Closing the data gap: High throughput screening of nanoparticle toxicity. The nanotechnology sector is experiencing an exponential growth period with over 100 products containing manufactured nanoparticles entering the market every year. Ensuring growth of the sector needs to be balanced against the imperative of protecting both human and environmental safety. This project aims to develop new methodological and conceptual avenues to close the gap between innovation in nanotechnology and risk ass ....Closing the data gap: High throughput screening of nanoparticle toxicity. The nanotechnology sector is experiencing an exponential growth period with over 100 products containing manufactured nanoparticles entering the market every year. Ensuring growth of the sector needs to be balanced against the imperative of protecting both human and environmental safety. This project aims to develop new methodological and conceptual avenues to close the gap between innovation in nanotechnology and risk assessment. This is intended to be achieved by developing and validating high-throughput in vitro toxicity screening platforms for manufactured nanoparticles. The approach is based on advanced lab-on-a-chip microfluidic technologies. The predictive power of the platform will be refined and optimised via ex-vivo and in-vivo models.Read moreRead less
Patchy colloidosomes at interfaces: correlation of particle surface heterogeneity, wettability, and chemical activity at the nanoscale. The surfaces of natural mineral particles are made up of spots with such different chemical and physical properties. The complexity makes it hard to predict their behaviour. This project will provide insights into how the 'patchy' nature of particle surfaces affects their behaviour in processes such as flotation separation and bio-fuel production.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989068
Funder
Australian Research Council
Funding Amount
$637,120.00
Summary
Equipment for Metastable Induced Electron Spectroscopy: surface analysis with excellent surface sensitivity. One of the major research strengths of Australia is surface science as it is important for both fundamental and industry related research. In many cases it is crucial to investigate the outermost layer of a material or mineral. Metastable Induced Electron Spectroscopy is an ideal technique as it is sensitive exclusively to the outermost layer of a broad range of samples. The information g ....Equipment for Metastable Induced Electron Spectroscopy: surface analysis with excellent surface sensitivity. One of the major research strengths of Australia is surface science as it is important for both fundamental and industry related research. In many cases it is crucial to investigate the outermost layer of a material or mineral. Metastable Induced Electron Spectroscopy is an ideal technique as it is sensitive exclusively to the outermost layer of a broad range of samples. The information gained is not accessible by any other method. The proposed equipment will be the first of this type in Australia and will complement existing surface science facilities. The project will enhance Australia's position in surface science internationally and a large number of projects will benefit from access to the equipment.Read moreRead less
Nanotribology and Nanorheometry: A Fundamental Study of the Dynamic Interactions of Particles and Surfaces at the Molecular Level. Friction and deformation occur from the mutual motion and interaction of microscopic particles and surfaces. This research aims to develop new theories and measurement techniques for these non-equilibrium phenomena by combining mathematical analysis and numerical computations with dynamic force measurement, surface modification, and surface characterisation on nanom ....Nanotribology and Nanorheometry: A Fundamental Study of the Dynamic Interactions of Particles and Surfaces at the Molecular Level. Friction and deformation occur from the mutual motion and interaction of microscopic particles and surfaces. This research aims to develop new theories and measurement techniques for these non-equilibrium phenomena by combining mathematical analysis and numerical computations with dynamic force measurement, surface modification, and surface characterisation on nanometre and molecular length scales. These insights and data will be critically important in designing low-friction surfaces that save energy and wear, in developing nanoscopic probes for the mechanical and structural properties of soft polymeric and bio-materials, and in making high performance coatings that control adhesion and particle aggregation in technologically advanced applications.Read moreRead less
A nanoengineered solution to drug delivery in bone. This project presents an exciting new approach of applying nanotechnology to bone research. By combining our expertise in nanoengineering of new materials, mathematical modelling and bone biology, this project will result in a well-characterised model for drug delivery into bone and lead to a new therapeutic approach for treating bone diseases.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100146
Funder
Australian Research Council
Funding Amount
