Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fu ....Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fundamentally understand the relationship between physical-chemical properties and efficacy. Completion of this project aims to produce potent nanoparticle-based adjuvants underpinned by novel manufacturing technology, to ultimately facilitate the development of more effective and protective vaccines for animals and humans.Read moreRead less
Desalting reclaimed wastewater to safeguard Virginia's horticultural industries. Virginia is a major horticultural region of South Australia undergoing rapid expansion. Groundwater resources are depleted and reclaimed sewage effluent from Adelaide is required for irrigation. Unfortunately, the effluent is frequently too saline. Large-scale desalting is being considered. A pilot-scale plant will be built to evaluate suitable desalting processes (e.g. reverse osmosis) for reducing the effluent ....Desalting reclaimed wastewater to safeguard Virginia's horticultural industries. Virginia is a major horticultural region of South Australia undergoing rapid expansion. Groundwater resources are depleted and reclaimed sewage effluent from Adelaide is required for irrigation. Unfortunately, the effluent is frequently too saline. Large-scale desalting is being considered. A pilot-scale plant will be built to evaluate suitable desalting processes (e.g. reverse osmosis) for reducing the effluent's salt content. Original research will: (i) synthesize the best combination of technologies to produce effluent streams of varying salinity for matching different crop requirements; and (ii) optimise delivery and storage of effluent streams using new storage(s) and the region's multiple aquifer and surface storages.Read moreRead less
Multi-scale strategy to manage chloramine decay and nitrification in water distribution systems. The generation of knowledge and technologies in preventing chloramine decay would greatly benefit the Australian water industry. The success of the project would provide the highest possible quality of water, both economically and reliably, giving public assurances of microbiological compliance and safe drinking water.
Controlling arsenic to unlock value in gold and copper resources. This project aims to characterise the transformation of arsenic between oxidation states during mineral processing. Up to one third of the world’s gold reserves are locked up in arsenic rich minerals and 5000 tonnes of arsenic is released annually from mine waste. The project will enable the development of process technology that immobilises and removes arsenic at the earliest possible stage. The use of novel time-resolved in-situ ....Controlling arsenic to unlock value in gold and copper resources. This project aims to characterise the transformation of arsenic between oxidation states during mineral processing. Up to one third of the world’s gold reserves are locked up in arsenic rich minerals and 5000 tonnes of arsenic is released annually from mine waste. The project will enable the development of process technology that immobilises and removes arsenic at the earliest possible stage. The use of novel time-resolved in-situ techniques proposed in this research will give vital information of the complex chemical pathways involved during processing which current characterization methods on pre- and post-processed species do not achieve.Read moreRead less