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Deep-sea coral ocean-climate records of the last glacial and recent eras. The project aims to predict the ocean carbon dioxide sink’s long-term capacity and future trajectories of global warming and increasing carbon dioxide. This project will use geochemical proxies encoded in the skeletons of deep-sea corals in the Perth Canyon, Tasman seas, and Antarctica, in the heart of the ocean-climate system, to reveal continuous long-term records of environmental change at annual-decadal resolution for ....Deep-sea coral ocean-climate records of the last glacial and recent eras. The project aims to predict the ocean carbon dioxide sink’s long-term capacity and future trajectories of global warming and increasing carbon dioxide. This project will use geochemical proxies encoded in the skeletons of deep-sea corals in the Perth Canyon, Tasman seas, and Antarctica, in the heart of the ocean-climate system, to reveal continuous long-term records of environmental change at annual-decadal resolution for our recent past (hundreds to thousands of years) and the Last Glacial Maximum. These records are expected to provide a more accurate understanding of Earth’s long-term responses to anthropogenic carbon dioxide emissions and global warming.Read moreRead less
Intelligent nanoparticles: Interactive tools to decode brain activity. This project aims to use nanoparticles and integrated nanoparticle devices to unravel causal relationships between molecular events and high-level brain activity. These devices, capable of real-time sensing and adaptive responses, could expose previously unmeasurable cellular events and establish their physiological effects. This is expected to reveal the complex dynamics in the living brain and advance neuroscience and analy ....Intelligent nanoparticles: Interactive tools to decode brain activity. This project aims to use nanoparticles and integrated nanoparticle devices to unravel causal relationships between molecular events and high-level brain activity. These devices, capable of real-time sensing and adaptive responses, could expose previously unmeasurable cellular events and establish their physiological effects. This is expected to reveal the complex dynamics in the living brain and advance neuroscience and analytical chemistry.Read moreRead less
Integrating the humanities into Antarctic studies. Antarctica is currently taking a key role in climate change debate. It is vital that we understand the cultural meanings we attach to the continent and the attitudes we bring to it. This project aims to create a rounded understanding of the Antarctic by integrating the humanities into what is currently a science-dominated research area.
Enhancing our understanding of metallochemistry in neurobiology with modern electron paramagnetic resonance (EPR) spectroscopy. Many neurological diseases involve protein accumulation that appears causally linked to abnormal levels of metal ions in the brain. This project will use a special technique called electron paramagnetic resonance to uncover how these metals interact with specific proteins at the molecular level and how drug treatments can modify these interactions.
Moral frontiers: When the needs of humans and nonhumans collide. Decision making about resources is not simply based on human needs alone. Issues relating to animal rights, biodiversity, and environmental protection weigh heavily in these debates. These issues are receiving increased attention at a time when the human (over)population of the planet is already placing pressure on scare resources, creating conflict between the needs of humans and non-humans. It is along our moral frontiers where t ....Moral frontiers: When the needs of humans and nonhumans collide. Decision making about resources is not simply based on human needs alone. Issues relating to animal rights, biodiversity, and environmental protection weigh heavily in these debates. These issues are receiving increased attention at a time when the human (over)population of the planet is already placing pressure on scare resources, creating conflict between the needs of humans and non-humans. It is along our moral frontiers where these conflicts will erupt and the rights and needs of humans and non-humans alike are given merit or discarded. This project will examine the psychological processes involved in extending moral concern to non-humans and the benefits and costs of this extended morality for the satisfaction of human needs.Read moreRead less
Philanthropy, celebrity and governance in the People's Republic of China. The project is the first major study of the new phenomenon of celebrity philanthropy and its governance in present-day China. It will provide knowledge of government and philanthropic responses to some of the problems associated with unequal development in China and increase Australians' capacity to engage effectively with a rapidly changing China.
Fundamentals and applications of dynamic interfacial forces in soft matter. The proposed program will make an internationally significant contribution to the fundamental understanding of soft matter on the nanoscale. This has a direct impact upon processes that are key to a wide range of Australian industries ranging from the manufacture of functional foods to minerals recovery to pharmaceutical formulation, where innovative solutions can substantially improve productivity, increase export pote ....Fundamentals and applications of dynamic interfacial forces in soft matter. The proposed program will make an internationally significant contribution to the fundamental understanding of soft matter on the nanoscale. This has a direct impact upon processes that are key to a wide range of Australian industries ranging from the manufacture of functional foods to minerals recovery to pharmaceutical formulation, where innovative solutions can substantially improve productivity, increase export potential and reduce environmental impact. The outcomes of this work, in the form of high impact papers and conference presentations, will build and enhance Australia's reputation as a world leader in nanotechnology and colloid science. Read moreRead less
Lithium-air battery: a green energy source for the sustainable future. Electrification of vehicles and the implementation of smart electric grids can dramatically reduce greenhouse gas emissions and realise sustainable development. Lithium-air batteries have the highest energy density among all battery systems and are therefore a promising power source for electric vehicles and stationary energy storage.
Breaching membrane barriers. This project will endeavour to develop novel molecular transporters to deliver macromolecules inside cells or microorganisms. Cell membranes are barriers to macromolecules. The ability to cross these barriers and deliver biological macromolecules into cells represents a major achievement with endless opportunities to modulate pathways and to introduce biomarkers, therapeutics and research tools. The project’s novel platform technology would be based on stable cyclic ....Breaching membrane barriers. This project will endeavour to develop novel molecular transporters to deliver macromolecules inside cells or microorganisms. Cell membranes are barriers to macromolecules. The ability to cross these barriers and deliver biological macromolecules into cells represents a major achievement with endless opportunities to modulate pathways and to introduce biomarkers, therapeutics and research tools. The project’s novel platform technology would be based on stable cyclic peptides to deliver genes, proteins, probes or biomarkers into distinct cell types that can monitor or modulate specific pathways and be translated into new knowledge and specific industrial applications.Read moreRead less
New materials for manipulating intracellular communication. This project aims to identify new techniques for incorporating cell-signalling triggers into macromolecules, therefore enabling the development of next-generation stimuli-responsive nanoparticles that can emit signalling molecules on demand. Harnessing nanomaterials to stimulate specific sub-cellular processes is a neglected area in nanotechnology research. These nanoparticles could potentially be used to deliver signalling molecules fo ....New materials for manipulating intracellular communication. This project aims to identify new techniques for incorporating cell-signalling triggers into macromolecules, therefore enabling the development of next-generation stimuli-responsive nanoparticles that can emit signalling molecules on demand. Harnessing nanomaterials to stimulate specific sub-cellular processes is a neglected area in nanotechnology research. These nanoparticles could potentially be used to deliver signalling molecules for agricultural, pharmaceutical and veterinary applications. The project is expected to develop a new suite of materials that could ultimately be used to improve the yield of important commercial crops, or revitalise the use of medicines limited by their poor side effect profile.Read moreRead less