ORCID Profile
0000-0002-3759-3423
Current Organisation
University of South Australia
Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the Feedback Form.
Publisher: Springer Science and Business Media LLC
Date: 21-09-2018
Publisher: IEEE
Date: 09-2015
Publisher: JMIR Publications Inc.
Date: 10-06-2021
DOI: 10.2196/29770
Abstract: The postnatal period can be a challenging time for women, with mothers experiencing a range of emotions. As a woman transitions to motherhood, she adjusts to a new sense of self and forms a new relationship with her infant. Becoming a mother is a complex cognitive and social process that is unique for each woman and is influenced and shaped by culture. The emerging mother-infant relationship is a significant factor in maternal well-being and infant development, with the bond between the mother and her baby being critical to the development of secure attachment. It has been recognized that the strength of this relationship is the main predictor of how well a child will do throughout life. There has been a global focus on the importance of the first 1000 days, with Australia identifying this as a national priority. Midwives are ideally placed to support mothers during the development of the mother-infant relationship, providing care through the early postnatal period, which has been identified as a sensitive period for the development of the mother-infant relationship. The aim of this study is to explore how midwives can support the emerging mother-infant relationship in the context of cultural ersity and develop an appropriate co-designed intervention in the early postnatal period. This study will use a mixed method approach, specifically the exploratory sequential design (intervention development variant). This study will be undertaken in 3 phases: 1 qualitative phase, which is followed by 2 quantitative phases. Phase 1 will include a scoping review to explore interventions that have influenced the development of the mother-infant relationship, and then, interviews will be undertaken with women exploring their early experiences of motherhood, followed by 3 co-design workshops. The workshops will engage with multilevel stakeholder representatives where, through partnership and participation, they will propose and develop an intervention to support the emerging mother-infant relationship. Phase 2 will develop and pilot 2 purpose-designed evaluation surveys to evaluate the co-designed intervention from the perspective of both mothers and midwives. Phase 3 will implement and evaluate the co-designed intervention using pre- and postmeasures and feedback from the purpose-designed surveys. Phase 1 has commenced and is expected to be completed by August 2021. Phase 2 is expected to be completed by September 2021, with phase 3 commencing in October 2021. The study will be completed by March 2023. The results of this study will be shared with a variety of audiences and will contribute to the body of knowledge on the mother-infant relationship, potentially improving the understanding of this relationship for women and midwives. This may result in improved strategies for care, with mothers benefiting from enhanced experience and satisfaction during the early postnatal period.
Publisher: Oxford University Press (OUP)
Date: 02-01-2018
Abstract: There are major challenges ahead for clinicians treating patients with atrial fibrillation (AF). The population with AF is expected to expand considerably and yet, apart from anticoagulation, therapies used in AF have not been shown to consistently impact on mortality or reduce adverse cardiovascular events. New approaches to AF management, including the use of novel technologies and structured, integrated care, have the potential to enhance clinical phenotyping or result in better treatment selection and stratified therapy. Here, we report the outcomes of the 6th Consensus Conference of the Atrial Fibrillation Network (AFNET) and the European Heart Rhythm Association (EHRA), held at the European Society of Cardiology Heart House in Sophia Antipolis, France, 17-19 January 2017. Sixty-two global specialists in AF and 13 industry partners met to develop innovative solutions based on new approaches to screening and diagnosis, enhancing integration of AF care, developing clinical pathways for treating complex patients, improving stroke prevention strategies, and better patient selection for heart rate and rhythm control. Ultimately, these approaches can lead to better outcomes for patients with AF.
