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Physical factors affecting deposition of combustion submicrometer particles in the human lung. Particles generated from combustion sources have a profound effect on human health, yet there is lack of scientific understanding of the role of different physical mechanisms on particle deposition in the lung. This program will advance scientific knowledge in this field through multidisciplinary efforts of a team from QUT and the University of Salzburg, Austria. It aims at quantification of particle d ....Physical factors affecting deposition of combustion submicrometer particles in the human lung. Particles generated from combustion sources have a profound effect on human health, yet there is lack of scientific understanding of the role of different physical mechanisms on particle deposition in the lung. This program will advance scientific knowledge in this field through multidisciplinary efforts of a team from QUT and the University of Salzburg, Austria. It aims at quantification of particle deposition in human lung through experimental studies and advanced modelling. The program will enhance and strengthen the existing collaboration between the universities and its outcome will be of significance in the vital area of human health and risk assessment.Read moreRead less
Raman spectroscopy and imaging of natural and synthetic melanins. The national benefit of this research lies in three main areas. First, this research could lead to a non-invasive diagnostic for melanoma. Second, it could reveal stronger connections between melanin and melanoma development than previously believed and thus inspire possible methods of treatment or prevention of melanoma. Given Australia's high incidence of melanoma, these could have an enormous impact on our health care system. T ....Raman spectroscopy and imaging of natural and synthetic melanins. The national benefit of this research lies in three main areas. First, this research could lead to a non-invasive diagnostic for melanoma. Second, it could reveal stronger connections between melanin and melanoma development than previously believed and thus inspire possible methods of treatment or prevention of melanoma. Given Australia's high incidence of melanoma, these could have an enormous impact on our health care system. Third, it will increase our understanding of the melanin pigment and further establish Australia as a leader in this field. Given the links between melanin and Parkinson's Disease and immune response, this understanding could have greater impact on health care than simply melanoma.Read moreRead less
Increasing the Efficiency of Biomolecular Simulations. This program will extend the range of biomolecular systems that can be modelled with near atomistic precision. It will provide a better understanding of the structure and function of proteins involved in the regulation of membrane fusion and fission as well as shedding light on the assembly of large-scale protein-protein and protein-membrane complexes in general. The work will help place Australia at the forefront of developing simulation t ....Increasing the Efficiency of Biomolecular Simulations. This program will extend the range of biomolecular systems that can be modelled with near atomistic precision. It will provide a better understanding of the structure and function of proteins involved in the regulation of membrane fusion and fission as well as shedding light on the assembly of large-scale protein-protein and protein-membrane complexes in general. The work will help place Australia at the forefront of developing simulation techniques in biomolecular systems, which are widely used within the chemical and pharmaceutical industries. It will also provide opportunities for the training and development of young Australian researchers with top European laboratories. Read moreRead less