Portable three-dimensional ultra-low field MRI. This project aims to address low signal-to-noise ratio in ultra-low-field (ULF) MRI, using dynamic, mechanically-operated small permanent magnet arrays to generate magnetic fields needed for pre-polarisation and spatial encoding. Superconducting magnets make conventional MRI scanners too heavy and expensive for much of the world’s population. ULF MRI instruments offer image contrast mechanisms, are less costly and potentially portable, so can be us ....Portable three-dimensional ultra-low field MRI. This project aims to address low signal-to-noise ratio in ultra-low-field (ULF) MRI, using dynamic, mechanically-operated small permanent magnet arrays to generate magnetic fields needed for pre-polarisation and spatial encoding. Superconducting magnets make conventional MRI scanners too heavy and expensive for much of the world’s population. ULF MRI instruments offer image contrast mechanisms, are less costly and potentially portable, so can be used in unconventional situations. This project will design, construct and evaluate an instrument capable of three-dimensional 3D ULF-MRI. This technology is expected to be useable in field hospitals and emergency settings, and to benefit fields including magnetic refrigeration and remote sensing.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140100229
Funder
Australian Research Council
Funding Amount
$293,920.00
Summary
Ultra-low field magnetic resonance imaging with an array of localised magnetic field sensor . The aim of this project is to design and construct a multifunctional ultra-low magnetic field (ULF) magnetic resonance imaging (MRI) and nuclear magnetic resonance (NMR) instrument equipped with novel magnetic field sensors. This project is significant because it will deliver an instrument with enhanced sensitivity which is capable of obtaining non-invasive three-dimensional structural imaging of sample ....Ultra-low field magnetic resonance imaging with an array of localised magnetic field sensor . The aim of this project is to design and construct a multifunctional ultra-low magnetic field (ULF) magnetic resonance imaging (MRI) and nuclear magnetic resonance (NMR) instrument equipped with novel magnetic field sensors. This project is significant because it will deliver an instrument with enhanced sensitivity which is capable of obtaining non-invasive three-dimensional structural imaging of samples. This instrument will enable operation of highly sensitive ULF-MRI or ULF-NMR with regenerative energy sources and be a low-cost solution; reducing operation and maintenance costs as well as power consumption.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100843
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Regulating gene delivery with light. This project seeks to deliver the capacity to remotely deliver molecules into specific cells without the need for invasive or viral procedures. Individual genetic predisposition to disease forms a key part of personalised medicine that requires the accurate delivery of drugs or genes. This project aims to develop a new multimodality microscopy that can investigate and optimise light delivery of macromolecules into living cells at high specificity and across a ....Regulating gene delivery with light. This project seeks to deliver the capacity to remotely deliver molecules into specific cells without the need for invasive or viral procedures. Individual genetic predisposition to disease forms a key part of personalised medicine that requires the accurate delivery of drugs or genes. This project aims to develop a new multimodality microscopy that can investigate and optimise light delivery of macromolecules into living cells at high specificity and across a multitude of cells. The expected outcome of this project is a new form of in vivo molecular delivery system using light.Read moreRead less