ORCID Profile
0000-0003-3685-174X
Current Organisations
Australian National University
,
Tehran University of Medical Sciences
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Research Topics
In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Top 5 Research Topics
ANZSRC Field of Research (FoR)
Geophysics | Simulation And Modelling | Geodynamics | Geology | Geotectonics | Basin Analysis | Geomechanics | Geophysics Not Elsewhere Classified | Atmospheric Sciences | Artificial Intelligence and Image Processing | Petroleum Geology | Climate Change Processes | Simulation and Modelling | Theoretical and Computational Chemistry not elsewhere classified | Tectonics | Optical Properties of Materials | Physical Geography and Environmental Geoscience | Earth Sciences Not Elsewhere Classified | Information Systems | Resources Engineering and Extractive Metallurgy not elsewhere classified | Natural Resource Management | Structural Geology | Evolutionary Biology not elsewhere classified | Numerical Computation | Data Structures | Interorganisational Information Systems | Resources Engineering and Extractive Metallurgy | Mining Engineering | Petroleum And Reservoir Engineering | Composite and Hybrid Materials | Geology Not Elsewhere Classified | Photonics, Optoelectronics and Optical Communications | Galactic Astronomy | Surface Processes | Natural Hazards | Structural Engineering | Numerical Analysis | Earthquake Seismology | Enzymes | Expert Systems | Mathematical Sciences Not Elsewhere Classified | Computational Fluid Dynamics | Environmental Sciences Not Elsewhere Classified | Condensed Matter Modelling and Density Functional Theory | Bioinformatics | Particle Physics |
ANZSRC Socio-Economic Objective (SEO)
Earth sciences | Mathematical sciences | Oil and gas | Expanding Knowledge in the Earth Sciences | Information processing services | Application packages | Oil and Gas Exploration | Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Physical Sciences | Navy | Natural Hazards not elsewhere classified | Civil Construction Design | Oil and gas | Antarctic and Sub-Antarctic Oceanography | Oil and Gas Extraction | Renewable energy not elsewhere classified (e.g. geothermal) | Cardiovascular System and Diseases | Other | Cement and concrete products | Effects of Climate Change and Variability on Australia (excl. Social Impacts) | Climate Change Models | Aerospace Transport not elsewhere classified | Expanding Knowledge in Technology | Oil Shale and Tar Sands Exploration | Exploration | Climate and Climate Change not elsewhere classified | Expanding Knowledge in Engineering | Expanding Knowledge in the Information and Computing Sciences | Expanding Knowledge in the Agricultural and Veterinary Sciences | Expanding Knowledge in the Biological Sciences | Copper Ore Exploration | Other
Related Links
Publications
The role of mobile belts for the longevity of deep cratonic lithosphere: The Crumple Zone Model
Publisher: American Geophysical Union (AGU)
Date: 15-04-2000
DOI: 10.1029/1999GL008410
Improved green biosynthesis of chitosan decorated Ag- and Co3O4-nanoparticles
Publisher: Elsevier BV
Date: 02-2021
DOI: 10.1016/J.NANO.2020.102331
Abstract: AgNPs@Chitosan and Co
Timing of deformation in the Norseman-Wiluna Belt, Yilgarn Craton, Western Australia
Publisher: Elsevier BV
Date: 10-02-2003
The role of asthenospheric flow during rift propagation and breakup
Publisher: Geological Society of America
Date: 08-12-2018
DOI: 10.1130/G39674.1
The Severe Heterogeneous Asthma Research collaboration, Patient-centred (SHARP) ERS Clinical Research Collaboration: a new dawn in asthma research
Publisher: European Respiratory Society (ERS)
Date: 11-2018
Some thoughts on the stability of cratonic lithosphere: Effects of buoyancy and viscosity
Publisher: American Geophysical Union (AGU)
Date: 10-06-1999
DOI: 10.1029/1999JB900035
Nonadiabatic Topological Energy Pumps with Quasiperiodic Driving
Publisher: American Physical Society (APS)
Date: 11-03-2021
The colorful world of carotenoids: a profound insight on therapeutics and recent trends in nano delivery systems
Publisher: Informa UK Limited
Date: 05-01-2021
DOI: 10.1080/10408398.2020.1867958
Abstract: The therapeutic effects of carotenoids as dietary supplements to control or even treat some specific diseases including diabetic retinopathy, cardiovascular diseases, bacterial infections, as well as breast, prostate, and skin cancer are discussed in this review and also thoughts on future research for their widespread use are emphasized. From the stability standpoint, carotenoids have low bioavailability and bioaccessibility owing to their poor water solubility, deterioration in the presence of environmental stresses such as oxygen, light, and high heat as well as rapid degradation during digestion. Nanoencapsulation technologies as wall or encapsulation materials have been increasingly used for improving food product functionality. Nanoencapsulation is a versatile process employed for the protection, entrapment, and the delivery of food bioactive products including carotenoids from erse environmental conditions for extended shelf lives and for providing controlled release. Therefore, we present here, recent (mostly during the last five years) nanoencapsulation methods of carotenoids with various nanocarriers. To us, this review can be considered as the first highlighting not only the potential therapeutic effects of carotenoids on various diseases but also their most effective nanodelivery systems.HighlightsBioactive compounds are of deep interest to improve food properties.Carotenoids (such as β-carotene and xanthophylls) play indispensable roles in maintaining human health and well-being.A substantial research effort has been carried out on developing beneficial nanodelivery systems for various carotenoids.Nanoencapsulation of carotenoids can enhance their functional properties.Stable nanoencapsulated carotenoids could be utilized in food products.
Timing of formation of Beta Regio and its geodynamical implications
Publisher: American Geophysical Union (AGU)
Date: 2003
DOI: 10.1029/2002JE001889
Effects of school-based physical activity and multi-micronutrient supplementation intervention on growth, health and well-being of schoolchildren in three African countries: the KaziAfya cluster rando
Publisher: Springer Science and Business Media LLC
Date: 06-01-2020
DOI: 10.1186/S13063-019-3883-5
Abstract: In low- and middle-income countries, infectious diseases remain a key public health issue. Additionally, non-communicable diseases are a rapidly growing public health problem that impose a considerable burden on population health. One way to address this dual disease burden, is to incorporate (lifestyle) health promotion measures within the education sector. In the planned study, we will (i) assess and compare physical activity, physical fitness, micronutrient status, body composition, infections with soil-transmitted helminths, Schistosoma mansoni , malaria, inflammatory and cardiovascular health risk markers, cognitive function, health-related quality of life, and sleep in schoolchildren in Côte d’Ivoire, South Africa and Tanzania. We will (ii) determine the bi- and multivariate associations between these variables and (iii) examine the effects of a school-based health intervention that consists of physical activity, multi-micronutrient supplementation, or both. Assuming that no interaction occurs between the two interventions (physical activity and multi-micronutrient supplementation), the study is designed as a cluster-randomised, placebo-controlled trial with a 2 × 2 factorial design. Data will be obtained at three time points: at baseline and at 9 months and 21 months after the baseline assessment. In each country, 1320 primary schoolchildren from grades 1–4 will be recruited. In each school, classes will be randomly assigned to one of four interventions: (i) physical activity (ii) multi-micronutrient supplementation (iii) physical activity plus multi-micronutrient supplementation and (iv) no intervention, which will serve as the control. A placebo product will be given to all children who do not receive multi-micronutrient supplementation. After obtaining written informed consent from the parents/guardians, the children will be subjected to anthropometric, clinical, parasitological and physiological assessments. Additionally, fitness tests will be performed, and children will be invited to wear an accelerometer device for 7 days to objectively assess their physical activity. Children infected with S. mansoni and soil-transmitted helminths will receive deworming drugs according to national policies. Health and nutrition education will be provided to the whole study population independently of the study arm allocation. The study builds on the experience and lessons of a previous study conducted in South Africa. It involves three African countries with different social-ecological contexts to investigate whether results are generalisable across the continent. The study was registered on August 9, 2018, with ISRCTN. 10.1186/ISRCTN29534081 .
On the rise of strongly tilted mantle plume tails
Publisher: Elsevier BV
Date: 2011
Thermal convection below a conducting lid of variable extent: Heat flow scalings and two-dimensional, infinite Prandtl number numerical simulations
Publisher: AIP Publishing
Date: 08-01-2003
DOI: 10.1063/1.1533755
Abstract: Theoretical heat flow scalings are presented for free thermal convection occurring below a conducting lid. Cases in which the lid covers the full extent of the convecting fluid and in which the lid has a variable lateral extent are treated. The scaling predictions are tested against a suite of two-dimensional numerical simulations that solve the full mathematical equations describing infinite Prandtl number thermal convection occurring below a conducting lid. The scaling predictions and simulation results show reasonably good agreement for Rayleigh numbers greater than 107. The scaling predictions are also tested against previous numerical simulations of finite Prandtl number thermal convection below a laterally uniform lid. Scaling predictions and simulations results again show reasonable agreement.
Episodic Precambrian subduction
Publisher: Elsevier BV
Date: 10-2007
Analytical and numerical modeling of viscous anisotropy: A toolset to constrain the role of mechanical anisotropy for regional tectonics and fault loading
Publisher: California Digital Library (CDL)
Date: 15-07-2022
DOI: 10.31223/X5SQ0S
Abstract: Whether mechanical anisotropy is required to explain the dynamics of the lithosphere, in particular near fault zones where it may affect loading stresses, is an important yet open question. If anisotropy affects deformation, how can we quantify its role from observations? Here, we derive analytical solutions and build a theoretical framework to explore how a shear zone with anisotropic viscosity can lead to deviatoric stress heterogeneity as well as non-coaxial principal stress and strain rates. We also develop an open-source finite element approach to explore more complex scenarios in both 2-D and 3-D, and simulate three 3-D scenarios inspired by an anisotropic major strike-slip fault zone, the asthenospheric mantle, and the Leech River Schist above the Cascadia subduction zone. Our findings and new tools may help geoscientists to better understand, detect, and evaluate mechanical anisotropy in natural settings, with potential implications including the transfer of lithospheric stress and deformation including fault loading.
The structural evolution of the deep continental lithosphere
Publisher: Elsevier BV
Date: 2017
Development of a nano biosensor for anti-gliadin detection for Celiac disease based on suspension microarrays
Publisher: IOP Publishing
Date: 24-08-2020
Abstract: Celiac disease is an autoimmune disorder represented by the ingestion of the gluten protein usually found in wheat, barley and rye. To date, ELISA has been the most accurate method for determining the presence of anti-gliadin, which is cumbersome, expensive (compared to a suspension microarray technique), and requires extensive s le preparation. In this study, in order to establish a more accurate assay to identify gliadin at lower concentrations, optical nano biosensors using an indirect immunoassay method for gliadin detection was designed and fabricated. For this, polycaprolactone (PCL) nano- to micro-beads were fabricated as a platform for the gliadin antigen which were optimized and nano functionalized with amine groups for such purposes. The gliadin antibody, which is selective to gliadin, was then added to the beads. Static light scattering tests were conducted to determine PCL particle size distribution and sizes were found from 0.1 to 30 μ m, which is suitable for flowcytometry detection devices. Anti-gliadin detection was performed using an anti IgG mouse antibody conjugated with FITC in a flow cytometry device to detect the smallest particle. Fluorescence intensity was investigated at different concentrations of anti-gliadin and a standard curve used to determine gluten concentration based on fluorescence intensity. Results showed that the fluorescence intensity increased with greater concentrations of anti-gliadin providing a very effective method of detection due to selectivity at a 5 ppm detection limit. This represents a new highly sensitive and fast method for anti-gliadin detection. Further, the disuse of a cross linker and the use of a dedicated antibody at a very low level (1 μ l) made this new method very economical to identify anti-gliadin concentrations at the nano level. In summary, this study provides a new, more accurate and sensitive, as well as less expensive system to detect anti-gliadin for the improved diagnosis of celiac disease.
