Silk Fibroin Optofluidic Chips. Unlike any other material, even any other biologically occurring material, silk is unique in being very transparent, able to be shaped on a very small scale and can keep natural chemicals like proteins and enzymes active. This project will use silk to make optical devices and sensors. Optics made from silk will have all these properties, which means that they can be used as sensors and devices in biochemistry applications that have never been possible before. Thes ....Silk Fibroin Optofluidic Chips. Unlike any other material, even any other biologically occurring material, silk is unique in being very transparent, able to be shaped on a very small scale and can keep natural chemicals like proteins and enzymes active. This project will use silk to make optical devices and sensors. Optics made from silk will have all these properties, which means that they can be used as sensors and devices in biochemistry applications that have never been possible before. These cost-effective devices will have the potential to enhance healthcare, emergency medicine and assist early medical diagnosis.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989615
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Melbourne Platform for Surface Characterisation of Structured Materials. The Australian economy is gradually expanding its manufacturing base through the development of the nanotechnology and biotechnology sectors. This will lead to production of a more diverse range of elaborately transformed goods. A key contributor to these export opportunities will be the nanotechnology sector since at the present time no country has a real nanotechnology based economy and there are many niche markets availa ....Melbourne Platform for Surface Characterisation of Structured Materials. The Australian economy is gradually expanding its manufacturing base through the development of the nanotechnology and biotechnology sectors. This will lead to production of a more diverse range of elaborately transformed goods. A key contributor to these export opportunities will be the nanotechnology sector since at the present time no country has a real nanotechnology based economy and there are many niche markets available for smaller countries such as Australia. This proposal helps to build quality control and characterisation infrastructure that will facilitate prototyping and design of nanoscale devices and sensors for next generation manufacturing.Read moreRead less
Miniaturised Adiabatic Light Processing Devices. The project will develop, model and analyse a range of miniaturised light-processing devices for optical communications applications that rely soley on their geometrical design for their optical functionality. Such devices are less complex than devices that rely on other physical phenomena for their operation, such as interference, resonance or grating phenomena. They have potential application to a wide range of applications including optical tel ....Miniaturised Adiabatic Light Processing Devices. The project will develop, model and analyse a range of miniaturised light-processing devices for optical communications applications that rely soley on their geometrical design for their optical functionality. Such devices are less complex than devices that rely on other physical phenomena for their operation, such as interference, resonance or grating phenomena. They have potential application to a wide range of applications including optical telecommunications, optical sensing and biophotonics. The major outcome will be a range of novel devices that are very compact, have very low optical power loss and process light signals in ways that either cannot be readily achieved by other approaches or are simpler than other approaches.Read moreRead less
Light-matter interactions using optical fibres. This program will allow Australia to build on established excellence in photonics to extend the impact of optical fibres beyond telecommunications to applications throughout the sciences. Pioneering work on materials and structures will form a platform technology enabling innovations in areas as diverse as water quality monitoring and corrosion detection. In addition, new optical fibres will be developed for the needs of the Australian Defence Forc ....Light-matter interactions using optical fibres. This program will allow Australia to build on established excellence in photonics to extend the impact of optical fibres beyond telecommunications to applications throughout the sciences. Pioneering work on materials and structures will form a platform technology enabling innovations in areas as diverse as water quality monitoring and corrosion detection. In addition, new optical fibres will be developed for the needs of the Australian Defence Force and associated industries. Fibre-based approaches to problems in biology will ultimately lead to an improved understanding of molecular structures and new tools for manipulating biomolecules.Read moreRead less
Novel Carbon Nanotube Composite Materials: Elucidation of key properties for device development. As the former co-director of CSIRO Nanotechnology indicated to the Sydney Morning Herald in 2003, 'Nanotechnology will lead us into a very different future.' The proposed research on nanomaterial interactions and biomolecular incorporation protocols will provide a foundation for future bioelectronic devices. Imagine healthcare of human diseases when nanocomponents enable the design of new platforms f ....Novel Carbon Nanotube Composite Materials: Elucidation of key properties for device development. As the former co-director of CSIRO Nanotechnology indicated to the Sydney Morning Herald in 2003, 'Nanotechnology will lead us into a very different future.' The proposed research on nanomaterial interactions and biomolecular incorporation protocols will provide a foundation for future bioelectronic devices. Imagine healthcare of human diseases when nanocomponents enable the design of new platforms for devices that give point-of-care diagnosis, or the impact on the semiconductor industry with the creation of flexible electronics. Educational outreach is an important aim of the project, providing effective research training for early career researchers.Read moreRead less