Publisher: MDPI AG
Date: 11-03-2022
DOI: 10.3390/SU14063289
Abstract: Collaborative robots offer opportunities to increase the sustainability of work and workforces by increasing productivity, quality, and efficiency, whilst removing workers from hazardous, repetitive, and strenuous tasks. They also offer opportunities for increasing accessibility to work, supporting those who may otherwise be disadvantaged through age, ability, gender, or other characteristics. However, to maximise the benefits, employers must overcome negative attitudes toward, and a lack of confidence in, the technology, and must take steps to reduce errors arising from misuse. This study explores how dynamic graphical signage could be employed to address these issues in a manufacturing task. Forty employees from one UK manufacturing company participated in a field experiment to complete a precision pick-and-place task working in conjunction with a collaborative robotic arm. Twenty-one participants completed the task with the support of dynamic graphical signage that provided information about the robot and the activity, while the rest completed the same task with no signage. The presence of the signage improved the completion time of the task as well as reducing negative attitudes towards the robots. Furthermore, participants provided with no signage had worse outcome expectancies as a function of their response time. Our results indicate that the provision of instructional information conveyed through appropriate graphical signage can improve task efficiency and user wellbeing, contributing to greater workforce sustainability. The findings will be of interest for companies introducing collaborative robots as well as those wanting to improve their workforce wellbeing and technology acceptance.
Publisher: MDPI AG
Date: 14-10-2021
DOI: 10.3390/NU13103593
Abstract: Co-design, the method of involving users, stakeholders, and practitioners in the process of design, may assist to improve the translation of health evidence into tangible and acceptable intervention prototypes. The primary objective of this review was to identify and describe co-design techniques used in nutrition research. The secondary objective was to identify associations between co-design techniques and intervention effectiveness. An integrative review was performed using the databases Emcare, MEDLINE, PsycINFO and Google Scholar. Eligible studies included those that: (1) utilised participatory research or co-design techniques, (2) described development and/or evaluation of interventions aimed at improving dietary behaviours or nutrition, and (3) targeted community-dwelling adults aged ≥18 years. We identified 2587 studies in the initial search and included 22 eligible studies. There were 15 studies that utilised co-design techniques, with a strong focus on engagement of multiple stakeholder types and use of participatory research techniques. No study implemented a complete co-design process. Most studies (14/15) reporting outcomes reported positive health (maximum p 0.001) or health behaviour outcomes attributed to the intervention hence, associations between co-design techniques and effectiveness could not be determined. Currently published intervention studies have used participatory research approaches rather than co-design methods. Future research is required to explore the effectiveness of co-design nutrition interventions.
Publisher: IGI Global
Date: 2015
DOI: 10.4018/978-1-4666-8205-4.CH003
Abstract: This chapter furthers discourse between digital data content and the creation of physical artifacts based on an interpretation of the data. Building on original research by the author, the chapter asks the questions: why should we consider translating digital data into a physical form? And what happens to how we understand, read, and relate to digital information when it is presented in this way? The author discusses whether or not the concept of the data-driven object is simply a novel visualization technique or a useful tool to add insight and accessibly to the complex language of digital data sets, for audiences unfamiliar with reading data in more conventional forms. And the author explores the issues connected to the designing of data into the material world, including fabrication techniques such as 3D printing and craft-based making techniques, together with the use of metaphor and visual language to help communicate and contextualize data.
Publisher: Informa UK Limited
Date: 04-05-2023
Publisher: Elsevier BV
Date: 07-2023
Publisher: Springer Science and Business Media LLC
Date: 14-03-2023
DOI: 10.1186/S40359-023-01092-8
Abstract: The mother-infant relationship is complex and dynamic, informing the psychological development of the infant through bonding and attachment. Positive early interactions influence the quality of this relationship. Midwives are well placed to support the developing relationship between the mother and baby, yet there has been limited research exploring the role of the midwife in this context. To explore interventions that have been provided by the midwife which support the development of the maternal-fetal or mother-infant relationship amongst a low-risk population from pregnancy, and up to six weeks postnatal. The review also sought to understand the types of interventions developed, format and delivery, outcomes measured and if cultural considerations had been incorporated. A scoping review of the research literature was undertaken using the Joanna Briggs Institute framework. Five online databases were searched for relevant articles published in English from 2000 to 2021. Sixteen articles met the inclusion criteria. Three themes emerged: (1) viewing the fetus as separate from the mother, (2) focused activities on the maternal-infant relationship and (3) targeted educational interventions. Providing focused activities and targeted education during the pre and postnatal periods support the development of the mother-infant relationship. Significantly, there was insufficient research that considered the influence of culture in supporting the mother-infant relationship. Further research is required to develop interventions that include a erse s le to ensure culturally appropriate activities can be integrated into care during pregnancy and/or the postnatal period provided by midwives.