Multifunctional 3D Hierarchical Bioactive Green Carbon-Based Nanocomposites
Publisher: American Chemical Society (ACS)
Date: 24-06-2021
The influence of a mantle plume head on the dynamics of a retreating subduction zone
Publisher: Geological Society of America
Date: 08-2012
DOI: 10.1130/G32909.1
Incompressible viscous formulations for deformation and yielding of the lithosphere
Publisher: Geological Society of London
Date: 2007
DOI: 10.1144/SP282.19
Effects of initial weakness on rift architecture
Publisher: Geological Society of London
Date: 2007
DOI: 10.1144/SP282.18
Mantle convection modeling with viscoelastic/brittle lithosphere: Numerical methodology and plate tectonic modeling
Publisher: Springer Science and Business Media LLC
Date: 08-2002
Underworld2: Python Geodynamics Modelling for Desktop, HPC and Cloud
Publisher: The Open Journal
Date: 06-03-2020
DOI: 10.21105/JOSS.01797
A Lagrangian integration point finite element method for large deformation modeling of viscoelastic geomaterials
Publisher: Elsevier BV
Date: 2003
Photoluminescent carbon quantum dot/poly-l-Lysine core-shell nanoparticles: A novel candidate for gene delivery
Publisher: Elsevier BV
Date: 02-2021
Anisotropy model for mantle convection
Publisher: Elsevier
Date: 2003
Computational approaches to studying non-linear dynamics of the crust and mantle
Publisher: Elsevier BV
Date: 08-2007
Making, keeping, and may be even losing ancient continental lithosphere
Publisher: Elsevier BV
Date: 08-2006
A model comparison study of large-scale mantle–lithosphere dynamics driven by subduction
Publisher: Elsevier BV
Date: 12-2008
Turning Toxic Nanomaterials into a Safe and Bioactive Nanocarrier for Co-delivery of DOX/pCRISPR
Publisher: American Chemical Society (ACS)
Date: 10-06-2021
Abstract: Hybrid bioactive inorganic-organic carbon-based nanocomposites of reduced graphene oxide (rGO) nanosheets enlarged with multi-walled carbon nanotubes (MWCNTs) were decorated to provide a suitable space for
Morbidity and mortality from road injuries: results from the Global Burden of Disease Study 2017
Publisher: BMJ
Date: 08-01-2020
DOI: 10.1136/INJURYPREV-2019-043302
Abstract: The global burden of road injuries is known to follow complex geographical, temporal and demographic patterns. While health loss from road injuries is a major topic of global importance, there has been no recent comprehensive assessment that includes estimates for every age group, sex and country over recent years. We used results from the Global Burden of Disease (GBD) 2017 study to report incidence, prevalence, years lived with disability, deaths, years of life lost and disability-adjusted life years for all locations in the GBD 2017 hierarchy from 1990 to 2017 for road injuries. Second, we measured mortality-to-incidence ratios by location. Third, we assessed the distribution of the natures of injury (eg, traumatic brain injury) that result from each road injury. Globally, 1 243 068 (95% uncertainty interval 1 191 889 to 1 276 940) people died from road injuries in 2017 out of 54 192 330 (47 381 583 to 61 645 891) new cases of road injuries. Age-standardised incidence rates of road injuries increased between 1990 and 2017, while mortality rates decreased. Regionally, age-standardised mortality rates decreased in all but two regions, South Asia and Southern Latin America, where rates did not change significantly. Nine of 21 GBD regions experienced significant increases in age-standardised incidence rates, while 10 experienced significant decreases and two experienced no significant change. While road injury mortality has improved in recent decades, there are worsening rates of incidence and significant geographical heterogeneity. These findings indicate that more research is needed to better understand how road injuries can be prevented.
gLucifer: Next generation visualization framework for high-performance computational geodynamics
Publisher: Springer Science and Business Media LLC
Date: 26-06-2008
Effective exploration and visualization of geological parameter space
Publisher: American Geophysical Union (AGU)
Date: 10-2003
DOI: 10.1029/2002GC000503
Three-dimensional numerical models of the influence of a buoyant oceanic plateau on subduction zones
Publisher: Elsevier BV
Date: 03-2010
Upper plate controls on deep subduction, trench migrations and deformations at convergent margins
Publisher: Elsevier BV
Date: 03-2010
A new class of equilibrium geotherms in the deep thermal lithosphere of continents
Publisher: Elsevier BV
Date: 30-03-2000
ZnAl nano layered double hydroxides for dual functional CRISPR/Cas9 delivery and enhanced green fluorescence protein biosensor
Publisher: Springer Science and Business Media LLC
Date: 26-11-2020
DOI: 10.1038/S41598-020-77809-1
Abstract: Evaluation of the effect of different parameters for designing a non-viral vector in gene delivery systems has great importance. In this manner, 2D crystals, precisely layered double hydroxides, have attracted the attention of scientists due to their significant adjustability and low-toxicity and low-cost preparation procedure. In this work, the relationship between different physicochemical properties of LDH, including pH, size, zeta potential, and synthesis procedure, was investigated and optimized for CRISPR/Cas9 delivery and reverse fluorescence response to the EGFP. In this manner, ZnAl LDH and ZnAl HMTA LDH were synthesized and characterized and applied in the HEK-293 cell line to deliver CRISPR/Cas9. The results were optimized by different characterizations as well as Gel Electrophoresis and showed acceptable binding ability with the DNA that could be considered as a promising and also new gold-standard for the delivery of CRISPR/Cas9. Also, the relationship of the presence of tertiary amines (in this case, hexamethylenetetramine (HMTA) as the templates) in the structure of the ZnAl LDH, as well as the gene delivery application, was evaluated. The results showed more than 79% of relative cell viability in most of the weight ratios of LDH to CRISPR/Cas9 fully quenching the fluorescence intensity of the EGFP/LDH in the presence of 15 µg mL −1 of the protoporphyrins along with the detection limit of below 2.1 µg mL −1 , the transfection efficiency of around 33% of the GFP positive cell for ZnAl LDH and more than 38% for the ZnAl LDH in the presence of its tertiary amine template.
COVID-19 lockdown leads to seismic noise “quiet period”
Publisher: Front Matter
Date: 23-07-2020
DOI: 10.59350/WERFA-YD829
Geodynamics of oceanic plateau and plume head accretion and their role in Phanerozoic orogenic systems of China
Publisher: Elsevier BV
Date: 2015
Simulating faults and plate boundaries with a transversely isotropic plasticity model
Publisher: Elsevier BV
Date: 03-2016
Moderate-to-Vigorous Physical Activity Is Associated With Cardiorespiratory Fitness Among Primary Schoolchildren Living in Côte d'Ivoire, South Africa, and Tanzania
Publisher: Frontiers Media SA
Date: 19-08-2021
DOI: 10.3389/FPUBH.2021.671782
Abstract: Background: Physical inactivity and low cardiorespiratory fitness (CRF) are independent cardiovascular risk factors among children, but have rarely been investigated concurrently in sub-Saharan Africa. The purpose of this study was to compare physical activity (PA) and CRF of primary schoolchildren living in Côte d'Ivoire (CI), South Africa (ZA), and Tanzania (TZ), to test sex- and age-related differences, and to examine whether PA and CRF are associated with each other. Methods: Baseline data from an ongoing cluster-randomized controlled trial were used, including 499 children from CI (Taabo, 49% girls, M = 8.0 ± 1.6 years), 1,074 children from ZA (Gqeberha, 49% girls, M = 8.3 ± 1.4 years), and 593 children from TZ (Ifakara, 51% girls, M = 9.4 ± 1.7 years). PA was assessed by accelerometry and CRF by a 20 m shuttle-run test. The data were analyzed using multi-/univariate analyses of variance and mixed linear models. Results: Most children met recommendations put forward by the World Health Organization for moderate-to-vigorous PA (MVPA) and achieved high CRF scores. In CI, 89.6% of the children met MVPA recommendations (boys: 91.7%, girls: 87.4%), whereas this rate was 76.9% in ZA (boys: 91.0%, girls: 62.4%), and 93.8% in TZ (boys: 95.5%, girls: 92.0%). Children from TZ had the highest CRF and MVPA levels, followed by children from CI and ZA. Boys had higher MVPA levels than girls, whereas girls engaged in more sedentary behavior. Sex differences were strongest in ZA. Sedentary behavior and MVPA were higher among older schoolchildren compared to their younger peers. Higher MVPA, but not sedentary behavior, was associated with better CRF. Conclusions: In all three settings, higher levels of MVPA were associated with higher CRF scores. Nevertheless, children living in the most urbanized setting (such as observed in ZA) were physically less active and had lower CRF than peers living in more rural areas (such as observed in CI and TZ). Particularly for girls, urbanization might increase the risk for insufficient MVPA, which may have negative effects on their CRF, thus negatively influencing health and well-being at later age.
Evolution and diversity of subduction zones controlled by slab width
Publisher: Springer Science and Business Media LLC
Date: 03-2007
DOI: 10.1038/NATURE05615
Abstract: Subducting slabs provide the main driving force for plate motion and flow in the Earth's mantle, and geodynamic, seismic and geochemical studies offer insight into slab dynamics and subduction-induced flow. Most previous geodynamic studies treat subduction zones as either infinite in trench-parallel extent (that is, two-dimensional) or finite in width but fixed in space. Subduction zones and their associated slabs are, however, limited in lateral extent (250-7,400 km) and their three-dimensional geometry evolves over time. Here we show that slab width controls two first-order features of plate tectonics-the curvature of subduction zones and their tendency to retreat backwards with time. Using three-dimensional numerical simulations of free subduction, we show that trench migration rate is inversely related to slab width and depends on proximity to a lateral slab edge. These results are consistent with retreat velocities observed globally, with maximum velocities (6-16 cm yr(-1)) only observed close to slab edges ( 2,000 km) retreat velocities are always slow (<2.0 cm yr(-1)). Models with narrow slabs ( or =4,000 km) are nearly stationary in the centre and develop a convex geometry, whereas trench retreat increases towards concave-shaped edges. Additionally, we identify periods (5-10 Myr) of slow trench advance at the centre of wide slabs. Such wide-slab behaviour may explain mountain building in the central Andes, as being a consequence of its tectonic setting, far from slab edges.
Supplementary material to "Arc volcanism, carbonate platform evolution and palaeo-atmospheric CO<sub>2</sub>: Components and interactions in the deep carbon cycle&
Publisher: Copernicus GmbH
Date: 19-09-2017
<p>Biodegradable Nanopolymers in Cardiac Tissue Engineering: From Concept Towards Nanomedicine</p>
Publisher: Informa UK Limited
Date: 06-2020
DOI: 10.2147/IJN.S245936
Physical Activity, Cardiorespiratory Fitness and Clustered Cardiovascular Risk in South African Primary Schoolchildren from Disadvantaged Communities: A Cross-Sectional Study
Publisher: MDPI AG
Date: 21-02-2021
Abstract: The coexistence of multiple cardiovascular risk factors has been reported in school-aged children from the age of nine years, but most evidence stems from high-income countries. This cross-sectional study aimed at describing the cardiovascular health risk, physical activity (PA) behavior and cardiorespiratory fitness (CRF) levels of South African primary schoolchildren, and at examining the associations between PA/CRF and a composite measure of cardiovascular risk. Cross-sectional data from 832 primary schoolchildren (grade 1–4) were analyzed. Total cholesterol/HDL ratio, triglycerides, systolic/diastolic blood pressure, body fat, and glycated hemoglobin were assessed as cardiovascular risk markers. Data were analyzed via mixed linear regressions and analyses of covariance. Overall, 24.2% of the participants did not meet current PA standards. Higher CRF/PA were associated with lower body fat and lower clustered cardiovascular risk (p 0.05). When categorizing children into CRF/PA quartiles, a lower clustered cardiovascular risk gradient was found in children with higher CRF (p 0.05) or PA (p 0.05). Our data shows that higher CRF/PA is associated with lower clustered cardiovascular risk already from a young age. Given that clustered cardiovascular risk present during childhood can track into adulthood, we advocate for PA participation and a healthy weight from a young age onwards.
A Model for Trap Door Flow from a Deep Container
Publisher: Springer International Publishing
Date: 2019
Crustal transpressional fault geometry influenced by viscous lower crustal flow
Publisher: Geological Society of America
Date: 21-06-2022
DOI: 10.1130/G50061.1
Abstract: The San Andreas fault (California, USA) is near vertical at shallow (& km) depth. Geophysical surveys along the San Andreas fault reveal that, at depths of 10–20 km, it dips ~50–70° to the southwest near the Western Transverse Ranges and dips northeast in the San Gorgonio region. We investigate the possible origin of along-strike geometric variations of the fault using a three-dimensional thermomechanical model. For two blocks separated by transpressional faults, our model shows that viscous lower crustal material moves from the high-viscosity block into the low-viscosity block. Fault plane-normal flow in the viscous lower crust rotates the fault plane due to the simple shear flow at the brittle-ductile transition depth. This occurs irrespective of initial fault dip direction. Rheological variations used to model the lower crust of Southern California are verified by independent observations. Block extrusion due to lower crustal viscosity variation facilitates the formation of the Garlock Fault and sustains the geometric complexity of the fault.
