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Is there a climatic tipping point for Antarctic Bottom Water formation? Antarctic Bottom Water plays an important role in global ocean circulation and climate and yet its formation is also highly sensitive to climate change. This project will analyse new seafloor, core and water samples from the understudied Cape Darnley, East Antarctica, collected on a voyage in early 2022. This new data will be used in combination with an improved high resolution regional ocean model, to understand modern and ....Is there a climatic tipping point for Antarctic Bottom Water formation? Antarctic Bottom Water plays an important role in global ocean circulation and climate and yet its formation is also highly sensitive to climate change. This project will analyse new seafloor, core and water samples from the understudied Cape Darnley, East Antarctica, collected on a voyage in early 2022. This new data will be used in combination with an improved high resolution regional ocean model, to understand modern and past Antarctic Bottom Water formation under different climate states (warmer and colder than present), to determine if there are climate tipping points for the shut down of Antarctic Bottom Water formation. The anticipated benefits include a better understanding of future climate change on this important water mass.Read moreRead less
Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Macrophage control of mammalian growth and development. The immediate postnatal period in mammals is crucial for survival, long term health and productivity. This project is an international collaboration that aims to investigate how cells of the innate immune system called macrophages control somatic growth and development of mature organ function in the early postnatal period. The project aims to build upon investment in new animals models and a novel discovery to generate significant new know ....Macrophage control of mammalian growth and development. The immediate postnatal period in mammals is crucial for survival, long term health and productivity. This project is an international collaboration that aims to investigate how cells of the innate immune system called macrophages control somatic growth and development of mature organ function in the early postnatal period. The project aims to build upon investment in new animals models and a novel discovery to generate significant new knowledge that will challenge current concepts of mammalian growth control. The outcomes will enhance Australia's international reputation in the fields of physiology, immunology and developmental biology. Read moreRead less
Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be ....Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be used to: develop interventions that improve learning and educational outcomes; counteract age-related memory decline and enable longer work force participation; develop strategies to circumvent the memory loss caused by brain diseases, or improve the design of computer hardware.Read moreRead less
Judges' work, place and psychological health - a national view. This project aims to address the human, juridical and financial costs of judicial officers’ work-related psychological harm. This harm is implicated in early retirement, sick leave and suicide. It threatens appropriate courtroom conduct, procedural fairness and impartial adjudication. The project seeks to generate new knowledge of the stress judicial officers experience and the individual and institutional mechanisms for managing st ....Judges' work, place and psychological health - a national view. This project aims to address the human, juridical and financial costs of judicial officers’ work-related psychological harm. This harm is implicated in early retirement, sick leave and suicide. It threatens appropriate courtroom conduct, procedural fairness and impartial adjudication. The project seeks to generate new knowledge of the stress judicial officers experience and the individual and institutional mechanisms for managing stressors, combining socio-legal and psychological approaches. Expected outcomes include evidence-based understandings to inform recruitment and retention strategies specific to this highly specialized workforce. This should provide significant benefits for judges’ work capacities and courts' delivery of justice.Read moreRead less
Multi-Country Study on Health Effects of Bushfire Air Pollution. Catastrophic bushfires are a major natural disaster, causing serious air pollution. However, aligning bushfire air pollution and public health policies becomes a significant challenge, because limited studies are available on relationships between bushfire air pollution and human health, particularly for the prolonged exposure. We will characterize the nature of the relationships between bushfire air pollution and mortality/morbidi ....Multi-Country Study on Health Effects of Bushfire Air Pollution. Catastrophic bushfires are a major natural disaster, causing serious air pollution. However, aligning bushfire air pollution and public health policies becomes a significant challenge, because limited studies are available on relationships between bushfire air pollution and human health, particularly for the prolonged exposure. We will characterize the nature of the relationships between bushfire air pollution and mortality/morbidity by developing a multi-country study; and estimate the burden of diseases attributed to bushfire air pollution. This project will provide essential scientific evidence to policy-makers and stakeholders in the development, prioritization and implementation of health protection strategies and policies.
