Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most importa ....Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most important mechano-sensor implicated in cell adhesion, migration, growth and survival. Specifically, it integrates nationally unique cutting-edge techniques including single-molecule force probe, microparticle image velocimetry, microfluidics and molecular dynamics simulation, super resolution and 3D volumetric imaging modalities.Read moreRead less
Atomic sensors for dark matter, rotation and magnetic fields. This project aims to develop ultra-high-performance sensors. The research will explore new methods for using the magnetic and optical properties of atomic gases to enable multi-parameter sensing without crosstalk between measurements. It is expected that techniques will be developed to allow simultaneous sensing of rotation and magnetic fields using devices that are compact, ultra-precise and energy efficient. It is also anticipated t ....Atomic sensors for dark matter, rotation and magnetic fields. This project aims to develop ultra-high-performance sensors. The research will explore new methods for using the magnetic and optical properties of atomic gases to enable multi-parameter sensing without crosstalk between measurements. It is expected that techniques will be developed to allow simultaneous sensing of rotation and magnetic fields using devices that are compact, ultra-precise and energy efficient. It is also anticipated that these new atomic sensors will support a global network looking for dark matter, which although never seen, is thought to make up 85% of the mass of the universe. The outcomes are expected to benefit medical science, geo-exploration, high-tech manufacturing, navigation and our understanding of the universe.Read moreRead less
Resonator-enhanced quantum levitation of macroscopic systems. This project aims to develop advanced technologies to optically levitate macroscopic (millimetre-sized) objects and nanoscopic (atomically thin) materials. Levitation platforms built by the investigatory team are based on the resonantly amplified radiation pressure of laser beams. This new type of optical levitation can provide ultimate isolation of the systems from external noise, making them extremely responsive to subtle environmen ....Resonator-enhanced quantum levitation of macroscopic systems. This project aims to develop advanced technologies to optically levitate macroscopic (millimetre-sized) objects and nanoscopic (atomically thin) materials. Levitation platforms built by the investigatory team are based on the resonantly amplified radiation pressure of laser beams. This new type of optical levitation can provide ultimate isolation of the systems from external noise, making them extremely responsive to subtle environmental changes. These platforms could be turned into sharp instruments for measuring metrological variables of interest and probing new physics. Quantum optical techniques could be developed to optimise the sensitivity of levitated systems to levels that allow the exploration of quantum and gravitational physics.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100035
Funder
Australian Research Council
Funding Amount
$4,958,927.00
Summary
ARC Training Centre for Hyphenated Analytical Separation Technologies . The toughest analytical science challenges typically require advanced analytical technologies to acquire the desired solutions. In the field of separation science this inevitably involves hyphenated separation technologies, specifically the combination of chromatography and mass spectrometry. Advancing this technology to its full capability requires the collaborative strength of academic, industry and end-user partnerships, ....ARC Training Centre for Hyphenated Analytical Separation Technologies . The toughest analytical science challenges typically require advanced analytical technologies to acquire the desired solutions. In the field of separation science this inevitably involves hyphenated separation technologies, specifically the combination of chromatography and mass spectrometry. Advancing this technology to its full capability requires the collaborative strength of academic, industry and end-user partnerships, providing the materials and inspiration for young researchers to apply novel hyphenated methods to complex environmental and industrial systems. This Centre will deliver fundamental developments in hyphenated technologies, new analytical capability, and applied outcomes across multiple end-user groups and interests. Read moreRead less
Role of water in earth and planetary evolution. This project aims to understand the role of water in the building of our solar system, Mars and Earth. Surprisingly little is known about key issues surrounding the origin of water and its subsequent recycling on Earth. This project will use new techniques for measuring low abundances of water along with oxygen isotopes, to measure water abundances and oxygen isotopes in meteorites and terrestrial rocks to establish how water was delivered to Earth ....Role of water in earth and planetary evolution. This project aims to understand the role of water in the building of our solar system, Mars and Earth. Surprisingly little is known about key issues surrounding the origin of water and its subsequent recycling on Earth. This project will use new techniques for measuring low abundances of water along with oxygen isotopes, to measure water abundances and oxygen isotopes in meteorites and terrestrial rocks to establish how water was delivered to Earth and to understand how water is geologically recycled. This is expected to have direct bearing on where and how Earth's water originated, how water is retained in mantle and crustal minerals and it will have broad implications for understanding volcanic hazards and formation of ore deposits. This will lead to a new capability for combined water and oxygen isotope analysis in Australian geoscience leading to technological development and commercialisation of instrumentation.Read moreRead less