Stripy: A Python module for (constrained) triangulation in Cartesian coordinates and on a sphere.
Publisher: The Open Journal
Date: 13-06-2019
DOI: 10.21105/JOSS.01410
Nanotechnology-assisted microfluidic systems: from bench to bedside
Publisher: Future Medicine Ltd
Date: 02-2021
Abstract: With significant advancements in research technologies, and an increasing global population, microfluidic and nanofluidic systems (such as point-of-care, lab-on-a-chip, organ-on-a-chip, etc) have started to revolutionize medicine. Devices that combine micron and nanotechnologies have increased sensitivity, precision and versatility for numerous medical applications. However, while there has been extensive research on microfluidic and nanofluidic systems, very few have experienced wide-spread commercialization which is puzzling and deserves our collective attention. For the above reasons, in this article, we review research advances that combine micro and nanotechnologies to create the next generation of nanomaterial-based microfluidic systems, the latest in their commercialization success and failure and highlight the value of these devices both in industry and in the laboratory.
Large amplitude folding in finely layered viscoelastic rock structures
Publisher: Springer Science and Business Media LLC
Date: 08-2002
Heat flow scaling for mantle convection below a conducting lid: Resolving seemingly inconsistent modeling results regarding continental heat flow
Publisher: American Geophysical Union (AGU)
Date: 04-2001
DOI: 10.1029/2000GL008484
Numerical Methods for Mantle Convection
Publisher: Elsevier
Date: 2015
Multidisciplinary Constraints on the Abundance of Diamond and Eclogite in the Cratonic Lithosphere
Publisher: American Geophysical Union (AGU)
Date: 07-2018
DOI: 10.1029/2018GC007534
Abstract: Some seismic models derived from tomographic studies indicate elevated shear‐wave velocities (≥4.7 km/s) around 120–150 km depth in cratonic lithospheric mantle. These velocities are higher than those of cratonic peridotites, even assuming a cold cratonic geotherm (i.e., 35 mW/m 2 surface heat flux) and accounting for compositional heterogeneity in cratonic peridotite xenoliths and the effects of anelasticity. We reviewed various geophysical and petrologic constraints on the nature of cratonic roots (seismic velocities, lithology/mineralogy, electrical conductivity, and gravity) and explored a range of permissible rock and mineral assemblages that can explain the high seismic velocities. These constraints suggest that diamond and eclogite are the most likely high‐ V s candidates to explain the observed velocities, but matching the high shear‐wave velocities requires either a large proportion of eclogite ( vol.%) or the presence of up to 3 vol.% diamond, with the exact values depending on peridotite and eclogite compositions and the geotherm. Both of these estimates are higher than predicted by observations made on natural s les from kimberlites. However, a combination of ≤20 vol.% eclogite and ~2 vol.% diamond may account for high shear‐wave velocities, in proportions consistent with multiple geophysical observables, data from natural s les, and within mass balance constraints for global carbon. Our results further show that cratonic thermal structure need not be significantly cooler than determined from xenolith thermobarometry.
Influence of trench width on subduction hinge retreat rates in 3‐D models of slab rollback
Publisher: American Geophysical Union (AGU)
Date: 03-2006
DOI: 10.1029/2005GC001056
Scientific software frameworks and grid computing: Improving programming productivity
Publisher: Springer US
Date: 2007
Creation and preservation of cratonic lithosphere: Seismic constraints and geodynamic models
Publisher: American Geophysical Union
Date: 2006
DOI: 10.1029/164GM07
How are academic achievement and inhibitory control associated with physical fitness, soil-transmitted helminth infections, food insecurity and stunting among South African primary schoolchildren?
Publisher: Springer Science and Business Media LLC
Date: 03-05-2021
DOI: 10.1186/S12889-021-10779-9
Abstract: Cardiovascular fitness has been associated with both executive function and academic achievement in multiple cohort studies including children and adolescents. However, research is scarce among children from low- and middle-income countries. Hence, this paper focuses on South African primary schoolchildren living in marginalized areas and examines if academic achievement and inhibitory control can be explained by children’s age, socioeconomic status, soil-transmitted helminth infections, food insecurity, stunting, grip strength, and cardiorespiratory fitness. The s le of this cross-sectional study consisted of 1277 children (48% girls, mean age: 8.3 years). Data were assessed via questionnaires, stool s les, anthropometric measurements, 20 m shuttle run test, grip strength test, Flanker task, and school grades. Data were analysed with mixed linear regression models with random intercepts for school classes, separately for boys and girls. Higher socioeconomic status was most closely associated with academic achievement among boys ( p 0.05), whereas higher levels of cardiorespiratory fitness and not being stunted explained most variance in academic achievement in girls ( p 0.05). Higher age turned out to be associated with better performance in the Flanker task ( p 0.01). Additionally, in boys, higher grip strength was associated with better information processing and inhibitory control of attention ( p 0.01), whereas in girls, higher cardiorespiratory fitness levels were positively associated with these cognitive abilities ( p 0.05). Academic performance has been shown to be compromised in schoolchildren living in marginalised areas, compared to schoolchildren in less disadvantaged parts of South Africa. The present study suggests that cardiorespiratory fitness and grip strength are two potentially modifiable factors that are associated with children’s academic achievement and cognitive performance, and that should be targeted in future school-based interventions.
Plate tectonics and convection in the Earth's mantle: toward a numerical simulation
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 2000
DOI: 10.1109/5992.841793
Formation of cratonic lithosphere during the initiation of plate tectonics
Publisher: Geological Society of America
Date: 06-04-2018
DOI: 10.1130/G39943.1
Inferences on Australia's heat flow and thermal structure from mantle convection modelling results
Publisher: Geological Society of America
Date: 2003
Correction to “Turning Toxic Nanomaterials into a Safe and Bioactive Nanocarrier for Co-delivery of DOX/pCRISPR”
Publisher: American Chemical Society (ACS)
Date: 14-02-2023
Influence of soil-transmitted helminth infections on physical activity, physical fitness, and cardiovascular disease risk in primary schoolchildren in Gqeberha, South Africa
Publisher: Cold Spring Harbor Laboratory
Date: 29-01-2023
DOI: 10.1101/2023.01.27.23285061
Abstract: School-aged children in low- and middle-income countries carry the highest burden of intestinal helminth infections, such as soil-transmitted helminths (STH). STH infections have been associated with negative consequences for child physical and cognitive development and wellbeing. Thus, the aim of this study was to determine the association of STH infections in schoolchildren from Gqeberha, focusing on physical activity, physical fitness, and clustered cardiovascular disease (CVD) risk score. This cross-sectional study involved 680 schoolchildren (356 girls and 324 boys mean age 8.19 years, SD±1.4) from disadvantaged communities in Gqeberha (formerly, Port Elizabeth), South Africa. Stool s les were collected and examined for STH infections using the Kato-Katz method. Physical activity (accelerometer) and physical fitness (grip strength, 20 m shuttle run) were measured using standard procedures. Furthermore, anthropometry, blood pressure, as well as glycated haemoglobin and lipid profile from capillary blood s les were assessed. We employed one-way ANOVAs to identify the associations of STH infections in terms of species and infection intensity with physical activity, physical fitness, and clustered CVD risk score. We found a low STH infection prevalence (7.2%) in our study, with participants infected with at least one intestinal helminth species. In comparison to their non-infected peers, children infected with STH had lower mean grip strength scores, but higher mean VO2max estimation and higher levels of MVPA (p .001). When considering type and intensity of infection, a positive association of A. lumbricoides infection and MVPA was found. In contrast, light T. trichiura -infected children had significantly lower grip strength scores compared to non-infected children. VO2max and MVPA were positively associated with light T. trichiura infection. No significant association between the clustered CVD risk score and infection with any STH species was evident. STH-infected children had lower grip strength scores than their non-infected peers, yet, achieved higher VO2max and MVPA scores. Our study highlights that the type and intensity of STH infection is relevant in understanding the disease burden of STH infections on children’s health. The findings of our study must be interpreted cautiously due to the low infection rate, and more research is needed in s les with higher prevalence rates or case-control designs.
Magnetic carbon–based nanocomposite decorated with palladium complex for co-delivery of DOX/pCRISPR
Publisher: Elsevier BV
Date: 12-2022
Ellipsis 3D: A particle-in-cell finite-element hybrid code for modelling mantle convection and lithospheric deformation
Publisher: Elsevier BV
Date: 12-2006
The Nature of subduction on the early Earth
Publisher: Elsevier BV
Date: 08-2006
Point-of-Use Rapid Detection of SARS-CoV-2: Nanotechnology-Enabled Solutions for the COVID-19 Pandemic
Publisher: MDPI AG
Date: 20-07-2020
DOI: 10.3390/IJMS21145126
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the COVID-19 pandemic that has been spreading around the world since December 2019. More than 10 million affected cases and more than half a million deaths have been reported so far, while no vaccine is yet available as a treatment. Considering the global healthcare urgency, several techniques, including whole genome sequencing and computed tomography imaging have been employed for diagnosing infected people. Considerable efforts are also directed at detecting and preventing different modes of community transmission. Among them is the rapid detection of virus presence on different surfaces with which people may come in contact. Detection based on non-contact optical techniques is very helpful in managing the spread of the virus, and to aid in the disinfection of surfaces. Nanomaterial-based methods are proven suitable for rapid detection. Given the immense need for science led innovative solutions, this manuscript critically reviews recent literature to specifically illustrate nano-engineered effective and rapid solutions. In addition, all the different techniques are critically analyzed, compared, and contrasted to identify the most promising methods. Moreover, promising research ideas for high accuracy of detection in trace concentrations, via color change and light-sensitive nanostructures, to assist fingerprint techniques (to identify the virus at the contact surface of the gas and solid phase) are also presented.
Inverse modelling in geology by interactive evolutionary computation
Publisher: Elsevier BV
Date: 10-2003
Arc volcanism, carbonate platform evolution and palaeo-atmospheric CO<sub>2</sub>: Components and interactions in the deep carbon cycle
Publisher: Copernicus GmbH
Date: 19-09-2017
DOI: 10.5194/CP-2017-112
Abstract: Abstract. Carbon dioxide (CO2) liberated at arc volcanoes that intersect buried carbonate platforms plays a larger role in influencing atmospheric CO2 than those active margins lacking buried carbonate platforms. This study investigates the contribution of carbonate-intersecting arc activity on palaeo-atmospheric CO2 levels over the past 410 million years by integrating a plate motion model with an evolving carbonate platform development model. Our modelled subduction zone lengths and carbonate-intersecting arc lengths approximate arc activity with time, and can be used as input into fully-coupled models of CO2 flux between deep and shallow reservoirs. Continuous and cross-wavelet as well as wavelet coherence analyses were used to evaluate trends between carbonate-intersecting arc activity, non-carbonate-intersecting arc activity and total global subduction zone lengths and the proxy-CO2 record between 410 Ma and the present. Wavelet analysis revealed significant linked periodic behaviour between 75–50 Ma, where global carbonate-intersecting arc activity is relatively high and where peaks in palaeo-atmospheric CO2 is correlated with peaks in global carbonate-intersecting arc activity, characterised by a ~ 32 Myr periodicity and a 10 Myr lag of CO2 peaks after carbonate-intersecting arc length peaks. The linked behaviour may suggest that the relative abundance of carbonate-intersecting arcs played a role in affecting global climate during the Late Cretaceous to Early Paleogene greenhouse. At all other times, atmospheric CO2 emissions from carbonate-intersecting arcs were not correlated with the proxy-CO2 record. Our analysis did not support the idea that carbonate-intersecting arc activity is more important than non-carbonate intersecting arc activity in driving changes in palaeo-atmospheric CO2 levels. This suggests that tectonic controls are more elaborate than the subduction-related volcanic emissions component or that other feedback mechanisms between the geosphere, atmosphere and biosphere played larger roles in modulating climate in the Phanerozoic.
