ORCID Profile
0000-0002-5479-1544
Current Organisation
The University of Canberra
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Financial Econometrics | Econometric And Statistical Methods | Econometrics | Applied Statistics
Publisher: Openventio Publishers
Date: 17-10-2016
DOI: 10.17140/SEMOJ-2-134
Publisher: Pan African Medical Journal
Date: 2017
Publisher: South African Medical Association NPC
Date: 02-2018
Publisher: SAGE Publications
Date: 21-08-2020
Abstract: Social isolation and sedentary behaviour are common in residential aged care facilities (also known as nursing homes or long-term care). Use of new technologies such as virtual and augmented reality are currently under investigation for their potential to provide exciting and engaging activities for older people in residential aged care facilities. However, there is limited evidence on whether these technologies can promote physical activity in a small group setting for people with cognitive impairment. Using mixed methods, we examined the use of a virtual cycling experience in a s le of 10 participants with cognitive impairment living in residential aged care facilities. In a randomised crossover design, participants engaged in a 25-minute, self-paced, facilitated seated virtual cycling experience and a time-matched seated physical activity session in groups of five. All participants completed a brief pre- and post-intervention mood questionnaire. Video analysis was used for both conditions to compare levels of environmental stimulation, apathy and engagement using both the Person–Environment Apathy Rating Scale and the Engagement of a Person with Dementia Scale. A thematic analysis of semi-structured interviews following the virtual cycling experience was also performed. No differences were observed between conditions for all outcomes except for environmental stimulation, where there was a lower response in the intervention than the control condition ( p = 0.032). This was primarily driven by lower scores for the virtual cycling experience than control in physical accessibility ( p = 0.012). Participants reported the virtual cycling experience to be immersive and challenging and reminisced about cycling earlier in life. The activity manager observed that the virtual cycling experience was an overall positive experience and emphasised benefits of safety screening and preparation prior to the activities. The findings of this study support the use of the virtual cycling experience as an immersive and engaging alternative to usual activities, which might encourage higher levels of physical activity in residential aged care facilities.
Publisher: SAGE Publications
Date: 08-2011
DOI: 10.2466/05.11.25.PMS.113.4.98-112
Abstract: The effect of sport stacking on auditory and visual attention in 32 Grade 3 children was examined using a randomised, cross-over design. Children were randomly assigned to a sport stacking ( n = 16) or arts/crafts group ( n = 16) with these activities performed over 3 wk. (12 30-min. sessions, 4 per week). This was followed by a 3-wk. wash-out period after which there was a cross-over and the 3-wk. intervention repeated, with the sports stacking group performing arts/crafts and the arts/crafts group performing sports stacking. Performance on the Integrated Visual and Auditory Continuous Performance Test, a measure of auditory and visual attention, was assessed before and after each of the 3-wk. interventions for each group. Comparisons indicated that sport stacking resulted in significant improvement in high demand function and fine motor regulation, while it caused a significant reduction in low demand function. Auditory and visual attention adaptations to sport stacking may be specific to the high demand nature of the task.
Publisher: Wiley
Date: 22-08-2014
DOI: 10.1002/AJHB.22605
Abstract: To determine the hypothalamic-pituitary-adrenal (HPA) axis and sympathoadrenal (SA) system response to repeated bouts of downhill running. Eleven active but untrained males (age: 19.7 ± 0.4 y VO2peak 47.8 ± 3.6 ml/kg/min) performed two 60 min bouts of downhill running (-13.5% gradient), separated by 14 days, at a speed eliciting 75% of their VO2peak on a level grade. Saliva s les were collected before (baseline), after, and every hour for 12 h and every 24 h for 6 days after each run. Salivary cortisol and α-amylase levels were measured as markers of the HPA axis and SA response, respectively. Results were analyzed using repeated measures ANOVA (12 h period: 2 × 14 24 h intervals 2 × 7, P ≤ 0.05) with Tukey post-hoc tests where appropriate. Paired s les t-tests were used to compare collapsed data vs. baseline measurements. There were no significant group × time interactions for cortisol or α-amylase for the hourly s les up to 12 h after each run, nor for the 24 h s les up to 6 days later. The 24 h s les for α-amylase showed a significant group effect between runs (Run 1: 69.77 ± 7.68 vs. Run 2: 92.19 ± 7.67 U/ml P = 0.04). Significant time effects were measured for both cortisol (decreased 2 h to 12 h post-run) and α-amylase (elevated immediately after, 1 h and 2 h post-run) (P < 0.001). The 24 h period group effect for salivary α-amylase suggested an adaptation in the sympathoadrenal system that may alter the systemic inflammatory response to exercise-induced muscle damage but may also reflect enhanced mucosal immunity.
Publisher: Springer Science and Business Media LLC
Date: 24-02-2016
Publisher: Canadian Science Publishing
Date: 04-2007
DOI: 10.1139/H06-106
Abstract: The purpose of this study was to examine changes in serum cytokines after repeated bouts of aerobically biased eccentric exercise. Six untrained males ran down a –13.5% treadmill grade for 60 min on two occasions (RUN1 and RUN2) at a speed equal to 75% of their VO 2 peak on a level grade runs were spaced 14 d apart. Serum was collected before, after, and every hour for 12 h, and every 24 h for 6 d. Cytokines were assessed using 17 multiplex bead technology (Bio-Rad). Creatine kinase (CK) and delayed-onset muscle soreness (DOMS) were assessed before and 24–120 h after. Results were analyzed using a repeated measures analysis of variance (p ≤ 0.05). All comparisons were between RUN1 and RUN2. CK and DOMS were significantly elevated after RUN1 compared with RUN2, indicative of a repeated bout effect. Regarding cytokines, during the initial 12 h period after RUN2, there was a 50% decrease in pro-inflammatory interleukin-6 (IL-6), a 10% decrease in pro-inflammatory macrophage chemotactic protein-1, and a 95% elevation in anti-inflammatory interleukin-10 (IL-10). Regarding 24 h periods, after RUN2 there was an 8% reduction in pro-inflammatory interleukin-8 (IL-8). However, pro-inflammatory macrophage inflammatory factor-1β (MIF-1β) was 18% higher during the 12 h after RUN2. The overall cytokine profile suggests a slight reduction in systemic inflammation after RUN2.
Publisher: Xia & He Publishing
Date: 03-2019
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 05-2015
Publisher: Academy of Science of South Africa
Date: 20-12-2004
DOI: 10.17159/2413-3108/2003/V15I3A223
Abstract: SA Sports Medicine Vol.15(3) 2003: 17-21
Publisher: Academy of Science of South Africa
Date: 05-10-2007
DOI: 10.17159/2078-516X/2007/V19I3A260
Abstract: Objective. A primary objective was to examine circulating neutrophil count after repeated bouts of downhill running. An additional aim was to determine creatine kinase (CK) levels during the initial 12 hours, after repeated DHRs. Design. Eleven healthy, untrained Caucasian males performed 2 x 60 min bouts of DHR (-13.5%), spaced 14 days apart, at a speed equal to 75% VO2max on a level grade. Blood was collected before, after, and every hour for 12 hours, and every 24 hours for 6 days. Absolute neutrophil count, CK, and delayed-onset muscle soreness (DOMS) were assessed. Results were analysed using repeated measures ANOVA (p
Publisher: Elsevier BV
Date: 05-2020
Publisher: BMJ
Date: 11-2010
Publisher: Informa UK Limited
Date: 04-05-2019
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 05-2011
Publisher: Frontiers Media SA
Date: 30-07-2018
Publisher: Academy of Science of South Africa
Date: 05-12-2007
DOI: 10.17159/2078-516X/2007/V19I5A654
Abstract: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality. As such, the disease places a significant burden on health care services. Although the pathogenesis of COPD is complex, progressive airflow limitation and a chronic inflammatory response are two hallmark characteristics of the disease. In addition, systemic manifestations such as peripheral muscle dysfunction have recently received considerable attention in the literature. Pulmonary rehabilitation is an evidence-based multidisciplinary intervention that has been shown to produce clinically relevant outcomes. One important component of rehabilitation is exercise. With the majority of COPD patients presenting with muscle weakness and exercise intolerance, the inclusion of resistance training into a pulmonary rehabilitation programme would seem appropriate. Compared with other exercise/training modalities only a small number of studies have investigated the effects of resistance training in COPD patients. Although further research is required to identify the optimal mode, intensity and frequency, it appears that resistance training may prove to be a valuable intervention for COPD patients enrolled in pulmonary rehabilitation programmes.
Publisher: Academy of Science of South Africa
Date: 2009
Publisher: Baishideng Publishing Group Inc.
Date: 10-02-2018
DOI: 10.5306/WJCO.V9.I1.1
Publisher: Human Kinetics
Date: 08-2015
Publisher: Springer Science and Business Media LLC
Date: 18-03-2016
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 05-2015
Publisher: Springer Science and Business Media LLC
Date: 28-02-2017
DOI: 10.1007/S00421-017-3565-5
Abstract: The effects of sleep deprivation on physical performance are well documented, but data on the consequence of sleep deprivation on recovery from exercise are limited. The aim was to compare cyclists' recovery from a single bout of high-intensity interval training (HIIT) after which they were given either a normal night of sleep (CON, 7.56 ± 0.63 h) or half of their usual time in bed (DEP, 3.83 ± 0.33 h). In this randomized cross-over intervention study, 16 trained male cyclists (age 32 ± 7 years), relative peak power output (PPO 4.6 ± 0.7 W kg PPO was reduced more 24 h after the HIIT session in the DEP (ΔPPO -0.22 ± 0.22 W kg One night of partial sleep deprivation impairs recovery from a single HIIT session in cyclists. Further research is needed to understand the mechanisms behind this observation.
Publisher: Termedia Sp. z.o.o.
Date: 2022
Publisher: MDPI AG
Date: 05-03-2023
DOI: 10.3390/NU15051289
Abstract: Aims: To evaluate the association between metabolically healthy overweight/obesity (MHO) status and longitudinal cognitive function while also considering the stability of the condition. Methods: In total, 2892 participants (mean age 60.7 (9.4) years) from Framingham Offspring Study completed health assessments every four years since 1971. Neuropsychological testing was repeated every four years starting from 1999 (Exam 7) to 2014 (Exam 9) (mean follow-up: 12.9 (3.5) years). Standardized neuropsychological tests were constructed into three factor scores (general cognitive performance, memory, processing speed/executive function). Healthy metabolic status was defined as the absence of all NCEP ATP III (2005) criteria (excluding waist circumference). MHO participants who scored positively for one or more of NCEP ATPIII parameters in the follow-up period were defined as unresilient MHO. Results: No significant difference on the change in cognitive function over time was observed between MHO and metabolically healthy normal weight (MHN) in iduals (all p 0.05). However, a lower processing speed/executive functioning scale score was observed in unresilient MHO participants compared to resilient MHO participants (β = −0.76 95% CI = −1.44, −0.08 p = 0.030). Conclusions: Retaining a healthy metabolic status over time represents a more important discriminant in shaping cognitive function compared to body weight alone.
Publisher: Informa UK Limited
Date: 03-2018
DOI: 10.2147/JIR.S155903
Publisher: Frontiers Media SA
Date: 24-09-2021
DOI: 10.3389/FPSYG.2021.738519
Abstract: To complement and enhance readiness-monitoring capability, the Acute Readiness Monitoring Scale (ARMS) was developed: a widely applicable, simple psychometric measure of perceived readiness. While this tool may have widespread utility in sport and military settings, it remains unknown if the ARMS demonstrates predictive and concurrent validity. Here, we investigated whether the ARMS is: (1) responsive to an acute manipulation of readiness using sleep deprivation, (2) relates to biological markers of readiness [cortisol/heart-rate variability (HRV)], and (3) predicts performance on a cognitive task. Thirty young adults (aged 23 ± 4 years 18 females) participated. All participants engaged in a 24-h sleep deprivation protocol. Participants completed the ARMS, biological measures of readiness (salivary cortisol, HRV), and cognitive performance measures (psychomotor vigilance task) before, immediately after, 24-, and 48-h post-sleep deprivation. All six of the ARMS subscales changed in response to sleep deprivation: scores on each subscale worsened (indicating reductions in perceived readiness) immediately after sleep deprivation, returning to baseline 24/48 h post. Lower perceived readiness was associated with reduced awakening responses in cortisol and predicted worse cognitive performance (slower reaction time). No relationship was observed between the ARMS and HRV, nor between any biological markers of readiness (cortisol/HRV) and cognitive performance. These data suggest that the ARMS may hold practical utility in detecting, or screening for, the wide range of deleterious effects caused by sleep deprivation may constitute a quick, cheap, and easily interpreted alternative to biological measures of readiness and may be used to monitor or mitigate potential underperformance on tasks requiring attention and vigilance.
Publisher: MDPI AG
Date: 21-02-2020
Abstract: Nutritional and ergogenic aid supplementation is prevalent within athletic or general fitness populations, and is only continuing to gain momentum. Taken in isolation or as a combination, amino acid (AA) supplementation has the potential to increase endurance performance among other benefits. L-Arginine (L-Arg) and L-Citrulline (L-Cit) are two AAs proposed to increase endothelial nitric oxide (NO) synthesis, with potential additional physiological benefits, and therefore may contribute to enhanced performance outcomes such as increased power output, or time to exhaustion. However, the appropriate dose for promoting physiological and performance benefits of these AAs, and their potential synergistic effects remains to be determined. Therefore, the aim of this review was to evaluate the varied concentrations used in the current literature, assess the effects of L-Arg and L-Cit in combination on physiological responses and endurance performance, and consider if there is a fundamental basis for providing these supplements in the form of a beverage. A total of six studies were considered eligible for the review which utilized a range of 3–8 g of the AA constituents. The findings support the notion that supplementing with a combination of L-Arg and L-Cit may increase NO production, enhance vasodilation, and therefore increase performance capacity in athletes. A beverage as a carrier for the two AAs is worth considering however, there remains limited research assessing these outcomes across a consistent range of concentrations in order to see their full potential.
Publisher: MDPI AG
Date: 17-08-2022
Abstract: Consumption of amino acids L-arginine (L-Arg) and L-citrulline (L-Cit) are purported to increase nitric oxide (NO) production and improve physical performance. Clinical trials have shown relatively more favorable outcomes than not after supplementing with L-Cit and combined L-Arg and L-Cit. However, in most studies, other active ingredients such as malate were included in the supplement. Therefore, the aim of this study was to determine the efficacy of consuming standalone L-Arg, L-Cit, and their combination (in the form of powder or beverage) on blood NO level and physical performance markers. A systematic review was undertaken following PRISMA 2020 guidelines (PROSPERO: CRD42021287530). Four electronic databases (PubMed, Ebscohost, Science Direct, and Google scholar) were used. An acute dose of 0.075 g/kg of L-Arg or 6 g L-Arg had no significant increase in NO biomarkers and physical performance markers (p 0.05). Consumption of 2.4 to 6 g/day of L-Cit over 7 to 16 days significantly increased NO level and physical performance markers (p 0.05). Combined L-Arg and L-Cit supplementation significantly increased circulating NO, improved performance, and reduced feelings of exertion (p 0.05). Standalone L-Cit and combined L-Arg with L-Cit consumed over several days effectively increases circulating NO and improves physical performance and feelings of exertion in recreationally active and well-trained athletes.
