Development of Novel Pesticidal Agents. We have discovered a family of naturally occurring plant proteins called the cyclotides that have potent insecticidal activity against Helicoverpa species, one of the major pests on cotton and corn in Australia and world wide. Preliminary evidence has shown that they also have activity against major pests to livestock in Australia, including sheep blowflies. To develop these proteins as potential pesticidal agents it is necessary to understand the struct ....Development of Novel Pesticidal Agents. We have discovered a family of naturally occurring plant proteins called the cyclotides that have potent insecticidal activity against Helicoverpa species, one of the major pests on cotton and corn in Australia and world wide. Preliminary evidence has shown that they also have activity against major pests to livestock in Australia, including sheep blowflies. To develop these proteins as potential pesticidal agents it is necessary to understand the structural basis for their activity. We will do this by chemically synthesising peptides with selected residues mutated to determine their effects on activity.Read moreRead less
ARC Centre of Excellence for Robotic Vision. Robots are vital to Australia's future prosperity in the face of high relative wages, low or decreasing productivity, and impending labour shortages. However the work and workplaces of our most important industries are unstructured and changeable and current robots are challenged by their inability to quickly, safely and reliably "see" and "understand" what is around them. The Centre's research will create the fundamental science and technologies th ....ARC Centre of Excellence for Robotic Vision. Robots are vital to Australia's future prosperity in the face of high relative wages, low or decreasing productivity, and impending labour shortages. However the work and workplaces of our most important industries are unstructured and changeable and current robots are challenged by their inability to quickly, safely and reliably "see" and "understand" what is around them. The Centre's research will create the fundamental science and technologies that will allow robots to see as we do, and overcome the last barrier to the ubiquitous deployment of robots into society for the benefit of all.Read moreRead less
ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environme ....ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environments. EII will address 3 tightly coupled research themes: Ability to interoperate across existing heterogenous platforms & applications; Efficient processing of very large data sets; Technology adoption & impact. Generic results will be applicable to e-science and large business information systems installations.Read moreRead less
Special Research Initiatives - Grant ID: SR0354575
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Earth and Ocean Informatics and Technology Network (EON-ITnet). Sustainable resource exploration and mining onshore, as well as marine planning, exploration, and defence depend on effective cross-disciplinary investigation, sharing of expertise and technologies for integration and computational analysis of multidimensional data spaces. EON-ITNET will cross-fertilise the use of artificial intelligence, advanced computing and smart information sharing for management, analysis, visualisation and me ....Earth and Ocean Informatics and Technology Network (EON-ITnet). Sustainable resource exploration and mining onshore, as well as marine planning, exploration, and defence depend on effective cross-disciplinary investigation, sharing of expertise and technologies for integration and computational analysis of multidimensional data spaces. EON-ITNET will cross-fertilise the use of artificial intelligence, advanced computing and smart information sharing for management, analysis, visualisation and metadata modelling between these traditionally separate research groups, with the outcome of improving research efficiency and lowering costs. EON-ITNET will form an alliance with the Caltech-based GeoFramework, which is advancing a novel object-oriented data analysis environment, binding community software for Earth visualisation and simulation to 4D data bases.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100181
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
Strengthening merit-based access and support at the new National Computing Infrastructure petascale supercomputing facility. World-leading high-performance computing is fundamental to Australia's international research success. This facility will provide access to the new National Computational Infrastructure facility by world-leading researchers from six research universities, and sustain ground-breaking work in an increasingly competitive environment.
Special Research Initiatives - Grant ID: SR0354880
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Building trust in Australia's infrastructure: dealing with scientific, technological, business, policy and legal issues in information security. Australia is faced with the challenge of engendering trust in, and protecting, the information systems vital to the economic and social development of the nation. This initiative will produce a national direction for research, development and educational activities in information security with particular emphasis on the protection of the national intere ....Building trust in Australia's infrastructure: dealing with scientific, technological, business, policy and legal issues in information security. Australia is faced with the challenge of engendering trust in, and protecting, the information systems vital to the economic and social development of the nation. This initiative will produce a national direction for research, development and educational activities in information security with particular emphasis on the protection of the national interest. It will do so by bringing together for the first time, academic, government and business people from a vast array of backgrounds, and whose interests lie across a spectrum of commercial, legal, policy and research outcomes.Read moreRead less
Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, ....Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, unprecedented in scope and resolution. Outcomes include an open access database to quantify and visualise intra-urban air pollution and human exposure and develop air quality maps and smoke pollution management tools. It is expected to advance the evidence-based management of air as a resource, increasing economic prosperity and enhancing human health and quality of life.Read moreRead less
ARC Centre of Excellence for Core to Crust Fluid Systems. Water is essential for human existence, indeed for life's beginning. The circulation of water between the surface and the deep interior lubricates the internal dynamics that keep Earth geologically alive; it is crucial to most Earth systems, including the evolution of the hydrospher/atmosphere/biosphere, and the development of giant ore deposits. However, the origin, abundance, speciation and movements of fluids inside Earth are largely u ....ARC Centre of Excellence for Core to Crust Fluid Systems. Water is essential for human existence, indeed for life's beginning. The circulation of water between the surface and the deep interior lubricates the internal dynamics that keep Earth geologically alive; it is crucial to most Earth systems, including the evolution of the hydrospher/atmosphere/biosphere, and the development of giant ore deposits. However, the origin, abundance, speciation and movements of fluids inside Earth are largely unknown, and represent key issues in modern geoscience. This CoE will integrate previously disparate fields - geology, tectonics, geochemistry, petrophysics, geophysics and dynamic modelling - to understand the workings of Earth's deep plumbing system.Read moreRead less
Revolutionising protection against air pollution. This interdisciplinary project aims to develop a personalised air pollution exposure monitoring system, leveraging the ubiquitousness and advancements in mobile phone technology and state of the art miniaturisation of monitoring sensors, data transmission and analysis. Airborne pollution is one of the top contemporary risks faced by humans; however, at present individuals have no way to recognise that they are at risk or need to protect themselve ....Revolutionising protection against air pollution. This interdisciplinary project aims to develop a personalised air pollution exposure monitoring system, leveraging the ubiquitousness and advancements in mobile phone technology and state of the art miniaturisation of monitoring sensors, data transmission and analysis. Airborne pollution is one of the top contemporary risks faced by humans; however, at present individuals have no way to recognise that they are at risk or need to protect themselves. It is expected that the outcome will empower individuals to control and minimise their own exposures. This is expected to lead to significant national socioeconomic benefits and bring global advancement in acquiring and utilising environmental information.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150100652
Funder
Australian Research Council
Funding Amount
$345,000.00
Summary
Regulation of organ size and stem cell hierarchy in the developing kidney. Transient stem/progenitor cell populations play essential roles in establishing organ systems. The balance between self-renewal and differentiation in the nephron progenitor population plays a major, but poorly understood, role in regulating kidney development. Factors produced by undifferentiated progenitors promote organ expansion, whereas differentiation of these cells builds functional capacity. What is not clear is h ....Regulation of organ size and stem cell hierarchy in the developing kidney. Transient stem/progenitor cell populations play essential roles in establishing organ systems. The balance between self-renewal and differentiation in the nephron progenitor population plays a major, but poorly understood, role in regulating kidney development. Factors produced by undifferentiated progenitors promote organ expansion, whereas differentiation of these cells builds functional capacity. What is not clear is how the balance between self-renewal and differentiation is regulated in these cells, nor how the control of this fate decision impacts on optimal organ development. This project aims to dissect the molecular identity, regulation, and influence of this stem cell population on kidney development.Read moreRead less