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Energy Conversion and Signal Transduction in Nanomechanical Systems. Miniaturization of materials and electronic devices is an important technological goal. In order to make smaller working devices,we need to understand how to create molecular scale devices such as valves, switches, pumps and motors. This Fellowship will explore ways to make smaller, portable devices that can be used for personal health monitoring,environmental sensing and the detection of disease and pathogens.
Rethinking Mental Health Laws: An Integrated Approach. Mental health is one of the Commonwealth Government's national health priority areas. This research program will ensure the best possible outcomes for the Government's five-year action plan for better mental health services by developing model legal frameworks that will help shape the way in which individuals with mental illnesses can access the highest attainable standard of mental health care. Through interdisciplinary collaboration and th ....Rethinking Mental Health Laws: An Integrated Approach. Mental health is one of the Commonwealth Government's national health priority areas. This research program will ensure the best possible outcomes for the Government's five-year action plan for better mental health services by developing model legal frameworks that will help shape the way in which individuals with mental illnesses can access the highest attainable standard of mental health care. Through interdisciplinary collaboration and through developing model frameworks for both civil commitment and sentencing laws, this program will enable Australia to set the international agenda as to how countries can best respond to the mental health needs of their citizens.Read moreRead less
The New Dimensions of the Quantum Universe. This Fellowship will help build and strengthen significant world-class research capacity at the frontier of fundamental science. More students will be motivated to pursue careers in science, increasing the number of talented, world-class science graduates in Australia. It will forge strong research links both locally and internationally so as to enhance existing networks and create new ones. It will greatly enhance Australia's standing in particle phys ....The New Dimensions of the Quantum Universe. This Fellowship will help build and strengthen significant world-class research capacity at the frontier of fundamental science. More students will be motivated to pursue careers in science, increasing the number of talented, world-class science graduates in Australia. It will forge strong research links both locally and internationally so as to enhance existing networks and create new ones. It will greatly enhance Australia's standing in particle physics, the epitome of Big Science, and garner new respect from one of the world's most influential scientific communities. Having this kind of world-class research in Australia, will also help foster public education and advance the public understanding of fundamental science.
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Structural neurobiology - developing a new capability in Australia to treat mental illness. Mental illness encompasses a multitude of devastating conditions that present a major burden to the Australian economy. In this project powerful tools for determining the three-dimensional shapes and functions of proteins will be utilised to gain new knowledge about the molecular bases of various mental illnesses. The project will involve extensive use of the Australian Synchrotron Facility that is due to ....Structural neurobiology - developing a new capability in Australia to treat mental illness. Mental illness encompasses a multitude of devastating conditions that present a major burden to the Australian economy. In this project powerful tools for determining the three-dimensional shapes and functions of proteins will be utilised to gain new knowledge about the molecular bases of various mental illnesses. The project will involve extensive use of the Australian Synchrotron Facility that is due to open in 2007. This knowledge gained from the project will be used to develop new therapeutic drugs to ameliorate or combat mental diseases in partnership with the Australian Biotechnology Industry.Read moreRead less
Using Law To Improve Population Health and the Quality of Health Care Services. There are huge gaps in our understanding of how legal rules and processes impact population health and the quality of health care services in Australia. This research program will begin to fill those gaps by addressing topical issues such as medical negligence litigation, the coroner's role in injury prevention, and the use of medical science in the courtroom. The findings will be useful to government policymakers, ....Using Law To Improve Population Health and the Quality of Health Care Services. There are huge gaps in our understanding of how legal rules and processes impact population health and the quality of health care services in Australia. This research program will begin to fill those gaps by addressing topical issues such as medical negligence litigation, the coroner's role in injury prevention, and the use of medical science in the courtroom. The findings will be useful to government policymakers, regulators, and judges, as well as professionals working in both the legal and health care fields. But most importantly, the findings will serve patients by helping to shape strategies and reforms that enable Australia's health care system to deliver services that are safer, of higher quality, fairer, and more efficient.Read moreRead less