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Southern Ocean aerosols: sources, sinks and impact on cloud properties. This project aims to provide fundamental process-level understanding of atmospheric aerosol processes over the Southern Ocean, a region that has a profound influence on the Australian and global climate and where climate models perform poorly. Comprehensive observations during 3 Southern Ocean voyages and land-based measurements will enhance our knowledge of aerosols and cloud formation in that region and provide much-needed ....Southern Ocean aerosols: sources, sinks and impact on cloud properties. This project aims to provide fundamental process-level understanding of atmospheric aerosol processes over the Southern Ocean, a region that has a profound influence on the Australian and global climate and where climate models perform poorly. Comprehensive observations during 3 Southern Ocean voyages and land-based measurements will enhance our knowledge of aerosols and cloud formation in that region and provide much-needed data for improving global climate models. Expected outcomes include more accurate seasonal and latitudinal representations of Southern Ocean aerosol populations, properties and sources. The main benefit includes improvements in weather forecasting and future climate projection for Australia and the Southern Hemisphere.Read moreRead less
Novel governance for marine ecosystems in rapid transition. This project will develop the governance knowledge required to manage rapidly changing marine ecosystems. Australia has the third largest marine estate globally, and its ecosystems support critical economic and sociocultural values. However, human pressures are tipping marine ecosystems into alternate states, inspiring new interventions to sustain industries and communities. New interventions necessitate transitions in governance. Expec ....Novel governance for marine ecosystems in rapid transition. This project will develop the governance knowledge required to manage rapidly changing marine ecosystems. Australia has the third largest marine estate globally, and its ecosystems support critical economic and sociocultural values. However, human pressures are tipping marine ecosystems into alternate states, inspiring new interventions to sustain industries and communities. New interventions necessitate transitions in governance. Expected outcomes include a comparative understanding of novel marine interventions now underway globally, and practical guidance on how to diagnose and implement responsible marine governance. Significant benefits include enhanced governance and sustainability of Australian and international marine ecosystems.Read moreRead less
The contribution of human/marine herbivore interactions to reef degradation. This project aims to define how interactions between human society and herbivores influence marine ecosystem structure and function. It will analyse geographic patterns from recent systematic sampling of reef communities worldwide and study fish, macro-invertebrate and meso-grazer herbivory to identify herbivores’ role in the collapse and recovery of reef ecosystems. This project will examine the match between a critica ....The contribution of human/marine herbivore interactions to reef degradation. This project aims to define how interactions between human society and herbivores influence marine ecosystem structure and function. It will analyse geographic patterns from recent systematic sampling of reef communities worldwide and study fish, macro-invertebrate and meso-grazer herbivory to identify herbivores’ role in the collapse and recovery of reef ecosystems. This project will examine the match between a critical ecosystem function and community structure across local to global scales, including the identification of non-linearities and interactions involving human effects on this process. This research is expected to safeguard marine ecosystems from collapse.Read moreRead less
Profit and Loss: The commercial trade in Indigenous human remains. This project will be the first to investigate the global commercial trade in Indigenous human remains. It will employ a multi-disciplinary approach involving history, economic anthropology, economic history, and data science. The project will generate new knowledge about the 19th century global marketplace in Australian Indigenous human remains, and will reveal whether and how these are involved in the trade’s modern manifestati ....Profit and Loss: The commercial trade in Indigenous human remains. This project will be the first to investigate the global commercial trade in Indigenous human remains. It will employ a multi-disciplinary approach involving history, economic anthropology, economic history, and data science. The project will generate new knowledge about the 19th century global marketplace in Australian Indigenous human remains, and will reveal whether and how these are involved in the trade’s modern manifestations from 1950 to the present. The project will uncover an unknown history, assist repatriation practice, provide information to help reduce the modern trade, and contribute to truth-telling as a precondition of healing and reconciliation.Read moreRead less