Facilitating research collaboration in the Australian geoscience community using CloudStor
Publisher: IEEE
Date: 12-2010
Longevity and stability of cratonic lithosphere: Insights from numerical simulations of coupled mantle convection and continental tectonics
Publisher: American Geophysical Union (AGU)
Date: 06-2003
DOI: 10.1029/2002JB001859
Effects of continental configuration on mantle heat loss
Publisher: American Geophysical Union (AGU)
Date: 10-06-2013
DOI: 10.1002/GRL.50547
Abstract: Two‐dimensional (2D) and three‐dimensional (3D) simulations are used to explore the effects of continental distribution on mantle convection. In both 2D and 3D, at total surface areas 50%, internal temperature is weakly sensitive to continental configuration. Mantle heat flux values show mild variations with changing configuration. In 3D, at total continental area 50%, the dependence of mantle heat loss on continental configuration becomes stronger. Mantle temperature continues to increase with total continental area but now varies by 5%–7% with changing configurations. When distributed, continents can cause flow patterns to become locked. This leads to significant variations in mantle temperature below continental and oceanic regions. This differs from the expectation that supercontinents would preferentially lead to large lateral variations in mantle temperatures and suggests that insulation‐induced thermal anomalies could exist below continents today if they have remained fixed relative to mantle flow (e.g., Africa).
Prevalence of Stunting and Relationship between Stunting and Associated Risk Factors with Academic Achievement and Cognitive Function: A Cross-Sectional Study with South African Primary School Childre
Publisher: MDPI AG
Date: 16-04-2021
Abstract: Childhood stunting can have negative long-term consequences on cognitive development, academic achievement, and economic productivity later in life. We determined the prevalence of stunting and examined whether stunting and associated risk factors (low dietary ersity, insufficient hemoglobin, food insecurity, and soil-transmitted helminth (STH) infections) are associated with academic achievement and cognitive function among South African children living in marginalized communities. A cross-sectional s le of 1277 children (aged 5–12 years) was analyzed. Stunting was defined according to 2007 WHO growth references. Cognitive functioning was measured with the computerized Flanker task and academic performance via school grades. Blood and stool s les were collected to obtain hemoglobin level and STH infection. Dietary ersity was assessed by a food frequency questionnaire. Associations were examined via mixed linear regression (with school class as a random intercept). Nine percent of the children were stunted (95% CI: 7.6–10.8%). Low dietary ersity (β = 0.13, p = 0.004), food insecurity (β = −0.12, p = 0.034), and stunting (β = −0.13, p = 0.031) were associated with poorer end of the year results among girls. No such associations were found among boys. No significant associations were found for socioeconomic status and hemoglobin levels. The prevalence of stunting and STH infections were low in the present s le. Risk factors seem differently associated with girls’ and boys’ academic achievement. Promoting nutrition may help to promote academic achievement among girls living in low- and middle-income countries.
Numerical modelling of earthquake cycles based on Navier-Stokes equations with Viscoelastic-plasticity rheology
Publisher: Authorea, Inc.
Date: 09-02-2023
DOI: 10.22541/ESSOAR.167591079.95480514/V1
Abstract: Visco-elastic-plastic modelling approaches for long-term tectonic deformation assume that co-seismic fault displacement can be integrated over 1,000s-10,000s years (tens of earthquake cycles) with the appropriate failure law, and that short-timescale fluctuations in the stress field due to in idual earthquakes have no effect on long-term behavior. Models of the earthquake rupture process generally assume that the tectonic (long-range) stress field or kinematic boundary conditions are steady over the course of multiple earthquake cycles. In this study, we develop a numerical framework that embeds earthquake rupture dynamics into a long-term tectonic deformation model by adding inertial terms and using highly adaptive time-stepping that can capture deformation at plate-motion rates as well as in idual earthquakes. We reproduce benchmarks at the earthquake timescale to demonstrate the effectiveness of our approach. We then discuss how these high-resolution models degrade if the time-step cannot capture the rupture process accurately and, from this, infer when it is important to consider coupling of the two timescales and the level of accuracy required. To build upon these benchmarks, we undertake a generic study of a thrust fault in the crust with a prescribed geometry. We find that lower crustal rheology affects the periodic time of characteristic earthquake cycles and the inter-seismic, free-surface deformation rate. In particular, the relaxation of the surface of a cratonic region (with a relatively strong lower crust) has a characteristic double-peaked uplift profile that persists for thousands of years after a major slip event. This pattern might be diagnostic of active faults in cratonic regions.
Green synthesis of CuO- and Cu2O-NPs in assistance with high-gravity: The flowering of nanobiotechnology
Publisher: IOP Publishing
Date: 04-08-2020
Synthesis of green benzamide-decorated UiO-66-NH2 for biomedical applications
Publisher: Elsevier BV
Date: 07-2022
DOI: 10.1016/J.CHEMOSPHERE.2022.134359
Abstract: Metal-organic frameworks (MOFs) biocompatible systems can host enzymes/bacteria/viruses. Herein we synthesized a series of fatty acid amide hydrolase (FAAH)-decorated UiO-66-NH
A review on computer‐aided chemogenomics and drug repositioning for rational COVID ‐19 drug discovery
Publisher: Wiley
Date: 22-09-2022
DOI: 10.1111/CBDD.14136
Abstract: Application of materials capable of energy harvesting to increase the efficiency and environmental adaptability is sometimes reflected in the ability of discovery of some traces in an environment―either experimentally or computationally―to enlarge practical application window. The emergence of computational methods, particularly computer‐aided drug discovery (CADD), provides le opportunities for the rapid discovery and development of unprecedented drugs. The expensive and time‐consuming process of traditional drug discovery is no longer feasible, for nowadays the identification of potential drug candidates is much easier for therapeutic targets through elaborate in silico approaches, allowing the prediction of the toxicity of drugs, such as drug repositioning (DR) and chemical genomics (chemogenomics). Coronaviruses (CoVs) are cross‐species viruses that are able to spread expeditiously from the into new host species, which in turn cause epidemic diseases. In this sense, this review furnishes an outline of computational strategies and their applications in drug discovery. A special focus is placed on chemogenomics and DR as unique and emerging system‐based disciplines on CoV drug and target discovery to model protein networks against a library of compounds. Furthermore, to demonstrate the special advantages of CADD methods in rapidly finding a drug for this deadly virus, numerous ex les of the recent achievements grounded on molecular docking, chemogenomics, and DR are reported, analyzed, and interpreted in detail. It is believed that the outcome of this review assists developers of energy harvesting materials and systems for detection of future unexpected kinds of CoVs or other variants.
<p>Burgeoning Polymer Nano Blends for Improved Controlled Drug Release: A Review</p>
Publisher: Informa UK Limited
Date: 06-2020
DOI: 10.2147/IJN.S252237
Contrasted East Asia and South America tectonics driven by deep mantle flow
Publisher: Elsevier BV
Date: 07-2019
Scaling in Underworld
Publisher: Front Matter
Date: 09-03-2021
DOI: 10.59350/QVGM0-YZ754
Role of faults, nonlinear rheology, and viscosity structure in generating plates from instantaneous mantle flow models
Publisher: American Geophysical Union (AGU)
Date: 10-07-1998
DOI: 10.1029/98JB00605
Shear banding analysis of plastic models formulated for incompressible viscous flows
Publisher: Elsevier BV
Date: 12-2008
A director theory for visco-elastic folding instabilities in multilayered rock
Publisher: Elsevier BV
Date: 06-2002
Formation of sequences in the cratonic interior of North America by interaction between mantle, eustatic, and stratigraphic processes
Publisher: Geological Society of America
Date: 12-1997
Preconditioned iterative methods for Stokes flow problems arising in computational geodynamics
Publisher: Elsevier BV
Date: 12-2008
Crystal structure study of a beta'-copper vanadium bronze, CuxV2O5 (x = 0.63), by X-ray and convergent beam electron diffraction
Publisher: International Union of Crystallography (IUCr)
Date: 19-01-2005
DOI: 10.1107/S0108768104027739
Abstract: The single-crystal structure of a β′-copper vanadium bronze, Cu 0.63 V 2 O 5 , has been studied at room temperature and 9.6 K, and compared with that of the β-sodium vanadium bronze, Na 0.33 V 2 O 5 , structure. No convincing evidence to oppose an assignment of centrosymmetric C 2/ m symmetry to the structure was identified using the X-ray data. A subsequent convergent beam electron diffraction (CBED) experiment was performed and confirmed the C 2/ m space group. The oxygen–vanadium atom framework of Cu 0.63 V 2 O 5 is close to that of Na 0.33 V 2 O 5 . However, in the copper compound the Cu atoms are located in two positions: Cu1 in the 4( i ) position with x = 0.541, y = 0 and z = 0.345, and Cu2 in the 8( j ) position with x = 0.529, y = 0.038 and z = 0.357. The crystal structure changes little with temperature. Disorder of the Cu ion over two sites is seen at 9.6 K. This suggests that distribution of the Cu atoms over two sites is of a more static than dynamic nature.
Scaling of time‐dependent stagnant lid convection: Application to small‐scale convection on Earth and other terrestrial planets
Publisher: American Geophysical Union (AGU)
Date: 10-09-2000
DOI: 10.1029/2000JB900197
A note on continents and the Earth’s Urey ratio
Publisher: Elsevier BV
Date: 09-2011
Rainforest fragmentation and the demography of the economically important palm Oenocarpus bacaba in central Amazonia
Publisher: Springer Science and Business Media LLC
Date: 20-06-2008
Dripping or delamination? A range of mechanisms for removing the lower crust or lithosphere
Publisher: Oxford University Press (OUP)
Date: 10-05-2017
DOI: 10.1093/GJI/GGX202
Engineered Biomimetic Membranes for Organ-on-a-Chip.
Publisher: American Chemical Society (ACS)
Date: 08-11-2022
DOI: 10.1021/ACSBIOMATERIALS.2C00531
Abstract: Organ-on-a-chip (OOC) systems are engineered nanobiosystems to mimic the physiochemical environment of a specific organ in the body. Among various components of OOC systems, biomimetic membranes have been regarded as one of the most important key components to develop controllable biomimetic bioanalysis systems. Here, we review the preparation and characterization of biomimetic membranes in comparison with the features of the extracellular matrix. After that, we review and discuss the latest applications of engineered biomimetic membranes to fabricate various organs on a chip, such as liver, kidney, intestine, lung, skin, heart, vasculature and blood vessels, brain, and multiorgans with perspectives for further biomedical applications.
The role of slabs and oceanic plate geometry in the net rotation of the lithosphere, trench motions, and slab return flow
Publisher: American Geophysical Union (AGU)
Date: 04-2012
DOI: 10.1029/2011GC003934
Associations of Growth Impairment and Body Composition among South African School-Aged Children Enrolled in the KaziAfya Project
Publisher: MDPI AG
Date: 09-08-2021
DOI: 10.3390/NU13082735
Abstract: (1) Background: Early childhood malnutrition may result in increased fat mass (FM) among school-aged children in low- and middle-income countries (LMICs). We explored whether South African children with shorter stature have greater overall and abdominal FM compared to normal stature children. (2) Methods: Baseline assessments of body composition and weight were determined among school-aged children enrolled in a randomized controlled trial in Port Elizabeth, South Africa, using bioelectrical impedance analysis. Multiple linear regression models tested associations of children’s height and degree of stunting with FM, fat free mass (FFM), truncal fat mass (TrFM), and truncal fat free mass (TrFFM) overall and by sex. (3) Results: A total of 1287 children (619 girls, 668 boys) were assessed at baseline. Reduced child height was associated with higher FM and lower FFM and TrFFM, but these associations were reversed with increases in height. Girls classified as mildly or moderately/severely stunted had higher FM and TrFM but lower FFM and TrFFM, while no association was found for boys. (4) Conclusions: Our study suggests that efforts to reduce the non-communicable disease burden in LMICs should target growth-impaired children who may have greater overall FM and greater abdominal FM.