Publisher: Academy of Science of South Africa
Date: 20-12-2004
DOI: 10.17159/2413-3108/2004/V16I2A183
Abstract: Objectives. The human body initiates an acute phase response (APR) in response to a wide range of homeostatic disturbances. This complex series of reactions serves to activate repair processes and prevent ongoing tissue damage. An important aspect of the APR is the de novo synthesis of acute phase proteins (APP), many of which have not been thoroughly investigated. Main outcome measures. Alterations in CRP (C-reactive protein), C1est, C3, C4, C6, rheumatoid factor (RF) and Factor B were determined before and after an ultramarathon. Data were analysed using a one-way analysis of variance comparing values to pre-exercise levels. Significance was set at p 0.05. Design. Venepunctures were performed on athletes participating in an ultramarathon (90 km) 24 hours before, immediately post-exercise (IPE), and 3h, 24h and 72h after the race. Serum was stored at –80°C until analysed. CRP levels in serum were assessed using the N Latex CRP kit. The levels of circulating immune complexes (CIC) were determined using particle-enhanced nephelometry. Complement proteins C1est, C3, C4 and RF were measured using laser nephelometry. C6 and Factor B were determined by radial immunodiffusion. Results. CRP was significantly elevated IPE (58%), 3h post (77%), 24h post (87%) and 72h post (69%). Pre-race CRP levels were above the normative range (5.10 ± 3.08 mg/l), C6 was significantly elevated (p 0.05) at 24h post (7.8%) and 72h post (8.8%) exercise. Factor B was significantly elevated (p 0.05) at 72h post exercise (12.8%). RF was significantly elevated at 72h post exercise (6.7%). Conclusion. Significant increases in selected acutephase reactants occur several days after the exercise event. In addition, as indicated by elevated resting levels of CRP, the athletes began the race with some degree of inflammation, presumably as a result of the cumulative training and racing mileage in preparation for the ultramarathon. SA Sports Medicine Vol.16(2) 2004: 17-21
Publisher: Academy of Science of South Africa
Date: 20-12-2004
DOI: 10.17159/2413-3108/2004/V16I2A182
Abstract: Objective. To determine the effect of prolonged endurance exercise on the serum concentrations of eosinophil cationic protein (ECP), immunoglobulin E (IgE) and upper respiratory tract symptoms (URTS). Design. In 11 healthy, experienced volunteers (6 males, 5 females, age 43 ± 9.8 years) the serum concentrations of ECP and IgE were measured, 24 hours prior to projected finishing time, immediately post exercise (IPE), and 3 h, 24 h, and 72 h after an ultramarathon (90 km). Self-reported URTS were also recorded for 14 days after the race. ECP was measured using radioimmunoassay and IgE using the Alastat Microplate Total IgE kit. The after-exercise values were corrected for plasma volume changes, which were calculated from haematocrit and haemoglobin values. Serum concentrations of ECP and IgE were analysed using an analysis of variance (ANOVA) comparing values with before-exercise levels. Level of significance was set at p ≤ 0.05. Results. ECP was significantly elevated at 72 hours (+52%), whilst IgE was not significantly altered after the ultramarathon. There were no reported URTS for the 14 days after the race. Conclusion. The eosinophil is a pro-inflammatory leukocyte involved in bronchial hyperreactivity and allergic inflammation of the airways. IgE is associated with allergic diseases such as asthma and rhinitis. Serum ECP is a sensitive marker of eosinophil activation. The result provides evidence for the non-allergic activation of blood eosinophils during prolonged endurance exercise. Whether this indicates exercise or environmentally induced airway inflammation, or a role for ECP in muscle /tissue repair, are hypotheses that require additional research. SA Sports Medicine Vol.16(2) 2004: 12-16
Publisher: Human Kinetics
Date: 05-2021
Abstract: Purpose : The risk of exercise-induced endotoxemia is increased in the heat and is primarily attributable to changes in gut permeability resulting in the translocation of lipopolysaccharides (LPS) into the circulation. The purpose of this study was to quantify the acute changes in gut permeability and LPS translocation during submaximal continuous and high-intensity interval exercise under heat stress. Methods : A total of 12 well-trained male runners (age 37 [7] y, maximal oxygen uptake [VO 2 max] 61.0 [6.8] mL·min −1 ·kg −1 ) undertook 2 treadmill runs of 2 × 15-minutes at 60% and 75% VO 2 max and up to 8 × 1-minutes at 95% VO 2 max in HOT (34°C, 68% relative humidity) and COOL (18°C, 57% relative humidity) conditions. Venous blood s les were collected at the baseline, following each running intensity, and 1 hour postexercise. Blood s les were analyzed for markers of intestinal permeability (LPS, LPS binding protein, and intestinal fatty acid–binding protein). Results : The increase in LPS binding protein following each exercise intensity in the HOT condition was 4% (5.3 μg·mL −1 , 2.4–8.4 mean, 95% confidence interval, P .001), 32% (4.6 μg·mL −1 , 1.8–7.4 P = .002), and 30% (3.0 μg·mL −1 , 0.03–5.9 P = .047) greater than in the COOL condition. LPS was 69% higher than baseline following running at 75% VO 2 max in the HOT condition (0.2 endotoxin units·mL −1 , 0.1–0.4 P = .011). Intestinal fatty acid–binding protein increased 43% (2.1 ng·mL −1 , 0.1–4.2 P = .04) 1 hour postexercise in HOT compared with the COOL condition. Conclusions : Small increases in LPS concentration during exercise in the heat and subsequent increases in intestinal fatty acid–binding protein and LPS binding protein indicate a capacity to tolerate acute, transient intestinal disturbance in well-trained endurance runners.
Publisher: MDPI AG
Date: 04-08-2021
Abstract: The proportion of adults living with hypertension increases significantly with advancing age. It is therefore important to consider how health and vitality can be maintained by the aging population until end of life. A primary risk factor for the progression of cardiovascular diseases (CVD) is hypertension, so exploring the factors and processes central to this burden of disease is essential for healthy aging. A loss of skeletal muscle quantity and quality is characteristic in normal aging, with a reduction of vasodilatory capacity caused by endothelial dysfunction, and subsequent increase in peripheral resistance and risk for hypertension. Reactive Oxygen and Nitrogen Species (RONS) encompass the reactive derivatives of NO and superoxide, which are continuously generated in contracting skeletal muscle and are essential mediators for cellular metabolism. They act together as intra and intercellular messengers, gene expression regulators, and induce programmed cell death. In excessive amounts RONS can inflict damage to endothelial and skeletal muscle cells, alter signaling pathways or prematurely promote stress responses and potentially speed up the aging process. The age-related increase in RONS by skeletal muscle and endothelial mitochondria leads to impaired production of NO, resulting in vascular changes and endothelial dysfunction. Changes in vascular morphology is an early occurrence in the etiology of CVDs and, while this is also a normal characteristic of aging, whether it is a cause or a consequence of aging in hypertension remains unclear. This review serves to focus on the roles and mechanisms of biological processes central to hypertension and CVD, with a specific focus on the effects of aging muscle and RONS production, as well as the influence of established and more novel interventions to mediate the increasing risk for hypertension and CVD and improve health outcomes as we age.
Publisher: MDPI AG
Date: 15-05-2019
Abstract: Background and Objectives: There is confusion as to which component of the Opuntia spp. cacti has demonstrated anti-hyperglycemic effects or anti-diabetic properties. It is important to clarify these health benefits due to the increasing need for prevention and treatment of chronic diseases. The aim of this review is to identify the effects of Opuntia spp. cacti consumption on biomedical measures glucose and insulin with consideration of its’ components fruit, leaf and combined or unidentified Opuntia spp. products. Materials and Methods: Prior to commencing the searches, this systematic review was registered with PROSPERO (CRD42018108765). Following the PRISMA 2009 guidelines, six electronic databases (Food Science and Technology Abstracts (EBSCO), Medline, Scopus, CINAHL, Web of Science and Cochrane) were searched for articles investigating the effect of Opuntia spp. consumption on glucose and insulin in humans. Results: Initially, 335 articles were sourced and filtered by exclusion criteria (human interventions, control trials and articles published in English) resulting in 20 relevant articles. The included studies were characterized by such plant components as fruit (n = 4), cladode (n = 12), and other Opuntia spp. products (n = 4), further separated by clinical populations (‘healthy’, hyperlipidemic, hypercholesterolemic, Type 2 Diabetes Mellitus). The findings of this review indicate variations in effects between cacti components and products. Cladode and select Opuntia spp. products predominately demonstrated significant reductions in serum glucose and insulin, indicating potential as a functional food candidate. Prickly Pear fruit was predominately reported to have no significant effects on glucose or insulin. The quality of evidence appeared to vary based on the type of Opuntia spp. product used. Studies that used specifically the fruit or cladode had high risk of bias, whereas studies which used combined Opuntia spp. products had a lower risk of bias. Numerous mechanisms of action were proposed where positive findings were reported, with emphasis on dualistic glucose-dependent and independent actions, however, mechanisms require further elucidation. Conclusion: Currently, there is a lack of evidence to support the recommendation of using Opuntia spp. fruit products as an alternative or complementary therapy in the reduction of risk or management of Type 2 Diabetes Mellitus. The Cladode does however show promise in potential glucose-lowering effects which warrant further investigation.
Publisher: Springer Science and Business Media LLC
Date: 22-11-2020
DOI: 10.1007/S11130-019-00771-5
Abstract: The green tea amino acid, L-theanine (L-THE) is associated with several health benefits, including improvements in mood, cognition and a reduction of stress and anxiety-like symptoms. This systematic review evaluated the effect of pure L-THE intake, in the form of orally administered nutritional supplements, on stress responses and anxiety levels in human randomised controlled trials. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist, 9 peer-reviewed journal articles were identified where L-THE as a supplement was compared to a control. Our findings suggest that supplementation of 200-400 mg/day of L-THE may assist in the reduction of stress and anxiety in people exposed to stressful conditions. Despite this finding, longer-term and larger cohort clinical studies, including those where L-THE is incorporated into the diet regularly, are needed to clinically justify the use of L-THE as a therapeutic agent to reduce stress and anxiety in people exposed to stressful conditions.
Publisher: MDPI AG
Date: 21-06-2016
Publisher: MDPI AG
Date: 03-06-2021
Abstract: Functional beverages can be a valuable component of the human diet with the ability to not only provide essential hydration but to deliver important bioactive compounds that can contribute to chronic disease treatment and prevention. One area of the functional beverage market that has seen an increase in demand in recent years are beverages that promote relaxation and sleep. Sleep is an essential biological process, with optimal sleep being defined as one of adequate duration, quality and timing. It is regulated by a number of neurotransmitters which are, in turn, regulated by dietary intake of essential bioactive compounds. This narrative review aimed to evaluate the latest evidence of the sleep promoting properties of a selection of bioactive compounds (such as L-theanine and L-tryptophan) for the development of a functional beverage to improve sleep quality and the effectiveness of traditional sleep promoting beverages (such as milk and chamomile). Overall, the bioactive compounds identified in this review, play essential roles in the synthesis and regulation of important neurotransmitters involved in the sleep-wake cycle. There is also significant potential for their inclusion in a number of functional beverages as the main ingredient on their own or in combination. Future studies should consider dosage interactions with the beverage matrix, medications and other nutraceuticals bioavailability during storage and following ingestion as well as the sensory profile of the developed beverages, among others, when determining their effectiveness in a functional beverage to improve sleep quality.
Publisher: Index Copernicus
Date: 08-10-2015
Publisher: MDPI AG
Date: 30-05-2016
Publisher: Elsevier BV
Date: 07-2019
DOI: 10.1016/J.AUTNEU.2019.03.002
Abstract: This study evaluated the associations between cardiac autonomic nervous system (ANS) activity and cardiometabolic disease (CMD) risk factors among black South African children. The participants included 34 black South African children (11.85 ± 0.89 y). CMD risk factors included waist circumference (WC), hip circumference (HC), body mass index z-score (BMI z-score), blood pressure (SBP, DBP), total cholesterol (TC), high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL), fasting glucose (FG), fasting insulin (FINS), and vessel stiffness index (SI). Heart rate variability was used to quantify cardiac ANS activity. lnRMSSD, pNN50 and lnSD1 were inversely associated with FINS (r = -0.33, p = 0.05 r = -0.36, p = 0.03 r = -0.41, p = 0.01), WC (r = -0.45, p = 0.01 r = -0.39, p = 0.02 r = -0.45, p = 0.01), and HC (r = -0.41, p = 0.01 r = -0.36, p = 0.03 r = -0.43, p = 0.01). HDL was positively associated with lnRMSSD (r = 0.37 p = 0.03) and lnSD1 (r = 0.37 p = 0.03) while, LDL was negatively associated with HF (r = -0.41 p = 0.01). Regression analysis identified WC as the primary predictor for parasympathetic modulation in time domain (lnRMSSD: r2 = 0.21, p = 0.01 pNN50: r2 = 0.18, p = 0.01) and non-linear domain (lnSD1: r2 = 0.21, p = 0.01). Elevated resting parasympathetic activity in children is associated with lower CMD risk factors and an elevation in the protective HDL.
Publisher: Springer Science and Business Media LLC
Date: 30-08-2018
DOI: 10.1038/S41430-018-0295-7
Abstract: Humans appear to have innate energy regulation mechanisms that manifest in sensations of satiation during a meal and satiety post ingestion. Interactions between these mechanisms and the macronutrient profile of their contemporary food environment could be responsible for the dysregulation of this mechanism, resulting in a higher energy intake. The aim of this systematic review was to determine the impact of dietary fibre and fat both in isolation and combination on satiation and satiety. A systematic review of the literature was undertaken, from inception until end December 2017, in accordance with the PRISMA guidelines, in: Scopus, Food Science and Tech, CINAHL, and Medline databases. The search strategy was limited to articles in English language, published in peer-reviewed journals and human studies. Studies were selected based on inclusion/exclusion criteria. A total of 1490 studies were found initially using the selected search terms that were reduced to 12 studies suitable for inclusion. Following on from this, a meta-analysis was also conducted to determine any satiety effects from any potential interaction between dietary fat and fibre on satiety, no significant effects were found. Owing to high energy density, fat (per kJ) had a weak effect on satiation as determined by the effect per gram for each unit of energy. The addition of fibre theoretically improves satiety by slowing the absorption of various nutrients including fat, although the meta-analysis as part of this review was unable to demonstrate an effect, perhaps reflecting a lack of sensitivity in research design. The potential to improve satiation and satiety responses by consuming fat together with carbohydrates containing fibre warrants further investigation.
