Development of Advanced Wear Debris Analysis Techniques for Osteoarthritis Study. Wear and tear of joints is the common cause of osteoarthritis, costing $19.25 billion/year. With this cost on the increase, and no cure to date, comes a need to develop effective methods for its diagnosis. This study will provide new knowledge on osteoarthritis progression by allowing strategic use of national health resources. A fuzzy expert system, to be developed utilising the diagnostic/prognostic techniques of ....Development of Advanced Wear Debris Analysis Techniques for Osteoarthritis Study. Wear and tear of joints is the common cause of osteoarthritis, costing $19.25 billion/year. With this cost on the increase, and no cure to date, comes a need to develop effective methods for its diagnosis. This study will provide new knowledge on osteoarthritis progression by allowing strategic use of national health resources. A fuzzy expert system, to be developed utilising the diagnostic/prognostic techniques of this study will significantly reduce cost and time. The project will contribute to the National Strategy by helping older Australians; the major group of osteoarthritis sufferers, to retain their health, independence and productivity.Read moreRead less
Development of new methods to measure in vivo properties of human body tissues. This project will develop new methods of noninvasively measuring the viscoelastic properties of soft tissues in live humans, using a novel magnetic resonance elastography technique. These methods will be applied to study the operation of the human muscle-tendon system, differences in neck muscle properties with age and gender and to measure the properties of the human brain, kidney and liver in vivo. These techniques ....Development of new methods to measure in vivo properties of human body tissues. This project will develop new methods of noninvasively measuring the viscoelastic properties of soft tissues in live humans, using a novel magnetic resonance elastography technique. These methods will be applied to study the operation of the human muscle-tendon system, differences in neck muscle properties with age and gender and to measure the properties of the human brain, kidney and liver in vivo. These techniques may be useful in diagnosing soft tissue disease or injury which are currently difficult to detect using standard imaging techniques. It will also explain how the muscle-tendon unit moves during normal motion in live humans.Read moreRead less
Novel methods for detecting changes in soft tissue microstructure and biomechanical properties using multi-modality MR imaging. This project will lead to novel methods for studying the internal structure of the soft tissues of the body, such as muscles and brain tissue, and how this is affected by mechanical loading and disease states. The project will thoroughly validate these new methods. This will not only provide new techniques for research use, but lead to improved diagnostic techniques in ....Novel methods for detecting changes in soft tissue microstructure and biomechanical properties using multi-modality MR imaging. This project will lead to novel methods for studying the internal structure of the soft tissues of the body, such as muscles and brain tissue, and how this is affected by mechanical loading and disease states. The project will thoroughly validate these new methods. This will not only provide new techniques for research use, but lead to improved diagnostic techniques in the future.Read moreRead less