Molecular control of apoptosis and protein homeostasis. A million cells are produced every second by cell division. At the same time a million cells commit suicide by a process called apoptosis. When cells fail to die when they should they can develop into cancers. In heart attacks, stroke and neurodegenerative diseases, many cells appear to activate their self destruct mechanism to die unnecessarily. Drugs that can cause cancer cells to kill themselves, or drugs that prevent cells dying when th ....Molecular control of apoptosis and protein homeostasis. A million cells are produced every second by cell division. At the same time a million cells commit suicide by a process called apoptosis. When cells fail to die when they should they can develop into cancers. In heart attacks, stroke and neurodegenerative diseases, many cells appear to activate their self destruct mechanism to die unnecessarily. Drugs that can cause cancer cells to kill themselves, or drugs that prevent cells dying when they shouldn't, would make a major impact on many important diseases. Understanding the molecular mechanisms of cell death is the first step towards developing these drugs.Read moreRead less
Wall Turbulence Drag: Physical Mechanisms and Practicable Control Strategies. The proposed research will build on Australia's well-established strengths in Fluid Mechanics, and aim to establish within Australia world-leading expertise in turbulence control and drag reduction technology. This will have direct benefits to the Australian economy through Tourism (among other industries) by reducing the adverse impact of rising fuel prices on long-distance air travel, on which Australia is disproport ....Wall Turbulence Drag: Physical Mechanisms and Practicable Control Strategies. The proposed research will build on Australia's well-established strengths in Fluid Mechanics, and aim to establish within Australia world-leading expertise in turbulence control and drag reduction technology. This will have direct benefits to the Australian economy through Tourism (among other industries) by reducing the adverse impact of rising fuel prices on long-distance air travel, on which Australia is disproportionately reliant due to its geographic isolation. Efficient turbulence control strategies will also lead to improved combustion processes, resulting in not only better fuel efficiency but also reduced CO2 and pollutant emissions.Read moreRead less
Evaluating the adaptive potential of organisms to respond to environmental change. The program utilizes technological advances to develop a gene inventory for climatic change adaptation, using, as model system, the vinegar fly from divergent climates along eastern Australia. The inventory will result in new methods for monitoring climatic change impact on populations, and for testing adaptive potential of organisms from threatened habitats. A key hypothesis is that these organisms have restricte ....Evaluating the adaptive potential of organisms to respond to environmental change. The program utilizes technological advances to develop a gene inventory for climatic change adaptation, using, as model system, the vinegar fly from divergent climates along eastern Australia. The inventory will result in new methods for monitoring climatic change impact on populations, and for testing adaptive potential of organisms from threatened habitats. A key hypothesis is that these organisms have restricted genetic options to counter environmental change, increasing extinction risk. The program investigates genetic adaptation to pollutants in midges, a key group for monitoring water health. By assessing evolutionary potential and DNA species markers, biological signatures of aquatic pollutants should result.Read moreRead less
Improving understanding of climate change and its impacts in Australia through detection and attribution of climate change. This research will quantify the contribution to Australian regional climate change due to greenhouse gases, which will assist policymakers in reaching decisions about policies on emission reductions or adaptation to greenhouse climate change. Improved estimates of uncertainties in future regional climate changes due to increasing greenhouse gases will allow better quantifi ....Improving understanding of climate change and its impacts in Australia through detection and attribution of climate change. This research will quantify the contribution to Australian regional climate change due to greenhouse gases, which will assist policymakers in reaching decisions about policies on emission reductions or adaptation to greenhouse climate change. Improved estimates of uncertainties in future regional climate changes due to increasing greenhouse gases will allow better quantification of their likely impacts, estimation of the costs or maximising any benefits from regional climate changes. Through collaboration with the Bureau of Meteorology and CSIRO, this research enhances Australia's capabilities in diagnostic analysis of climate variability and change, and aids the development and evaluation of new Australian climate models. Read moreRead less
The Role of Metals in the Biology of the Ageing Brain. Aims
1.To advance basic understanding of the interactions between cellular proteins and biologically important metals
2. To learn how these interactions change as the organism ages
3. To study the pathological results of aberrant metal biology using animal and cellular models of major age-dependent neurodegenerative disease.
In a rapidly ageing society, neurodegenerative disorders such as Alzheimer's and Parkinson's diseases will presen ....The Role of Metals in the Biology of the Ageing Brain. Aims
1.To advance basic understanding of the interactions between cellular proteins and biologically important metals
2. To learn how these interactions change as the organism ages
3. To study the pathological results of aberrant metal biology using animal and cellular models of major age-dependent neurodegenerative disease.
In a rapidly ageing society, neurodegenerative disorders such as Alzheimer's and Parkinson's diseases will present a medical and economic challenge demanding novel and powerful science. This research will lead both to deeper understanding of the basic mechanisms underlying such disorders and to tools for designing new and effective treatments.
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