Synthesis and Characterisation of Encoded Hybrid Polymer/Gold Nanoparticles for Application in Bioassays. Bioassays are the cornerstone of in vitro diagnostic and biomedical research. This proposal will significantly contribute to these areas, by targeting an emerging technology that is crucial for their future development. The hybrid nanoparticles described in this project have the potential to replace conventional detection strategies that are currently used for bioassays. In doing so, they sh ....Synthesis and Characterisation of Encoded Hybrid Polymer/Gold Nanoparticles for Application in Bioassays. Bioassays are the cornerstone of in vitro diagnostic and biomedical research. This proposal will significantly contribute to these areas, by targeting an emerging technology that is crucial for their future development. The hybrid nanoparticles described in this project have the potential to replace conventional detection strategies that are currently used for bioassays. In doing so, they should provide significant advantages over conventional detection strategies. These advantages include increased sample throughput and conservation of biological samples, which makes possible the acceleration of patient diagnosis and drug discovery. Read moreRead less
Plant cell wall - aluminium interactions: a role in aluminium stress. Soil acidity, resulting in Al toxicity, affects production on circa 50% of Australia's intensively used agricultural land, resulting in 8.5 times more foregone agricultural income than dryland salinity (National Land and Water Resources Audit, 2001). Often, remediation with lime is not possible or affordable. By understanding Al reactions with cell wall components, we aim to identify root parameters related to Al resistance by ....Plant cell wall - aluminium interactions: a role in aluminium stress. Soil acidity, resulting in Al toxicity, affects production on circa 50% of Australia's intensively used agricultural land, resulting in 8.5 times more foregone agricultural income than dryland salinity (National Land and Water Resources Audit, 2001). Often, remediation with lime is not possible or affordable. By understanding Al reactions with cell wall components, we aim to identify root parameters related to Al resistance by plants. These parameters will be useful as selection markers to identify and breed Al-tolerant crop genotypes. This, in turn, will improve yields and farm profitability, allowing farmers to use lime to prevent further acidification. This increases sustainability of cropping operations on the 50 Mha with acid soils.Read moreRead less
Modifying and Improving Porous Sol-Gel Materials for Water Purification. XeroCoat is commercialising nanotechnology research out of UQ's Physics department. XeroCoat has received much local and international interest in its signature product 'XeroCoat'. The company is rapidly expanding and has established new research facilities with production facilities to be set-up. This will result in high technology, employment growth for Australia. Links with Flinders could see expansion into SA. The c ....Modifying and Improving Porous Sol-Gel Materials for Water Purification. XeroCoat is commercialising nanotechnology research out of UQ's Physics department. XeroCoat has received much local and international interest in its signature product 'XeroCoat'. The company is rapidly expanding and has established new research facilities with production facilities to be set-up. This will result in high technology, employment growth for Australia. Links with Flinders could see expansion into SA. The company operates in 'Sol-Gel' nanotechnology, which has huge global, academic and commercial interest. However in Australia this technology has only been serviced by Flinders, ANSTO and ANSTO's spin-out company Ceramisphere. The project will help to build a new Australian high tech industry in sol-gel nanotechnology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0237908
Funder
Australian Research Council
Funding Amount
$637,000.00
Summary
Mass Spectrometry Instrumentation for Therapeutic Lead Discovery. Drug discovery is reliant on the application of basic research and advanced technologies to obtain solutions to human suffering caused by diseases. This application seeks funding to support the installation of state-of-the-art mass spectrometry instrumentation at Griffith University and the University of Melbourne. The requested instrumentation will enhance high quality collaborative research programs in drug discovery and eradica ....Mass Spectrometry Instrumentation for Therapeutic Lead Discovery. Drug discovery is reliant on the application of basic research and advanced technologies to obtain solutions to human suffering caused by diseases. This application seeks funding to support the installation of state-of-the-art mass spectrometry instrumentation at Griffith University and the University of Melbourne. The requested instrumentation will enhance high quality collaborative research programs in drug discovery and eradicate significant deficiencies in research infrastructure at both institutions. Access to state-of-the-art mass spectrometry instrumentation will markedly improve our international competitiveness across a broad range of biological and chemical science disciplines.Read moreRead less