Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100139
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
A Hot Isostatic Press (HIP) for aerospace and biomedical component processing. This facility will provide a hot isostatic press of sufficiently large capacity to maximise production efficiencies in aerospace and biomedical applications through net shape manufacturing. The facility will be able to process small components or prototypes which will behave in a manner similar to larger scale components.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100057
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
A high-resolution X-ray microtomography system. This project aims to establish a Scanco microCT 50 high resolution X-Ray microtomography system, to non-destructively visualise and quantitatively characterise complex samples, including advanced composites, tissue engineering constructs, biological tissues, minerals and fossils. The non-destructive characterisation of these samples is critical to advance research. The versatile system offers high spatial resolution (down to 500 nm voxel size) and ....A high-resolution X-ray microtomography system. This project aims to establish a Scanco microCT 50 high resolution X-Ray microtomography system, to non-destructively visualise and quantitatively characterise complex samples, including advanced composites, tissue engineering constructs, biological tissues, minerals and fossils. The non-destructive characterisation of these samples is critical to advance research. The versatile system offers high spatial resolution (down to 500 nm voxel size) and large sample size (up to 100 mm diameter). The project will enable progress in advanced composites, additive bio-manufacturing, physiology of biological tissues and palaeontology which will benefit Australian science. Additionally, through commercialisation and the formation of new companies, the project could potentially result in economic and health benefits to the wider Australian population and economy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100028
Funder
Australian Research Council
Funding Amount
$720,000.00
Summary
Ultra-high resolution and advanced analytical scanning electron microscope facility. This scanning electron microscope facility will form an essential part of characterising a broad range of material types, from nanometre sized particles through to cells and their interactions.
Design and Fabrication of an Engineered Bone Graft System (EBGS) by combining a composite scaffold and growth factor delivery system. The lifetime risk for long bone fractures in Caucasians over the age of 50 is 17% for women and 6% for men. The prevalence of age-related fractures - and with it higher mortality rates due to complications following bone fractures - is therefore bound to increase over the coming decades. There is clearly a great need for therapies that take age-related changes in ....Design and Fabrication of an Engineered Bone Graft System (EBGS) by combining a composite scaffold and growth factor delivery system. The lifetime risk for long bone fractures in Caucasians over the age of 50 is 17% for women and 6% for men. The prevalence of age-related fractures - and with it higher mortality rates due to complications following bone fractures - is therefore bound to increase over the coming decades. There is clearly a great need for therapies that take age-related changes into consideration, in particular the diminishing capacity of bone to heal with age. In an effort to address the therapeutic challenges of providing bone grafts, we aim to mesh two leading-edge technologies to design and fabricate an Engineered Bone Graft System (EBGS) system. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668506
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
A Multi-Axis Biomaterials Testing Facility. Damage to bones and joints, due to injury or diseases such as osteoporosis and arthritis, is a major cause of disability and cost to the nation. Australia's ageing population contributes not only to an increasing incidence of such conditions, but also to more patients out-living implants such as replacement joints. In 2001-2, Australia spent over $800 million on joint replacement. Because over 11% of procedures are revisions of failed implants, even sm ....A Multi-Axis Biomaterials Testing Facility. Damage to bones and joints, due to injury or diseases such as osteoporosis and arthritis, is a major cause of disability and cost to the nation. Australia's ageing population contributes not only to an increasing incidence of such conditions, but also to more patients out-living implants such as replacement joints. In 2001-2, Australia spent over $800 million on joint replacement. Because over 11% of procedures are revisions of failed implants, even small improvements in implant life represent significant cost savings. By accurately simulating conditions within the body, this biomechanical testing facility will lead to new developments in implant designs and materials, in turn improving quality of life, productivity and treatment costs.Read moreRead less
Development and validation of virtual epithelial cancer models using an integrated modelling and experimental three-dimensional approach. The mathematical and experimental modelling of the human prostate and ovary applying quantitative bioengineering concepts will lead to virtual cancer models. This project aims to validate these multi-scale models to delineate biological and pathological avenues in healthy and disease tissue and improve prevention and treatment of prostate and ovarian cancer.
Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplin ....Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplinary and international team will be valuable in establishing Australia's prominence in this field and training the next generation of young scientists and engineers. The technologies developed will be of great interest to a large number of research groups and companies worldwide and will assist with fostering international collaboration and placing Australia at the forefront of this emerging field.Read moreRead less
Convergence of biomaterials and immunology: a technology platform for delayed burst release of vaccines. A large challenge in vaccination, particularly in wildlife such as for the growing problem of Chlamydia in koalas, is to provide the necessary booster shots. This project will develop implants that will be inserted under the skin at the time of the first shot, and will spontaneously burst later to release the booster shot to provide protection.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100012
Funder
Australian Research Council
Funding Amount
$890,000.00
Summary
Dual Column-Focused Ion Beam/Scanning Electron Microscope facility for Queensland. Dual column focused ion beam/scanning electron microscope facility: This facility will precisely cut specimens and surfaces that can be imaged in a variety of ways, including crystallographic and elemental space, of particular use for physical scientists, as well as biological specimens. This instrument will provide information at resolutions between optical and transmission electron microscopy, images that will ....Dual Column-Focused Ion Beam/Scanning Electron Microscope facility for Queensland. Dual column focused ion beam/scanning electron microscope facility: This facility will precisely cut specimens and surfaces that can be imaged in a variety of ways, including crystallographic and elemental space, of particular use for physical scientists, as well as biological specimens. This instrument will provide information at resolutions between optical and transmission electron microscopy, images that will effectively provide the biologist with the ability to develop the complete correlative picture of organelles and cells. The instrument will also provide a much needed resource for researchers across disciplines such as physics, chemistry, biology, geology and engineering.Read moreRead less
Frontiers in bone and joint regeneration. Key outcomes of this project will deliver innovative strategies for scaffold-based bone and cartilage engineering whilst contributing to the education of a new generation of bioengineers, biomaterial scientists and tissue engineers with a strong international profile.