Thermal convection with a water ice I rheology: Implications for icy satellite evolution
Publisher: Elsevier BV
Date: 2006
Growth of the hemispheric dichotomy and the cessation of plate tectonics on Mars
Publisher: American Geophysical Union (AGU)
Date: 02-2004
DOI: 10.1029/2003JE002172
Geodynamic controls on diamond deposits
Publisher: Elsevier BV
Date: 08-2005
A new driving mechanism for backarc extension and backarc shortening through slab sinking induced toroidal and poloidal mantle flow: Results from dynamic subduction models with an overriding plate
Publisher: American Geophysical Union (AGU)
Date: 06-2013
DOI: 10.1002/JGRB.50173
Controlled Gene Delivery Systems: Nanomaterials and Chemical Approaches
Publisher: American Scientific Publishers
Date: 05-2020
Abstract: Successful gene therapy depends on the design of effective gene delivery systems. A gene delivery system is considered a powerful tool for the release of genetic material within cells resulting in a change in cell functions and protein production. The release of genes in a controlled manner by using appropriate carriers facilitates their release without side effects and increases the expression of genes at the released site. It is expected that significant changes in the combination of several genes and drugs can be provided by developing treatment systems sensitive to different stimuli such as redox potential, pH variations, temperature gradients, light irradiation, and enzyme activity. The most important advantages for the release of genes and stimuli-responsive therapeutics include delivering vectors locally, reducing side effects and causing no toxicity to distant tissues while at the same time reducing the immune response to the vectors. In this review, we aim to discuss different types of gene carriers involved in the controlled transfer of nucleic acids (non-viral inorganic and organic nanoparticles (NPs) and virus-like particles (VLPs)) as well as the simultaneous transfer of several genes and/or drugs into cells or different tissues, providing for an efficient and safe treatment of numerous diseases.
Emergent Anisotropy and Flow Alignment in Viscous Rock
Publisher: Springer Science and Business Media LLC
Date: 12-2004
Free-surface formulation of mantle convection-I. Basic theory and application to plumes
Publisher: Oxford University Press (OUP)
Date: 12-1996
ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy”
Publisher: Wiley
Date: 30-04-2019
DOI: 10.1111/ALL.13701
Abstract: Pharmacists are trusted health care professionals. Many patients use over-the-counter (OTC) medications and are seen by pharmacists who are the initial point of contact for allergic rhinitis management in most countries. The role of pharmacists in integrated care pathways (ICPs) for allergic diseases is important. This paper builds on existing studies and provides tools intended to help pharmacists provide optimal advice/interventions/strategies to patients with rhinitis. The Allergic Rhinitis and its Impact on Asthma (ARIA)-pharmacy ICP includes a diagnostic questionnaire specifically focusing attention on key symptoms and markers of the disease, a systematic Diagnosis Guide (including differential diagnoses), and a simple flowchart with proposed treatment for rhinitis and asthma multimorbidity. Key prompts for referral within the ICP are included. The use of technology is critical to enhance the management of allergic rhinitis. However, the ARIA-pharmacy ICP should be adapted to local healthcare environments/situations as regional (national) differences exist in pharmacy care.
A fast robust algorithm for computing discrete Voronoi diagrams
Publisher: Springer Science and Business Media LLC
Date: 16-12-2009
Variations and controls on crustal thermal regimes in Southeastern Australia
Publisher: Elsevier BV
Date: 2018
Multiscale Particle-In-Cell Method: From Fluid to Solid Mechanics
Publisher: InTech
Date: 14-03-2012
DOI: 10.5772/26419
High-gravity-assisted green synthesis of palladium nanoparticles
Publisher: Elsevier BV
Date: 11-2020
Polymer-Coated NH2-UiO-66 for the Codelivery of DOX/pCRISPR
Publisher: American Chemical Society (ACS)
Date: 23-02-2021
Fault spacing in continental strike-slip shear zones
Publisher: Elsevier BV
Date: 2020
Boosting the Quantum State of a Cavity with Floquet Driving
Publisher: American Physical Society (APS)
Date: 04-05-2022
Three-Dimensional Mantle Convection With Continental Crust: First-Generation Numerical Simulations
Publisher: American Meteorological Society
Date: 1999
Interactive inversion in geosciences
Publisher: Society of Exploration Geophysicists
Date: 07-2001
DOI: 10.1190/1.1487069
Abstract: Inversion algorithms numerically evaluate the mismatch between model and data to guide the search for minima in parameter spaces. In an alternative approach, the numerical evaluation of data misfit can be replaced by subjectively judging the solution’s quality. This widens the class of problems that can be treated within the framework of formal inverse theory—in particular, various geophysical/geological/geodynamic applications in which structural similarity between model and data determines the quality of the fit. In this situation, prior knowledge, experience, and even personal intuition are crucial. This approach also provides a simple way to include such expertise in more traditional numeric applications, e.g., to treat ambiguous problems and disregard geologically unfeasible solutions from the inverse search.
The role of viscoelasticity in subducting plates
Publisher: American Geophysical Union (AGU)
Date: 11-2014
DOI: 10.1002/2014GC005507
Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017
Publisher: BMJ
Date: 24-04-2020
DOI: 10.1136/INJURYPREV-2019-043494
Abstract: Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries. We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs). In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100 000. In 1990, there were 354 064 302 (95% uncertainty interval: 338 174 876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100 000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100 000 to 3267 (3058 to 3505). Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care.
Intermediate-Depth Earthquakes Controlled by Incoming Plate Hydration Along Bending-Related Faults
Publisher: American Geophysical Union (AGU)
Date: 04-04-2019
DOI: 10.1029/2018GL081585
Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning
Publisher: Public Library of Science (PLoS)
Date: 28-07-2021
DOI: 10.1371/JOURNAL.PNTD.0008824
Abstract: Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. In order to classify IUs that include locations that are environmentally suitable, we used receiver operating characteristic (ROC) analysis to identify an optimal threshold for suitability concordant with locations where onchocerciasis has been previously detected. This threshold value was then used to classify IUs (more suitable or less suitable) based on the location within the IU with the largest mean prediction. Mean estimates of environmental suitability suggest large areas across West and Central Africa, as well as focal areas of East Africa, are suitable for onchocerciasis transmission, consistent with the presence of current control and elimination of transmission efforts. The ROC analysis identified a mean environmental suitability index of 0·71 as a threshold to classify based on the location with the largest mean prediction within the IU. Of the IUs considered for mapping surveys, 50·2% exceed this threshold for suitability in at least one 5 × 5-km location. The formidable scale of data collection required to map onchocerciasis endemicity across the African continent presents an opportunity to use spatial data to identify areas likely to be suitable for onchocerciasis transmission. National onchocerciasis elimination programmes may wish to consider prioritising these IUs for mapping surveys as human resources, laboratory capacity, and programmatic schedules may constrain survey implementation, and possibly delaying MDA initiation in areas that would ultimately qualify.
A graphical user interface for particle-in-cell finite element analysis of lithospheric deformation and mantle convection in two dimensions
Publisher: Elsevier BV
Date: 08-2007
Styles of rifting and fault spacing in numerical models of crustal extension
Publisher: American Geophysical Union (AGU)
Date: 06-2015
DOI: 10.1002/2014JB011813
Fluid flow during slab unbending and dehydration: Implications for intermediate‐depth seismicity, slab weakening and deep water recycling
Publisher: American Geophysical Union (AGU)
Date: 2012
DOI: 10.1029/2011GC003860
Underworld's lightweight cloud for online classrooms.
Publisher: Front Matter
Date: 06-04-2020
DOI: 10.59350/MW43C-VN265
The Fingerprints of Flexure in Slab Seismicity
Publisher: American Geophysical Union (AGU)
Date: 08-2020
DOI: 10.1029/2019TC005894
Decompression melting driving intraplate volcanism in Australia: Evidence from magnetotelluric sounding
Publisher: American Geophysical Union (AGU)
Date: 28-01-2015
DOI: 10.1002/2014GL060088
Stimulus-responsive sequential release systems for drug and gene delivery
Publisher: Elsevier BV
Date: 10-2020
Cretaceous Vertical Motion of Australia and the AustralianAntarctic Discordance
Publisher: American Association for the Advancement of Science (AAAS)
Date: 06-03-1998
DOI: 10.1126/SCIENCE.279.5356.1499
Abstract: A three-dimensional model of mantle convection in which the known history of plate tectonics is imposed predicts the anomalous Cretaceous vertical motion of Australia and the present-day distinctive geochemistry and geophysics of the Australian-Antarctic Discordance. The dynamic models infer that a subducted slab associated with the long-lived Gondwanaland-Pacific converging margin passed beneath Australia during the Cretaceous, partially stagnated in the mantle transition zone, and is presently being drawn up by the Southeast Indian Ridge.
Significance of strain localization in the lower crust for structural evolution and thermal history of metamorphic core complexes
Publisher: American Geophysical Union (AGU)
Date: 04-2007
DOI: 10.1029/2004TC001768
Green chemistry and coronavirus
Publisher: Elsevier BV
Date: 06-2021
Explaining StGermain: An aspect oriented environment for building extensible computational mechanics modeling software
Publisher: IEEE
Date: 2007
A window for plate tectonics in terrestrial planet evolution?
Publisher: Elsevier BV
Date: 06-2016
The Impact of a Very Weak and Thin Upper Asthenosphere on Subduction Motions
Publisher: American Geophysical Union (AGU)
Date: 11-11-2019
DOI: 10.1029/2019GL085212
Abstract: Recent geophysical observations report the presence of a very weak and thin upper asthenosphere underneath subducting oceanic plates at convergent margins. Along these margins, trench migrations are significantly slower than plate convergence rates. We use numerical models to assess the role of a weak upper asthenospheric layer on plate and trench motions. We show that the presence of this layer alone can enhance an advancing trend for the motion of the plate and h er trench retreat. This mechanism provides a novel and alternative explanation for the slow rates of trench migration and fast‐moving plates observed globally at natural subduction zones.
Constraints on the lateral strength of slabs from three-dimensional dynamic flow models
Publisher: Elsevier BV
Date: 02-1996
Effects of a non-coaxial flow rule on shear bands in viscous-plastic materials
Publisher: Springer Science and Business Media LLC
Date: 25-02-2011
Zn-rich (GaN)1−x(ZnO)x
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D0NJ06310J
Abstract: The synthesis of (GaN) 1−x (ZnO) x with the assistance of high-gravity using a green approach for the first time, with the application of delivering pCRISPR.
Cenozoic Tectonics of Western North America Controlled by Evolving Width of Farallon Slab
Publisher: American Association for the Advancement of Science (AAAS)
Date: 16-07-2010
Abstract: The Basin and Range Province of western North America—exemplified by the alternating mountain ridge and valley landscapes across nearly the entire U.S. state of Nevada—started to form ∼50 million years ago through a series of extensions of the continental crust. Prior to that, massive mountain-building collisions at the boundary between North America and the Pacific Ocean formed a subduction zone and compressed the continent. By combining observations of global subduction zone velocities with numerical modeling, Schellart et al. (p. 316 ) demonstrate that the thinning of the subducting portion of the oceanic plate controlled how and when the transition from compression to extension occurred. Even today, where the much smaller remnant oceanic plate continues to slowly subduct below North America in the Pacific Northwest, the width of the slab and not its age controls the velocity of subduction. Indeed, this relation may explain the dynamics of other modern subduction zones, from South America to Japan.
A climate induced transition in the tectonic style of a terrestrial planet
Publisher: Elsevier BV
Date: 07-2008
Elasticity, Yielding and Episodicity in Simple Models of Mantle Convection
Publisher: Springer Science and Business Media LLC
Date: 09-2006
Is grip strength linked to body composition and cardiovascular risk markers in primary schoolchildren? Cross-sectional data from three African countries
Publisher: BMJ
Date: 06-2022
DOI: 10.1136/BMJOPEN-2021-052326
Abstract: Muscular strength represents a specific component of health-related fitness. Hand grip strength (HGS) is used as an indicator for musculoskeletal fitness in children. HGS can also be used as a marker of cardiometabolic risk, but most available HGS data are derived from Western high-income countries. Therefore, this study examines whether HGS is associated with body composition and markers of cardiovascular risk in children from three sub-Saharan African countries. Cross-sectional study. Public primary schools (grade 1–4) in Taabo (Côte d’Ivoire), Gqeberha (South Africa) and Ifakara (Tanzania). Data from 467 children from Côte d’Ivoire (210 boys, 257 girls), 864 children from South Africa (429 boys, 435 girls) and 695 children from Tanzania (334 boys, 361 girls) were analysed. Body composition (assessed via bioelectrical impedance analysis) was the primary outcome. Cardiovascular risk markers were considered as secondary outcome. Blood pressure was measured with an oscillometric monitor, and blood markers (cholesterol, triglycerides, glycated haemoglobin) via Afinion point-of-care testing. HGS (independent variable) was assessed with a hydraulic hand dynamometer. Inferential statistics are based on mixed linear regressions and analyses of covariance. Across all study sites, higher HGS was associated with lower body fat, higher muscle mass and higher fat-free mass ( p .001, 3.9%–10.0% explained variance), both in boys and girls. No consistent association was found between HGS and cardiovascular risk markers. HGS assessment is popular due to its simplicity, feasibility, practical utility and high reliability of measurements. This is one of the first HGS studies with children from sub-Saharan Africa. There is a great need for further studies to examine whether our findings can be replicated, to develop reference values for African children, to establish links to other health outcomes, and to explore whether HGS is associated with later development of cardiovascular risk markers. ISRCTN29534081 .
