New Biomimetic Nanostructured Coatings for Hip Implants. Over 30,000 hip implants operations take place in Australia each year, due largely to a significant and growing proportion of the population suffering from conditions such as osteoporosis. The coating on the implants, required to cause good bone ingrowth and adhesion between bone and implant, is far from perfect. We propose to spray coatings which mimic the structure of bone, and thus offer improved mechanical properties such as appropriat ....New Biomimetic Nanostructured Coatings for Hip Implants. Over 30,000 hip implants operations take place in Australia each year, due largely to a significant and growing proportion of the population suffering from conditions such as osteoporosis. The coating on the implants, required to cause good bone ingrowth and adhesion between bone and implant, is far from perfect. We propose to spray coatings which mimic the structure of bone, and thus offer improved mechanical properties such as appropriate rigidity and toughness, and stimulate better bone growth at the interface. In this way the implant should be much longer lasting and the need for undesirable revision surgery reduced. The processing technique proposed could also be a useful platform coating technology in a number of other industries.Read moreRead less
Using nanostructured biomaterials and stem cells to repair spinal cord injuries. There is currently no effective cure for spinal cord injuries and the consequences to the patient are devastating. Spinal cord injuries affects limb, bowel, bladder and sexual function, and many people with these injuries strugle to maintain their independence. Because people can live for many years after spinal cord damage, the financial and social costs are immense, as many are dependent on the help of others for ....Using nanostructured biomaterials and stem cells to repair spinal cord injuries. There is currently no effective cure for spinal cord injuries and the consequences to the patient are devastating. Spinal cord injuries affects limb, bowel, bladder and sexual function, and many people with these injuries strugle to maintain their independence. Because people can live for many years after spinal cord damage, the financial and social costs are immense, as many are dependent on the help of others for their survival. This proposal tackles this urgent problem by applying advanced nanostructured materials with stem cells, to assist the body in the repair of the spinal cord following injury. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453963
Funder
Australian Research Council
Funding Amount
$546,352.00
Summary
An integrated nanoscale fabrication, manipulation and characterisation facility. The fabrication of ordered structures at the nanometre scale is essential if the aspirations of nanotechnology are to be achieved. Understanding the fundamental nanoscience controlling the fabrication and operation of such devices is vital. The combination of instruments requested for this project will allow the construction of arrays of nanoparticles, their precise characterisation and the direct measurement of i ....An integrated nanoscale fabrication, manipulation and characterisation facility. The fabrication of ordered structures at the nanometre scale is essential if the aspirations of nanotechnology are to be achieved. Understanding the fundamental nanoscience controlling the fabrication and operation of such devices is vital. The combination of instruments requested for this project will allow the construction of arrays of nanoparticles, their precise characterisation and the direct measurement of interpartice and intermolecular forces at the pN level. Parallel computational chemistry and state of the art experiments will lead to the optimised design of nanostructures that will be applied in diverse areas, including mineral processing, biosensors, photonics, magnetic storage and catalysis.Read moreRead less