Biomolecular films on silicon substrates. Construction of hybrid carbon-silicon devices in which molecular organic molecular films are covalently linked to silicon wafers. Biomolecular nanostructures on silicon wafers can be studied using unique impedance spectroscopy instrumentation that we have developed as well as X-ray and neutron reflectometry. The system will be used to study a variety of molecular films as well as molecularly tethered lipid bilayer membranes that mimic aspects of cell mem ....Biomolecular films on silicon substrates. Construction of hybrid carbon-silicon devices in which molecular organic molecular films are covalently linked to silicon wafers. Biomolecular nanostructures on silicon wafers can be studied using unique impedance spectroscopy instrumentation that we have developed as well as X-ray and neutron reflectometry. The system will be used to study a variety of molecular films as well as molecularly tethered lipid bilayer membranes that mimic aspects of cell membranes and these will be used to investigate the effect of sterols on such membranes.Read moreRead less
Enabling Technologies for Motion Corrected Positron Emission Tomography (PET) of Unanaesthetized Laboratory Animals. Small animal molecular imaging is a powerful tool in biological research and drug discovery. Anaesthesia is routinely used to avoid motion distortion, but can profoundly alter the biological process studied. This research will enable quantitative imaging of neurobiological phenomena in awake laboratory animals. It will create new opportunities for Australian basic researchers to ....Enabling Technologies for Motion Corrected Positron Emission Tomography (PET) of Unanaesthetized Laboratory Animals. Small animal molecular imaging is a powerful tool in biological research and drug discovery. Anaesthesia is routinely used to avoid motion distortion, but can profoundly alter the biological process studied. This research will enable quantitative imaging of neurobiological phenomena in awake laboratory animals. It will create new opportunities for Australian basic researchers to use innovative technology with expected high economic potential, and benefit small biotech companies by facilitating pre-clinical and clinical development of new pharmaceuticals. The new motion tracking and image reconstruction technologies developed will strengthen Australia's leading position in engineering and biomedical systems development.Read moreRead less
Opto-Microfluidics: A Rapid and Sensitive Platform for Biological Diagnostics. One in four people above 25 years suffer from diabetes-related diseases in Australia, with an associated economic cost exceeding $3 billion a year. A microdevice for continuous glucose monitoring would help patients to manage the disease, leading to huge individual, clinical and societal benefits. Life expectancy is expected to increase along with quality of life. Integration of the microdevice with insulin delivery w ....Opto-Microfluidics: A Rapid and Sensitive Platform for Biological Diagnostics. One in four people above 25 years suffer from diabetes-related diseases in Australia, with an associated economic cost exceeding $3 billion a year. A microdevice for continuous glucose monitoring would help patients to manage the disease, leading to huge individual, clinical and societal benefits. Life expectancy is expected to increase along with quality of life. Integration of the microdevice with insulin delivery would realise an 'artificial pancreas', revolutionising the management and treatment of the disease. The technology will also provide a platform for other point-of-care medical diagnostic devices, which will allow early participation in this emerging market and cement Australia's position in bionanotechnology.Read moreRead less
Quantum Nanoscience. This project will deliver a new Australian capability in the core nanotechnology of quantum electromechanical systems. Nanotechnology is a suite of techniques and processes to create new materials and devices through complex processing of constituents at the nanoscale and, in the case of quantum electromechanical systems, even with moving parts. At the nanoscale, quantum principles apply. New nano-fabrication methods are now available to build nano-electromechanical systems ....Quantum Nanoscience. This project will deliver a new Australian capability in the core nanotechnology of quantum electromechanical systems. Nanotechnology is a suite of techniques and processes to create new materials and devices through complex processing of constituents at the nanoscale and, in the case of quantum electromechanical systems, even with moving parts. At the nanoscale, quantum principles apply. New nano-fabrication methods are now available to build nano-electromechanical systems (NEMS), integrated with electronics and nano optics and cooled into the quantum regime. Quantum electromechanical systems (QEMS) enable new sensors with ultimate sensitivity limited only by the Heisenberg uncertainty principle, with applications in photonics, metrology and bio molecular imaging.Read moreRead less