Discovery Early Career Researcher Award - Grant ID: De160100636
Funder
Australian Research Council
Summary
The role of marine microbes in the global carbon cycle. This project aims to unravel microbiological processes in the ocean to help quantify the ecosystem services carried out by microbes that support our economy and environment. By recycling vital nutrients, microbes form the basis of the marine food web. In Australia, their contributions support fisheries worth $4.2 billion. Their role in carbon cycling also controls our climate. Yet, their direct productivity remains unquantified. Technical l ....The role of marine microbes in the global carbon cycle. This project aims to unravel microbiological processes in the ocean to help quantify the ecosystem services carried out by microbes that support our economy and environment. By recycling vital nutrients, microbes form the basis of the marine food web. In Australia, their contributions support fisheries worth $4.2 billion. Their role in carbon cycling also controls our climate. Yet, their direct productivity remains unquantified. Technical limitations have restricted our ability to identify the key microbes most responsible for ocean carbon cycling, and to measure their impact. This project plans to combine new approaches in microfluidics, chemistry and oceanography to quantify carbon uptake by individual microbes and provide new understanding of microbe-mediated chemical cycling processes.Read moreRead less
Microbe-produced repellents and their roles in marine pathogen behaviours. Economic losses caused by disease outbreaks in marine fisheries and aquaculture exceed US$6 billion per year globally. Decades of research in human and plant pathogens have revealed that the ability of pathogens to infect their host is governed by behaviours; however our understanding of the chemical cues affecting the behaviour of marine pathogens is very poor. This research program aims to combine new approaches in micr ....Microbe-produced repellents and their roles in marine pathogen behaviours. Economic losses caused by disease outbreaks in marine fisheries and aquaculture exceed US$6 billion per year globally. Decades of research in human and plant pathogens have revealed that the ability of pathogens to infect their host is governed by behaviours; however our understanding of the chemical cues affecting the behaviour of marine pathogens is very poor. This research program aims to combine new approaches in microfluidics and chemical imaging to identify the cues that govern the behaviour of marine pathogens. Expected outcomes include an improved capacity to predict, monitor and manage marine diseases, as well as novel strategies to prevent disease outbreaks, helping to protect Australia’s valuable marine estate.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: Le110100143
Funder
Australian Research Council
Summary
Flexible architecture high-performance computing facility for the intersect consortium of New South Wales. This new supercomputing facility is an important addition to the nation's research infrastructure and will enable world-leading, New South Wales researchers to continue their ground breaking work in increasingly competitive environments. Much of the research to be undertaken at the facility lies in areas of national priority, including frontier technologies and environmental sustainability.
Linkage Infrastructure, Equipment And Facilities - Grant ID: Le120100181
Funder
Australian Research Council
Summary
Strengthening merit-based access and support at the new National Computing Infrastructure petascale supercomputing facility. World-leading high-performance computing is fundamental to Australia's international research success. This facility will provide access to the new National Computational Infrastructure facility by world-leading researchers from six research universities, and sustain ground-breaking work in an increasingly competitive environment.
Seeking causes of unexplained respiratory illness in children by identifying new respiratory viruses. Many respiratory illnesses including the common cold, ear infections, asthma attacks, the flu and pneumonia have no known cause even after all specimen testing is complete. This project will use 'virus hunting' experience to find and sequence as-yet-undiscovered viruses from such specimens so that they can be studied in more detail.
