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Industrial Transformation Research Hubs - Grant ID: IH210100051
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
The ARC Research Hub for Digital Bioprocess Development. The ARC Hub for Digital Bioprocess Development aims to assist the Biopharma industry by increasing digital innovation, productivity and competitiveness. An interdisciplinary team of engineers, scientists and computing specialists will develop digitally integrated advanced manufacturing processes and a platform for industry adoption. The program will address key bioprocessing research challenges and develop new process and digital models th ....The ARC Research Hub for Digital Bioprocess Development. The ARC Hub for Digital Bioprocess Development aims to assist the Biopharma industry by increasing digital innovation, productivity and competitiveness. An interdisciplinary team of engineers, scientists and computing specialists will develop digitally integrated advanced manufacturing processes and a platform for industry adoption. The program will address key bioprocessing research challenges and develop new process and digital models that can predict and optimise manufacturing processes, resulting in greater yields, faster and more flexible processes and enhanced product stability. The Hub will transform biopharmaceutical manufacturing and unlock growth opportunities to forge an internationally competitive Australian Biopharma sector.Read moreRead less
Development of electrophoretic cell sorters. The aim of this research is to develop the next generation of cell sorters to scale production of viable sperm and other cell types. Our approach is to understand the factors that control the migration of cells in an electric field so that we can design large-scale devices to purify cells using electrophoretic separation. The outcomes of this research enable large-scale production of viable sperm for human and animal-assisted conception, benefiting in ....Development of electrophoretic cell sorters. The aim of this research is to develop the next generation of cell sorters to scale production of viable sperm and other cell types. Our approach is to understand the factors that control the migration of cells in an electric field so that we can design large-scale devices to purify cells using electrophoretic separation. The outcomes of this research enable large-scale production of viable sperm for human and animal-assisted conception, benefiting infertile couples and the livestock breeding industry. Successful development of an efficient cell separation technology would add significant commercial value to the Australian biomanufacturing sector. Read moreRead less
A New Platform for Developing a Compound Against Herpes Simplex Virus. This project aims to further explore the research team’s recent fundamental discovery of a protein found naturally in an Australian abalone that inhibits viral entry by blocking three key viral glycoproteins. We would aim to utilise this knowledge towards development of a new class of therapeutics against Herpes simplex viruses (HSV) and their consequent infections. The new therapeutics could overcome the low bioavailability ....A New Platform for Developing a Compound Against Herpes Simplex Virus. This project aims to further explore the research team’s recent fundamental discovery of a protein found naturally in an Australian abalone that inhibits viral entry by blocking three key viral glycoproteins. We would aim to utilise this knowledge towards development of a new class of therapeutics against Herpes simplex viruses (HSV) and their consequent infections. The new therapeutics could overcome the low bioavailability of current drugs and thus significantly shorten the recurrence period. Such new drugs may have broad applicability.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC130100009
Funder
Australian Research Council
Funding Amount
$2,100,000.00
Summary
ARC Training Centre for Molecular Technology in the Food Industry. A molecular technology platform for enabling the next revolution in the food industry. Society needs new approaches for solving the difficulties of providing enough food for the future. This Training Centre will train young scientists in the application of applying molecular analysis skills to solve specific problems that the food industry faces in the whole process of taking food production from “field to fork”.
