ORCID Profile
0000-0003-1786-0165
Current Organisations
WA Country Health Service
,
Northwestern University
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Publications
Incidence and predictors of HIV, chlamydia and gonorrhoea among men who have sex with men attending a peer-based clinic
Publisher: CSIRO Publishing
Date: 2018
DOI: 10.1071/SH17181
Abstract: Introduction Despite a range of interventions, annual numbers of new diagnoses of HIV infection among men who have sex with men (MSM) in Australia have not declined in recent years. Peer-based sexual health clinics targeting MSM, such as the M Clinic in Perth (WA, Australia), have been put in place to provide safe sex counselling and to increase testing rates among MSM and who are at high risk of HIV infection. The aim of this study was to assess the incidence of HIV, chlamydia and gonorrhoea among men attending the M Clinic. Methods: This was a historical cohort study of repeated M Clinic clients from January 2011 to June 2015 inclusive. Testing and risk factor data from M Clinic client software were used to estimate the incidence of HIV, chlamydia and gonorrhoea and associated factors. Results: The incidence of HIV, chlamydia and gonorrhoea was 1.87, 13.58 and 6.48 per 100 person-years respectively. Older men had a higher incidence of HIV infection but a lower incidence of chlamydia and gonorrhoea than younger men. Conclusions: The HIV incidence was higher than found in similar studies in other Australian sexual health clinics, but the incidence of chlamydia and gonorrhoea was similar. The high HIV incidence among clients of the M Clinic points to the importance of making pre-exposure HIV prophylaxis available to clients of the M Clinic and similar services.
Detection of Neisseria gonorrhoeae and Chlamydia trachomatis from pooled rectal, pharyngeal and urine specimens in men who have sex with men
Publisher: BMJ
Date: 24-10-2018
DOI: 10.1136/SEXTRANS-2017-053303
Abstract: Screening of men who have sex with men (MSM) for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) requires s ling from anorectal and pharyngeal sites in addition to urogenital s ling. Due to the cost of testing multiple anatomical sites in idually testing of pooled specimens has potential merit. The Cepheid GeneXpert CT/NG assay (GeneXpert), which also has potential for point-of-care nucleic acid testing in the sexual health clinic, has not been assessed for pooled specimen testing. We prospectively compared GeneXpert testing of pooled pharyngeal and rectal swabs with urine s les to standard of care testing of in idual specimens from 107 participants using the Roche cobas 4800 CT/NG assay (cobas) for CT and NG in high-risk MSM attending an inner city sexual health clinic. We found testing of pooled pharyngeal, rectal and urine s les by the GeneXpert to have 100% agreement for NG and 94% overall agreement for CT when compared with in idual specimen testing by cobas. For CT testing, 14 cases were detected for both tests, 4for cobas only, 2 for GeneXpert only and 89 participants were negative for both tests. Pooled specimen CT and NG testing by the GeneXpert was accurate when compared with single specimen testing and has potential for screening MSM for CT and NG. The role of pooled specimen testing with the GeneXpert as a point-of-care nucleic acid test in MSM requires further investigation.
Related Organisations
Related Funding Activities
Mathematical And Computational Models For Agrichemical Retention On Plants
Start Date: 2016
End Date: 2018
Funder: Australian Research Council
View Funded Activity