$800,000.00
Summary
Ultra high vacuum scanning probe microscope facility. Ultra high-vacuum scanning tunneling microscopy underpins advances in the understanding of novel materials for electronics, engineering and medical applications, including thin-films, nanostructures, advanced semiconductors, nanostructured (organic or inorganic) conductors, and nanoscale interfaces (heteronanostructures). It is a core technique underpinning the new Superscience agenda in Future Technologies. A number of present and future re ....Ultra high vacuum scanning probe microscope facility. Ultra high-vacuum scanning tunneling microscopy underpins advances in the understanding of novel materials for electronics, engineering and medical applications, including thin-films, nanostructures, advanced semiconductors, nanostructured (organic or inorganic) conductors, and nanoscale interfaces (heteronanostructures). It is a core technique underpinning the new Superscience agenda in Future Technologies. A number of present and future research fields will benefit from the presence of this instrument, which will enhance Australia's competitiveness in nanotechnology research and development. Training of PhD and graduate students in this area is essential to exploit the potentiality of nanotechnology for the future benefit of Australia.Read moreRead less
Development of advanced lithium ion battery and battery management system for electric /hybrid electric vehicle applications. This project represents a significant scientific and economic development for Australia as it aims to create advanced, high performing, energy storage devices with a focus on safety, that will provide enormous benefits for the environment. An added advantage will be the establishment of local and national expertise in the area of electrochemical energy storage systems, th ....Development of advanced lithium ion battery and battery management system for electric /hybrid electric vehicle applications. This project represents a significant scientific and economic development for Australia as it aims to create advanced, high performing, energy storage devices with a focus on safety, that will provide enormous benefits for the environment. An added advantage will be the establishment of local and national expertise in the area of electrochemical energy storage systems, that will place Australia at the forefront of lithium ion battery research and development. Flow-on benefits will also be created for Australian organizations involved in the manufacturing of electric vehicles and portable devices.Read moreRead less
Aerodynamic enhancement of the capture of fine particle emissions and gaseous pollutants by sorbents. Fine particulate emissions alone, and just within Australia's four largest cities, are estimated to be responsible for some 1600 deaths annually, and are a leading cause of asthma and other lung disease. Hence the economic and social benefits of greatly reducing fine particulate emissions is enormous. Similar benefits can be expected to arise from the enhanced capture of SOx, NOx and heavy metal ....Aerodynamic enhancement of the capture of fine particle emissions and gaseous pollutants by sorbents. Fine particulate emissions alone, and just within Australia's four largest cities, are estimated to be responsible for some 1600 deaths annually, and are a leading cause of asthma and other lung disease. Hence the economic and social benefits of greatly reducing fine particulate emissions is enormous. Similar benefits can be expected to arise from the enhanced capture of SOx, NOx and heavy metals. Many of these pollutants also contribute to the greenhouse effect, so the international exploitation of the technology will also help to mitigate climate change. Should suitable sorbents be developed for CO2 capture, the technology will also enhance carbon capture and storage.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560705
Funder
Australian Research Council
Funding Amount
$825,000.00
Summary
Advanced Deformation Simulation Laboratory. For Australia to maintain its position as a world leader in the science of metals processing it must have the capability for state-of-the-art physical simulation. The present proposal is for the purchase and installation of two leading edge simulation tools: a high rate/short inter-pass hot deformation simulator and a hot equal channel angular extrusion press. Advanced hot deformation simulation is required for the development and optimisation of "fast ....Advanced Deformation Simulation Laboratory. For Australia to maintain its position as a world leader in the science of metals processing it must have the capability for state-of-the-art physical simulation. The present proposal is for the purchase and installation of two leading edge simulation tools: a high rate/short inter-pass hot deformation simulator and a hot equal channel angular extrusion press. Advanced hot deformation simulation is required for the development and optimisation of "fast" industrial processes and for understanding the complex microstructural reactions associated with them. High temperature extrusion is required for the development of ultra-fine and nano-grained light metals.Read moreRead less