Publisher: Wiley
Date: 05-2017
Publisher: Oxford University Press (OUP)
Date: 11-2018
Publisher: BMJ
Date: 10-2006
Publisher: Walter de Gruyter GmbH
Date: 2013
Publisher: SAGE Publications
Date: 2019
Abstract: The prevalence of cardiovascular disease (CVD) is rising worldwide, remaining the major cause of death in developed countries. Polyphenols have been shown to have cardioprotective properties however, their impact on iron bioavailability and potential impact on other aspects of health is unclear. A systematic review was undertaken to evaluate the current status of the relationship between habitual polyphenol consumption, iron status, and circulating biomarkers of CVD. Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2009 guidelines, searches were performed across 5 electronic databases (PubMed, Cochrane Library, Scopus, Web of Science, and CINAHL) to identify randomized controlled trials which investigated the effects of polyphenol consumption on inflammatory markers, serum lipid profile, and iron absorption and bioavailability. In total, 1174 records were identified, with only 7 studies meeting the inclusion criteria. The selected studies involved 133 participants and used a variety of foods and supplements, including olive oil and cherries, rich in polyphenols including hydroxytyrosol, quercetin, and resveratrol, as well as catechin enriched drinks. The duration of the studies ranged from between 56 and 145 days, with total polyphenolic content of the food items and supplements ranging from 45 to 1015 mg (per 100 g). Polyphenols did not appear to interfere with iron status, and most studies reported improvements in inflammatory markers and lipid profile. While these results are promising, the limited number of studies and considerable heterogeneity across the interventions support the need for more extensive trials assessing the relationship between polyphenol intake, iron bioavailability, and CVD risk.
Publisher: Springer Science and Business Media LLC
Date: 23-04-2019
Publisher: Walter de Gruyter GmbH
Date: 29-09-2021
Abstract: Oral mucositis is a debilitating oncology treatment side effect, with honey identified as a viable management option due to established wound-healing abilities. However, effects of saliva on properties attributed to honey’s wound-healing abilities is unknown. Therefore, this study aimed to identify interactions between saliva, and antioxidant characteristics and pH of honey. Saliva was collected from 15 healthy participants (Females n=9 mean age=34.1 ± 11.2 years). Centrifuged salivary supernatant, whole saliva, and water were independently used to dilute commercial Australian honeys (n=42). Antioxidant characteristics (DPPH and FRAP) and pH of diluted honeys were analysed, and differences between dilution conditions were determined. Honey and saliva dilutions increased antioxidant characteristics compared to water, and addition of honey to saliva reduced pH compared with saliva alone. There were significant differences between dilutions for FRAP and pH, and water and salivary conditions for DPPH (p .001). No difference was observed between salivary conditions for DPPH (p=0.931), suggesting smaller cells remaining in the supernatant possess antioxidant abilities. However, differences observed for FRAP suggest precipitable molecules, including epithelial and food debris, could provide additional antioxidant power. The addition of saliva to honey may support properties attributed to honey’s wound-healing abilities and should be considered in the context of oral mucositis management.
Publisher: Elsevier BV
Date: 08-2019
DOI: 10.1016/J.JSAMS.2019.03.013
Abstract: To examine the effects of a probiotic protocol on the incidence and severity of respiratory and gastrointestinal infections in elite rugby union athletes across an international competition season. Associations were also investigated between salivary biomarkers of stress (cortisol, alpha-amylase) and mucosal immunity (secretory(s)-IgA). A double-blind RCT was conducted over 27-weeks, ided into three stages: (1) control period (2) domestic competition and (3) international competition. Athletes were assigned a probiotic (n = 9) or placebo (n = 10) supplement. Ultrabiotic 60™ or placebo was taken with food twice daily for 17 weeks and SB Floractiv™ 250 mg added twice daily during stage three. Five infections were diagnosed by the team sports physician across the 27-weeks, three within the intervention period in athletes randomised to the placebo group. No significant group x time interaction effects for salivary cortisol, alpha-amylase or s-IgA were identified over the 27-week time period, although a significant main effect for group and time was identified for salivary cortisol, alpha-amylase, and s-IgA (p < 0.05 for all). When considering stage, significant differences were identified in stage one with s-IgA lower in the probiotic group (p = 0.015). In stage two and three, salivary cortisol was higher in the probiotic group (p = 0.016 and p = 0.001 respectively), and salivary alpha-amylase was higher in the probiotic group in stage three (p = 0.007). The probiotic protocol used in this study was associated with an increase in salivary alpha-amylase supporting its possible role as a host defence peptide.
Publisher: Public Library of Science (PLoS)
Date: 20-12-2022
DOI: 10.1371/JOURNAL.PONE.0279307
Abstract: This study investigated the effects of acute, pre-exercise, hydrogen rich water (HRW) ingestion on running time to exhaustion at maximal aerobic speed in trained track and field runners. Twenty-four, male runners aged 17.5 ± 1.8 years, with body mass index = 21.0 ± 1.3 kg⋅m -2 , and maximal oxygen uptake = 55.0 ± 4.6 ml⋅kg -1 ⋅min -1 (mean ± standard deviation) participated in this randomized, double-blind, placebo-controlled crossover study. All runners ingested 1260 ml of HRW which was ided into four doses and taken at 120 min (420 ml), 60 min (420 ml), 30 min (210 ml), and 10 min (210 ml) prior to exercise. The running protocol consisted of three phases: warm-up performed at 10 km⋅h -1 for 3 min, followed by a transition phase performed at an in idually determined speed (10 km⋅h -1 + maximal aerobic speed)/2 for 1 min, and finally the third phase performed at in idual maximal aerobic speed until exhaustion. Time to exhaustion, cardiorespiratory variables, and post-exercise blood lactate concentration were measured. When running to exhaustion at maximal aerobic speed, compared with placebo, HRW had no significant effects on the following variables: time to exhaustion (217 ± 49 and 227 ± 53 s, p = 0.20), post-exercise blood lactate concentration (9.9 ± 2.2 and 10.1 ± 2.0 mmol⋅L -1 , p = 0.42), maximal heart rate (186 ± 9 and 186 ± 9 beats⋅min -1 , p = 0.80), and oxygen uptake (53.1 ± 4.5 and 52.2 ± 4.7 ml⋅kg -1 ⋅min -1 , p = 0.33). No variable assessed as a candidate moderator was significantly correlated with time to exhaustion (Spearman’s correlation coefficients ranged from −0.28 to 0.30, all p ≥ 0.16). Pre-exercise administration of 1260 ml of HRW showed no ergogenic effect on running performance to exhaustion at maximal aerobic speed in trained track and field runners.
Publisher: Frontiers Media SA
Date: 06-08-2019
Publisher: MDPI AG
Date: 16-11-2019
Abstract: Decreased physical activity (PA) is a global concern contributing to the rise in cardiometabolic diseases. One potential mechanism linking insufficient PA and poor health is dysregulated autonomic nervous system (ANS) activity. This relationship is established in adults and PA recommendations, with specific exercise prescription guidelines, have been proposed to overcome this societal health burden. However, research on the benefits and underlying mechanisms of exercise on ANS activity in children years old is limited. This review aimed to describe the optimal exercise “dose” and potential mechanisms of action that exercise may pose on enhancing child ANS activity, represented by heart rate variability (HRV). PubMed, Web of Science and Google Scholar were searched for articles examining the influence of exercise on child HRV. Various exercise duration and frequency combinations appear to improve HRV indices, primarily those representing parasympathetic influence. Furthermore, both aerobic and resistance training benefit HRV through potentially different mechanisms with intensity proposed to be important for exercise prescription. Findings indicate that exercise is a crucial lifestyle modification with protective and therapeutic effects on cardiometabolic health associated with improvements in child ANS activity. Exercise programming must consider the various components including mode, intensity and population characteristics to optimize ANS health.
Publisher: Elsevier BV
Date: 2019
Publisher: Cambridge University Press (CUP)
Date: 13-03-2018
DOI: 10.1017/S0144686X18000235
Abstract: Despite the benefits of exercise, a large percentage of the older population in South Africa continue to lead sedentary lifestyles. This study aimed to determine the effects of a structured group exercise programme on functional fitness of older persons living in old-age homes. A quasi-experimental design was used to compare the effects of a 12-week group exercise programme. Twenty participants each were selected from five old-age homes. Participants were randomly allocated into either an experimental group or a comparison group at each site. The experimental group participated in the exercise intervention three times weekly, while the comparison group received the same intervention twice weekly for 12 weeks. The intervention programme included warm-up, balance, endurance, resistance and cool-down components. Assessments of upper and lower body strength and flexibility, aerobic endurance, agility and balance were conducted before and after the intervention programme using the Senior Functional Test. Comparisons of baseline and post-intervention measures showed greater improvements in upper and lower body strength and flexibility, as well as aerobic endurance capacity ( p 0.05). Training frequency revealed no significant difference in functional fitness measures between both groups following the 12-week intervention programme. Twelve weeks of multifaceted group exercise training, at least twice a week, can be used as an effective strategy to promote functional fitness in this population.
Publisher: Hindawi Limited
Date: 04-02-2017
DOI: 10.1111/ARE.13270
Publisher: Springer Science and Business Media LLC
Date: 06-02-2020
Publisher: Academy of Science of South Africa
Date: 10-11-2022
DOI: 10.17159/2078-516X/2022/V34I1A14018
Abstract: Background: The ingestion of dietary supplements and beverages is prevalent in soccer, at the amateur and professional level. The absence of professional advice at non-professional level makes amateur soccer players susceptible to ingesting unsafe supplements. Objectives: To determine the knowledge, attitudes and practices of ABC Motsepe League (semi-professional) players in KwaZulu-Natal regarding the use of dietary supplements and beverages. Methods: Three hundred and forty-three soccer players participated in a cross-sectional study. Knowledge, attitudes and practices were determined using a questionnaire. Researchers visited twelve teams. On the day of the visit to each team, information sheets and questionnaires were given to participants. Questionnaires were collected immediately following completion. Descriptive statistics were used, including means and standard deviations, where applicable. Inferential statistics, Chi-square and binomial tests were used to analyse the results. Statistical significance was set at p 0.05. Results: Sports beverages were the most recommended and commonly used, followed by energy beverages. Dietary supplements were the least-known used. Participants used beverages and dietary supplements to assist in providing more energy (67%), improve health (65%) and improve performance (55%) (p .001). Seventy-three percent of participants lacked knowledge about the anti-doping policy (p .001), with 87% having never attended a workshop on the safe use of supplements and beverages, or anti-doping awareness c aigns (p .001). Thirty-eight percent had not heard of the South African Institute for Drug-Free Sport (SAIDS), and 84% were not familiar with the yearly updated World Anti-Doping Agency’s (WADA) prohibited list (p .001). Of the 59% who did not take dietary supplements or beverages, 75% had insufficient information regarding them (p .001), 66% indicated that dietary supplements and beverages were costly (p=0.001), and 55% indicated they did not need dietary supplements and beverages (p=0.32). Conclusion: There is a need for an educational programme on the safe use of dietary supplements, and sports and energy beverages among KwaZulu-Natal semi-professional soccer players.
Publisher: Frontiers Media SA
Date: 23-11-2018
Publisher: Human Kinetics
Date: 09-2020
Abstract: Purpose : Hydrogen-rich water (HRW) has been shown to have an antifatigue effect. This study assessed up-hill running performance, as well as physiological and perceptual responses after supplementation with 1680 mL HRW between 24 h and 40 min before running, in athletes of heterogeneous running ability. Methods : Sixteen males (mean [SD] age 31.6 [8.6] y, VO 2 max 57.2 [8.9] mL·kg −1 ·min −1 , body fat 13.4% [4.4%]) participated in this study. Using a randomized, double-blind, placebo-controlled crossover design, participants consumed either HRW or placebo prior to performing two 4.2-km up-hill races separated by a week. Race time (RT), average race heart rate, and immediately postrace rating of perceived exertion were assessed. Results : After analysis of data for all runners, HRW effect was unclear (−10 to 7 s, 90% confidence interval) for RT, likely trivial for heart rate (−2 to 3 beats·min −1 ), and likely trivial for postrace rating of perceived exertion (−0.1 to 1.0). A possible negative correlation was found between RT differences and average RT ( r = −.79 to −.15). HRW for the 4 slowest runners (RT = 1490 [91] s) likely improved the RT (−36 to −3 s), whereas for the 4 fastest runners (RT = 1069 [53] s) the performance effect of HRW was unclear (−10 to 26 s). Conclusions : HRW intake had an unclear antifatigue effect on performance in terms of mean group values. However, it appears that the magnitude of the antifatigue effect of HRW on performance depends on in idual running ability.
Publisher: Springer Science and Business Media LLC
Date: 10-08-2020
Publisher: Xia & He Publishing
Date: 12-2017
Publisher: Informa UK Limited
Date: 05-01-2016
Publisher: Xia & He Publishing
Date: 14-08-2020
Publisher: Academy of Science of South Africa
Date: 03-02-2009
DOI: 10.17159/2413-3108/2006/V18I2A243
Abstract: The prevalence of asthma and airway hyperresponsiveness (AHR) in highly trained endurance athletes is rising. The type of training (i.e. endurance, or speed and power) seems to influence the airway symptoms. High-intensity exercise and training might contribute to the development of asthma or AHR in athletes previously unaffected by these airway disorders. Repeated hyperventilation of unconditioned air, as well as air containing irritants and/or allergens has been suggested to cause thermal, mechanical, or osmotic airway trauma resulting in damage to the airway epithelium. Subsequent airway inflammatory responses may be responsible for the development of atopy-related symptoms in endurance athletes such as those observed in asthma and AHR. Eosinophils and neutrophils are the inflammatory cells that have been frequently observed to be elevated in the airways of endurance athletes. The trafficking of these cells to the airways may possibly be regulated by TH2 cytokines that are expressed in the airways in response to epithelial cell damage. In addition, these airway inflammatory responses may lead to airway remodelling similar to that which occurs in asthma. The effect of the exercise challenge itself may initiate airway atopy-related and inflammatory responses in endurance athletes. While the literature seems to support the role of local airway conditions and/or events in inducing atopy-related symptoms in athletes, it is proposed that alterations in the hormonal and/or cytokine milieu with intense competition and/or training may also play a role. South African Journal of Sports Medicine Vol. 18 (2) 2006: pp. 46-51
Publisher: Elsevier BV
Date: 12-2018
DOI: 10.1016/J.JPEDS.2018.07.067
Abstract: To explore the impact of short-term exercise of varying intensity on traditional risk factors for cardiometabolic disease. A total of 109 children (mean age, 11.1 ± 0.8 years) were conveniently assigned to 5 weeks of moderate-intensity continuous training (MICT n = 29) set at 65%-70% of maximum heart rate, high-intensity interval training (HIIT n = 29 >80% maximum heart rate), combined training (HIIT + MICT n = 27), or no training (control n = 24). Two-way ANOVA (group × time) was used to evaluate the effects of training on all cardiometabolic disease risk factors. Effect sizes were calculated to assess the magnitude of difference. MICT, HIIT, and HIIT + MICT were associated with significantly improved resting heart rate (effect size, -0.4, -1.1, and -1.1, respectively P < .0001), fasting glucose (effect size, -0.6, -0.9, and -0.1, respectively P = .0004), peak oxygen consumption (effect size, 0.5, 0.9, and 0.5, respectively P < .0001), and c-reactive protein (effect size, -0.2, -1.0, and -0.5, respectively P = .0016). HIIT + MICT was significantly associated with reduced waist circumference (-5.4% P < .0001) and waist-to-hip ratio (-2.5% P < .0002) compared with MICT (7.0% and 6.3%, respectively) and HIIT (-0.5% and -1.3%, respectively). Short-term HIIT and MICT interventions are useful for improving cardiometabolic health in children. HIIT + MICT may provide superior reductions in central obesity indicators.