Publisher: Elsevier BV
Date: 07-2017
Publisher: The Design Society
Date: 2020
Publisher: JMIR Publications Inc.
Date: 19-04-2021
Abstract: he postnatal period can be a challenging time for women, with mothers experiencing a range of emotions. As a woman transitions to motherhood, she adjusts to a new sense of self and forms a new relationship with her infant. Becoming a mother is a complex cognitive and social process that is unique for each woman and is influenced and shaped by culture. The emerging mother-infant relationship is a significant factor in maternal well-being and infant development, with the bond between the mother and her baby being critical to the development of secure attachment. It has been recognized that the strength of this relationship is the main predictor of how well a child will do throughout life. There has been a global focus on the importance of the first 1000 days, with Australia identifying this as a national priority. Midwives are ideally placed to support mothers during the development of the mother-infant relationship, providing care through the early postnatal period, which has been identified as a i sensitive period /i for the development of the mother-infant relationship. he aim of this study is to explore how midwives can support the emerging mother-infant relationship in the context of cultural ersity and develop an appropriate co-designed intervention in the early postnatal period. his study will use a mixed method approach, specifically the exploratory sequential design (intervention development variant). This study will be undertaken in 3 phases: 1 qualitative phase, which is followed by 2 quantitative phases. Phase 1 will include a scoping review to explore interventions that have influenced the development of the mother-infant relationship, and then, interviews will be undertaken with women exploring their early experiences of motherhood, followed by 3 co-design workshops. The workshops will engage with multilevel stakeholder representatives where, through partnership and participation, they will propose and develop an intervention to support the emerging mother-infant relationship. Phase 2 will develop and pilot 2 purpose-designed evaluation surveys to evaluate the co-designed intervention from the perspective of both mothers and midwives. Phase 3 will implement and evaluate the co-designed intervention using pre- and postmeasures and feedback from the purpose-designed surveys. hase 1 has commenced and is expected to be completed by August 2021. Phase 2 is expected to be completed by September 2021, with phase 3 commencing in October 2021. The study will be completed by March 2023. he results of this study will be shared with a variety of audiences and will contribute to the body of knowledge on the mother-infant relationship, potentially improving the understanding of this relationship for women and midwives. This may result in improved strategies for care, with mothers benefiting from enhanced experience and satisfaction during the early postnatal period.
Publisher: Springer Science and Business Media LLC
Date: 11-11-2021
DOI: 10.1186/S12889-021-12102-Y
Abstract: Co-design has the potential to create interventions that lead to sustainable health behaviour change. Evidence suggests application of co-design in various health domains has been growing however, few public-facing digital interventions have been co-designed to specifically address the needs of adults at risk of Type 2 diabetes (T2D). This study aims to: (1) co-design, with key stakeholders, a digital dietary intervention to promote health behaviour change among adults at risk of T2D, and (2) evaluate the co-design process involved in developing the intervention prototype. The co-design study was based on a partnership between nutrition researchers and designers experienced in co-design for health. Potential end-users (patients and health professionals) were recruited from an earlier stage of the study. Three online workshops were conducted to develop and review prototypes of an app for people at risk of T2D. Themes were inductively defined and aligned with persuasive design (PD) principles used to inform ideal app features and characteristics. Participants were predominantly female (range 58–100%), aged 38 to 63 years (median age = 59 years), consisting of a total of 20 end-users and four experts. Participants expressed the need for information from credible sources and to provide effective strategies to overcome social and environmental influences on eating behaviours. Preferred app features included tailoring to the in idual’s unique characteristics, ability to track and monitor dietary behaviour, and tools to facilitate controlled social connectivity. Relevant persuasive design principles included social support , reduction (reducing effort needed to reach target behaviour) , tunnelling (guiding users through a process that leads to target behaviour) , praise , rewards , and self-monitoring . The most preferred prototype was the Choices concept, which focusses on the users’ journey of health behaviour change and recognises progress, successes, and failures in a supportive and encouraging manner. The workshops were rated successful, and feedback was positive. The study’s co-design methods were successful in developing a functionally appealing and relevant digital health promotion intervention. Continuous engagement with stakeholders such as designers and end-users is needed to further develop a working prototype for testing.
