Industrial Transformation Training Centres - Grant ID: IC180100024
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, internatio ....ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, international collaborations and a generation of industry-ready researchers critical for growing Australia’s industry. The advances in materials and savings in time for procedures will reduce costs.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100011
Funder
Australian Research Council
Funding Amount
$900,000.00
Summary
Integrated Multimodal System for Multiplexed Imaging of Signal Transduction. This project will introduce a unique microscopy platform and associated technologies into the Australian research environment that will enable researchers to redefine our understanding of molecular signal transduction. The instrumentation will enable the multidimensional imaging of live cells with unprecendented speed and sensitivity. The featured imaging modalities will enable the integration of distinct biological, ....Integrated Multimodal System for Multiplexed Imaging of Signal Transduction. This project will introduce a unique microscopy platform and associated technologies into the Australian research environment that will enable researchers to redefine our understanding of molecular signal transduction. The instrumentation will enable the multidimensional imaging of live cells with unprecendented speed and sensitivity. The featured imaging modalities will enable the integration of distinct biological, biochemical and chemical probes with a focus on minimizing phototoxicity. Expected outcomes include new fundamental knowledge on molecular signal transduction and cell heterogeneity; development of novel probes and methodologies and the development of new and existing interdisciplinary research collaborations. Read moreRead less
Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most importa ....Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most important mechano-sensor implicated in cell adhesion, migration, growth and survival. Specifically, it integrates nationally unique cutting-edge techniques including single-molecule force probe, microparticle image velocimetry, microfluidics and molecular dynamics simulation, super resolution and 3D volumetric imaging modalities.Read moreRead less
Pedal and motor cycle helmet performance study. Cycling is a form of recreation and transport. Both pedal and motor cyclists are exposed to risks of head and neck injury. These injuries occur in young people and can have substantial health and economic impacts on the individuals and society. It is believed that injury rates can be reduced and an active lifestyle encouraged by improving helmet performance and understanding factors that lead to non-use. As helmet use is mandatory it is importa ....Pedal and motor cycle helmet performance study. Cycling is a form of recreation and transport. Both pedal and motor cyclists are exposed to risks of head and neck injury. These injuries occur in young people and can have substantial health and economic impacts on the individuals and society. It is believed that injury rates can be reduced and an active lifestyle encouraged by improving helmet performance and understanding factors that lead to non-use. As helmet use is mandatory it is important that Australians are provided with optimal helmets. The specification of product standards is also relevant for international trade agreements. Read moreRead less
Haemodynamic investigation of flow diverter stents for the treatment of intracranial aneurysms. This project will explore the engineering of a flow diverter, an endovascular device for the treatment of brain aneurysms. The project will determine the optimal design of new types of flow diverters, which in turn could improve the effectiveness of treatments, thus reducing the associated costs of cerebral haemorrhage and stroke.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100001
Funder
Australian Research Council
Funding Amount
$875,000.00
Summary
A 3-photon imaging system for deep live imaging. This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology. This project will capitalise on advanced laser, microscope and adaptive optics technologies with the expected out ....A 3-photon imaging system for deep live imaging. This project aims to establish Australia’s first 3-photon microscope system with adaptive optics for deep intravital imaging. This advanced imaging system will enable researchers to investigate the biology of cells and tissue structures in a wide range of organs and engineered tissues, to a degree not possible with existing technology. This project will capitalise on advanced laser, microscope and adaptive optics technologies with the expected outcomes to include the generation of new knowledge of major biological systems, including the immune system and the nervous system. This will provide significant benefits to fundamental interdisciplinary research into immunology, infectious disease, neuroscience, mechanobiology and engineering.Read moreRead less
Rail Safety And Reliability: A Human Factors/Ergonomics Approach. Recent rail crashes have focussed rail operators and the public on issues of rail safety and reliabilty. The project is a major initiative that will assist the development of safer and more reliable rail operations through the application of human factors and ergonomics methods to the design of train control and management devices and systems.