Publisher: Springer Science and Business Media LLC
Date: 20-08-2020
DOI: 10.1186/S12885-020-07295-1
Abstract: Cardiovascular disease (CVD) remains the largest cause of death in breast cancer survivors. The aim of this study was to explore the impact of exercise intensity on aerobic fitness and autonomic cardiac regulation (heart rate variability (HRV)) and salivary biomarkers of the stress systems (HPA-axis, cortisol sympathetic nervous system, α-amylase) and mucosal immunity (secretory(s)-IgA), markers of increased risk of CVD in breast cancer survivors. Participants were randomly assigned to 1) high intensity interval training (HIIT) 2) moderate-intensity, continuous aerobic training (CMIT) or 3) a wait-list control (CON) for a 12-week (36 session) stationary cycling intervention. Cardiorespiratory fitness (VO 2peak ), resting HRV and salivary biomarkers were measured at baseline 2–4 d pre-intervention and 2–4 d post the last exercise session. Seventeen participants were included in this study (62 ± 8 years, HIIT n = 6, CMIT n = 5, CON n = 6). A significant improvement ( p ≤ 0.05) was observed for VO 2peak in the HIIT group 19.3% (B = 3.98, 95%CI = [1.89 4.02]) and a non-significant increase in the CMIT group 5.6% (B = 1.96, 95%CI = [− 0.11 4.03]), compared with a 2.6% (B = − 0.64, 95%CI = [− 2.10 0.82]) decrease in the CON group. Post intervention improvements in HRV markers of vagal activity (log (ln)LF/HF, LnRMSSD) and sympathetic nervous system (α-amylase waking response) occurred for in iduals exhibiting outlying ( 95% CI) levels at baseline compared to general population. High intensity interval training improved cardiovascular fitness in breast cancer survivors and improved cardiac regulation, and sympathetic nervous system (stress) responses in some in iduals. High-intensity interval training was safe and effective for breast cancer survivors to participate in with promising results as a time efficient intensity to improve physical health and stress, reducing CVD risk. This pilot study was retrospectively registered through the Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12620000684921 .
Publisher: Elsevier BV
Date: 11-2018
DOI: 10.1016/J.FOODRES.2018.07.019
Abstract: There is a growing body of evidence implicating the gut 'microbiome' role in overall human health. Bacterial species belonging to the genera Lactobacillus and Bifidobacterium are generally considered to be beneficial and are commonly used in probiotic applications, whereas increases in some genera including Clostridum, Eubacterium and Bacteroides are implicated in negative health outcomes. Dietary polyphenols are bioactive compounds that have been found to increase the numbers of beneficial bacteria and antimicrobial actions against pathogenic bacteria, however most studies have been conducted in animal models or in-vitro colonic models. The aim of this systematic review was to provide an overview of recent trials on the effect of dietary grape and red wine polyphenols on the gut microbiota in humans. Following PRISMA guidelines, a systematic review was conducted of electronic databases (PubMed, CINAHL, Cochrane Library, Wed of Science and Scopus) to identify human intervention trials examining the effect of grape or wine polyphenols on gut microbiota. Seven trials met the inclusion criteria. One study looked at changes in gut microbiota following the ingestion of de-alcoholised red wine or red wine, and six studies referred to gut microbiota as intermediates in formation of phenolic metabolites. All studies confirmed that ingested polyphenols from grape and red wine, were modulated by gut microbiota, increasing numbers of polyphenolic metabolites which were found in blood, urine, ileal fluid and faeces. Intake of polyphenols derived from grape and red wine can modulate gut microbiota and contribute to beneficial microbial ecology that can enhance human health benefits. Additionally, grape and red wine polyphenols were modulated by the gut microbiota and there is a potential for a two-way relationship between the gut microbiota and polyphenolic compounds. Nevertheless, additional research is required to fully understand the complex relationship between gut microbiota and dietary polyphenols before any health claims can be made in relation to human health.
Publisher: Springer Science and Business Media LLC
Date: 05-12-2018
DOI: 10.1007/S00432-017-2552-X
Abstract: There is an increasing body of evidence underpinning high-intensity exercise as an effective and time-efficient intervention for improving health in cancer survivors. The aim of this study was to, (1) evaluate the efficacy and (2) the safety of high-intensity exercise interventions in improving selected health outcomes in cancer survivors. Design Systematic review. Data sources Google Scholar and EBSCO, CINAHL Plus, Computers and Applied Sciences Complete, Health Source-Consumer Edition, Health Source: Nursing/Academic Edition, MEDLINE, Web of Science and SPORTDiscuss from inception up until August 2017. Eligibility criteria Randomized controlled trials of high-intensity exercise interventions in cancer survivors (all cancer types) with health-related outcome measures. The guidelines adopted for this review were the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). The search returned 447 articles, of which nine articles (n = 531 participants mean, age 58 ± 9.5 years) met the eligibility criteria. Exercise interventions of between 4 and 18 weeks consisting of high-intensity interval bouts of up to 4-min were compared with a continuous moderate intensity (CMIT) intervention or a control group. High-intensity exercise interventions elicited significant improvements in VO High-intensity exercise interventions improved physical and physiological health-related outcome measures such as cardiovascular fitness and strength in cancer survivors. Given that high-intensity exercise sessions require a shorter time commitment, it may be a useful modality to improve health outcomes in those who are time poor. The risk of adverse events associated with high-intensity exercise was low.
Publisher: Termedia Sp. z.o.o.
Date: 2011
Publisher: Springer Science and Business Media LLC
Date: 10-2003
DOI: 10.1007/S00464-002-9274-Z
Abstract: The vasoactive peptide octreotide has an established role in controlling variceal hemorrhage. The mechanism of action is believed to be a reduction in splanchnic blood flow. A decrease in splanchnic blood flow should be mirrored by a decrease in gastric mucosal blood flow (GMBF). Laser Doppler flowmetry (LDF) should detect changes in GMBF. In seven normal volunteers and four patients with portal hypertension, 100 micro g of octreotide was administered as an intravenous bolus. Continuous LDF measurements were then made at a single point on the midantrum for at least 10 min and plotted against time for each subject. After a variable period of stabilization, GMBF decreased in all subjects except one. This was statistically significant in both the controls and the patients with portal hypertension. Octreotide decreases GMBF in normal and portal hypertensive stomachs. Laser Doppler is a useful and minimally invasive tool to assess the effect of drugs on GMBF.
Publisher: SAGE Publications
Date: 20-09-2012
Abstract: This paper traces the development of children’s multiplatform commissioning at the Australian Broadcasting Corporation (ABC) in the context of the digitalisation of Australian television. Whilst recent scholarship has focussed on ‘post-broadcast’ or ‘second-shift’ industrial practices, designed to engage view(s)ers with proprietary media brands, less attention has been focussed on children’s and young adults’ television in a public service context. Further, although multiplatform projects in the United States and Britain have been the subject of considerable analysis, less work has attempted to contextualise cultural production in smaller media markets. The paper explores two recent multiplatform projects through textual analysis, empirical research (consisting of interviews with key industry personnel) and an investigation of recent policy documents. The authors argue that the ABC’s mixed diet of children’s programming, featuring an educative or social developmental agenda, is complemented by its appeals to audience ‘participation’, with the Corporation maintaining public service values alongside the need to expand audience reach and the legitimacy of its brand. It finds that the ABC’s historical platform infrastructure, across radio, television and online, have allowed it to move beyond a market failure model to exploit multiplatform synergies competitively in the distribution of Australian children’s content to audiences on-demand.
Publisher: Springer Science and Business Media LLC
Date: 15-07-2016
Publisher: OMICS Publishing Group
Date: 2016
Publisher: Informa UK Limited
Date: 20-10-2015
Publisher: South African Medical Association NPC
Date: 02-2018
Publisher: MDPI
Date: 29-01-2021
Publisher: Informa UK Limited
Date: 04-2012
Publisher: Georg Thieme Verlag KG
Date: 07-2006
Abstract: Atopic-related factors, humoral and mucosal immunoglobulins (Ig), and cortisol were measured in 17 professional cyclists competing in the 2003 Vuelta a España (a three-week multi-stage race). Venous blood and saliva s les were obtained the morning before the start of the race (T0), on the first rest day after 10 days of racing (T1), and before the start of the last stage after 21 days of racing (T2). Atopic-related factors, IgE, eosinophil cationic protein (ECP), and eosinophils, were significantly altered during the race. Serum IgE (T1: + 10 %) and ECP (salivary, T1: 113 % and serum, T2: 155 %) were significantly increased, while eosinophils (T1: - 32 %, T2: - 55 %) were significantly lower, than pre-race levels. Salivary sIgA secretion rate was significantly decreased at T2 (- 36 %). Pearson product-moment correlations revealed a modest correlation between salivary sIgA and salivary ECP (T1: r = 0.30 T2: r = 0.48 p < 0.01). Serum IgM, total IgG, IgG1, IgG2, IgA levels, at T1 and T2, and cortisol at T2, were significantly lower than pre-race levels. In conclusion, the elevation in IgE and ECP suggests an up-regulation of atopic-related factors in professional cyclists participating in the Vuelta a España. The correlation between salivary sIgA and salivary ECP indicates a role for sIgA in mediating mucosal inflammation. The alterations in Ig levels may indicate Ig isotype switching. An increasing state of hormonal fatigue may have influenced the observed immune alterations.
Publisher: BMJ
Date: 10-2020
DOI: 10.1136/BMJOPEN-2020-040753
Abstract: To summarise the evidence from interventions investigating the effects of out of care setting activities on people with dementia living in residential aged care. A systematic review. A systematic search of electronic databases (PubMed, PsycINFO, Scopus, Web of Science and the Cochrane Library) was performed to identify intervention trials published from journal inception to January 2020. Controlled trials, or quasi-experimental trials, which measured pre-intervention, post-intervention or during-intervention outcomes, where the participants were required to leave the care setting to participate in an intervention, were eligible for inclusion. Quality appraisal of the studies was performed following the Cochrane Collaboration’s Risk of Bias or Newcastle-Ottawa Scale tools. Of the 4155 articles screened, 11 articles met the inclusion criteria from 9 different studies. The number of participants in the studies ranged from 6 to 70 people living with dementia and lasted for 3 weeks up to 5 months. The interventions were aquatic exercise, wheelchair cycling, art gallery discussion groups, an intergenerational mentorship programme, horse riding, walking and outdoor gardening. Overall, the studies indicated preliminary evidence of psychological (n=7), physical (n=4) and physiological (n=1) benefits, and all interventions were feasible to conduct away from the aged care facilities. However, the low number of participants in the included studies (n=177), the absence of a control group in all but three studies, and potential for selection bias, limits the generalisability of the findings. Activities outside of the residential aged care setting have the potential to be effective at providing a range of benefits for people living with dementia. Higher quality studies are required to encourage care providers to implement these type of activities in dementia care settings. CRD42020166518.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 05-2011
Publisher: Academy of Science of South Africa
Date: 20-12-2004
DOI: 10.17159/2078-516X/2004/V16I2A182
Abstract: Objective. To determine the effect of prolonged endurance exercise on the serum concentrations of eosinophil cationic protein (ECP), immunoglobulin E (IgE) and upper respiratory tract symptoms (URTS). Design. In 11 healthy, experienced volunteers (6 males, 5 females, age 43 ± 9.8 years) the serum concentrations of ECP and IgE were measured, 24 hours prior to projected finishing time, immediately post exercise (IPE), and 3 h, 24 h, and 72 h after an ultramarathon (90 km). Self-reported URTS were also recorded for 14 days after the race. ECP was measured using radioimmunoassay and IgE using the Alastat Microplate Total IgE kit. The after-exercise values were corrected for plasma volume changes, which were calculated from haematocrit and haemoglobin values. Serum concentrations of ECP and IgE were analysed using an analysis of variance (ANOVA) comparing values with before-exercise levels. Level of significance was set at p ≤ 0.05. Results. ECP was significantly elevated at 72 hours (+52%), whilst IgE was not significantly altered after the ultramarathon. There were no reported URTS for the 14 days after the race. Conclusion. The eosinophil is a pro-inflammatory leukocyte involved in bronchial hyperreactivity and allergic inflammation of the airways. IgE is associated with allergic diseases such as asthma and rhinitis. Serum ECP is a sensitive marker of eosinophil activation. The result provides evidence for the non-allergic activation of blood eosinophils during prolonged endurance exercise. Whether this indicates exercise or environmentally induced airway inflammation, or a role for ECP in muscle /tissue repair, are hypotheses that require additional research. SA Sports Medicine Vol.16(2) 2004: 12-16
Publisher: Palacky University Olomouc
Date: 06-10-2017
DOI: 10.5507/AG.2017.014
Publisher: SAGE Publications
Date: 10-2013
DOI: 10.2466/29.22.PMS.117X24Z8
Abstract: Few studies have investigated the effects of music on trained athletes during high intensity endurance tasks. Therefore, this study investigated the effects of different music tempi on performance, psychological, and physiological responses of well-trained cyclists to time trial cycling. 10 male road cyclists ( M age = 35 yr., SD = 7), with a minimum of three years racing experience, performed four 20-km time trials on a Computrainer™ Pro 3D indoor cycle trainer over a period of four weeks. The time-trials were spaced one week apart. The music conditions for each trial were randomised between fast-tempo (140 bpm), medium-tempo (120 bpm), slow-tempo (100 bpm), and no music. Performance (completion time, power output, average speed and cadence), physiological (heart rate, oxygen consumption, breathing frequency and respiratory exchange ratio), psychophysical (RPE), and psychological (mood states) data were collected for each trial. Results indicated no significant changes in performance, physiological, or psychophysical variables. Total mood disturbance and tension increased significantly in the fast-tempo trial when compared with medium and no-music conditions.
Publisher: OMICS Publishing Group
Date: 2018
Publisher: Elsevier BV
Date: 03-2021
Publisher: Springer Science and Business Media LLC
Date: 15-01-2020
DOI: 10.1186/S40798-019-0232-X
Abstract: Performance analysis in rugby union has become an integral part of the coaching process. Although performance analysis research in rugby and data collection has progressed, the utility of the insights is not well understood. The primary objective of this review is to consider the current state of performance analysis research in professional rugby union and consider the utility of common methods of analysing performance and the applicability of these methods within professional coaching practice. SPORTDiscus electronic database was searched for relevant articles published between 1 January 1997 and 7 March 2019. Professional, male 15-a-side rugby union studies that included relevant data on tactical and performance evaluation, and statistical compilation of time-motion analysis were included. Studies were categorised based on the main focus and each study was reviewed by assessing a number of factors such as context, opposition analysis, competition and s le size. Forty-one studies met the inclusion criteria. The majority of these studies measured performance through the collection and analysis of performance indicators. The majority did not provide context relating to multiple confounding factors such as field location, match location and opposition information. Twenty-nine performance indicators differentiated between successful match outcomes however, only eight were commonly shared across some studies. Five studies considered rugby union as a dynamical system however, these studies were limited in analysing lower or national-level competitions. The review highlighted the issues associated with assessing isolated measures of performance, lacking contextual information such as the opposition, match location, period within match and field location. A small number of studies have assessed rugby union performance through a dynamical systems lens, identifying successful characteristics in collective behaviour patterns in attacking phases. Performance analysis in international rugby union can be advanced by adopting these approaches in addition to methods currently adopted in other team sports.