ARC Centre of Excellence for All Sky Astrophysics in 3 Dimensions. This Centre aims to answer fundamental questions in astrophysics including the origin of matter and the periodic table of elements, and the origin of ionisation in the Universe. It intends to use Australian three-dimensional technology to transform our understanding of the Universe. It will unify world-leading Australian optical and radio surveys with theoretical simulations and new e-Science techniques for Peta-scale data sets. ....ARC Centre of Excellence for All Sky Astrophysics in 3 Dimensions. This Centre aims to answer fundamental questions in astrophysics including the origin of matter and the periodic table of elements, and the origin of ionisation in the Universe. It intends to use Australian three-dimensional technology to transform our understanding of the Universe. It will unify world-leading Australian optical and radio surveys with theoretical simulations and new e-Science techniques for Peta-scale data sets. The Centre will also nurture young scientific leaders and make high-school students interested in STEM sciences through education and outreach programmes. It is expected the research will propel Australia to the forefront of astronomical research for the coming decade while capitalising on innovative instrumentation.Read moreRead less
A new in-situ structural measurement capability during nanoindentation. A new in-situ structural measurement capability during nanoindentation. This project aims to develop an in-situ Raman capability to obtain dynamic structural and mechanical behaviour of materials as a function of pressure during nanoindentation; and apply the new capability to directly monitor phase changes in silicon and germanium under pressure and correlate them with the simultaneous electrical responses. Anticipated outc ....A new in-situ structural measurement capability during nanoindentation. A new in-situ structural measurement capability during nanoindentation. This project aims to develop an in-situ Raman capability to obtain dynamic structural and mechanical behaviour of materials as a function of pressure during nanoindentation; and apply the new capability to directly monitor phase changes in silicon and germanium under pressure and correlate them with the simultaneous electrical responses. Anticipated outcomes are new instrumentation to directly probe the pressure-temperature phase diagram, and measure electrical properties of novel end phases in these semiconductors.Read moreRead less
ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reac ....ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reactions and how higher brain function emerges from networks of neurons. By building a diverse, multidisciplinary, and industry-engaged ecosystem, the Centre means to develop our future leaders at the interface of quantum science and biology and drive Australian innovation across manufacturing, energy, agriculture, health, and national security.Read moreRead less
Terahertz lasers in the fight against illicit substances. This project aims to investigate the application of cutting-edge terahertz laser technology with new spectroscopic methods, for detection of illicit substances. Using a collaborative approach, the project aims to bring together expertise in laser physics, spectroscopy, law enforcement and instrumentation, and seeks to develop new sources and detection protocols which will offer new capabilities to law enforcement, aiding in detection and ....Terahertz lasers in the fight against illicit substances. This project aims to investigate the application of cutting-edge terahertz laser technology with new spectroscopic methods, for detection of illicit substances. Using a collaborative approach, the project aims to bring together expertise in laser physics, spectroscopy, law enforcement and instrumentation, and seeks to develop new sources and detection protocols which will offer new capabilities to law enforcement, aiding in detection and identification protocols for illicit substances.Read moreRead less
X-ray Ghost Imaging and Tomography. This project aims to achieve safer, faster, and cheaper 3D X-ray imaging through a technique known as ghost imaging. X-ray imaging provides valuable information about internal structures, however, X-rays are carcinogenic and exposure (or dose) should be limited. Ghost imaging is an unconventional technique developed with visible light that has many potential benefits over conventional imaging. This research group are world leaders in ghost imaging and expect t ....X-ray Ghost Imaging and Tomography. This project aims to achieve safer, faster, and cheaper 3D X-ray imaging through a technique known as ghost imaging. X-ray imaging provides valuable information about internal structures, however, X-rays are carcinogenic and exposure (or dose) should be limited. Ghost imaging is an unconventional technique developed with visible light that has many potential benefits over conventional imaging. This research group are world leaders in ghost imaging and expect to develop software and hardware techniques to realise its potential and extend it to ghost tomography. The focus of this project is on reducing cancer risk in medical imaging, and allowing real-time quality control for 3D printing in safety-critical industries such as aerospace.Read moreRead less