Australian Laureate Fellowships - Grant ID: FL140100027
Funder
Australian Research Council
Funding Amount
$2,898,150.00
Summary
Under the hood: single-molecule studies of multi-protein machines. Under the hood: single-molecule studies of multi-protein machines. Living cells are filled with complex protein machines that are responsible for the molecular processes supporting life. This project is aimed towards the development of physical tools that enable the study of these protein complexes at the level of single molecules. This project aims to study the protein machinery responsible for DNA replication, the process of du ....Under the hood: single-molecule studies of multi-protein machines. Under the hood: single-molecule studies of multi-protein machines. Living cells are filled with complex protein machines that are responsible for the molecular processes supporting life. This project is aimed towards the development of physical tools that enable the study of these protein complexes at the level of single molecules. This project aims to study the protein machinery responsible for DNA replication, the process of duplicating genomic information before cell division. By making real-time single-molecule movies of the replication process, this project aims to unravel the molecular mechanisms of this important process and provide the knowledge required to understand disease mechanisms and catalyse drug development.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100100
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
Biophysical surface characterisation facility. This facility will allow advances in our understanding of the molecular processes involved in the formation and stability of surface structures of bio-molecules, as well as in the design of molecular machines based on this new understanding.
Linkage Infrastructure, Equipment And Facilities - Grant ID: Le110100100
Funder
Australian Research Council
Summary
Biophysical surface characterisation facility. This facility will allow advances in our understanding of the molecular processes involved in the formation and stability of surface structures of bio-molecules, as well as in the design of molecular machines based on this new understanding.
Evolution of the light harvesting system in cryptophyte algae: protein structure to quantum coherence. The purpose of this project is to understand how algae have evolved highly efficient antenna protein systems to capture solar energy when light is scarce and how these systems use quantum physics. The outcome will be an atomic understanding of the antennae, how they are organised and how their design optimises energy capture which may lead to new technologies.