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The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which ....The Epigenetics of Sex in the Dragon. Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which sex genes are targets? Epigenetic enzymes are astonishingly conserved, providing exciting opportunities to draw from human systems to unravel novel signatures of temperature-induced sex switching in reptiles. This project will advance knowledge of developmental programming generally.Read moreRead less
Utilising artificial intelligence to elucidate the physics of galaxies. For decades astronomers have puzzled over the connection between the structure and evolution of galaxies and the role played by host environments. This project aims to resolve this problem by combining multi-wavelength observations, multi-component simulations, and pioneering data analysis using artificial intelligence. In particular, we target the nearby Fornax galaxy cluster as a laboratory for studying galaxy formation in ....Utilising artificial intelligence to elucidate the physics of galaxies. For decades astronomers have puzzled over the connection between the structure and evolution of galaxies and the role played by host environments. This project aims to resolve this problem by combining multi-wavelength observations, multi-component simulations, and pioneering data analysis using artificial intelligence. In particular, we target the nearby Fornax galaxy cluster as a laboratory for studying galaxy formation in dense environments. Using our novel machine learning techniques, we will elucidate the physical mechanisms that drive the rapid evolution of star formation, galactic nuclei, and gas and dust content within Fornax. Our predictions will benefit ongoing and future surveys at the national and international level. Read moreRead less
Australian savannah landscapes: past, present and future. Australian savannahs are productive and culturally and biologically significant landscapes but are vulnerable to climate change. The project will determine savannah function (carbon and water balance) for the present and assess how sensitive they have been to past climate variability. The project will then address how they may respond to future climate change.
Water and the making of urban Australia since 1900. This project aims to produce new understandings of both the historical drivers of today’s urban water systems, and how these systems have impacted on human and ecological welfare. This will be achieved through the first integrated and comparative historical study of the provision, use and cultures of water in Australia’s five largest cities from 1900 to the present. Such historical knowledge is critical at a time when the water systems of Austr ....Water and the making of urban Australia since 1900. This project aims to produce new understandings of both the historical drivers of today’s urban water systems, and how these systems have impacted on human and ecological welfare. This will be achieved through the first integrated and comparative historical study of the provision, use and cultures of water in Australia’s five largest cities from 1900 to the present. Such historical knowledge is critical at a time when the water systems of Australia’s largest cities are under growing pressure from environmental change and population growth. Project findings will inform the development of policies and practices that produce sustainable, equitable urban water systems.Read moreRead less
Nature's mechanisms for leaching and remobilising metals. This project aims to understand the chemical and physical processes that govern reactive transport and metal scavenging in rocky environments. Much of Australia's mineral wealth is the result of the interaction of warm fluids with rocks deep in the Earth over geological timescales. The formation of ore deposits is governed by the physical chemistry of mineral dissolution and crystallisation, and by fluid flow through porous rocks and frac ....Nature's mechanisms for leaching and remobilising metals. This project aims to understand the chemical and physical processes that govern reactive transport and metal scavenging in rocky environments. Much of Australia's mineral wealth is the result of the interaction of warm fluids with rocks deep in the Earth over geological timescales. The formation of ore deposits is governed by the physical chemistry of mineral dissolution and crystallisation, and by fluid flow through porous rocks and fractures. This project integrates innovation in geology, chemistry, and mineral engineering, and will deliver mineral-scale reaction models that will increase efficiency of in-situ mining and leaching technologies. Knowledge generated can be applied to improve mineral exploration, mining, and processing, contributing to unlocking billions of dollars’ worth of resources tied up in low grade, mineralogically complex ores.Read moreRead less
Surviving financial crises: a study of the Australian Government securities market. This project assesses the capacity of the Australian Government securities market to meet investor demand in times of financial crises. The outcomes will provide governments in Australia and other countries with the necessary tools to enhance the efficiency of securities markets and to flag liquidity problems in a timely manner.