Development of a Novel Process for the Formation of Polymer Vesicles. The project would provide an increased understanding of polymer structures, polymer-drug interactions and dense gas processing of polymers. The novel process developed would be beneficial on a manufacturing level since it dramatically reduces processing time and minimises energy requirements. The research to be conducted is leading-edge technology that will attract business from international polymer, drug and biotechnology co ....Development of a Novel Process for the Formation of Polymer Vesicles. The project would provide an increased understanding of polymer structures, polymer-drug interactions and dense gas processing of polymers. The novel process developed would be beneficial on a manufacturing level since it dramatically reduces processing time and minimises energy requirements. The research to be conducted is leading-edge technology that will attract business from international polymer, drug and biotechnology companies. The development of world-class research provides Australia with recognition as a world leader in the field and strengthens and broadens the knowledge base of Australian scientists and engineers.Read moreRead less
Degradable hollow microspheres for liver cancer treatment. The expected outcome of this multidisciplinary approach is a controlled drug delivery system for the treatment of liver cancer. We aim to increase the understanding of drug release using polymeric microspheres and the influence of the polymer properties on the release kinetics resulting in the tailored drug release for liver cancer treatment. An indepth knowledge in drug delivery can lead to optimised release kinetics leding to an increa ....Degradable hollow microspheres for liver cancer treatment. The expected outcome of this multidisciplinary approach is a controlled drug delivery system for the treatment of liver cancer. We aim to increase the understanding of drug release using polymeric microspheres and the influence of the polymer properties on the release kinetics resulting in the tailored drug release for liver cancer treatment. An indepth knowledge in drug delivery can lead to optimised release kinetics leding to an increased patient convenience and life prolonging treatments.Read moreRead less
Oral Insulin Delivery facilitated by Enteric Coating using Dense Gas Technologies. Insulin dependant diabetes is a rapidly growing disease. The current method for insulin delivery to the patient is by injection, which is inconvenient. Oral delivery of insulin is a more acceptable method. It is proposed to develop a dense gas technique to coat insulin with a pH sensitive polymer to protect it from the acidic environment of the stomach. Insulin can then be released at the high pH of the intestin ....Oral Insulin Delivery facilitated by Enteric Coating using Dense Gas Technologies. Insulin dependant diabetes is a rapidly growing disease. The current method for insulin delivery to the patient is by injection, which is inconvenient. Oral delivery of insulin is a more acceptable method. It is proposed to develop a dense gas technique to coat insulin with a pH sensitive polymer to protect it from the acidic environment of the stomach. Insulin can then be released at the high pH of the intestine when the polymer is dissolved. Particle size control is feasible by dense gas processes by manipulating operating parameters. Advantages include low residual solvent and manufacture at ambient temperatures.Read moreRead less