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El Niño in a changing climate: novel long-term perspectives from Pacific corals and model simulations. El Niño and La Niña events have a profound influence on Australian drought conditions and rainfall. Forecasting is hampered by short climate records, which do not capture the full range of El Niño dynamics. This project aims to generate records of unprecedented length and spatial coverage from key sites across the western and central equatorial Pacific. Five hundred years of continuous, monthly ....El Niño in a changing climate: novel long-term perspectives from Pacific corals and model simulations. El Niño and La Niña events have a profound influence on Australian drought conditions and rainfall. Forecasting is hampered by short climate records, which do not capture the full range of El Niño dynamics. This project aims to generate records of unprecedented length and spatial coverage from key sites across the western and central equatorial Pacific. Five hundred years of continuous, monthly-resolution climate data will be integrated with output from state-of-the-art climate model simulations to distil the key processes that cause El Niño to vary. This project aims to provide major advances in determining the full range of El Niño and La Niña behaviour, leading to improved forecasts of future changes, with consequences for Australia's water security.Read moreRead less
Comprehending and modelling the workings of the animal brain. Truly understanding how the brain operates is a grand challenge of 21st century neuroscience. Progress toward this goal can be made through studying small-brained animals, like the honey bee. This project aims to use microscopy and pharmacology to analyse the neural mechanisms by which bees learn and classify complex things. This will enable the construction of a computational model of decision making in the bee brain. Analysing this ....Comprehending and modelling the workings of the animal brain. Truly understanding how the brain operates is a grand challenge of 21st century neuroscience. Progress toward this goal can be made through studying small-brained animals, like the honey bee. This project aims to use microscopy and pharmacology to analyse the neural mechanisms by which bees learn and classify complex things. This will enable the construction of a computational model of decision making in the bee brain. Analysing this model will test what is understood about the operation of the animal brain, and what simulates it. This project aims to reveal how neural circuits make complex decisions; establish key principles and foundational studies for comprehending larger more complex brains, and yield new approaches to machine learning.Read moreRead less
Changing your mind by changing your brain: An interventionist perspective on cognitive neuroscience. Functional neuroimaging provides a tremendous amount of information about the brain, but what it shows about the mind is less clear. Addressing this fundamental philosophical question requires developing a detailed account of theory-testing in cognitive neuroscience. This project aims to connect neuroimaging to theories of explanation that focus on the way one variable can make a difference to an ....Changing your mind by changing your brain: An interventionist perspective on cognitive neuroscience. Functional neuroimaging provides a tremendous amount of information about the brain, but what it shows about the mind is less clear. Addressing this fundamental philosophical question requires developing a detailed account of theory-testing in cognitive neuroscience. This project aims to connect neuroimaging to theories of explanation that focus on the way one variable can make a difference to another. By linking neuroimaging to facts about manipulable relationships between the brain and the mind, it will also provide a bridge between neuroimaging and complementary technologies for directly intervening on the brain. This, in turn, will provide a platform from which to explore the theoretical and ethical consequences of direct brain manipulation.Read moreRead less
Indigenising the Semantic Web: Ontologies for Indigenous knowledge and heritage resources on a machine-readable Web. This project will put Australia at the forefront of international efforts to realise a functioning Semantic Web in which all data transactions are handled by machines talking to machines. It addresses the government's call for the creation of infrastructure and e-research tools that enable high-speed distributed access to Indigenous knowledge and culture resources, and its outcome ....Indigenising the Semantic Web: Ontologies for Indigenous knowledge and heritage resources on a machine-readable Web. This project will put Australia at the forefront of international efforts to realise a functioning Semantic Web in which all data transactions are handled by machines talking to machines. It addresses the government's call for the creation of infrastructure and e-research tools that enable high-speed distributed access to Indigenous knowledge and culture resources, and its outcomes will revolutionise the way that these resources are managed, accessed and understood by users everywhere. Indigenous communities will benefit from increased protections for knowledge and heritage resources, and ability to access these in instantaneously customisable ways that promote wellbeing.Read moreRead less