Testing co-evolutionary processes driving venom diversity in tiger snakes. Testing co-evolutionary processes driving venom diversity in tiger snakes. This project aims to examine the geographic variation amongst tiger snakes in anatomy, ecology, and life history traits, and the relationship of these factors to venom toxins and production; and to evaluate the true pharmacological potential of tiger snake venom. This project will investigate the role of venom adaptation in long-term animal evoluti ....Testing co-evolutionary processes driving venom diversity in tiger snakes. Testing co-evolutionary processes driving venom diversity in tiger snakes. This project aims to examine the geographic variation amongst tiger snakes in anatomy, ecology, and life history traits, and the relationship of these factors to venom toxins and production; and to evaluate the true pharmacological potential of tiger snake venom. This project will investigate the role of venom adaptation in long-term animal evolution, by identifying rare venom transcripts involved in providing evolutionary potential for adaptation to environmental change. This is essential as continuing climatic and human-induced alteration of our environment affects southern Australia where many people live, work and interact with native wildlife. Anticipated outcomes are maximizing venom harvests and enhanced snakebite treatment capacity.Read moreRead less
Oxygen isotope discrimination during C4 photosynthesis. Plants with the C4 photosynthetic pathway, like sugarcane and pasture grasses, are vital to Australian agriculture and natural ecosystems. This project will use novel laser spectroscopy to measure oxygen isotope discrimination during photosynthesis and quantify the influence of C4 plants on isotopic signatures of atmospheric CO2.
Discovery Early Career Researcher Award - Grant ID: DE220101087
Funder
Australian Research Council
Funding Amount
$453,580.00
Summary
Impact of shift work on emergency performance, decision making and stress. Sleep and circadian disruptions due to shift work are common for emergency personnel, but their impact on team performance and decision making is poorly understood. Using an ecologically relevant simulated work environment, this project aims to examine how shift work influences work performance and team decision making and identify potential stress-related mechanisms that may underpin impairments in these outcomes. By und ....Impact of shift work on emergency performance, decision making and stress. Sleep and circadian disruptions due to shift work are common for emergency personnel, but their impact on team performance and decision making is poorly understood. Using an ecologically relevant simulated work environment, this project aims to examine how shift work influences work performance and team decision making and identify potential stress-related mechanisms that may underpin impairments in these outcomes. By understanding the role poor sleep and circadian misalignment due to shift work play on work performance, this project will inform industry practices and training approaches designed to optimise workplace safety and emergency performance. This project will benefit emergency personnel and the people who depend on these services.Read moreRead less
Metalloproteomics: A new piece of the systems biology puzzle. Systems biology uses advanced analytical technology to study the complex chemistry of the living cell. Many cellular functions are the result of chemical reactions involving metalloproteins, which are notoriously difficult to study due to the weak bonds between metal and protein that is not normally amenable to traditional proteomic approaches. In partnership with the leading analytical manufacturer Agilent Technologies, this project ....Metalloproteomics: A new piece of the systems biology puzzle. Systems biology uses advanced analytical technology to study the complex chemistry of the living cell. Many cellular functions are the result of chemical reactions involving metalloproteins, which are notoriously difficult to study due to the weak bonds between metal and protein that is not normally amenable to traditional proteomic approaches. In partnership with the leading analytical manufacturer Agilent Technologies, this project aims to adapt and apply advanced mass spectrometry to the study of metalloproteins, developing new methods for studying hundreds of molecules in single experiments. Using the C. elegans model organism the project aims to showcase the importance of metals in biology and develop new solutions for the $2.9 billion proteomics industry.Read moreRead less
Iron, ferroptosis and the biology of ageing. This project aims to determine how and when regulation of iron is lost. Failing iron metabolism during life may dictate the rate of ageing by driving a newly discovered cell death program. Combining biology, chemistry and physics, this collaborative project aims to transform the understanding of the fundamental mechanisms of biological ageing. Anticipated outcomes include new assays for measuring iron in biology and identification of potential pathway ....Iron, ferroptosis and the biology of ageing. This project aims to determine how and when regulation of iron is lost. Failing iron metabolism during life may dictate the rate of ageing by driving a newly discovered cell death program. Combining biology, chemistry and physics, this collaborative project aims to transform the understanding of the fundamental mechanisms of biological ageing. Anticipated outcomes include new assays for measuring iron in biology and identification of potential pathways that regulate death signaling and lifespan. Outcomes will benefit life sciences and biotechnology industries.Read moreRead less