Energetics and dynamics of solvated biologically relevant molecules using liquid microjet and ion imaging technologies. The shape of many biomolecules in solution plays a critical role in determining their biological activity and function. It is known that the bonds that form between the biomolecules and the water solvent control this shape. However, very little is known about the strength and structure of these bonds at different sites around the biomolecule. Many experiments have informed u ....Energetics and dynamics of solvated biologically relevant molecules using liquid microjet and ion imaging technologies. The shape of many biomolecules in solution plays a critical role in determining their biological activity and function. It is known that the bonds that form between the biomolecules and the water solvent control this shape. However, very little is known about the strength and structure of these bonds at different sites around the biomolecule. Many experiments have informed us about the strength of the bonds, others have told us where the bonds occur. This project will provide both pieces of information for the first time, allowing us to better understand, and therefore control, biological function. This work will assist in the development of new biotechnology processes, especially in the emerging area of proteomics.Read moreRead less
Growth dynamics and innovative spectroscopic techniques for real-time control of advanced electronics materials grown by molecular beam epitaxy. Many important semiconductor devices for communications, lasers, high speed electronics and optical sensing are based on materials grown by Molecular Beam Epitaxy (MBE). This research will provide the first measurements of the reactions taking place during MBE and thus enable accurate growth of the complex multi-layered material required for improved se ....Growth dynamics and innovative spectroscopic techniques for real-time control of advanced electronics materials grown by molecular beam epitaxy. Many important semiconductor devices for communications, lasers, high speed electronics and optical sensing are based on materials grown by Molecular Beam Epitaxy (MBE). This research will provide the first measurements of the reactions taking place during MBE and thus enable accurate growth of the complex multi-layered material required for improved semiconductor devices. In particular, this project will make a major contribution to Australia's established capability to produce and develop state-of-the art infrared sensors as required for defence applications, remote sensing of minerals and pollutants, chemical analysis, and health diagnostics. PhD students will be trained in advanced semiconductor growth and optical sensing technologies.Read moreRead less
In situ Raman spectroscopic studies of iron and calcium biomaterials in marine chiton teeth. The future of biomaterial science in Australia depends upon the discovery and refinement of new materials. This project characterizes the biomaterials in the feeding apparatus of Australian marine chitons (Mollusca: Polyplacophora). Like many biological structures, chiton teeth are sophisticated composite materials that have been refined by evolution over millions of years. Initially composed of the poly ....In situ Raman spectroscopic studies of iron and calcium biomaterials in marine chiton teeth. The future of biomaterial science in Australia depends upon the discovery and refinement of new materials. This project characterizes the biomaterials in the feeding apparatus of Australian marine chitons (Mollusca: Polyplacophora). Like many biological structures, chiton teeth are sophisticated composite materials that have been refined by evolution over millions of years. Initially composed of the polysaccharide chitin, these extremely hard teeth are mineralized with calcium and iron compounds and used to excavate the rocks on which they live, as they graze for food. Understanding the mechanism of biomineralization is vital for devising synthetic routes to composite materials for industrial purposes.Read moreRead less