High performance bioderived hybrid fillers for rubber composite. This project aims to address a significant problem in polymer composite synthesis by production and application of high performance bioderived hybrid silica fillers from renewable biomass feedstock. The project expects to generate new knowledge in the area of advanced manufacturing using interdisciplinary approaches in biorefining, filler and composite production and characterization. Expected outcomes of this project include a mo ....High performance bioderived hybrid fillers for rubber composite. This project aims to address a significant problem in polymer composite synthesis by production and application of high performance bioderived hybrid silica fillers from renewable biomass feedstock. The project expects to generate new knowledge in the area of advanced manufacturing using interdisciplinary approaches in biorefining, filler and composite production and characterization. Expected outcomes of this project include a more sustainable filler production process for producing novel bioderived silica fillers with properties superior to commercial silica fillers. The successful implementation of this project will lead to the development of a new advanced manufacturing industry, creating jobs in regional Australia. Read moreRead less
Algal control using multi-functional, cold plasma activated microbubbles . Climate change is driving a proliferation of nuisance and harmful algal blooms in our water supply systems, which urgently require cost efficient and effective control strategies. Paradoxically, algal biotechnology is a growth industry with application in food, agriculture and energy; realising this potential requires state-of-the-art technology to optimise production, harvesting and extraction. The aim of this proposal i ....Algal control using multi-functional, cold plasma activated microbubbles . Climate change is driving a proliferation of nuisance and harmful algal blooms in our water supply systems, which urgently require cost efficient and effective control strategies. Paradoxically, algal biotechnology is a growth industry with application in food, agriculture and energy; realising this potential requires state-of-the-art technology to optimise production, harvesting and extraction. The aim of this proposal is to develop cutting edge technology that uses cold plasma activated microbubbles to control algal populations. We propose that by tuning the plasma composition, this technology could both selectively disrupt and destroy algal matter and enhance algal cell growth, benefiting both water and biotechnology industries. Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH180100006
Funder
Australian Research Council
Funding Amount
$4,995,391.00
Summary
ARC Research Hub for Medicinal Agriculture . The ARC Research Hub for Medicinal Agriculture aims to transform the production of high quality plant-derived therapeutics into an integrated, national industry that spans primary producers and manufacturers. The Hub will establish a multi-disciplinary collaboration with industry. This Hub will address agronomy and cultivation, germplasm generation, novel extraction technologies and chemistries, through to the discovery and functional characterisation ....ARC Research Hub for Medicinal Agriculture . The ARC Research Hub for Medicinal Agriculture aims to transform the production of high quality plant-derived therapeutics into an integrated, national industry that spans primary producers and manufacturers. The Hub will establish a multi-disciplinary collaboration with industry. This Hub will address agronomy and cultivation, germplasm generation, novel extraction technologies and chemistries, through to the discovery and functional characterisation of novel lead compounds. This knowledge will be applicable across related industries and build the specialised workforce needed to underpin Australia’s developing medicinal agriculture industry.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100040
Funder
Australian Research Council
Funding Amount
$4,997,903.00
Summary
ARC Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB). The Centre for Facilitated Advancement of Australia's Bioactives (FAAB) will transform the rapidly growing bioactive ingredients sector. It will apply advanced analytical methods to molecular characterisation of bioactive products derived from foods, food-waste, and cell-based biotechnologies. FAAB will determine modes of action for bioactives with potential lifestyle and nutritional benefits allowing for evidence- ....ARC Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB). The Centre for Facilitated Advancement of Australia's Bioactives (FAAB) will transform the rapidly growing bioactive ingredients sector. It will apply advanced analytical methods to molecular characterisation of bioactive products derived from foods, food-waste, and cell-based biotechnologies. FAAB will determine modes of action for bioactives with potential lifestyle and nutritional benefits allowing for evidence-informed decision-making, and regulatory framework development. FAAB graduates will lead and deliver future national self-reliance to the Australian bioactives sector, increasing diversification and international competitiveness and development of regulation in a growing market. Read moreRead less
Design a Targeted Delivery System for Probiotics. The project aims to improve the effectiveness of probiotics by developing a targeted delivery system to the colon. This interdisciplinary research will generate new knowledge in the field of microbiota and develop new delivery systems for live microorganisms and other active compounds. Expected outcomes include increased understanding of the factors affecting the viability of probiotics during storage and passage through the gastro-intestinal tra ....Design a Targeted Delivery System for Probiotics. The project aims to improve the effectiveness of probiotics by developing a targeted delivery system to the colon. This interdisciplinary research will generate new knowledge in the field of microbiota and develop new delivery systems for live microorganisms and other active compounds. Expected outcomes include increased understanding of the factors affecting the viability of probiotics during storage and passage through the gastro-intestinal tract, the establishment of probiotics into gut flora, and how this incorporation affects the dynamics of gut microbiota. The new technology can be utilised across a wide range of therapeutics that target the colon to promote the well-being of our society through commercialisation by industry partner.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC190100034
Funder
Australian Research Council
Funding Amount
$3,574,272.00
Summary
ARC Training Centre for Green Chemistry in Manufacturing. Globally, there is demand for products that are effective, safe and environmentally benign. The ARC Training Centre for Green Chemistry in Manufacturing aims to utilise local and global experts to provide the next generation of Australian chemists and engineers, with skills to develop innovative products and processes that are intrinsically safe and benign. It will provide collaborating partners and the broader manufacturing industry with ....ARC Training Centre for Green Chemistry in Manufacturing. Globally, there is demand for products that are effective, safe and environmentally benign. The ARC Training Centre for Green Chemistry in Manufacturing aims to utilise local and global experts to provide the next generation of Australian chemists and engineers, with skills to develop innovative products and processes that are intrinsically safe and benign. It will provide collaborating partners and the broader manufacturing industry with new products and processes with strong export potential, and the ability to respond to the market pressures, underpinned by green chemistry and sustainable principles. Resulting benefits include increased competitiveness for Australia's manufacturing industry, jobs, social as well as environmental benefitsRead moreRead less