Date-Leaf Carbon Particles for Green Enhanced Oil Recovery
Publisher: MDPI AG
Date: 07-04-2022
DOI: 10.3390/NANO12081245
Abstract: Green enhanced oil recovery (GEOR) is an environmentally friendly enhanced oil recovery (EOR) process involving the injection of green fluids to improve macroscopic and microscopic sweep efficiencies while boosting tertiary oil production. Carbon nanomaterials such as graphene, carbon nanotube (CNT), and carbon dots have gained interest for their superior ability to increase oil recovery. These particles have been successfully tested in EOR, although they are expensive and do not extend to GEOR. In addition, the application of carbon particles in the GEOR method is not well understood yet, requiring thorough documentation. The goals of this work are to develop carbon nanoparticles from biomass and explore their role in GEOR. The carbon nanoparticles were prepared from date leaves, which are inexpensive biomass, through pyrolysis and ball-milling methods. The synthesized carbon nanomaterials were characterized using the standard process. Three formulations of functionalized and non-functionalized date-leaf carbon nanoparticle (DLCNP) solutions were chosen for core floods based on phase behavior and interfacial tension (IFT) properties to examine their potential for smart water and green chemical flooding. The carboxylated DLCNP was mixed with distilled water in the first formulation to be tested for smart water flood in the sandstone core. After water flooding, this formulation recovered 9% incremental oil of the oil initially in place. In contrast, non-functionalized DLCNP formulated with (the biodegradable) surfactant alkyl polyglycoside and NaCl produced 18% more tertiary oil than the CNT. This work thus provides new green chemical agents and formulations for EOR applications so that oil can be produced more economically and sustainably.
Insulation and depletion due to thickened crust: Effects on melt production on Mars and Earth
Publisher: American Geophysical Union (AGU)
Date: 21-07-2005
DOI: 10.1029/2005GL022855
Bio-multifunctional noncovalent porphyrin functionalized carbon-based nanocomposite
Publisher: Springer Science and Business Media LLC
Date: 23-03-2021
DOI: 10.1038/S41598-021-86119-Z
Abstract: Herein, in a one-pot method, the reduced graphene oxide layers with the assistance of multiwalled carbon nanotubes were decorated to provide a suitable space for the in situ growth of CoNi 2 S 4 , and the porphyrins were incorporated into the layers as well to increase the sensitivity of the prepared nanostructure. The prepared nanocomposite can establish π–π interactions between the genetic material and on the surface of porphyrin rings. Also, hydrogen bonds between genetic domains and the porphyrin’ nitrogen and the surface hydroxyl groups are probable. Furthermore, the potential donor–acceptor relationship between the d 7 transition metal, cobalt, and the genetic material provides a suitable way to increase the interaction and gene loading , and transfections. The reason for this phenomenon was optimized to increase the EGFP by up to 17.9%. Furthermore, the sensing ability of the nanocomposite towards H 2 O 2 was investigated. In this regard, the limit of detection of the H 2 O 2 obtained 10 µM. Also, the in situ biosensing ability in the HEK-293 and PC12 cell lines was evaluated by the addition of PMA. The nanocomposite showed the ability to detect the released H 2 O 2 after adding the minimum amount of 120 ng/mL of the PMA.
Oceanic Residual Topography Agrees With Mantle Flow Predictions at Long Wavelengths
Publisher: American Geophysical Union (AGU)
Date: 04-11-2017
DOI: 10.1002/2017GL074800
Management of severe asthma: A European Respiratory Society/American Thoracic Society guideline,Лечение рекомендации и Американского тяжелой Европейского торакального бронхиальной респираторного общества астмы: общества
Publisher: Scientific and Practical Reviewed Journal Pulmonology
Date: 10-06-2021
DOI: 10.18093/0869-0189-2021-31-3-272-295
Abstract: This document provides clinical recommendations for the management of severe asthma. Comprehensive evidence syntheses, including metaanalyses, were performed to summarise all available evidence relevant to the European Respiratory Society/American Thoracic Society Task Force’s questions. The evidence was appraised using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach and the results were summarised in evidence profiles. The evidence syntheses were discussed and recommendations formulated by a multidisciplinary Task Force of asthma experts, who made specific recommendations on six specific questions. After considering the balance of desirable and undesirable consequences, quality of evidence, feasibility, and acceptability of various interventions, the Task Force made the following recommendations: • suggest using anti-interleukin (IL)-5 and anti-IL-5 receptor α for severe uncontrolled adult eosinophilic asthma phenotypes • suggest using a blood eosinophil cut-point ≥150 μL −1 to guide anti-IL-5 initiation in adult patients with severe asthma • suggest considering specific eosinophil (≥260 μL −1 ) and exhaled nitric oxide fraction (≥19.5 ppb) cut-offs to identify adolescents or adults with the greatest likelihood of response to anti-IgE therapy • suggest using inhaled tiotropium for adolescents and adults with severe uncontrolled asthma despite Global Initiative for Asthma (GINA) step 4 – 5 or National Asthma Education and Prevention Program (NAEPP) step 5 therapies • suggest a trial of chronic macrolide therapy to reduce asthma exacerbations in persistently symptomatic or uncontrolled patients on GINA step 5 or NAEPP step 5 therapies, irrespective of asthma phenotype • suggest using anti-IL-4/13 for adult patients with severe eosinophilic asthma and for those with severe corticosteroid-dependent asthma regardless of blood eosinophil levels. These recommendations should be reconsidered as new evidence becomes available.
Overriding plate controls on subduction evolution
Publisher: American Geophysical Union (AGU)
Date: 08-2014
DOI: 10.1002/2014JB011163
Mapping the Alaskan Moho
Publisher: Seismological Society of America (SSA)
Date: 10-10-2018
DOI: 10.1785/0220180222
A benchmark study on mantle convection in a 3‐D spherical shell using CitcomS
Publisher: American Geophysical Union (AGU)
Date: 10-2008
DOI: 10.1029/2008GC002048
Phenomenology of the Prethermal Many-Body Localized Regime
Publisher: American Physical Society (APS)
Date: 08-09-2023
Anisotropic viscous models of large-deformation Mohr–Coulomb failure
Publisher: Informa UK Limited
Date: 21-07-2006
UWGeodynamics: A teaching and research tool for numerical geodynamic modelling
Publisher: The Open Journal
Date: 11-04-2019
DOI: 10.21105/JOSS.01136
Mode of crustal extension determined by rheological layering
Publisher: Elsevier BV
Date: 07-2005
Diatoms with Invaluable Applications in Nanotechnology, Biotechnology, and Biomedicine: Recent Advances
Publisher: American Chemical Society (ACS)
Date: 21-06-2021
Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline
Publisher: European Respiratory Society (ERS)
Date: 26-09-2019
DOI: 10.1183/13993003.00588-2019
Abstract: This document provides clinical recommendations for the management of severe asthma. Comprehensive evidence syntheses, including meta-analyses, were performed to summarise all available evidence relevant to the European Respiratory Society/American Thoracic Society Task Force's questions. The evidence was appraised using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach and the results were summarised in evidence profiles. The evidence syntheses were discussed and recommendations formulated by a multidisciplinary Task Force of asthma experts, who made specific recommendations on six specific questions. After considering the balance of desirable and undesirable consequences, quality of evidence, feasibility, and acceptability of various interventions, the Task Force made the following recommendations: 1) suggest using anti-interleukin (IL)-5 and anti-IL-5 receptor α for severe uncontrolled adult eosinophilic asthma phenotypes 2) suggest using a blood eosinophil cut-point ≥150 μL −1 to guide anti-IL-5 initiation in adult patients with severe asthma 3) suggest considering specific eosinophil (≥260 μL −1 ) and exhaled nitric oxide fraction (≥19.5 ppb) cut-offs to identify adolescents or adults with the greatest likelihood of response to anti-IgE therapy 4) suggest using inhaled tiotropium for adolescents and adults with severe uncontrolled asthma despite Global Initiative for Asthma (GINA) step 4–5 or National Asthma Education and Prevention Program (NAEPP) step 5 therapies 5) suggest a trial of chronic macrolide therapy to reduce asthma exacerbations in persistently symptomatic or uncontrolled patients on GINA step 5 or NAEPP step 5 therapies, irrespective of asthma phenotype and 6) suggest using anti-IL-4/13 for adult patients with severe eosinophilic asthma and for those with severe corticosteroid-dependent asthma regardless of blood eosinophil levels. These recommendations should be reconsidered as new evidence becomes available.
Many-body localization with quasiperiodic driving
Publisher: American Physical Society (APS)
Date: 19-04-2022
Overview of adaptive finite element analysis in computational geodynamics
Publisher: Elsevier BV
Date: 10-2013
A double slip non-coaxial flow rule for viscous-plastic Cosserat materials
Publisher: Springer Science and Business Media LLC
Date: 17-11-2011
Modelling of Non-coaxial Viscoplastic Deformation in Geodynamics
Publisher: David Publishing Company
Date: 28-08-2014
Stress Recovery for the Particle-in-cell Finite Element Method
Publisher: California Digital Library (CDL)
Date: 25-05-2020
Stress recovery for the particle-in-cell finite element method
Publisher: Elsevier BV
Date: 02-2021
How long can diamonds remain stable in the continental lithosphere?
Publisher: Elsevier BV
Date: 08-2003
A push in the right direction: exploring the role of Zealandia collision in Eocene Pacific-Australia plate motion changes
Publisher: Authorea, Inc.
Date: 11-06-2023
Denuding a Craton: Thermochronology Record of Phanerozoic Unroofing From the Pilbara Craton, Australia
Publisher: American Geophysical Union (AGU)
Date: 09-2020
DOI: 10.1029/2019TC005988
Improving subduction interface implementation in dynamic numerical models
Publisher: Copernicus GmbH
Date: 28-06-2019
Abstract: Abstract. Numerical subduction models often implement an entrained weak layer (WL) to facilitate decoupling of the slab and upper plate. This approach is attractive in its simplicity, and can provide stable, asymmetric subduction systems that persist for many tens of millions of years. In this study we undertake a methodological analysis of the WL approach, and use these insights to guide improvements to the implementation. The issue that primarily motivates the study is the emergence of significant spatial and temporal thickness variations within the WL. We show that these variations are mainly the response to volumetric flux gradients, caused by the change in boundary conditions as the WL material enters and exits the zone of decoupling. The time taken to reach a quasi-equilibrium thickness profile will depend on the total plate convergence, and is around 7 Myr for the models presented here. During the transient stage, width variations along the WL can exceed 4×, which may impact the effective strength of the interface, through physical effects if the rheology is linear, or simply if the interface becomes inadequately numerically resolved. The transient stage also induces strong sensitivity to model resolution. By prescribing a variable-thickness WL at the outset of the model, and by controlling the limits of the layer thickness during the model evolution, we find improved stability and resolution convergence of the models.
Rate effects in dense granular materials: Linear stability analysis and the fall of granular columns
Publisher: Wiley
Date: 13-01-2011
DOI: 10.1002/NAG.895
Adjoint inversion of the thermal structure of Southeastern Australia
Publisher: Oxford University Press (OUP)
Date: 12-08-2019
DOI: 10.1093/GJI/GGZ368
Abstract: The variation of temperature in the crust is difficult to quantify due to the sparsity of surface heat flow observations and lack of measurements on the thermal properties of rocks at depth. We examine the degree to which the thermal structure of the crust can be constrained from the Curie depth and surface heat flow data in Southeastern Australia. We cast the inverse problem of heat conduction within a Bayesian framework and derive its adjoint so that we can efficiently find the optimal model that best reproduces the data and prior information on the thermal properties of the crust. Efficiency gains obtained from the adjoint method facilitate a detailed exploration of thermal structure in SE Australia, where we predict high temperatures within Precambrian rocks of 650 °C due to relatively high rates of heat production (0.9–1.4 μW m−3). In contrast, temperatures within dominantly Phanerozoic crust reach only 520 °C at the Moho due to the low rates of heat production in Cambrian mafic volcanics. A combination of the Curie depth and heat flow data is required to constrain the uncertainty of lower crustal temperatures to ±73 °C. We also show that parts of the crust are unconstrained if either data set is omitted from the inversion.