Publisher: Academy of Science of South Africa
Date: 20-12-2004
DOI: 10.17159/2078-516X/2004/V16I2A183
Abstract: Objectives. The human body initiates an acute phase response (APR) in response to a wide range of homeostatic disturbances. This complex series of reactions serves to activate repair processes and prevent ongoing tissue damage. An important aspect of the APR is the de novo synthesis of acute phase proteins (APP), many of which have not been thoroughly investigated. Main outcome measures. Alterations in CRP (C-reactive protein), C1est, C3, C4, C6, rheumatoid factor (RF) and Factor B were determined before and after an ultramarathon. Data were analysed using a one-way analysis of variance comparing values to pre-exercise levels. Significance was set at p 0.05. Design. Venepunctures were performed on athletes participating in an ultramarathon (90 km) 24 hours before, immediately post-exercise (IPE), and 3h, 24h and 72h after the race. Serum was stored at –80°C until analysed. CRP levels in serum were assessed using the N Latex CRP kit. The levels of circulating immune complexes (CIC) were determined using particle-enhanced nephelometry. Complement proteins C1est, C3, C4 and RF were measured using laser nephelometry. C6 and Factor B were determined by radial immunodiffusion. Results. CRP was significantly elevated IPE (58%), 3h post (77%), 24h post (87%) and 72h post (69%). Pre-race CRP levels were above the normative range (5.10 ± 3.08 mg/l), C6 was significantly elevated (p 0.05) at 24h post (7.8%) and 72h post (8.8%) exercise. Factor B was significantly elevated (p 0.05) at 72h post exercise (12.8%). RF was significantly elevated at 72h post exercise (6.7%). Conclusion. Significant increases in selected acutephase reactants occur several days after the exercise event. In addition, as indicated by elevated resting levels of CRP, the athletes began the race with some degree of inflammation, presumably as a result of the cumulative training and racing mileage in preparation for the ultramarathon. SA Sports Medicine Vol.16(2) 2004: 17-21
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 05-2015
Publisher: Oxford University Press (OUP)
Date: 09-06-2021
DOI: 10.1093/AJH/HPAB088
Abstract: Hypertension is a major contributor to cardiovascular diseases and premature death, therefore determining factors that contribute to such a high burden of disease is critically important. This study examined anthropometric and physical measurements, as well as blood and saliva biomarkers, as predictors for hypertension using datasets from the 2008 Health and Retirement Study. A total of 2,924 participants (aged 74.84 ± 6.45 years) were included. Binary logistic regression was performed to ascertain the effects of sex, age, telomere length, C-reactive protein (CRP), body mass index (BMI), and additional markers on the odds of developing hypertension. Males had 2.3 times the odds (odds ratio (OR) = 2.313, confidence interval (CI) 95% (1.391, 3.845) P = 0.001) of being hypertensive if they were obese, females had 1.7 times the odds (OR = 1.788, CI 95% (1.260, 2.536) P = 0.001) if overweight, and 2.4 times (OR = 2.479, CI 95% (1.693, 3.630) P & 0.001) if obese. Age in females was an independent predictor where every 1-year increase in age was tied to a 5.1% increase in being hypertensive (OR = 1.051, CI 95% (1.027, 1.075) P & .001), and CRP (& mg/l) had 1.4 times the odds (OR = 1.447, CI 95% (1.079, 1.942) P = 0.014). This study provides verification for BMI as a predictor for hypertension and proposes age and CRP as predictors for females. Specific sex differences and life stage should be considered when evaluating hypertension risk to improve clinical outcomes and promote healthy aging.
Publisher: S. Karger AG
Date: 2019
DOI: 10.1159/000500040
Abstract: Assistive technology including virtual reality and augmented reality has gained interest as a novel intervention in a range of clinical settings. This technology has the potential to provide mental stimulation, a connection to autobiographical memory through reminiscence, and enhanced quality of life (QoL) to people living with dementia (PLWD) and mild cognitive impairment (MCI). In this mini-review, we examine the available evidence from studies reporting on the potential benefits of virtual and augmented reality to provide enjoyable, leisurely activities that may promote QoL and psychological well-being and facilitate social interaction. In total, 10 studies of varying study designs and durations (5 min to 6 months) using virtual ( i n /i = 9) and augmented reality ( i n /i = 1) were examined in PLWD ( i n /i = 6) and MCI ( i n /i = 3), in addition to 1 study that included participants with both conditions. Overall, the virtual experiences were enjoyed by the participants, improved their mood and apathy, and were preferred when compared with nonvirtual experiences. However, small s le sizes and variations in study design limit the generalizability of the results. Nevertheless, the use of virtual and augmented reality technology for PLWD and MCI is a novel and emerging method which may provide cognitive stimulation and improve well-being. Future research should explore the potential application of this technology to promote social interaction in both the community and aged care settings. We suggest future studies in PLWD and MCI assess the effects of more sustained use of virtual and augmented reality technology on psychological outcomes including QoL, apathy, and depressive symptoms, with the incorporation of physiological biomarker outcomes.
Publisher: S. Karger AG
Date: 2018
DOI: 10.1159/000492457
Abstract: b i Objectives: /i /b This study aimed to investigate the impact of 3 isocaloric exercise programs on cardiac autonomic nervous system (ANS) functioning in children. b i Methods: /i /b One hundred nine children (39% boys and 61% girls) aged 10–13 years (mean 11.07 ± 0.81) were conveniently assigned to 1 of 4 groups as follows: Moderate-intensity continuous training (MICT i n /i = 29) at 65–70% of the predicted maximum heart rate (MHR), High-intensity interval training (HIIT i n /i = 29) at & #x3e 80% of the predicted MHR, HIIT and MICT combined on alternate weeks (ALT i n /i = 27), and a control group ( i n /i = 24). Morning ANS activity was assessed via analysis of heart rate variability (HRV), with the patient in supine position for 10 min, before and after the exercise intervention. b i Data Analysis: /i /b A 2-way analysis of variance was used to evaluate the effects of training on all HRV parameters ( i /i & #x3c 0.05/4 = 0.0125). b i Results: /i /b After 5 weeks of training, significant improvements were observed for ln of the standard deviation of normal-to-normal intervals ( i /i & #x3c 0.0001), ln of the root mean square of successive difference ( i /i & #x3c 0.0001), and ln of standard deviation 1 ( i /i & #x3c 0.0001), with superior results reported in the HIIT group (effect size [ES] = 2.22, 2.69, and 2.69) compared with the MICT (ES = 1.67, 1.75, and 1.75) and ALT (ES = 0.87, 1.06, and 1.06) groups, respectively. b i Conclusion: /i /b Short-term HIIT seems to induce superior alterations in cardiac ANS activity compared to MICT and ALT in children through enhanced vagal activity.
Publisher: Wiley
Date: 10-01-2019
DOI: 10.1002/PTR.6277
Abstract: l-Theanine (l-THE) is a nonproteinogenic amino acid derived from green tea (Camellia sinensis), which exhibits strong antioxidant-like properties and contributes to the favourable umami taste sensation. Several studies have reported that the consumption of this amino acid has many therapeutic effects, including improvements in brain and gastrointestinal function, cancer drug therapeutic efficacies, antihypertensive effects, and improved immune function. Considering the recent Western commercialisation and popularity of green tea consumption as a nootropic agent in humans, the aims of this review were to consolidate the existing knowledge from ex vivo and in vitro animal models and attempt to highlight the applicability of l-THE towards the human clinical trials. Considering the anti-inflammatory and antioxidants effects of l-THE presented in the current review, further research must translate the existing knowledge gained from animal and cell models to exploring the potential metabolic health benefits and moderating effects on the pathogenesis of conditions such as obesity, arthritis, depression, and type 2 diabetes in human trials. This will bridge the gap in literature and provide more insights into the mechanisms driving pathologies characterised by the inflammatory response and oxidative stress.
Publisher: MDPI AG
Date: 14-09-2019
DOI: 10.3390/JFMK4030066
Abstract: Purpose: This study investigated (1) the effect of a progressive resistance training (PRT) program and whey protein intake on maximal muscle strength in human immunodeficiency virus (HIV)-infected in iduals receiving antiretroviral therapy (ART) and (2) alterations in maximal strength 12 wks after the cessation of PRT with continued supplementation. Methods: Sixty HIV-infected in iduals were recruited. Whole body PRT was performed twice weekly for 12 wks. Participants received, in a double-blind placebo controlled manner, either 20 g whey or placebo (maltodextrin) before and immediately after each session. Both PRT groups continued to take either whey protein or placebo for a further 12 wks following the exercise intervention to examine the effects of detraining. Results: Forty participants (mean and standard deviation (SD) age 40.8 (±7.7) years, weight 70.8 (±16) kg, body mass index (BMI) 30.9 (±7.2) kg m2) whey protein /PRT (n = 13), placebo/PRT (n = 17), and a control group (n = 10) completed the study. A significant main effect for time occurred for the bench press (p = 0.02), the squat (p 0.0001), the deadlift (p = 0.001) and the shoulder press (p = 0.02) one-repetition maximum (1RM) in the intervention groups. Conclusion: The PRT program increased maximal strength regardless of whey protein intake. The detraining period demonstrated minimal strength loss, which is beneficial to this population.
Publisher: Elsevier BV
Date: 06-2022
Publisher: Georg Thieme Verlag KG
Date: 10-2019
DOI: 10.1055/A-0991-0268
Abstract: The potential anti-fatigue and performance benefits of hydrogen rich water (HRW) have resulted in increased research interest over the past 5 years. The aim of this study was to assess physiological and perceptual responses to an incremental exercise protocol after administration of 600 ml HRW within 30 min before exercise. This randomized, double blinded placebo-controlled cross over study included twelve healthy males aged 27.1±4.9 years. The exercise protocol consisted of a 10 min warm-up at 1.0 W.kg−1, followed by 8 min at 2.0, 3.0, and 4.0 W.kg−1, respectively. Cardio-respiratory variables, lactate and ratings of perceived exertion (RPE) were assessed in the last minute of each step. A significantly lower blood lactate was found with HRW (4.0±1.6 and 8.9±2.2 mmol.l−1) compared to Placebo (5.1±1.9 and 10.6±3.0 mmol.l−1) at 3.0, and 4.0 W.kg−1, respectively. Ventilatory equivalent for oxygen and RPE exhibited significantly lower values with HRW (32.3±7.2, and 17.8±1.2 points, respectively) compared to Placebo (35.0±8.4, and 18.5±0.8 points, respectively) at 4 W.kg−1. To conclude, acute pre-exercise supplementation with HRW reduced blood lactate at higher exercise intensities, improved exercise-induced perception of effort, and ventilatory efficiency.
Publisher: Canadian Science Publishing
Date: 2021
Abstract: Heart rate variability (HRV) measurement provides non-invasive assessment of autonomic stability and cardiometabolic disease risk. Insufficient physical activity in early childhood may contribute to negative cardiometabolic health. The Active Early Learning (AEL) study was a 6-month randomised controlled trial investigating the effects of a physical activity-based program incorporating movement within the daily curriculum of preschool children. The current study assessed the effects of the AEL intervention on HRV as a measure of cardiac vagal control. Children aged between 3–5 years and enrolled in a preschool with an attendance of ≥15 children were eligible. Physical activity was recorded using an Actigraph wGT3x accelerometer worn at the waist of participants over 3 consecutive days. A Polar H10 chest strap measured HRV with the HF-band and RMSSD representing cardiac vagal control. After 6 months of the AEL trial, linear mixed model analyses revealed a significant intervention effect for increased HF (p = 0.044). The control group did not demonstrate changes in cardiac vagal control after the intervention ceased. Independent of age, sex, physical activity and BMI, the AEL study elicited significant improvements in the cardiac vagal control of participants who received the intervention. Findings highlight the importance of investigating HRV for assessing the cardiometabolic health in young children. ANZCTR trial registration number: ACTRN12619000638134. Novelty: The AEL curriculum improved child HRV independent of age, sex, physical activity and BMI. Heart rate and RR intervals did not demonstrate changes for the intervention and control groups. Multivariate programs for developing physical competence, confidence, knowledge and motivation may improve child health.
Publisher: BMJ
Date: 02-2006
Publisher: Xia & He Publishing
Date: 08-01-2020
Publisher: MDPI AG
Date: 11-11-2016
Publisher: Palacky University Olomouc
Date: 31-12-2017
DOI: 10.5507/AG.2017.021
Publisher: Wiley
Date: 31-10-2019
DOI: 10.1111/AJCO.13263
Publisher: MDPI AG
Date: 10-01-2020
Abstract: Heart rate variability (HRV) is an accepted method for determining autonomic nervous system activity and cardiovascular risk in various populations. This study assessed the validity and reliability of a commercially available finger photoplethysmography (PPG) system for measuring pediatric HRV in a real-world setting. Sixteen healthy children (4.06 ± 0.58 years) were recruited. The PPG system was compared to the Polar H10 heart rate (HR) sensor validated against ECG (gold standard) for HRV measurement. Seated short-term resting R-R intervals were recorded simultaneously using both systems. Recordings were performed on 3 days at the participants’ school. Paired t-tests, effect sizes and Bland–Altman analyses determined the validity of the PPG system. The relative and absolute reliability of both systems were calculated. No HRV parameters were valid for the PPG system. Polar H10 yielded moderate (0.50–0.75) to good (0.75–0.90) relative reliability with R-R intervals and the standard deviation of instantaneous and continuous R-R variability ratio showing the best results (ICCs = 0.84). Polar H10 displayed better absolute reliability with the root mean square of successive differences, R-R intervals and HR showing the lowest values (TEM% 12%). The use of the Polar H10 and not the PPG system is encouraged for HRV measurement of young children in an educational real-world setting.
Publisher: Public Library of Science (PLoS)
Date: 14-02-2018
Publisher: Human Kinetics
Date: 11-2023
Abstract: Endurance exercise can disturb intestinal epithelial integrity, leading to increased systemic indicators of cell injury, hyperpermeability, and pathogenic translocation. However, the interaction between exercise, diet, and gastrointestinal disturbance still warrants exploration. This study examined whether a 6-day dietary intervention influenced perturbations to intestinal epithelial disruption in response to a 25-km race walk. Twenty-eight male race walkers adhered to a high carbohydrate (CHO)/energy diet (65% CHO, energy availability = 40 kcal·kg FFM −1 ·day −1 ) for 6 days prior to a Baseline 25-km race walk. Athletes were then split into three subgroups: high CHO/energy diet ( n = 10) low-CHO, high-fat diet (LCHF: n = 8 g/day CHO, energy availability = 40 kcal·kg FFM −1 ·day −1 ) and low energy availability ( n = 10 65% CHO, energy availability = 15 kcal·kg FFM −1 ·day −1 ) for a further 6-day dietary intervention period prior to a second 25-km race walk (Adaptation). During both trials, venous blood was collected pre-, post-, and 1 hr postexercise and analyzed for markers of intestinal epithelial disruption. Intestinal fatty acid-binding protein concentration was significantly higher (twofold increase) in response to exercise during Adaptation compared to Baseline in the LCHF group ( p = .001). Similar findings were observed for soluble CD14 ( p .001) and lipopolysaccharide-binding protein ( p = .003), where postexercise concentrations were higher (53% and 36%, respectively) during Adaptation than Baseline in LCHF. No differences in high CHO/energy diet or low energy availability were apparent for any blood markers assessed ( p .05). A short-term LCHF diet increased intestinal epithelial cell injury in response to a 25-km race walk. No effect of low energy availability on gastrointestinal injury or symptoms was observed.
