Computational haemodynamics system for prediction of risk of rupture of cerebral aneurysms. Every year about 2000 Australians suffer a ruptured aneurysm in the brain and some 750 of these die within 4 weeks. Since there is an increase in the detection of unruptured aneurysms, especially in healthy young people, there is an urgent need to be able to decide which lead to rupture and to provide suitable treatment options. This project, which will provide markedly improved means of patient-specific ....Computational haemodynamics system for prediction of risk of rupture of cerebral aneurysms. Every year about 2000 Australians suffer a ruptured aneurysm in the brain and some 750 of these die within 4 weeks. Since there is an increase in the detection of unruptured aneurysms, especially in healthy young people, there is an urgent need to be able to decide which lead to rupture and to provide suitable treatment options. This project, which will provide markedly improved means of patient-specific risk determination for aneurysm rupture, will have significant impact in reducing associated costs on the national health burden due to cerebral hemorrhage and stroke, on community productivity and disability and on more efficient targeting of expensive and dangerous brain surgery.Read moreRead less
Developing a Hemodynamic Model for Improving Clinical Treatment of Vascular Diseases. Stroke caused by vascular diseases is the second greatest single killer, which is taking away thousands of lives and costing billions every year in Australia. Improving the existing clinical treatments of these diseases is thus of utmost urgency. This project is targeted to developing a reliable Hemodynamic model through comprehensive experimental validation approach. It will not only foster a more in-depth res ....Developing a Hemodynamic Model for Improving Clinical Treatment of Vascular Diseases. Stroke caused by vascular diseases is the second greatest single killer, which is taking away thousands of lives and costing billions every year in Australia. Improving the existing clinical treatments of these diseases is thus of utmost urgency. This project is targeted to developing a reliable Hemodynamic model through comprehensive experimental validation approach. It will not only foster a more in-depth research of vascular diseases but also provide a virtual forecasting tool for physicians or surgeons to develop guidance on diagnosis and therapeutic planning of clinical treatment, which brings great socio-economic benefit to the health of the Australian community.Read moreRead less
Three-dimensional Simulation of Trabecular Bone Remodelling. Nearly 2 million Australians currently suffer from osteoporosis. Statistics indicate that 25% of Australian women and 17% of men will develop an osteoporotic fracture. The cost of osteoporosis is $7.4 billion per annum; the numbers of affected individuals and costs are expected to continue increasing. Clearly, improvements to osteoporosis diagnosis, fracture risk assessment, and effective treatments are still urgently needed. The p ....Three-dimensional Simulation of Trabecular Bone Remodelling. Nearly 2 million Australians currently suffer from osteoporosis. Statistics indicate that 25% of Australian women and 17% of men will develop an osteoporotic fracture. The cost of osteoporosis is $7.4 billion per annum; the numbers of affected individuals and costs are expected to continue increasing. Clearly, improvements to osteoporosis diagnosis, fracture risk assessment, and effective treatments are still urgently needed. The proposed project aims to create a tool for understanding the mechanisms of bone loss and predicting the effects of osteoporosis therapies. It represents a solid contribution to the knowledge base necessary for advancing osteoporosis research and ultimately reducing the incidence of osteoporotic fracture.Read moreRead less