Neural circuit control of effort under stress . This Project aims to investigate how the ‘decision’ to persist in exerting effort to obtain a reward is encoded in the the brain and affected by stress. This work will generate new knowledge on the neural mechanisms through which stress modifies neural activity to control decision making processes underpinning adaptive behaviours essential for survival. The expected outcomes of this work include enhanced capacity at the interface of behavioural a ....Neural circuit control of effort under stress . This Project aims to investigate how the ‘decision’ to persist in exerting effort to obtain a reward is encoded in the the brain and affected by stress. This work will generate new knowledge on the neural mechanisms through which stress modifies neural activity to control decision making processes underpinning adaptive behaviours essential for survival. The expected outcomes of this work include enhanced capacity at the interface of behavioural and computational neuroscience, that will in turn provide significant benefits through greater insight into brain functions essential for survival, with long ranging implications for performance optimisation and brain-inspired computing. Read moreRead less
Neurochemical predictors of cognition and the impact of brain stimulation. This project aims to determine how neurochemical equilibrium between excitation and inhibition (E/I balance), across the brain, is associated with executive function and how this balance is influenced by non-invasive brain stimulation. Brain stimulation shows immense promise for enhancing executive function in applied settings, but the neurochemical basis for this is unknown. Using advanced imaging and stimulation techniq ....Neurochemical predictors of cognition and the impact of brain stimulation. This project aims to determine how neurochemical equilibrium between excitation and inhibition (E/I balance), across the brain, is associated with executive function and how this balance is influenced by non-invasive brain stimulation. Brain stimulation shows immense promise for enhancing executive function in applied settings, but the neurochemical basis for this is unknown. Using advanced imaging and stimulation techniques, the project aims to provide comprehensive insights into the causal relationship between stimulation, E/I balance and executive function. Outcomes and benefits include identifying neurochemical characteristics that determine stimulation efficacy and informing the design of protocols for applied use.Read moreRead less