Publisher: Human Kinetics
Date: 08-2014
Abstract: The relationship between physical activity levels, salivary cortisol, and the metabolic syndrome (MetSyn) score was examined. Twenty-three girls (8.4 ± 0.9 years) had a fasting blood draw, waist circumference and blood pressure measured, and wore an ActiGraph accelerometer for 5 days. Saliva s les were collected to measure cortisol levels. Previously established cut points estimated the minutes spent in moderate, vigorous, and moderate-to-vigorous physical activity. A continuous MetSyn score was created from blood pressure, waist circumference, high-density-lipoprotein (HDL), triglyceride, and glucose values. Correlation analyses examined associations between physical activity, cortisol, the MetSyn score, and its related components. Regression analysis examined the relationship between cortisol, the MetSyn score, and its related components adjusting for physical activity, percent body fat, and sexual maturity. Vigorous physical activity was positively related with 30 min post waking cortisol values. The MetSyn score was not related with cortisol values after controlling for confounders. In contrast, HDL was negatively related with 30 min post waking cortisol. Triglyceride was positively related with 30 min post waking cortisol and area under the curve. The MetSyn score and many of its components were not related to cortisol salivary levels even after adjusting for physical activity, body fat percentage, and sexual maturity.
Publisher: Informa UK Limited
Date: 11-07-2017
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 04-02-2021
DOI: 10.1519/JSC.0000000000003979
Abstract: Botek, M, Krejčí, J, McKune, A, Valenta, M, and Sládečková, B. Hydrogen rich water consumption positively affects muscle performance, lactate response, and alleviates delayed onset of muscle soreness after resistance training. J Strength Cond Res 36(10): 2792–2799, 2022—Positive outcomes of hydrogen rich water (HRW) supplementation on endurance performance have been shown, but the effects of HRW in resistance training are unclear. The aim of this study was to assess the effects of 1,260 ml of HRW intake on physiological, perceptual, and performance responses to a resistance training and after 24 hours of recovery. This randomized, double-blinded placebo-controlled cross-over study included 12 men aged 23.8 ± 1.9 years. Subjects performed a half squat, knee flexion, and extension exercises with the load set at 70% of 1 repetition maximum for 3 sets (10 reps/set). Lunges were performed with a load of 30% of body mass for 3 sets (20 reps/set). Time of each set, lactate, and ratings of perceived exertion were assessed mid-way through exercise and immediately after the exercise. Creatine kinase, muscle soreness visual analog scale ratings, countermovement jump, and heart rate variability were evaluated before the training and at 30 minutes, 6, and 24 hours of recovery. Lunges were performed faster with HRW compared with placebo ( p 0.001). Hydrogen rich water reduced lactate at mid-way and immediately after the exercise (HRW: 5.3 ± 2.1 and 5.1 ± 2.2, placebo: 6.5 ± 1.8 and 6.3 ± 2.2 mmol·L −1 , p ≤ 0.008). Visual analog scale ratings were significantly lower with HRW (26 ± 11 vs. 41 ± 20 mm, p = 0.002) after 24 hours of recovery. In conclusion, an acute intermittent HRW hydration improved muscle function, reduced the lactate response, and alleviated delayed onset of muscle soreness.
Publisher: Informa UK Limited
Date: 29-03-2019
DOI: 10.1080/21551197.2019.1590287
Abstract: The potential for B-vitamins to reduce plasma homocysteine (Hcy) and reduce the risk of Alzheimer's disease (AD) has been described previously. However, the role of Apolipoprotein E є4 (APOE4) in this relationship has not been adequately addressed. This case-control study explored APOE4 genotype in an Australian s le of 63 healthy in iduals (female = 38 age = 76.9 ± 4.7 y) and 63 in iduals with AD (female = 35, age = 77.1 ± 5.3 y). Findings revealed 55 of 126 participants expressed the APOE4 genotype with 37 of 126 having both AD and the APOE4 genotype. Analysis revealed an increased likelihood of AD when Hcy levels are >11.0 µmol/L (p = 0.012), cysteine levels were <255 µmol/L (p = 0.033) and serum folate was <22.0 nmol/L (p = 0.003 in males only). In females, dietary intake of total folate <336 µg/day (p=0.001), natural folate <270 µg/day (p = 0.011), and vitamin B2 < 1.12 mg/day (p = 0.028) was associated with an increased AD risk. These results support Hcy, Cys, and SF as useful biomarkers for AD, irrespective of APOE4 genotype and as such should be considered as part of screening and managing risk of AD.
Publisher: MDPI AG
Date: 30-07-2016
Abstract: This study examined whether cardiorespiratory fitness (CRF) and body composition are associated with salivary secretory immunoglobulin A (SIgA), a mucosal immunity marker, and salivary alpha-amylase (sAA), a marker of stress-related sympathetic nervous system (SNS) activity, in South African children. Morning (7:30-8:00 a.m.) saliva s les were collected from 132 children (10.05 ± 1.68 years old, 74 females, 58 males). Body composition, resting blood pressure, and predicted maximal aerobic capacity (VO2max) were determined, and SIgA and sAA were quantified. Obese children had significantly higher sAA compared with overweight and normal weight children (p < 0.01). SIgA secretion rate was significantly lower in obese and overweight vs. normal weight children (p < 0.01). Multiple-linear regression analysis revealed that body mass index (BMI) (p < 0.05) and diastolic blood pressure (DBP) (p < 0.05) were independent predictors of sAA with CRF acting as a mitigator. Age and BMI predicted SIgA secretion rate (p < 0.05) with BMI (p < 0.001) found to be an independent predictor of SIgA secretion rate. Obesity, based on BMI, was associated with elevated SNS activity and lowered mucosal immunity. CRF-mitigated sympathetic activation was not associated with mucosal immunity.
Publisher: Springer Science and Business Media LLC
Date: 16-08-2022
DOI: 10.1007/S13197-022-05570-6
Abstract: The non-proteinous amino acid L-theanine (L-THE) is associated with a range of health benefits including improvements in immune function, cardiovascular outcomes and cognition. The aims of this study were to develop a food product (mango sorbet ms-L-THE) containing physiologically relevant doses of L-THE (0.2/100 g w/w) and determine its antioxidant, physicochemical and sensory properties in comparison to a mango sorbet without L-THE (ms). Total phenolic and flavanol content, and antioxidant analysis (DPPH, FRAP and ABTS) were determined spectrophotometrically. Both products were also evaluated for acceptability and likeability in healthy participants using the 9-point hedonic scale. Any differences that could be caused by the addition of L-THE were examined using the triangle test. Results indicated no significant differences between ms-L-THE and ms in taste of the products (p 0.05), and the ms-L-THE was well received and accepted as a potential commercial product. Findings of the DPPH assay indicated significant difference between the two products (p 0.05). In conclusion, we have successfully created a mango sorbet that contains a potentially physiologically relevant concentration of L-THE with antioxidant properties that could be used as a novel method of L-THE delivery to clinical and healthy populations.
Publisher: Oxford University Press (OUP)
Date: 11-2019
DOI: 10.1093/GERONI/IGZ038.204
Abstract: Art gallery programs tailored to the needs of people living with dementia are becoming more popular worldwide. This study aimed to observe the effects of six consecutive weekly discussion-based small group visits to the National Gallery of Australia Art and Dementia program on the salivary cortisol (SC) diurnal rhythm, salivary interleukin-6, quality of life (QoL), depressive symptoms, and cognitive function. Twenty-five participants (17 female mean age 84.6 ± 7.27 years) completed the study with data collection at baseline, post-intervention, and at a six-week follow-up. Statistical methods were selected based on data distribution. The waking to evening (WE) SC ratio was altered (p = 0.016) (Baseline: 1.35 (1.19, 1.64), Post-intervention: 1.72 (1.54, 1.96), Follow-up: 1.44 (1.22, 1.79)) in the 22 participants who provided viable saliva s les. The WE SC ratio was higher post-intervention compared with baseline (p = 0.011), indicating a more dynamic SC rhythm, but returned to baseline levels at follow-up (p = 0.020). Interleukin-6 levels were unchanged (p = 0.664). In the total s le, no improvements in QoL (Proxy) (p = 0.165) were observed. However, self-reported depressive symptoms differed (p = 0.006), decreasing post-intervention (2.00 (1.00, 2.00)) compared with baseline (3.00 (2.00, 4.50)) (p = 0.015), and verbal fluency was affected (p = 0.027), improving from baseline (2.00 (0.00, 3.00)) to post-intervention (2.00 (0.50, 4.00)) (p = 0.027). Art and Dementia programs appear to have quantifiable benefits, including improved hypothalamic-pituitary-adrenal axis function, justifying a longer controlled trial inclusive of physiological outcomes.
Publisher: Clinics Cardive Publishing
Date: 10-10-2011
Publisher: Academy of Science of South Africa
Date: 20-12-2003
DOI: 10.17159/2078-516X/2003/V15I3A226
Abstract: SA Sports Medicine Vol.15(3) 2003: 29-31
Publisher: BMJ
Date: 20-02-2020
DOI: 10.1136/BJSPORTS-2019-101293
Abstract: Using an expert consensus-based approach, a rugby union Video Analysis Consensus (RUVAC) group was formed to develop a framework for video analysis research in rugby union. The aim of the framework is to improve the consistency of video analysis work in rugby union and help enhance the overall quality of future research in the sport. To reach consensus, a systematic review and Delphi method study design was used. After a systematic search of the literature, 17 articles were used to develop the final framework that described and defined key actions and events in rugby union (rugby). Thereafter, a group of researchers and practitioners with experience and expertise in rugby video analysis formed the RUVAC group. Each member of the group examined the framework of descriptors and definitions and rated their level of agreement on a 5-point agreement Likert scale (1: strongly disagree 2: disagree 3: neither agree or disagree 4: agree 5 : strongly agree ). The mean rating of agreement on the five-point scale (1: strongly disagree 5: strongly agree ) was 4.6 (4.3–4.9), 4.6 (4.4–4.9), 4.7 (4.5–4.9), 4.8 (4.6–5.0) and 4.8 (4.6–5.0) for the tackle, ruck, scrum, line-out and maul, respectively. The RUVAC group recommends using this consensus as the starting framework when conducting rugby video analysis research. Which variables to use (if not all) depends on the objectives of the study. Furthermore, the intention of this consensus is to help integrate video data with other data (eg, injury surveillance).
Publisher: MDPI AG
Date: 10-02-2022
Abstract: Molecular hydrogen (H2) is potentially a novel therapeutic gas for acute post-coronavirus disease 2019 (COVID-19) patients because it has antioxidative, anti-inflammatory, anti-apoptosis, and antifatigue properties. The aim of this study was to determine the effect of 14 days of H2 inhalation on the respiratory and physical fitness status of acute post-COVID-19 patients. This randomized, single-blind, placebo-controlled study included 26 males (44 ± 17 years) and 24 females (38 ± 12 years), who performed a 6-min walking test (6 MWT) and pulmonary function test, specifically forced vital capacity (FVC) and expiratory volume in the first second (FEV1). Symptomatic participants were recruited between 21 and 33 days after a positive polymerase chain reaction test. The experiment consisted of H2 lacebo inhalation, 2 × 60 min/day for 14 days. Results showed that H2 therapy, compared with placebo, significantly increased 6 MWT distance by 64 ± 39 m, FVC by 0.19 ± 0.24 L, and, in FEV1, by 0.11 ± 0.28 L (all p ≤ 0.025). In conclusion, H2 inhalation had beneficial health effects in terms of improved physical and respiratory function in acute post-COVID-19 patients. Therefore, H2 inhalation may represent a safe, effective approach for accelerating early function restoration in post-COVID-19 patients.
Publisher: Medpharm Publications
Date: 13-11-2014
Abstract: Armed service recruits are faced with many stressors, including a strenuous training regimen that may have an impact on their physiological functioning. The Cardio Stress Index (CSI) is a noninvasive marker of the stress that the heart is experiencing. The aim of the study was to test the physiological impact of 20 weeks of intense training of armed service recruits, using CSI as a noninvasive biomarker of cardiac stress. Armed service recruits are faced with many stressors, including a strenuous training regimen that may have an impact on their physiological functioning. The CSI is a noninvasive marker of the stress that the heart is experiencing. The calculation of the CSI is based on the duration of vascular excitation (QRS duration), heart rate, heart rhythm and standard deviation of the duration of time between each successive cardiac cycle (RR-interval). The aim of the present study was to test the physiological impact of 20 weeks of strenuous training of armed service recruits, using CSI as a noninvasive biomarker of cardiac stress. Experiments were conducted at three points in time (weeks 1, 12, 20) during the basic military training of armed service recruits (n = 202, males = 115, females = 87), aged between 18 and 24 years. Variables measured include: Resting CSI, heart rate and blood pressure. Data analysis was performed, using paired t-tests for pairwise comparisons of week 1 (baseline) with week 12 week 12 with week 20 and week 1 with week 20. The average CSI and heart rate remained within normal values for male participants on all three testing occasions. However, baseline readings for females were significantly higher during week 1. There was an overall decrease in the CSI in the 20 week time frame. From this study it seems as if the CSI measurement is a noninvasive method to establish the effects of training on the health of the heart.
Publisher: Wiley
Date: 05-2014
DOI: 10.1111/WRR.12168
Abstract: Recent studies, using modalities other than laser Doppler, have indicated that perfusion during negative-pressure wound therapy (NPWT) is reduced, contrary to world literature. The aim of the present study was to evaluate whether the measuring technique of the laser Doppler could be influenced by the compressive nature of NPWT dressings and whether this could explain the conflicting findings. A hypothesis that it may be possible for laser Doppler to record similar readings to those obtained during NPWT by merely compressing tissues manually was tested on 12 NPWT dressings, with each undergoing an alternating series of manual compressive forces and NPWT (-125 mmHg). During the periods of NPWT (n = 12), the mean perfusion recording increased in five experiments, reduced in six, and remained unchanged in one. During the period when manual pressure was applied (n = 12), there was a mean increase in perfusion in six experiments and a reduction in six. The type of change in perfusion (increase or decrease) was the same for both NPWT and manual pressure in 10 of the 12 experiments. In conclusion, laser Doppler can incorrectly record increased perfusion when tissues are compressed, implying that it is flawed in the field of NPWT research as tissues are always compressed to some degree by the NPWT dressing.