Modelling rates and distribution of subsidence due to dynamic topography over subducting slabs: is it possible to identify dynamic topography from ancient strata?
Publisher: Wiley
Date: 12-1999
The influence of carbonate platform interactions with subduction zone volcanism on palaeo-atmospheric CO<sub>2</sub> since the Devonian
Publisher: Copernicus GmbH
Date: 21-06-2018
Abstract: Abstract. The CO2 liberated along subduction zones through intrusive/extrusive magmatic activity and the resulting active and diffuse outgassing influences global atmospheric CO2. However, when melts derived from subduction zones intersect buried carbonate platforms, decarbonation reactions may cause the contribution to atmospheric CO2 to be far greater than segments of the active margin that lacks buried carbon-rich rocks and carbonate platforms. This study investigates the contribution of carbonate-intersecting subduction zones (CISZs) to palaeo-atmospheric CO2 levels over the past 410 million years by integrating a plate motion and plate boundary evolution model with carbonate platform development through time. Our model of carbonate platform development has the potential to capture a broader range of degassing mechanisms than approaches that only account for continental arcs. Continuous and cross-wavelet analyses as well as wavelet coherence are used to evaluate trends between the evolving lengths of carbonate-intersecting subduction zones, non-carbonate-intersecting subduction zones and global subduction zones, and are examined for periodic, linked behaviour with the proxy CO2 record between 410 Ma and the present. Wavelet analysis reveals significant linked periodic behaviour between 60 and 40 Ma, when CISZ lengths are relatively high and are correlated with peaks in palaeo-atmospheric CO2, characterised by a 32–48 Myr periodicity and a ∼ 8–12 Myr lag of CO2 peaks following CISZ length peaks. The linked behaviour suggests that the relative abundance of CISZs played a role in affecting global climate during the Palaeogene. In the 200–100 Ma period, peaks in CISZ lengths align with peaks in palaeo-atmospheric CO2, but CISZ lengths alone cannot be determined as the cause of a warmer Cretaceous–Jurassic climate. Nevertheless, across the majority of the Phanerozoic, feedback mechanisms between the geosphere, atmosphere and biosphere likely played dominant roles in modulating climate. Our modelled subduction zone lengths and carbonate-intersecting subduction zone lengths approximate magmatic activity through time, and can be used as input into fully coupled models of CO2 flux between deep and shallow carbon reservoirs.
The influence of non-coaxiality on shear banding in viscous-plastic materials
Publisher: Springer Science and Business Media LLC
Date: 17-03-2010
Long-lived transcontinental sediment transport pathways of East Gondwana
Publisher: Geological Society of America
Date: 15-04-2019
DOI: 10.1130/G45915.1
ACcESS: Australia's contribution to the iSERVO Institute's development
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
Date: 07-2005
DOI: 10.1109/MCSE.2005.64
3D printing of bioactive materials for drug delivery applications
Publisher: Informa UK Limited
Date: 22-08-2022
DOI: 10.1080/17425247.2022.2112944
Abstract: Three-dimensional (3D) printing, also known as additive manufacturing (AM), is a modern technique/technology, which makes it possible to construct 3D objects from computer-aided design (CAD) digital models. This technology can be used in the progress of drug delivery systems, where porosity has played important role in attaining an acceptable level of biocompatibility and biodegradability with improved therapeutic effects. 3D printing may also provide the user possibility to control the dosage of each ingredient in order to a specific purpose, and makes it probable to improve the formulation of drug delivery systems. This article covers the 3D printing technologies, bioactive materials including natural and synthetic polymers as well as some ceramics and minerals and their roles in drug delivery systems. This technology is feasible to fabricate drug products by incorporating multiple drugs in different parts in such a mode that these drugs can release from the section at a predetermined rate. Furthermore, this 3D printing technology has the potential to transform personalized therapy to various age-groups by design flexibility and precise dosing. In recent years, the potential use of this technology can be realized in a clinical situation where patients will acquire in idualized medicine as per their requirement.
Novel Pt-Ag3PO4/CdS/Chitosan Nanocomposite with Enhanced Photocatalytic and Biological Activities
Publisher: MDPI AG
Date: 23-11-2020
DOI: 10.3390/NANO10112320
Abstract: Decorating photocatalysts with noble metal nanoparticles (e.g., Pt) often increases the catalysts’ photocatalytic activity and biomedical properties. Here, a simple and inexpensive method has been developed to prepare a Pt-Ag3PO4/CdS/chitosan composite, which was characterized and used for the visible light-induced photocatalytic and antibacterial studies. This synthesized composite showed superior photocatalytic activity for methylene blue degradation as a hazardous pollutant (the maximum dye degradation was observed in 90 min of treatment) and killing of Gram positive bacterial (Staphylococcus aureus and Bacillus cereus) as well as Gram negative bacteria (Klebsiella pneumoniae, Salmonella typhimurium, Escherichia coli, and Pseudomonas aeruginosa) under visible light irradiation. The antibacterial activity of CdS, CdS/Ag3PO4, and Pt-Ag3PO4/CdS/chitosan against E. coli, Pseudomonas aeruginosa, Salmonella typhimurium, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus cereus showed the zone of inhibition (mm) under visible light and under dark conditions at a concentration of 20 µg mL−1. Furthermore, the cell viability of the CdS/chitosan, Ag3PO4, Ag3PO4/CdS/chitosan, and Pt-Ag3PO4/CdS/chitosan were investigated on the human embryonic kidney 293 cells (HEK-293), Henrietta Lacks (HeLa), human liver cancer cell line (HepG2), and pheochromocytoma (PC12) cell lines. In addition, the results indicated that the photodegradation rate for Pt-Ag3PO4/CdS/chitosan is 3.53 times higher than that of CdS and 1.73 times higher than that of the CdS/Ag3PO4 composite. Moreover, Pt-Ag3PO4/CdS/chitosan with an optimal amount of CdS killed large areas of different bacteria and different cells separately in a shorter time period under visible-light irradiation, which shows significantly higher efficiency than pure CdS and other CdS/Ag3PO4 composites. The superb performances of this composite are attributed to its privileged properties, such as retarded recombination of photoinduced electron/hole pairs and a large specific surface area, making Pt-Ag3PO4/CdS/chitosan a valuable composite that can be deployed for a range of important applications, such as visible light-induced photocatalysis and antibacterial activity.
Role of temperature‐dependent viscosity and surface plates in spherical shell models of mantle convection
Publisher: American Geophysical Union (AGU)
Date: 10-05-2000
DOI: 10.1029/2000JB900003
Mantle convection with a brittle lithosphere: thoughts on the global tectonic styles of the Earth and Venus
Publisher: Oxford University Press (OUP)
Date: 25-06-1998
Evolution and dynamics of subduction zones from 4-D geodynamic models
Publisher: Elsevier BV
Date: 08-2006
The thermal structure of stable continental lithosphere within a dynamic mantle
Publisher: Elsevier BV
Date: 06-2004
Porphyrin Molecules Decorated on Metal-Organic Frameworks for Multi-Functional Biomedical Applications
Publisher: MDPI AG
Date: 17-11-2021
DOI: 10.3390/BIOM11111714
Abstract: Metal–organic frameworks (MOFs) have been widely used as porous nanomaterials for different applications ranging from industrial to biomedicals. An unpredictable one-pot method is introduced to synthesize NH2-MIL-53 assisted by high-gravity in a greener media for the first time. Then, porphyrins were deployed to adorn the surface of MOF to increase the sensitivity of the prepared nanocomposite to the genetic materials and in-situ cellular protein structures. The hydrogen bond formation between genetic domains and the porphyrin’ nitrogen as well as the surface hydroxyl groups is equally probable and could be considered a milestone in chemical physics and physical chemistry for biomedical applications. In this context, the role of incorporating different forms of porphyrins, their relationship with the final surface morphology, and their drug/gene loading efficiency were investigated to provide a predictable pattern in regard to the previous works. The conceptual phenomenon was optimized to increase the interactions between the biomolecules and the substrate by reaching the limit of detection to 10 pM for the Anti-cas9 protein, 20 pM for the single-stranded DNA (ssDNA), below 10 pM for the single guide RNA (sgRNA) and also around 10 nM for recombinant SARS-CoV-2 spike antigen. Also, the MTT assay showed acceptable relative cell viability of more than 85% in most cases, even by increasing the dose of the prepared nanostructures.
The Role of Lithospheric‐Deep Mantle Interactions on the Style and Stress Evolution of Arc‐Continent Collision
Publisher: American Geophysical Union (AGU)
Date: 11-2022
DOI: 10.1029/2022GC010386
Abstract: We investigate how the mechanical properties of intra‐oceanic arcs affect the collision style and associated stress‐strain evolution with buoyancy‐driven models of subduction that accurately reproduce the dynamic interaction of the lithosphere and mantle. We performed a series of simulations only varying the effective arc thickness as it controls the buoyancy of intra‐oceanic arcs. Our simulations spontaneously evolve into two contrasting styles of collision that are controlled by a 3% density contrast between the arc and the continental plate. In simulations with less buoyant arcs (15–31 km effective thickness), we observe arc‐transference to the overriding plate and slab‐anchoring and folding at the 660 km transition zone that result in fluctuations in the slab dip, strain‐stress regime, surface kinematics, and viscous dissipation. After slab‐folding occurs, the gravitational potential energy is dissipated in the form of lithospheric flow causing lithospheric extension in the overriding plate. Conversely, simulations with more buoyant arcs (32–35 km effective thickness) do not lead to arc‐transference and result in slab break‐off, which causes an asymptotic trend in surface kinematics, viscous dissipation and strain‐stress regime, and lithospheric extension in the overriding plate. The results of our numerical modeling highlight the importance of slab‐anchoring and folding in the 660 km transition zone on increasing the mechanical coupling of the subduction system.
Recent Advancements in aptamer-bioconjugates: Sharpening Stones for breast and prostate cancers targeting
Publisher: Elsevier BV
Date: 10-2019
Interpreting gravity, geoid, and topography for convection with temperature dependent viscosity: Application to surface features on Venus
Publisher: American Geophysical Union (AGU)
Date: 25-10-1995
DOI: 10.1029/95JE01622
Coupled layer construction for synthetic Hall effects in driven systems
Publisher: American Physical Society (APS)
Date: 17-10-2022
Continents, supercontinents, mantle thermal mixing, and mantle thermal isolation: Theory, numerical simulations, and laboratory experiments
Publisher: American Geophysical Union (AGU)
Date: 10-2011
DOI: 10.1029/2011GC003663
Tectonic and thermal evolution of Venus and the role of volatiles: Implications for understanding the terrestrial planets
Publisher: American Geophysical Union
Date: 2007
DOI: 10.1029/176GM05
ISMIP-HOM benchmark experiments using Underworld
Publisher: Copernicus GmbH
Date: 02-12-2022
Abstract: Abstract. Numerical models have become an indispensable tool for understanding and predicting the flow of ice sheets and glaciers. Here we present the full-Stokes software package Underworld to the glaciological community. The code is already well established in simulating complex geodynamic systems. Advantages for glaciology are that it provides a full-Stokes solution for elastic–viscous–plastic materials and includes mechanical anisotropy. Underworld uses a material point method to track the full history information of Lagrangian material points, of stratigraphic layers and of free surfaces. We show that Underworld successfully reproduces the results of other full-Stokes models for the benchmark experiments of the Ice Sheet Model Intercomparison Project for Higher-Order Models (ISMIP-HOM). Furthermore, we test finite-element meshes with different geometries and highlight the need to be able to adapt the finite-element grid to discontinuous interfaces between materials with strongly different properties, such as the ice–bedrock boundary.