Spatial Cognition—Expressive Representation Formalisms and Effective Reasoning Mechanisms. The project will contribute significantly to the advancement of knowledge in breakthrough science in qualitative spatial reasoning and smart information use in geographic information systems. Expressive spatial languages are important in organising spatial knowledge, defining spatial query languages and guiding spatial data mining. Effective spatial reasoning mechanisms bring theory closer to applications ....Spatial Cognition—Expressive Representation Formalisms and Effective Reasoning Mechanisms. The project will contribute significantly to the advancement of knowledge in breakthrough science in qualitative spatial reasoning and smart information use in geographic information systems. Expressive spatial languages are important in organising spatial knowledge, defining spatial query languages and guiding spatial data mining. Effective spatial reasoning mechanisms bring theory closer to applications including consistency checking and spatial query pre-processing. The project will help in extracting knowledge from massive spatial databases, meeting the growing needs of naive users for spatial information and establishing Australia as a major player in spatial cognition research and in the development of geo-location services.Read moreRead less
Future fables: literature, evolution and artificial intelligence. The future of AI is a site of considerable philosophical and cultural anxiety in the West. Given the future of AI is currently only available to publics through literary or fictional tropes, it is vital that we investigate the historical evolution of these literary or fictional tropes of AI to understand its future direction. This project aims to understand (1) how the post-Darwinian literary imagination has shaped our current anx ....Future fables: literature, evolution and artificial intelligence. The future of AI is a site of considerable philosophical and cultural anxiety in the West. Given the future of AI is currently only available to publics through literary or fictional tropes, it is vital that we investigate the historical evolution of these literary or fictional tropes of AI to understand its future direction. This project aims to understand (1) how the post-Darwinian literary imagination has shaped our current anxieties about AI and (2) how literary and scientific writers after Darwin rethink the future of the human species by imagining the co-evolution of humans, animals and machines. Expected outcomes of the project include conceptual resources to understand the human-nonhuman relation and the future of AI.Read moreRead less
3D Structure determination of biomacromolecular assemblies from sparse data. This project has direct impact on pharmaceutical research: Biomacromolecular interactions are key points for pharmaceutical intervention and detailed structural knowledge of dynamic protein interactions can significantly accelerate drug development. Australia has invested in expensive instrumentation that can be used with new laboratory methods to obtain information on delicately balanced biomacromolecular interactions, ....3D Structure determination of biomacromolecular assemblies from sparse data. This project has direct impact on pharmaceutical research: Biomacromolecular interactions are key points for pharmaceutical intervention and detailed structural knowledge of dynamic protein interactions can significantly accelerate drug development. Australia has invested in expensive instrumentation that can be used with new laboratory methods to obtain information on delicately balanced biomacromolecular interactions, and how they malfunction in disease. This project will provide a computational framework to increase the impact of this investment by integrating measurements from a range of novel technologies and developing understanding of changes in structure of large protein complexes in different functional states.Read moreRead less
Neuronal and behavioural correlates of sensory adaptation. Sensory systems adapt to the statistics of their environment, and the consequences of this adaptation are evident in neuronal activity and in animal’s behaviour. This project will employ a novel paradigm to characterise how adaptation changes the response properties of individual sensory neurons to improve efficiency of information transmission.
Explicit methods in number theory: Computation, theory and application. This project aims to use explicit estimates to unify three problems in number theory: primitive roots, Diophantine quintuples, and linear independence of zeroes of the Riemann zeta-function. It will use computational and analytic number theory to reduce the quintuples problem to a soluble level. Pursuing relations between the zeta zeroes will overhaul many current results. This project will apply its findings about primitive ....Explicit methods in number theory: Computation, theory and application. This project aims to use explicit estimates to unify three problems in number theory: primitive roots, Diophantine quintuples, and linear independence of zeroes of the Riemann zeta-function. It will use computational and analytic number theory to reduce the quintuples problem to a soluble level. Pursuing relations between the zeta zeroes will overhaul many current results. This project will apply its findings about primitive roots to signal processing, cryptography and cybersecurity.Read moreRead less
Development of methods and algorithms to support multidisciplinary optimisation. This project will aim to develop a number of novel and computationally efficient schemes to deal with the key challenges facing multidisciplinary optimisation. These advancements will allow us to solve a number of challenging and intractable problems in science and engineering.