Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453608
Funder
Australian Research Council
Funding Amount
$579,230.00
Summary
Multifunctional confocal laser scanning microscope with time resolved and two photon imaging and fluorescence correlation capabilities. We seek to establish an Australian first confocal laser scanning microscope with time resolved imaging and fluorescence correlation spectroscopy capabilities. Its advantages include ultrasensitive detection of weak fluorescent emissions against high autofluorescent background by using fluorescence lifetime signatures, with over three orders of magnitude discrimi ....Multifunctional confocal laser scanning microscope with time resolved and two photon imaging and fluorescence correlation capabilities. We seek to establish an Australian first confocal laser scanning microscope with time resolved imaging and fluorescence correlation spectroscopy capabilities. Its advantages include ultrasensitive detection of weak fluorescent emissions against high autofluorescent background by using fluorescence lifetime signatures, with over three orders of magnitude discrimination improvement. The system will also be able to monitor binding of single molecules. These techniques will open new and exciting avenues for interdisciplinary research at the frontier between biological and physical sciences. The microscope will operate within an existing multi-user Optical Characterisation Facility supporting research of an established network of scientists in the Sydney area.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668417
Funder
Australian Research Council
Funding Amount
$108,667.00
Summary
New-Generation Near Infrared Spectrometer for Ecological Research. Sustainable use of the natural resources of Australia depends on studies that define how ecological communities respond to disturbance and change. An important part of this is understanding how the composition of plants and animals such as insects, change reflecting for example, increased concentrations of toxins. However making large numbers of analyses is expensive and slow. Near infrared spectroscopy is a non-destructive an ....New-Generation Near Infrared Spectrometer for Ecological Research. Sustainable use of the natural resources of Australia depends on studies that define how ecological communities respond to disturbance and change. An important part of this is understanding how the composition of plants and animals such as insects, change reflecting for example, increased concentrations of toxins. However making large numbers of analyses is expensive and slow. Near infrared spectroscopy is a non-destructive analytical method that allows the composition of materials to be deduced based on their interaction with light. Adopting these methods in ecology will allow many samples to be analysed quickly and cheaply and also stop waste and duplication of analytical work.Read moreRead less
Novel biomaterials from improved understanding of the structure of starch. The microstructure of starch, comprising two polymers of glucose: amylose (linear, except for a few long branches) and amylopectin (with a complex tree-like architecture), is described by a high-dimensional function. This project examines simplified measures of the full microstructure, such as the distribution of lengths if all links were cut, and also properties which depend on the full architecture, such as viscoelastic ....Novel biomaterials from improved understanding of the structure of starch. The microstructure of starch, comprising two polymers of glucose: amylose (linear, except for a few long branches) and amylopectin (with a complex tree-like architecture), is described by a high-dimensional function. This project examines simplified measures of the full microstructure, such as the distribution of lengths if all links were cut, and also properties which depend on the full architecture, such as viscoelastic response and adhesion. Theory, simulation and neural networks will be used to guide experiments to elucidate which partial structure measures control which property. Outcomes will include means of helping biotechnology create improved biomaterials, and plant breeders to improve food quality.Read moreRead less