complexity of communication processes across transition points from the emergency department to improve medication safety. Problems in communication contribute significantly to adverse events that lead to serious harm for Australian consumers. Recent data show medication errors account for over 25% of all adverse events, while over 50% of consumers who move across transition points have medication errors relating to their treatment regimen. Financial costs from adverse events are estimated at around $A2billion/year, which are likely to increase with further complexities involving consumer care. This study will result in new knowledge about communication processes to inform the development of reporting methods and strategies, which positively influence the practices of health professionals in managing medications as consumers move across different environments.Read moreRead less
Preventing Adverse Events in Hospitals. Our research will construct strategies and tools for preventing hospital adverse events and should develop knowledge and expertise about reducing care complications in high risk patients.This research has collaborating partners which are hospitals in Victoria, South Australia and Queensland. These form part of the preventative healthcare network with implications for the nation's social and economic fabric through their role in reducing morbidity, mortali ....Preventing Adverse Events in Hospitals. Our research will construct strategies and tools for preventing hospital adverse events and should develop knowledge and expertise about reducing care complications in high risk patients.This research has collaborating partners which are hospitals in Victoria, South Australia and Queensland. These form part of the preventative healthcare network with implications for the nation's social and economic fabric through their role in reducing morbidity, mortality and supporting the health of all Australians. Since acquired complications have comparable costs to the healthcare system as that of all other forms of injury combined, there will be substantial benefits to hospitals through reduced costs.Read moreRead less