Continental insulation, mantle cooling, and the surface area of oceans and continents
Publisher: Elsevier BV
Date: 15-06-2005
Correction to “Stagnant lid convection on Venus” by V. S. Solomatov and L.‐N. Moresi
Publisher: American Geophysical Union (AGU)
Date: 12-1997
DOI: 10.1029/97JE02281
MIL-125-based nanocarrier decorated with Palladium complex for targeted drug delivery
Publisher: Springer Science and Business Media LLC
Date: 15-07-2022
DOI: 10.1038/S41598-022-16058-W
Abstract: The aim of this work was to provide a novel approach to designing and synthesizing a nanocomposite with significant biocompatibility, biodegradability, and stability in biological microenvironments. Hence, the porous ultra-low-density materials, metal–organic frameworks (MOFs), have been considered and the MIL-125(Ti) has been chosen due to its distinctive characteristics such as great biocompatibility and good biodegradability immobilized on the surface of the reduced graphene oxide (rGO). Based on the results, the presence of transition metal complexes next to the drug not only can reinforce the stability of the drug on the structure by preparing π–π interaction between ligands and the drug but also can enhance the efficiency of the drug by preventing the spontaneous release. The effect of utilizing transition metal complex beside drug (Doxorubicin (DOX)) on the drug loading, drug release, and antibacterial activity of prepared nanocomposites on the P. aeruginosa and S. aureus as a model bacterium has been investigated and the results revealed that this theory leads to increasing about 200% in antibacterial activity. In addition, uptake, the release of the drug, and relative cell viabilities (in vitro and in vivo) of prepared nanomaterials and biomaterials have been discussed. Based on collected data, the median size of prepared nanocomposites was 156.2 nm, and their biological stability in PBS and DMEM + 10% FBS was screened and revealed that after 2.880 min, the nanocomposite’s size reached 242.3 and 516 nm respectively. The MTT results demonstrated that immobilizing PdL beside DOX leads to an increase of more than 15% in the cell viability. It is noticeable that the AST:ALT result of prepared nanocomposite was under 1.5.
Numerical Modeling of Earthquake Cycles Based On Navier‐Stokes Equations With Viscoelastic‐Plasticity Rheology
Publisher: American Geophysical Union (AGU)
Date: 09-2023
DOI: 10.1029/2023GC010872
Giant energy oscillations mediated by a quasiperiodically driven qubit
Publisher: American Physical Society (APS)
Date: 09-10-2023
The fingerprints of flexure in slab seismicity
Publisher: California Digital Library (CDL)
Date: 27-09-2019
Influence of lateral slab edge distance on plate velocity, trench velocity, and subduction partitioning
Publisher: American Geophysical Union (AGU)
Date: 27-10-2011
DOI: 10.1029/2011JB008535
Heat transport efficiency for stagnant lid convection with dislocation viscosity: Application to Mars and Venus
Publisher: American Geophysical Union (AGU)
Date: 06-1998
DOI: 10.1029/98JE01047
Evolution into the stagnant lid convection regime with a non‐Newtonian water ice rheology
Publisher: American Geophysical Union (AGU)
Date: 06-2004
DOI: 10.1029/2004GL019798
Underworld-GT applied to Guangdong, a tool to explore the geothermal potential of the crust
Publisher: Springer Science and Business Media LLC
Date: 30-01-2015
Crosslinked-polyvinyl alcohol-carboxymethyl cellulose/ZnO nanocomposite fibrous mats containing erythromycin (PVA-CMC/ZnO-EM): Fabrication, characterization and in-vitro release and anti-bacterial properties
Publisher: Elsevier BV
Date: 12-2019
DOI: 10.1016/J.IJBIOMAC.2019.09.060
Abstract: Recently, nanocomposite nanofibers have been extensively used for biomedical applications. It is expected that simultaneous incorporation of antibiotic drugs and ZnO nanoparticles into nanofiber resulted in providing the synergistic anti-bacterial effect. The main aim of the present study is to fabricate polyvinyl alcohol (PVA)/carboxymethyl cellulose (CMC)-ZnO nanocomposite fibrous mats containing erythromycin (EM) drug and crosslink them using 2% glutaraldehyde vapor and 3% AlCl
Green porous benzamide-like nanomembranes for hazardous cations detection, separation, and concentration adjustment
Publisher: Elsevier BV
Date: 02-2022
DOI: 10.1016/J.JHAZMAT.2021.127130
Abstract: Green biomaterials play a crucial role in the diagnosis and treatment of diseases as well as health-related problem-solving. Typically, biocompatibility, biodegradability, and mechanical strength are requirements centered on biomaterial engineering. However, in-hospital therapeutics require an elaborated synthesis of hybrid and complex nanomaterials capable of mimicking cellular behavior. Accumulation of hazardous cations like K
Australian Seismometers in Schools - Noise monitoring dashboard
Publisher: Front Matter
Date: 17-07-2020
DOI: 10.59350/WFTYB-VGS67
Influence of supercontinents on deep mantle flow
Publisher: Elsevier BV
Date: 06-2009
Effects of continental insulation and the partitioning of heat producing elements on the Earth's heat loss
Publisher: American Geophysical Union (AGU)
Date: 07-2006
DOI: 10.1029/2006GL026291
Dynamics of continental accretion
Publisher: Springer Science and Business Media LLC
Date: 23-03-2014
DOI: 10.1038/NATURE13033
Abstract: Subduction zones become congested when they try to consume buoyant, exotic crust. The accretionary mountain belts (orogens) that form at these convergent plate margins have been the principal sites of lateral continental growth through Earth's history. Modern ex les of accretionary margins are the North American Cordilleras and southwest Pacific subduction zones. The geologic record contains abundant accretionary orogens, such as the Tasmanides, along the eastern margin of the supercontinent Gondwana, and the Altaïdes, which formed on the southern margin of Laurasia. In modern and ancient ex les of long-lived accretionary orogens, the overriding plate is subjected to episodes of crustal extension and back-arc basin development, often related to subduction rollback and transient episodes of orogenesis and crustal shortening, coincident with accretion of exotic crust. Here we present three-dimensional dynamic models that show how accretionary margins evolve from the initial collision, through a period of plate margin instability, to re-establishment of a stable convergent margin. The models illustrate how significant curvature of the orogenic system develops, as well as the mechanism for tectonic escape of the back-arc region. The complexity of the morphology and the evolution of the system are caused by lateral rollback of a tightly arcuate trench migrating parallel to the plate boundary and orthogonally to the convergence direction. We find geological and geophysical evidence for this process in the Tasmanides of eastern Australia, and infer that this is a recurrent and global phenomenon.
Interactions of 3D mantle flow and continental lithosphere near passive margins
Publisher: Elsevier BV
Date: 03-2010
Global quieting of high-frequency seismic noise due to COVID-19 pandemic lockdown measures
Publisher: American Association for the Advancement of Science (AAAS)
Date: 11-09-2020
Abstract: Seismic background noise dramatically decreased as a result of lockdown measures in place for mitigating the spread of COVID-19.
Associations Between Household Socioeconomic Status, Car Ownership, Physical Activity, and Cardiorespiratory Fitness in South African Primary Schoolchildren Living in Marginalized Communities
Publisher: Human Kinetics
Date: 08-0100
Abstract: Background : Little is known whether physical activity (PA)-promoting environments are equally accessible to children with ergent socioeconomic status (SES) in low-/middle-income countries. The authors, therefore, examined whether South African children from poorer versus wealthier families living in marginalized communities differed in moderate to vigorous PA and cardiorespiratory fitness. We also tested associations between family car ownership and PA/cardiorespiratory fitness. Methods : Parents/guardians of 908 children (49% girls, mean age = 8.3 [1.4] y) completed a survey on household SES. PA was assessed via 7-day accelerometry, parental and child self-reports, and cardiorespiratory fitness with the 20-m shuttle run test. Results : Based on accelerometry, most children met current moderate to vigorous PA recommendations (≥60 min/d). About 73% of the children did not engage in structured physical education lessons. Whereas children of the lowest SES quintile accumulated higher levels of device-based moderate to vigorous PA, peers from the highest SES quintile engaged in more sedentary behaviors, but self-reported higher engagement in sports, dance, and moving games after school. Families’ car ownership was associated with higher parent/self-reported leisure-time PA. Conclusions : A deeper understanding is needed about why wealthier children are more sedentary, but simultaneously engage in more leisure-time PA. The fact that access to structural physical education is denied to most children is critical and needs to be addressed.
Small‐scale convection in the D″ layer
Publisher: American Geophysical Union (AGU)
Date: 2002
DOI: 10.1029/2000JB000063
Coupled influence of tectonics, climate, and surface processes on landscape evolution in southwestern North America
Publisher: Springer Science and Business Media LLC
Date: 08-2022
DOI: 10.1038/S41467-022-31903-2
Abstract: The Cenozoic landscape evolution in southwestern North America is ascribed to crustal isostasy, dynamic topography, or lithosphere tectonics, but their relative contributions remain controversial. Here we reconstruct landscape history since the late Eocene by investigating the interplay between mantle convection, lithosphere dynamics, climate, and surface processes using fully coupled four-dimensional numerical models. Our quantified depth-dependent strain rate and stress history within the lithosphere, under the influence of gravitational collapse and sub-lithospheric mantle flow, show that high gravitational potential energy of a mountain chain relative to a lower Colorado Plateau can explain extension directions and stress magnitudes in the belt of metamorphic core complexes during topographic collapse. Profound lithospheric weakening through heating and partial melting, following slab rollback, promoted this extensional collapse. Landscape evolution guided northeast drainage onto the Colorado Plateau during the late Eocene-late Oligocene, south-southwest drainage reversal during the late Oligocene-middle Miocene, and southwest drainage following the late Miocene.
India-Asia convergence driven by the subduction of the Greater Indian continent
Publisher: Springer Science and Business Media LLC
Date: 10-01-2010
DOI: 10.1038/NGEO725
Improving subduction interface implementation in dynamic numerical models
Publisher: Copernicus GmbH
Date: 24-01-2019
DOI: 10.5194/SE-2019-11
Abstract: Abstract. This study focuses on methodological issues related to dynamic subduction zone modelling. Numerical models often employ an entrained weak layer (WL approach) to facilitate decoupling between the subducting and overriding plates. In such a setup, the kinematics of the flow lead to width variations in the subduction interface. When a uniform-width interface is prescribed, a transient evolution of the interface thickness occurs, during which the volmetric flux along the interface profile establishes equilibrium. Width variations can exceed 4× during this stage, which may impact the effective strength of the interface, both through physical effects if the rheology is linear, and numerical effects if the fault becomes poorly resolved. This transient process induces strong sensitivity to model resolution, and may present a significant challenge to reproducibility. Developing more robust ways to model the subduction interface will enable fully dynamic models to address sensitive subduction-zone processes, such as metamorphism near the slab top. In this study we discuss a simple strategy aimed at improving the standard WL approach. By prescribing a variable thickness weak layer at the outset of the model, and by controlling the limits of the layer thickness during the model evolution, we find improved stability and resolution convergence of the models.
Quantum dots against SARS‐CoV ‐2: diagnostic and therapeutic potentials
Publisher: Wiley
Date: 04-02-2022
DOI: 10.1002/JCTB.7036
Abstract: The application of quantum dots (QDs) for detecting and treating various types of coronaviruses is very promising, as their low toxicity and high surface performance make them superior among other nanomaterials in conjugation with fluorescent probes they are promising semiconductor nanomaterials for the detection of various cellular processes and viral infections. In view of the successful results for inhibiting SARS‐CoV‐2, functional QDs could serve eminent role in the growth of safe nanotherapy for the cure of viral infections in the near future their large surface areas help bind numerous molecules post‐synthetically. Functionalized QDs with high functionality, targeted selectivity, stability and less cytotoxicity can be employed for highly sensitive co‐delivery and imaging/diagnosis. Besides, due to the importance of safety and toxicity issues, QDs prepared from plant sources (e.g. curcumin) are much more attractive, as they provide good biocompatibility and low toxicity. In this review, the recent developments pertaining to the diagnostic and inhibitory potentials of QDs against SARS‐CoV‐2 are deliberated including important challenges and future outlooks. © 2022 Society of Chemical Industry (SCI).
Non-Newtonian Stagnant Lid Convection and Magmatic Resur facing on Venus
Publisher: Elsevier BV
Date: 05-1999
Australian cities are quiet during lockdown. Earthquake scientists are making the most of it
Publisher: Front Matter
Date: 17-07-2020
DOI: 10.59350/9C35F-XX611
Erratum: Timing of deformation in the Norseman-Wiluna Belt, Yilgarn Craton, Western Australia (Precambrian Research (2003) 120 (219-239) PII S0301926803000408)
Publisher: Elsevier BV
Date: 03-2003
Comp. Psy. 101: The Psychology behind High Performance Computing
Publisher: Springer Berlin Heidelberg
Date: 2012
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