Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100131
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
Biomaterials characterisation facility. The convergence of nanotechnology and biotechnology offers new opportunities to prepare nanoengineered materials for applications in biomedicine. The Biomaterials Characterisation Facility will provide equipment to characterise such nanoengineered materials to underpin advances in therapeutic drug delivery and tissue engineering.
Industrial Transformation Training Centres - Grant ID: IC180100024
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, internatio ....ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, international collaborations and a generation of industry-ready researchers critical for growing Australia’s industry. The advances in materials and savings in time for procedures will reduce costs.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989471
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Facility for innovation in structural biomaterials engineering. Biomaterials are used in a diverse range of environments that impact on the way that all Australians live. The Facility for Innovation in Structural Biomaterials Engineering will greatly assist researchers to undertake cross-disciplinary projects aimed at improving human health eg. smart materials that assist stem cell therapies for treating deafness and spinal cord injuries, as well the way we live eg. more durable building materia ....Facility for innovation in structural biomaterials engineering. Biomaterials are used in a diverse range of environments that impact on the way that all Australians live. The Facility for Innovation in Structural Biomaterials Engineering will greatly assist researchers to undertake cross-disciplinary projects aimed at improving human health eg. smart materials that assist stem cell therapies for treating deafness and spinal cord injuries, as well the way we live eg. more durable building materials for a sustainable national infrastructure. The facility will help Australia remain at the forefront of these high priority areas and see both individuals and industry benefit from advanced biomaterial products.Read moreRead less
Future neural electrodes: probing the electrical activity of nerves using 3D graphene networks. This research aims to develop a totally new type of neural electrode that will for the first time, allow reliable and long-term stimulation and recording. The approach incorporates graphene based biomaterials with tunable electrical and biological properties within supportive three-dimensional cellular microenvironments, greatly enhancing the electrical interactions between cells and the electrode. Th ....Future neural electrodes: probing the electrical activity of nerves using 3D graphene networks. This research aims to develop a totally new type of neural electrode that will for the first time, allow reliable and long-term stimulation and recording. The approach incorporates graphene based biomaterials with tunable electrical and biological properties within supportive three-dimensional cellular microenvironments, greatly enhancing the electrical interactions between cells and the electrode. The electrical properties of nerve cells will be probed using our three-dimensional graphene network, providing insight into the the brain-machine interface. This project is important as it directly addresses the inherent limitations of current electrode designs.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100057
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
A high-resolution X-ray microtomography system. This project aims to establish a Scanco microCT 50 high resolution X-Ray microtomography system, to non-destructively visualise and quantitatively characterise complex samples, including advanced composites, tissue engineering constructs, biological tissues, minerals and fossils. The non-destructive characterisation of these samples is critical to advance research. The versatile system offers high spatial resolution (down to 500 nm voxel size) and ....A high-resolution X-ray microtomography system. This project aims to establish a Scanco microCT 50 high resolution X-Ray microtomography system, to non-destructively visualise and quantitatively characterise complex samples, including advanced composites, tissue engineering constructs, biological tissues, minerals and fossils. The non-destructive characterisation of these samples is critical to advance research. The versatile system offers high spatial resolution (down to 500 nm voxel size) and large sample size (up to 100 mm diameter). The project will enable progress in advanced composites, additive bio-manufacturing, physiology of biological tissues and palaeontology which will benefit Australian science. Additionally, through commercialisation and the formation of new companies, the project could potentially result in economic and health benefits to the wider Australian population and economy.Read moreRead less
Harnessing the bioactivity of proteins and polypeptides: understanding and controlling adsorption processes to optimise linker free immobilisation. This project will use physical techniques and simulations to understand the interactions of biomolecules and plasma activated surfaces, allowing control of the biomolecule layer composition, orientation and conformation. This control, together with the ability of these surfaces to "lock-in" the optimised layer, will create a new generation of biodevi ....Harnessing the bioactivity of proteins and polypeptides: understanding and controlling adsorption processes to optimise linker free immobilisation. This project will use physical techniques and simulations to understand the interactions of biomolecules and plasma activated surfaces, allowing control of the biomolecule layer composition, orientation and conformation. This control, together with the ability of these surfaces to "lock-in" the optimised layer, will create a new generation of biodevices.Read moreRead less
Design and Fabrication of an Engineered Bone Graft System (EBGS) by combining a composite scaffold and growth factor delivery system. The lifetime risk for long bone fractures in Caucasians over the age of 50 is 17% for women and 6% for men. The prevalence of age-related fractures - and with it higher mortality rates due to complications following bone fractures - is therefore bound to increase over the coming decades. There is clearly a great need for therapies that take age-related changes in ....Design and Fabrication of an Engineered Bone Graft System (EBGS) by combining a composite scaffold and growth factor delivery system. The lifetime risk for long bone fractures in Caucasians over the age of 50 is 17% for women and 6% for men. The prevalence of age-related fractures - and with it higher mortality rates due to complications following bone fractures - is therefore bound to increase over the coming decades. There is clearly a great need for therapies that take age-related changes into consideration, in particular the diminishing capacity of bone to heal with age. In an effort to address the therapeutic challenges of providing bone grafts, we aim to mesh two leading-edge technologies to design and fabricate an Engineered Bone Graft System (EBGS) system. Read moreRead less
Tissue distraction: A novel approach to enhance tissue growth for soft tissue engineering purposes. This project will provide new tissues for the expanding field of regenerative medicine to treat numerous tissue defects and
1.Benefit the health & economic well being of Australian society by rapidly supplying organs and tissues.
2.Benefit the academic community by a multidisciplinary approach, involving several academic Institutions in the fields of surgery, tissue engineering, physiology, morph ....Tissue distraction: A novel approach to enhance tissue growth for soft tissue engineering purposes. This project will provide new tissues for the expanding field of regenerative medicine to treat numerous tissue defects and
1.Benefit the health & economic well being of Australian society by rapidly supplying organs and tissues.
2.Benefit the academic community by a multidisciplinary approach, involving several academic Institutions in the fields of surgery, tissue engineering, physiology, morphology, polymer chemistry & biomolecular engineering that will produce basic scientific data with a practical application. Post-graduate students and staff will train & gain significant knowledge in this area.
3. Benefit industry through new product development and IP. This project advances a platform technology with multiple applications.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668506
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
A Multi-Axis Biomaterials Testing Facility. Damage to bones and joints, due to injury or diseases such as osteoporosis and arthritis, is a major cause of disability and cost to the nation. Australia's ageing population contributes not only to an increasing incidence of such conditions, but also to more patients out-living implants such as replacement joints. In 2001-2, Australia spent over $800 million on joint replacement. Because over 11% of procedures are revisions of failed implants, even sm ....A Multi-Axis Biomaterials Testing Facility. Damage to bones and joints, due to injury or diseases such as osteoporosis and arthritis, is a major cause of disability and cost to the nation. Australia's ageing population contributes not only to an increasing incidence of such conditions, but also to more patients out-living implants such as replacement joints. In 2001-2, Australia spent over $800 million on joint replacement. Because over 11% of procedures are revisions of failed implants, even small improvements in implant life represent significant cost savings. By accurately simulating conditions within the body, this biomechanical testing facility will lead to new developments in implant designs and materials, in turn improving quality of life, productivity and treatment costs.Read moreRead less
Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplin ....Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplinary and international team will be valuable in establishing Australia's prominence in this field and training the next generation of young scientists and engineers. The technologies developed will be of great interest to a large number of research groups and companies worldwide and will assist with fostering international collaboration and placing Australia at the forefront of this emerging field.Read moreRead less