Industrial Transformation Training Centres - Grant ID: IC180100024
Funder
Australian Research Council
Funding Amount
$4,000,000.00
Summary
ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, internatio ....ARC Training Centre for Medical Implant Technologies. The ARC Training Centre for Medical Implant Technologies aims to train a new generation of interdisciplinary engineers and to transform the orthopaedic and maxillofacial implant industry in Australia. In collaboration with industry, universities and hospitals, the Centre will build a dynamic training environment for interdisciplinary engineers to develop and evaluate personalised implants and surgeries. It will create new networks, international collaborations and a generation of industry-ready researchers critical for growing Australia’s industry. The advances in materials and savings in time for procedures will reduce costs.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100011
Funder
Australian Research Council
Funding Amount
$900,000.00
Summary
Integrated Multimodal System for Multiplexed Imaging of Signal Transduction. This project will introduce a unique microscopy platform and associated technologies into the Australian research environment that will enable researchers to redefine our understanding of molecular signal transduction. The instrumentation will enable the multidimensional imaging of live cells with unprecendented speed and sensitivity. The featured imaging modalities will enable the integration of distinct biological, ....Integrated Multimodal System for Multiplexed Imaging of Signal Transduction. This project will introduce a unique microscopy platform and associated technologies into the Australian research environment that will enable researchers to redefine our understanding of molecular signal transduction. The instrumentation will enable the multidimensional imaging of live cells with unprecendented speed and sensitivity. The featured imaging modalities will enable the integration of distinct biological, biochemical and chemical probes with a focus on minimizing phototoxicity. Expected outcomes include new fundamental knowledge on molecular signal transduction and cell heterogeneity; development of novel probes and methodologies and the development of new and existing interdisciplinary research collaborations. Read moreRead less
Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most importa ....Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most important mechano-sensor implicated in cell adhesion, migration, growth and survival. Specifically, it integrates nationally unique cutting-edge techniques including single-molecule force probe, microparticle image velocimetry, microfluidics and molecular dynamics simulation, super resolution and 3D volumetric imaging modalities.Read moreRead less
Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplin ....Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplinary and international team will be valuable in establishing Australia's prominence in this field and training the next generation of young scientists and engineers. The technologies developed will be of great interest to a large number of research groups and companies worldwide and will assist with fostering international collaboration and placing Australia at the forefront of this emerging field.Read moreRead less
Pedal and motor cycle helmet performance study. Cycling is a form of recreation and transport. Both pedal and motor cyclists are exposed to risks of head and neck injury. These injuries occur in young people and can have substantial health and economic impacts on the individuals and society. It is believed that injury rates can be reduced and an active lifestyle encouraged by improving helmet performance and understanding factors that lead to non-use. As helmet use is mandatory it is importa ....Pedal and motor cycle helmet performance study. Cycling is a form of recreation and transport. Both pedal and motor cyclists are exposed to risks of head and neck injury. These injuries occur in young people and can have substantial health and economic impacts on the individuals and society. It is believed that injury rates can be reduced and an active lifestyle encouraged by improving helmet performance and understanding factors that lead to non-use. As helmet use is mandatory it is important that Australians are provided with optimal helmets. The specification of product standards is also relevant for international trade agreements. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100095
Funder
Australian Research Council
Funding Amount
$620,000.00
Summary
High-resolution X-ray micro computed tomography supporting West Australian geo-, physical and biological science. An X-ray micro computed tomography facility will provide West Australian researchers with much needed access to cutting-edge instrumentation for high-resolution three-dimensional imaging. This facility will support major research programs in key disciplines, including minerals and mining, energy, medical and biological sciences.
Aerodynamic interaction of bluff bodies with applications to sports aerodynamics. Numerical modelling and experiments will be combined by this project to characterise the flow and reduce drag on a set of objects in the wake of another object. The Olympic pursuit cycling team is a typical application, with small improvements leading to major competitiveness gains. Findings will also apply to Paralympic team sports, and potentially transportation.
Theoretical and experimental studies on magnetoelectroelastic bone remodelling process. The project combines biotechnology and material science which will have national economic, social and environment impact. It can benefit industry by providing knowledge that help scientists understand remodeling under coupled fields and is used to develop bone replacement. By better understanding remodeling due to multi-field loading, we can assist scientists in aeronautical industry in developing countermeas ....Theoretical and experimental studies on magnetoelectroelastic bone remodelling process. The project combines biotechnology and material science which will have national economic, social and environment impact. It can benefit industry by providing knowledge that help scientists understand remodeling under coupled fields and is used to develop bone replacement. By better understanding remodeling due to multi-field loading, we can assist scientists in aeronautical industry in developing countermeasures that reduce or eliminate bone loss resulting from long-duration space flight. It can provide knowledge that can be used to explore underlying mechanisms controlling bone remodeling and self-repair in gaining insight into debilitating diseases such as osteoporosis, to develop high-performance prosthetics for medical injury healing.Read moreRead less
Haemodynamic investigation of flow diverter stents for the treatment of intracranial aneurysms. This project will explore the engineering of a flow diverter, an endovascular device for the treatment of brain aneurysms. The project will determine the optimal design of new types of flow diverters, which in turn could improve the effectiveness of treatments, thus reducing the associated costs of cerebral haemorrhage and stroke.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100166
Funder
Australian Research Council
Funding Amount
$637,800.00
Summary
Four-dimensional coherent imaging velocimetry facility for fluid mechanics research. This project aims to enhance understanding of multi-scale fluid flows in engineering, geophysics and biomedicine by delivering a facility for high temporal and spatial resolution, three-dimensional velocity measurements. The four-dimensional, coherent imaging velocimetry facility for fluid mechanics research is aimed at addressing limitations of commercially available imaging systems. It is expected to provide ....Four-dimensional coherent imaging velocimetry facility for fluid mechanics research. This project aims to enhance understanding of multi-scale fluid flows in engineering, geophysics and biomedicine by delivering a facility for high temporal and spatial resolution, three-dimensional velocity measurements. The four-dimensional, coherent imaging velocimetry facility for fluid mechanics research is aimed at addressing limitations of commercially available imaging systems. It is expected to provide unprecedented measurement capabilities with significant benefit to the design, control and modelling of complex fluid flows found in many areas. Applications include the jets used for heating, cooling, mixing, and drug delivery in engineering and pharmacy to the kinematics of sperm and micro-organisms in bio-medicine, and wave-particle flows in geo-physics.Read moreRead less