Revealing novel mechanisms conferring evolution of resistance to glufosinate and glyphosate in Eleusine indica. Glyphosate and its alternative glufosinate are the most important herbicides in world agriculture. The world’s first cases of glufosinate resistance in Eleusine indica have been recently reported. The aims of the proposed research is to identify the currently unknown biochemical and molecular mechanisms conferring glufosinate resistance, to unravel the novel molecular mechanism endowin ....Revealing novel mechanisms conferring evolution of resistance to glufosinate and glyphosate in Eleusine indica. Glyphosate and its alternative glufosinate are the most important herbicides in world agriculture. The world’s first cases of glufosinate resistance in Eleusine indica have been recently reported. The aims of the proposed research is to identify the currently unknown biochemical and molecular mechanisms conferring glufosinate resistance, to unravel the novel molecular mechanism endowing very high level glyphosate resistance, and to elucidate the evolutionary trajectory of glyphosate resistance in E. indica. This will advance our current knowledge and understanding of resistance evolution and have impact on resistance management.Read moreRead less
Harnessing genetic diversity for complex traits. Genetic diversity underpins crop improvement but has become increasingly narrow in our major crops. Strategies exist for mobilising simple traits (e.g. disease resistance) from wild accessions or landraces into cultivars, but there are no effective approaches for introducing complex traits, including stress tolerance or components of yield. Using barley as an important crop and a genetic model, the project aims to address this problem by applying ....Harnessing genetic diversity for complex traits. Genetic diversity underpins crop improvement but has become increasingly narrow in our major crops. Strategies exist for mobilising simple traits (e.g. disease resistance) from wild accessions or landraces into cultivars, but there are no effective approaches for introducing complex traits, including stress tolerance or components of yield. Using barley as an important crop and a genetic model, the project aims to address this problem by applying a novel approach; partial redomestication of wild accessions by introgressing genes required for modern farming, then evaluating the resulting partially adapted germplasm in hybrids with elite cultivars. The project expects to generate new and diverse germplasm pools for breeding.Read moreRead less
Molecular switches and genetic consequences of grain retention in cereals. Grain retention at maturity was key for crop domestication and laid the basis for farming. Wheat and barley have evolved a novel mechanism for ensuring grain retention and, although the genes are known, the mechanisms for action are not. Grain dispersal in the wild relatives involves highly targeted changes in the walls of a small number of cells. This project will explore how the two identified genes control this proces ....Molecular switches and genetic consequences of grain retention in cereals. Grain retention at maturity was key for crop domestication and laid the basis for farming. Wheat and barley have evolved a novel mechanism for ensuring grain retention and, although the genes are known, the mechanisms for action are not. Grain dispersal in the wild relatives involves highly targeted changes in the walls of a small number of cells. This project will explore how the two identified genes control this process and clarify their mode of action. The genes ensuring grain retention have been so critical for domestication that the region surrounding them has become genetically fixed. The project will assess the implication of fixation on genetic diversity and develop options to bring novel variation into breeding programs.Read moreRead less