In situ measurements of the electrostatic properties inside photosynthetic reaction centres: correlation with the energy conversion function of the protein. The photochemical reaction centre is a key protein complex involved in energy conversion. It converts solar energy into chemical energy as a transmembrane charge separation. Coupling of electron and proton transfer is catalysed at the level of a ubiquinone cofactor. In order to understand how the redox properties of this cofactor are fine tu ....In situ measurements of the electrostatic properties inside photosynthetic reaction centres: correlation with the energy conversion function of the protein. The photochemical reaction centre is a key protein complex involved in energy conversion. It converts solar energy into chemical energy as a transmembrane charge separation. Coupling of electron and proton transfer is catalysed at the level of a ubiquinone cofactor. In order to understand how the redox properties of this cofactor are fine tuned by the protein environment, we plan to probe the ubiquinone site using a voltage-sensitive fluorescent dye. This exciting multidisciplinary project will contribute to the understanding of how protein matrices influence and govern the midpoint redox potential of their cofactors and the environments of theirRead moreRead less
Photoactive Semiconducting Biopolymers. The basic aims of this project are to elucidate, manipulate, and utilise the unique chemical and physical properties of a class of biopolymers called the melanins. These materials are the only known solid state semiconducting biopolymers, and are non-toxic, biocompatible, and biodegradable. Their use as active components in biomimetic soft electonic, optoelectronic or photovoltaic devices, has not hitherto been demonstrated. It is anticipated that the k ....Photoactive Semiconducting Biopolymers. The basic aims of this project are to elucidate, manipulate, and utilise the unique chemical and physical properties of a class of biopolymers called the melanins. These materials are the only known solid state semiconducting biopolymers, and are non-toxic, biocompatible, and biodegradable. Their use as active components in biomimetic soft electonic, optoelectronic or photovoltaic devices, has not hitherto been demonstrated. It is anticipated that the key outcomes from the project will be a demonstration of biopolymer-based photoelectrochemical and solid-state p-i-n solar cells, and an improved understanding of the physics and chemistry of these important biological macromolecules.Read moreRead less
Naturally Photoactive Biopolymers. The basic aim of this project is to assess the viability of using semiconducting biopolymers from the melanin family of macromolecules in photoactive device based applications. In order to do this, key optical, structural, electronic, and photochemical properties will be assessed on thin films in the solid state. The melanins are the only known semiconducting biopolymers, and are non-toxic, biocompatible and biodegradable. Their use as ?active? materials in ....Naturally Photoactive Biopolymers. The basic aim of this project is to assess the viability of using semiconducting biopolymers from the melanin family of macromolecules in photoactive device based applications. In order to do this, key optical, structural, electronic, and photochemical properties will be assessed on thin films in the solid state. The melanins are the only known semiconducting biopolymers, and are non-toxic, biocompatible and biodegradable. Their use as ?active? materials in solid state or photo-electrochemical devices has never before been suggested. Specifically, these materials could be used as the light harvesting components in dye sensitised Gratzel cells, or, as the donor material in soft solid photovoltaic junctions. The melanins are also a key class of biomolecules (their involvement in skin cancers is well documented), and hence, any advancement in our understanding of their functions and properties could have biological importance.Read moreRead less
Design and Synthesis of Photoactive Peptides Based on Photosynthetic Reaction Centres. The aim of this proposal is to generate new and useful electron transfer components for biotechnological applications. We plan to design and synthesize artificial photoactive peptides inspired from natural photosynthetic reaction centres which capture the energy of light and convert it into usable forms of chemical energy. Our research will provide the ground work for the development of light-driven oxidation- ....Design and Synthesis of Photoactive Peptides Based on Photosynthetic Reaction Centres. The aim of this proposal is to generate new and useful electron transfer components for biotechnological applications. We plan to design and synthesize artificial photoactive peptides inspired from natural photosynthetic reaction centres which capture the energy of light and convert it into usable forms of chemical energy. Our research will provide the ground work for the development of light-driven oxidation-reduction catalysts that can be used in the production of clean fuels and chemical products.Read moreRead less
Comparative Biophysical Studies on Photosystem II of Higher Plants and Cyanobacteria. Photosystem II (PS-II) is one of two light trapping protein assemblies involved in the conversion of light into metabolic energy in all plants and algae. The manganese containing active site of PS-II is responsible for oxygen formation from water. The organisation and functioning of this centre and the detailed mechanism of photochemical energy conversion are not understood. This project will employ a combinati ....Comparative Biophysical Studies on Photosystem II of Higher Plants and Cyanobacteria. Photosystem II (PS-II) is one of two light trapping protein assemblies involved in the conversion of light into metabolic energy in all plants and algae. The manganese containing active site of PS-II is responsible for oxygen formation from water. The organisation and functioning of this centre and the detailed mechanism of photochemical energy conversion are not understood. This project will employ a combination of powerful biophysical techniques to probe the structure and mechanism of PS-II as a knowledge base for eventual genetic manipulation of plants and stategies for artificial photosynthesis.Read moreRead less
Biomolecular optoelectronic materials and devices. The melanins are the molecules in our skin, eyes and hair that provide colour and protection from the sun. In addition to being important bio-molecules, they have properties which make them useful for high tech applications especially in electronics and optoelectronics. Unfortunately, our current understanding of these fascinating materials is poor. In our project we aim to solve this limiting problem. We will develop new science to explain thei ....Biomolecular optoelectronic materials and devices. The melanins are the molecules in our skin, eyes and hair that provide colour and protection from the sun. In addition to being important bio-molecules, they have properties which make them useful for high tech applications especially in electronics and optoelectronics. Unfortunately, our current understanding of these fascinating materials is poor. In our project we aim to solve this limiting problem. We will develop new science to explain their behaviour, and use this knowledge to create bio-compatible hi-tech materials and devices. We anticipate significant benefits from the perspectives of basic science and utilisation of biomaterials for new green technologies.Read moreRead less