Publisher: Academy of Science of South Africa
Date: 20-12-2003
DOI: 10.17159/2078-516X/2003/V15I3A223
Abstract: SA Sports Medicine Vol.15(3) 2003: 17-21
Publisher: Elsevier BV
Date: 11-2018
Publisher: African Journal for Physical Activity and Health Sciences, Tshwane University of Technology
Date: 09-2021
Publisher: Elsevier BV
Date: 10-2020
Publisher: Elsevier BV
Date: 11-2019
Publisher: Public Library of Science (PLoS)
Date: 08-10-2018
Publisher: Elsevier BV
Date: 10-2019
Publisher: MDPI AG
Date: 23-03-2020
DOI: 10.3390/FOODS9030371
Abstract: Consumption of L-Theanine (L-THE) has been associated with a sensation of relaxation, as well as a reduction of stress. However, these physiological responses have yet to be elucidated in humans where L-THE is compared alongside food or as a functional ingredient within the food matrix. The aim of this study was to determine the physiological responses of a single intake of a potential functional food product (mango sorbet) containing L-THE (ms-L-THE 200 mgw/w) in comparison to a flavour and colour-matched placebo (ms). Eighteen healthy male participants were recruited in this randomised, double-blind, placebo-controlled trial. The participants were required to consume ms-L-THE or placebo and their blood pressure (BP) (systolic and diastolic), heart rate (HR), and heart rate variability (HRV) were monitored continuously over 90 minutes. Eleven males (age 27.7 ± 10.8 years) completed the study. Changes in area under the curve for systolic and diastolic blood pressure and HRV over the 90 minute observation period indicated no differences between the three conditions (all p 0.05) or within in idual groups (all p 0.05). The values for heart rate were also not different in the placebo group (p = 0.996) and treatment group (p = 0.066), while there was a difference seen at the baseline (p = 0.003). Based on the findings of this study, L-THE incorporated in a food matrix (mango sorbet) demonstrated no reduction in BP or HR and showed no significant parasympathetic interaction as determined by HRV high-frequency band and low-frequency/high-frequency ratio. Further studies should be focussed towards the comparison of pure L-THE and incorporation within the food matrix to warrant recommendations of L-THE alongside food consumption.
Publisher: Elsevier BV
Date: 02-2021
Publisher: Clinics Cardive Publishing
Date: 29-10-2012
Publisher: MDPI AG
Date: 30-09-2021
Abstract: Whole- (WBC) and partial-body cryotherapy (PBC) are commonly used sports medicine modalities for the treatment of injury and exercise recovery. Physiological and perceptual effects have the potential to be utilised in a novel application that involves pre-exercise WBC and PBC exposure to improve physical performance. A systematic literature search of multiple databases was conducted in July 2021 to identify and evaluate the effects of pre-exercise exposure of WBC or PBC on physical performance measures, and any potential translational effects. The following inclusion criteria were applied: (1) use of WBC or PBC exposure pre-exercise, (2) use of WBC or PBC in healthy and/or athletic populations, (3) control group was used in the data collection, and (4) investigated physiological, psychosocial or direct physical performance impacts of pre-exercise cryotherapy exposure. A total of 759 titles were identified, with twelve relevant studies satisfying the inclusion criteria after full-text screening. The twelve studies were categorised into three key areas: performance testing (n = 6), oxidative stress response (n = 4) and lysosomal enzyme activity (n = 2). The potential for eliciting favourable physical and physiological responses from pre-exercise WBC or PBC is currently unclear with a paucity of good quality research available. Furthermore, a lack of standardisation of cryotherapy protocols is a current challenge.
Publisher: Elsevier BV
Date: 04-2020
DOI: 10.1016/J.PHYSBEH.2020.112806
Abstract: An unhealthy lifestyle negatively alters autonomic nervous system (ANS) activity as reflected by decreased heart rate variability (HRV), increasing cardiovascular disease (CVD) risk. Research investigating the effect of modifiable lifestyle factors on ANS activity in young children is limited. Early identification of these risk factors is vital to improving long-term in idual and public health outcomes. A systematic review was conducted to assess the effect of maternal or child modifiable lifestyle factors on child ANS activity. Following the 2009 PRISMA guidelines, three electronic databases were searched from February 2018 - July 2019 for articles describing human trials between 1996 - 2019. Included studies examined ANS activity of children between 28 weeks gestational age - 6 years in relation to modifiable lifestyle CVD risk factors. Twenty-six studies fulfilled inclusion criteria. Sixteen studies reported that modifiable lifestyle factors significantly influenced the HRV of children. Increased HRV was significantly associated with higher maternal zinc and omega-3 fatty acid intake, regular maternal aerobic exercise and a non-smoking environment. Child diet and body composition demonstrated some support for an association between these modifiable lifestyle factors and child HRV. There is cross-sectional evidence supporting an association between maternal lifestyle factors and child HRV. Evidence is less supportive of a relationship between child modifiable lifestyle factors and child HRV. Monitoring the effects of lifestyle interventions on the ANS via HRV measurements of both mother and child may identify child CVD risk.
Publisher: Human Kinetics
Date: 05-2022
Abstract: Introduction : Athletes engaged in repeated-sprint training in the heat can be at an increased risk of gastrointestinal ischemia and damage in response to a redistribution of blood to working skeletal muscles and the skin. This study investigated the effects of repeated sprinting in hot and cool conditions on markers of gastrointestinal damage. Methods : Twenty-five, well-trained, nonheat acclimated male team-sport athletes completed a five-session, repeated-sprint training regimen over 7 days in either HOT (40 °C and 40% relative humidity [RH]) or COOL (20 °C and 40% RH) conditions. Participants underwent a 20-min warm-up and four sets of 5 × 6-s maximal cycling sprints, with 24-s rest and 5-min recovery between sets. Venous blood was collected pre-, post-, and 1 hr postexercise and analyzed for intestinal fatty acid binding protein, lipopolysaccharide binding protein, soluble CD14, and heat-shock protein. Results : Intestinal fatty acid binding protein concentrations were significantly increased ( p .004) postexercise (593 and 454 pg/ml) and 1 hr postexercise (466 and 410 pg/ml) on both Days 1 and 5 in HOT. Soluble CD14 increased by 398 and 308 ng/ml postexercise ( p = .041), and lipopolysaccharide binding protein increased by 1,694 ng/ml postexercise on Day 1 in HOT ( p .05) and by 1,520 ng/ml on Day 5 in COOL ( p = .026). Core and skin temperature, rating of perceived exertion, and thermal sensation were higher ( p .05) in HOT on Days 1 and 5 during sprinting. Conclusions : Repeated sprinting in the heat induced greater thermal strain and mild changes in gastrointestinal damage, likely attributable to the combination of environmental conditions and maximal-intensity exercise.
Publisher: Elsevier BV
Date: 12-2021
Publisher: MDPI AG
Date: 25-01-2022
DOI: 10.3390/NU14030508
Abstract: Hydrogen-rich water (HRW) supplementation has been shown to have an antifatigue effect across different modes of exercise. However, its effect on repeated sprint performance is unknown. The aim of this study was to assess the effect of pre-exercise HRW consumption on repeated sprint performance, lactate, and perceptual responses using a repeated sprint protocol. This randomized, double blinded, placebo controlled, crossover study included 16 professional, male soccer players aged 18.8 ± 1.2 years. Athletes performed two indoor tests, particularly 15 × 30 m track sprints interspersed by 20 s of recovery, separated by a 1-week washout period. Sprint time was measured at 15 m and 30 m. Ratings of perceived exertion were assessed immediately after each sprint, and post-exercise blood lactate concentration was measured after the last sprint. There were significantly faster sprint times after HRW consumption compared with placebo at 15 m for the 14th and 15th sprints, representing improvements in time of 3.4% and 2.7%, respectively. Sprint time at 30 m also significantly improved by 1.9% in the HRW group in the last sprint. However, neither lactate concentrations nor ratings of perceived exertion were significantly different between HRW and placebo. Pre-exercise HRW supplementation is associated with an increased ability to reduce fatigue, especially during the later stages of repeated sprint exercise.
Publisher: Elsevier BV
Date: 07-1998
DOI: 10.1016/S1078-5884(98)80092-0
Abstract: To determine the predictive power of laser Doppler fluxmetry (LDF), both heated and unheated, as a preoperative investigation of wound healing potential in dysvascular patients requiring utation, by comparison with transcutaneous oxygen pressure measurement (TcpO2) and the limb to chest TcpO2 index. Thirty-five non-diabetic patients with peripheral vascular disease were investigated before utation. Heated and unheated LDF and heated TcpO2 measurements were taken on the chest wall and at the routine above-knee, below-knee and mid-foot utation levels. Wound healing potential was evaluated against a TcpO2 index value of 0.55 and on clinical outcome. A heated LDF value of 4.9 arbitrary units (au) was shown by receiver-operator characteristic curve to have the best predictive power, with an overall accuracy for preoperative prediction of wound healing of 91.4%, and a predictive value for wound failure of 89%. Based on the heated LDF of 4.9 au, review of 26 utations performed shows the overall accuracy for preoperative prediction of wound healing of 92.3%, a predictive value for wound healing of 100%, and a predictive value for wound failure of 62.5%. A heated LDF value of 4.9 au appears to be a useful predictor of the potential of an utation site to heal.
Publisher: MDPI AG
Date: 28-04-2020
Abstract: Consumption of anthocyanins (ACNs), due to their antioxidant, anti-inflammatory and anti-apoptotic effects, has been proposed for the prevention and treatment of several different diseases and conditions. ACNs are recognized as one of the leading nutraceuticals for prolonging health benefits through the attenuation of oxidative stress, and inflammatory or age-related diseases. Increased consumption of ACNs has the potential to attenuate the damage ensuing from oxidative stress, inflammation, enhance cardiometabolic health, and delay symptoms in predisposed neuropathology. A myriad of evidence supports ACN consumption as complementary or standalone treatment strategies for non-communicable diseases (NCDs) including obesity, diabetes, cardiovascular disease (CVD), neurodegenerative diseases, as well as, more recently, for the modulation of gut bacteria and bone metabolism. While these findings indicate the beneficial effects of ACN consumption, their food sources differ vastly in ACN composition and thus potentially in their physiological effects. Consumption of foods high in ACNs can be recommended for their potential beneficial health effects due to their relatively easy and accessible addition to the everyday diet.
Publisher: MDPI AG
Date: 13-02-2020
DOI: 10.3390/BS10020059
Abstract: Post-traumatic stress disorder (PTSD) is a prevalent and debilitating condition associated with psychological conditions and chronic diseases that may be underpinned by dysfunction in the autonomic nervous system (ANS), the hypothalamic-pituitary-adrenal (HPA) axis and chronic systemic low-grade inflammation. The objective of this pilot study was to determine psychological, ANS [heart rate variability (HRV)], HPA (salivary cortisol) and inflammatory (salivary C-Reactive Protein) responses to a bout of vigorous exercise in male first responders, military veterans and active duty personnel with (n = 4) and without (n = 4) PTSD. Participants (50.1 ± 14.8 years) performed a thirteen-minute, vigorous intensity (70%–80% of heart rate max), one-on-one boxing session with a certified coach. Physiological and psychological parameters were measured before, during, immediately after to 30 min post-exercise, and then at 24 h and 48 h post. The effect sizes demonstrated large to very large reductions in HRV that lasted up to 48 h post-exercise in the PTSD group compared with unclear effects in the trauma-exposed control (TEC) group. There were unclear effects for depression, anxiety and stress as well as salivary biomarkers for both groups at all time-points. Findings may reflect stress-induced changes to the ANS for PTSD sufferers.
Publisher: Human Kinetics
Date: 03-2022
Abstract: Purpose : To determine whether a single acute preexercise bout of partial-body cryotherapy (PBC) enhanced maximal-effort shuttle run performance, salivary enzyme concentration, and self-reported performance readiness. Methods : A total of 18 male rugby league players (age = 20.1 [0.5] y mass = 91.4 [12.4] kg) were exposed to either PBC for 3 minutes at −136°C (1°C) or a control condition prior to a continuous, high-intensity 6 × 40-m shuttle run test. Passive saliva s les were collected to determine salivary alpha amylase (sAA) concentration. Perceived performance readiness and well-being questionnaires were completed using a 1-to-7 Likert scale. Results : The PBC exposure did not elicit a greater improvement in 6 × 40-m shuttle run performance in comparison with the control condition (standardized difference +0.4 [5.9%] P = .881 mean ± 90% confidence limits). The increase in sAA concentration was moderately greater 15 minutes after PBC compared with the control group (+67 [32%], P = .012) and remained moderately higher up to 2 hours post-PBC exposure compared with the control condition (+41 [40%], P = .045). There were greater improvements in self-reported perceptions of muscle soreness (+0.6 [0.4%], P = .043 units ±90% confidence limits) and mood (+0.6 [0.7%], P = .038) after PBC compared with control. Conclusions : It appears that a single 3-minute bout of PBC does not augment maximal effort shuttle run performance in elite rugby league players. Beneficial increases in sAA concentration, coupled with improved perceptions of muscle soreness and mood, should be explored further for alternative training or precompetition practices.
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 05-2014
Publisher: Elsevier BV
Date: 04-2022
DOI: 10.1016/J.NUT.2021.111555
Abstract: Prickly Pear (PP) fruit is proposed to have anti-atherosclerotic and anti-hyperglycemic effects. The aim of this study was to examine the effects of a single consumption of PP juice on modifiable blood and physiological markers of cardiovascular disease risk in healthy men using a postprandial hyperlipidemia model. This was a double-blind, randomized, placebo-controlled, crossover trial with 17 healthy men (body mass index 22.6 ± 2.04 kg/m Key findings included a lower HRV measure after PP consumption (main effect for group, P ≤0.001-0.020) but no differences for TC, TG, LDL-C, or HDL-C. Consumption of PP (with high-fat muffin), did not alter traditional cardiovascular disease risk responses but rather markers of HRV, beyond an expected increase in glucose attributed to the carbohydrate content of the trials foods. Additionally, macronutrient content is important when understanding HRV responses to meals.
Publisher: Human Kinetics
Date: 06-2022
Abstract: Purpose : This study evaluated the effect of partial-body cryotherapy (PBC) exposure 1, 2, or 3 hours before maximal-effort jump performance, salivary enzyme concentration, perceived readiness, and well-being. Methods : Male team-sport players (N = 27 24.2 [3.6] y 91.5 [13.2] kg) were exposed to a blinded bout of PBC (−135°C [6°C]) and control (−59°C [17°C]) either 1, 2, or 3 hours prior to countermovement jumps. Passive saliva s les were collected to determine α-amylase concentration. Self-reported performance readiness and well-being questionnaires were completed using a 1–5 Likert scale. Results : Differences in the change in mean countermovement jump velocity and absolute power between PBC and control were unclear at 1 hour (+1.9% [5.3%], P = .149 +0.7% [10.6%], P = .919 mean difference [90% confidence limits]), 2 hours (+3.3% [2.7%], P = .196 +7.8% [7.4%], P = .169), and 3 hours postexposure (+3.1% [3.3%], P = .467 +0.7% [4.8%], P = .327). Salivary α-amylase concentration was elevated 15 minutes postexposure in the 1-hour (+61% [14%], P = .008) and 2-hour groups (+55% [12%], P = .013). The increase in self-reported performance readiness was higher after PBC (+2.4 [1.2] units, P = .046) in the 2-hour group and by 1.4 (1.1) units ( P = .023) after 3 hours. Mental fatigue was favorably decreased 2 hours after PBC exposure (+0.5 [0.1], P = .041). Conclusions : An acute exposure of PBC elicits potentially favorable but unclear changes in countermovement jump performance. The PBC enhances salivary α-amylase concentration and perceived performance readiness, reduces mental fatigue, and could be useful in sport-specific training or competitions.
Publisher: Human Kinetics
Date: 09-2023
Abstract: National- and international-level rugby sevens athletes are exposed to high training and competition loads over the course of a competitive season. Research on load monitoring and body-system responses is widespread however, the primary focus has been on optimizing performance rather than investigating or improving cardiovascular health. There is a degree of cardiovascular remodeling, as well as local and systemic inflammation, in response to excessive exercise. These responses are moderated by many factors including previous exercise exposure, current exercise intensity and duration, age, race, and gender, as well as sport-specific physiology. For these reasons, high-performing female rugby sevens athletes may have a unique cardiovascular risk profile different from males and other rugby codes. This review aimed to characterize the training and competition loads, as well as the anthropometric and physiological profiles, of female rugby sevens athletes discuss the potential impacts these may have on the cardiovascular system and provide recommendations on future research regarding the relationship between rugby sevens training and competition loads and cardiovascular health. Movement demands, competition formatting, and training routines could all contribute to adverse cardiovascular adaptations. Anthropometric data and physiological characteristics may also increase the risk of cardiovascular disease. Future research needs to adopt measures of cardiovascular health to obtain a greater understanding of cardiovascular profiles and risk factors in female rugby sevens athletes.
Publisher: SAGE Publications
Date: 15-03-2022
DOI: 10.1177/17479541221087384
Abstract: Experiential knowledge of elite international coaches was investigated to reveal insights on successful rugby union strategies and tactics required to prevail in international competition. Three elite coaches who coached at a Rugby World Cup were interviewed using an in-depth, semi-structured approach. They were asked about specific strategies and tactics which they believed were required to be successful in an upcoming international tournament and a thematic analysis of qualitative data followed. Particular interest was paid to the influence of potential constraints and how these factors impact performance behaviours over time. The importance of an effective tactical kicking game in attacking strategies was highlighted, along with an adaptable defensive structure following a turnover. Unsuccessful performance behaviours in international rugby were reported to be connected with an irrational kicking game, a weak defensive line and losing possession off set-piece plays. These results support the need for a multidisciplinary approach, where exploring coaches’ knowledge presents an opportunity to enhance understanding across the performance analysis field. Further research is needed to complement experiential knowledge with quantitative research in rugby performance analysis.
Publisher: Mary Ann Liebert Inc
Date: 09-2016
Abstract: Obesity and metabolic syndrome are significant global health issues, with current public health messages predominately focused on altering dietary and physical activity behaviors. Resveratrol is a polyphenol (stilbenoid) commonly found in grapes, and human trials to date have shown conflicting and limited beneficial effects with respect to health. The aim of this study was to determine the effect of resveratrol supplementation on reducing body weight and modifying associated inflammatory markers. A systematic review was undertaken following the PRISMA guidelines and using five indexed databases (OVID MEDLINE, Cochrane Library, Web of Science, SCOPUS, and CINAHL). A search strategy was formulated to select randomized, double-blind, placebo-controlled human trials investigating the effects of resveratrol supplementation on obesity or overweight, including body weight, metabolic and inflammatory markers. Five thousand five hundred sixty-nine studies published from 1990 to November 2015 were identified, with only nine papers meeting the inclusion criteria. The studies involved 208 participants (aged 49.2 ± 8.3 years) and utilized a substantial range of resveratrol doses (75-3000 mg/day). Study durations were a minimum of 2 weeks (14-90 days). Seven studies indicated no significant change in body mass index or body weight (P > 0.05), and three studies showed no improvements in fat mass, fat volume, or abdominal fat distribution (P > 0.05). Four studies included measurements of inflammatory markers, with three of these finding resveratrol supplementation to have a significant positive effect (P > 0.05). Based on the included studies, there is currently insufficient evidence to support the recommendation of resveratrol supplements in management of obesity. However, there were significant but not entirely consistent anti-inflammatory effects after resveratrol supplementation in overweight and obese in iduals.
Publisher: Human Kinetics
Date: 2023
Abstract: Purpose : This study aimed to determine the effects of a field-based priming session on perceptual, physiological, and performance responses in female rugby sevens athletes. Methods : Thirteen highly trained female rugby sevens players (age: 20.7 [2.0] y height: 169.3 [4.8] cm weight: 68.8 [7.9] kg) completed either a 20-minute field-based priming session or a control condition. Perceptual, physiological, and performance variables were collected at baseline (PRE) and 5 (POST5), 30 (POST30), and 120 minutes (POST120) postintervention. Data were analyzed using Bayesian mixed effects models. Results : The priming protocol had a larger increase in mental readiness (maximum a posteriori [MAP] = 20, 95% high-density intervals [HDI] = −4 to 42, probability of direction [PD]% = 95, % in region of practical equivalence [ROPE] = 9.7), physical readiness (MAP = 20.1, 95% HDI = −4.6 to 42.1, PD% = 93, % in ROPE = 10.6), and testosterone (MAP = 14.9, 95% HDI = 0.5 to 27.7, PD% = 98, % in ROPE = 5.6) than the control POST30. Cognitive performance decreased POST120 in the priming condition for congruent (MAP = 0.02, 95% HDI = −0.06 to 0.00, PD% = 95, % in ROPE = 6.4) and incongruent tasks (MAP = 0.00, 95% HDI = −0.07 to 0.00, PD% = 98, % in ROPE = 3.2) when compared with the control. Conclusions : Perceptual and physiological markers improved POST30 in the priming condition. Findings indicate that perceptual and physiological responses to priming were not coupled with performance improvements. Priming was not accompanied by perceptual, physiological, or performance improvements at POST120.
Publisher: BMJ
Date: 09-2005
Publisher: Index Copernicus
Date: 2012
Publisher: Canadian Science Publishing
Date: 12-2019
Abstract: The primary purpose of this study was to assess the reliability of 3 methods estimating energy expenditure (EE) during and in response to resistance exercise. Ten males (aged 29.4 ± 10.2 years) with ≥2 months resistance training (RT) experience performed 3 training sessions incorporating the bench press and back-squat sessions were separated by 48 to 72 h. Total energy expenditure (TEE) was estimated using a Suunto T6D Heart Rate Monitor and 2 methods (named “Scott” and “Magosso”) that used oxygen uptake and blood lactate measurements to determine aerobic and anaerobic energy expenditure (AnEE). For TEE, relative reliability for both the Scott and Magosso methods remained “nearly perfect” across all testing days for the bench press and back-squat with interclass correlations (ICC) 0.93 and percentage of the typical error measurement (TEM%) below 5.8%. The heart rate method showed moderate variability between testing days for both exercises ICCs ranged between 0.66–0.92 with TEM% between 18%–37% during the bench press and 11%–17% during the back-squat. The estimation of AnEE showed that the Scott and Magosso methods had “strong” to “very strong” relative reliability for both exercises however, a low absolute reliability was observed. Mean EE was significantly higher in the Scott and Magosso methods during the bench press kJ and back-squat kJ, with the heart rate method estimating 358 kJ and 416 kJ. The Scott and Magosso methods showed a high degree of reliability between testing days when measuring EE. Heart rate methods may significantly underestimate EE during and in response to RT.
Publisher: Informa UK Limited
Date: 04-04-2022
Publisher: Human Kinetics
Date: 2019
Abstract: Objective : To examine the effect of a physical treatment (speed, power, and strength [SPS] training) and psychosocial treatment (group motivational presentation) on salivary testosterone (sal-T), salivary cortisol (sal-C), and sal-T-to-sal-C ratio (T:C) in professional rugby. Methods : Fourteen male rugby players (age = 25.9 [2.5] y, height = 186.1 [6.7] cm, and body mass = 104.1 [12.7] kg) participated in this study. Testing occurred across 2 d on 2 separate occasions (week 1 and week 2). On day 1 of both weeks, participants completed an SPS training session. On day 2 of both weeks, participants undertook a field-based rugby training session. In week 2, participants underwent an additional treatment in the form of a motivational presentation given by a respected former player before the rugby session. Saliva was collected before and after SPS training and before and after the rugby session and was assayed for testosterone and cortisol. Results : No differences were found between weeks for sal-T at any time point, but sal-C was higher in week 2 before and after SPS and before rugby on day 2 ( P .05). In both weeks, T:C increased following SPS ( P .02, ES 0.91 [0.13, 1.69]). T:C increased when the motivational presentation accompanied rugby training ( P = .07, ES = 1.06 [0.27, 1.85]). Sal-C, not sal-T, drove changes in T:C ( P .001). Conclusions : Physical or psychosocial treatments may affect sal-T, sal-C, and T:C, and in idual variation in responses to treatments may exist.
Publisher: Cambridge University Press (CUP)
Date: 09-01-2018
DOI: 10.1017/S0007114517003452
Abstract: Nutraceuticals have generated interest as a way to mitigate the cognitive decline in older adults. The aim of this systematic review was to determine the evidence for these claims from the scientific literature in randomised, double-blinded, controlled trials (duration: ≥1 year participants: n ≥100 age(mean): ≥65 years). Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched four electronic databases (PubMed, Scopus, CINAHL and Web of Science) and identified twenty-five studies published between the 15·June·2006 and 14·June·2016. Interventions included B-vitamins, n -3 fatty acids, antioxidant vitamins and herbs. Of the B-vitamin studies, four found benefits to cognition with supplementation. The first of these B-vitamin studies, in in iduals with mild cognitive impairment ( n 266 duration=2 years), included benefit to executive function ( P =0·015) and improvements in the Mini-Mental State Examination (MMSE) among participants with baseline homocysteine above 11·3 µmol/l ( P ·001). In the same s le, the second study found cognitive benefits of B-vitamins dependent on the higher baseline plasma n -3 fatty acid status. The third B-vitamin study ( n 900 duration=2 years) reported improved performance in immediate ( P =0·046) and delayed recall ( P =0·013), whereas the fourth study ( n 856 duration=2 years) reported slower rate of cognitive decline in the MMSE ( P =0·05). One study investigating DHA treatment ( n 402 duration=1·5 years) revealed the slower rate of cognitive change in apoE e4 non-carriers ( P =0·03). As only five included studies revealed notable benefits, presently based on the specific compounds explored here, there is not compelling evidence to support the use nutraceuticals to improve cognition in the elderly. Future long-term trials of nutraceuticals should investigate interactions with lifestyle, blood biomarkers and genetic risk factors.
Publisher: Termedia Sp. z.o.o.
Date: 26-04-2022
Abstract: The objective of this cross-sectional study was to evaluate the hydration status of Czech First League soccer players, and to compare the reported fluid intake, perceived fluid intake and thirst sensation of euhydrated (EU) and dehydrated (DE) players. The study involved 124 Czech male professional soccer players (age 25.2±5.0 years) participating in annual winter, pre-season laboratory testing. Hydration status was assessed based on urine specific gravity (USG), euhydration was set at USG≤1.020. Fluid intake and thirst perception were evaluated by a questionnaire. The s le mean for USG was 1.021±0.008, 56% of players were dehydrated. Reported daily fluid intake was significantly (p .001, d=0.95, large effect) higher in EU compared to DE players. Daily fluid intake negatively correlated with USG (rS=-0.46, p .001, medium effect). The fluid intake perception score was significantly (p=0.005, d=0.54, medium effect) better in EU compared to DE players. Reported intake perception scores negatively correlated with USG (rS=-0.32, p .001, medium effect). However, there was no correlation (rS=-0.09, p=0.34, trivial effect) between thirst perception scores and USG. Thirst perception scores were not significantly different between EU and DE players (p=0.35, d=0.18, trivial effect). Our results indicated that self-assessment of both daily fluid intake and perceived fluid intake matched with objective hydration status, while self-assessment of thirst perception was not an appropriate indicator of hydration status in elite soccer players.
Publisher: Palacky University Olomouc
Date: 30-06-2016
DOI: 10.5507/AG.2016.008
Publisher: Elsevier BV
Date: 06-2017
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 11-2017
DOI: 10.1519/JSC.0000000000002067
Abstract: Strahorn, J, Serpell, BG, McKune, A, and Pumpa, KL. Effect of physical and psychosocial interventions on hormone and performance outcomes in professional rugby union players: a systematic review. J Strength Cond Res 31(11): 3158–3169, 2017—This systematic review investigates the acute effects of physical or psychosocial interventions on testosterone and cortisol responses in elite male rugby union players, and the subsequent association with physical performance areas (e.g., strength, power, sprint performance) or key performance indicators (e.g., coach-identified skills). Medline (via EBSCO), SPORTDiscus, Web of Science, InformIT, ProQuest, Cochrane, and Scopus were searched for relevant articles. Nine articles met the inclusion criteria, with 6 articles examining the effect of speed, strength or power training, and the remaining 3 psychosocial interventions. Quality assessment of the articles as determined by their PEDro score was either 6 or 7 out of 11. This review found that both physical and psychosocial interventions can alter testosterone and cortisol, and physical performance areas important for rugby union are affected by these changes. The limited literature in the field supports the notion that physical interventions of short duration and high intensity, and psychosocial interventions that create a positive environment may elicit a hormonal response that is associated with favorable performance outcomes. Studies that reported psychosocial interventions suggest that testosterone and cortisol may be altered in elite rugby players without metabolic stress, something of great interest to elite athletes and coaches who are looking to elicit a performance advantage without increasing athlete load. Overall, this review identified that when the testosterone responses to an intervention are notably greater than that of cortisol, favorable outcomes are likely. Further research is required to improve our understanding on how to best manipulate training to induce these favorable changes.
Publisher: Human Kinetics
Date: 07-2021
Abstract: Along with digestion and absorption of nutrients, the gastrointestinal epithelium acts as a primary intestinal defense layer, preventing luminal pathogens from entering the circulation. During exercise in the heat, epithelial integrity can become compromised, allowing bacteria and bacterial endotoxins to translocate into circulation, triggering a systemic inflammatory response and exacerbating gastrointestinal damage. While this relationship seems clear in the general population in endurance/ultraendurance exercise, the aim of this systematic review was to evaluate the effect of exercise in the heat on blood markers of gastrointestinal epithelial disturbance in well-trained in iduals. Following the 2009 Preferred Reporting Items for Systematic Reviewed and Meta-Analyses guidelines, five electronic databases were searched for appropriate research, and 1,885 studies were identified. Five studies met the inclusion criteria and were subject to full methodological appraisal by two reviewers. Critical appraisal of the studies was conducted using the McMasters Critical Review Form. The studies investigated changes in markers of gastrointestinal damage (intestinal fatty acid–binding protein, endotoxin, and/or lipopolysaccharide-binding protein) following acute exercise in warm to hot conditions (≥ 30 °C) and included trained or well-trained participants with direct comparisons to a control temperate condition (≤ 22 °C). The studies found that prolonged submaximal and strenuous exercise in hot environmental conditions can acutely increase epithelial disturbance compared with exercise in cooler conditions, with disturbances not being clinically relevant. However, trained and well-trained populations appear to tolerate exercise-induced gastrointestinal disturbance in the heat. Whether this is an acquired tolerance related to regular training remains to be investigated.
Publisher: African Journals Online (AJOL)
Date: 29-06-2004
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 07-2012
Start Date: 2010
End Date: 06-2013
Amount: $252,365.00
Funder: Australian Research Council
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