Publisher: National Institute for Health and Care Research
Date: 10-2019
DOI: 10.3310/HSDR07360
Abstract: Patients are increasingly being asked to provide feedback about their experience of health-care services. Within the NHS, a significant level of resource is now allocated to the collection of this feedback. However, it is not well understood whether or not, or how, health-care staff are able to use these data to make improvements to future care delivery. To understand and enhance how hospital staff learn from and act on patient experience (PE) feedback in order to co-design, test, refine and evaluate a Patient Experience Toolkit (PET). A predominantly qualitative study with four interlinking work packages. Three NHS trusts in the north of England, focusing on six ward-based clinical teams (two at each trust). A scoping review and qualitative exploratory study were conducted between November 2015 and August 2016. The findings of this work fed into a participatory co-design process with ward staff and patient representatives, which led to the production of the PET. This was primarily based on activities undertaken in three workshops (over the winter of 2016/17). Then, the facilitated use of the PET took place across the six wards over a 12-month period (February 2017 to February 2018). This involved testing and refinement through an action research (AR) methodology. A large, mixed-methods, independent process evaluation was conducted over the same 12-month period. The testing and refinement of the PET during the AR phase, with the mixed-methods evaluation running alongside it, produced noteworthy findings. The idea that current PE data can be effectively triangulated for the purpose of improvement is largely a fallacy. Rather, additional but more relational feedback had to be collected by patient representatives, an unanticipated element of the study, to provide health-care staff with data that they could work with more easily. Multidisciplinary involvement in PE initiatives is difficult to establish unless teams already work in this way. Regardless, there is merit in involving different levels of the nursing hierarchy. Consideration of patient feedback by health-care staff can be an emotive process that may be difficult initially and that needs dedicated time and sensitive management. The six ward teams engaged variably with the AR process over a 12-month period. Some teams implemented far-reaching plans, whereas other teams focused on time-minimising ‘quick wins’. The evaluation found that facilitation of the toolkit was central to its implementation. The most important factors here were the development of relationships between people and the facilitator’s ability to navigate organisational complexity. The settings in which the PET was tested were extremely erse, so the influence of variable context limits hard conclusions about its success. The current manner in which PE feedback is collected and used is generally not fit for the purpose of enabling health-care staff to make meaningful local improvements. The PET was co-designed with health-care staff and patient representatives but it requires skilled facilitation to achieve successful outcomes. The National Institute for Health Research Health Services and Delivery Research programme.
Publisher: Springer US
Date: 2009
Publisher: Informa UK Limited
Date: 04-05-2022
Publisher: Springer US
Date: 2009
Publisher: IEEE
Date: 2005
DOI: 10.1109/IV.2005.43
Publisher: Common Ground Research Networks
Date: 2011
Publisher: IGI Global
Date: 2013
DOI: 10.4018/978-1-4666-2961-5.CH002
Abstract: This chapter discusses a current shift away from thinking about ideas of virtual reality, towards a conversation around hybrid digital hysical constructs and the notions of mixed or augmented reality. In particular the chapter explores how physical artifacts that are based on data extracted from computer generated virtual spaces are being created as a way of challenging how we read, interpret, and respond to digital information. This emerging trend for the realization of data sets into three-dimensional (3D) physical objects is discussed from the perspective of creative practice and digital information visualization. In these new constructs, digital data sets are concretized into a physical form, remediated from information sources, such as mobile phone coverage records, crime statistics, and temperature patterns. Through a series of ex les, the chapter will investigate how these tangible translations can change our relationship to screen-based digital content, in particular statistical data, and seeks to reveal how by encoding digital information into a physical object we can establish a way of reading this data through spatial, temporal, and material variations that sit outside of the computer-monitor and the digital environment. Rapid prototyping making techniques are discussed as a trigger for a conversation around the ontological and epistemological readings of these liminal physical/data objects.
Publisher: Springer International Publishing
Date: 2022
Publisher: ACM Press
Date: 2004
Publisher: IGI Global
Date: 2016
DOI: 10.4018/978-1-4666-9840-6.CH015
Abstract: This chapter furthers discourse between digital data content and the creation of physical artifacts based on an interpretation of the data. Building on original research by the author, the chapter asks the questions: why should we consider translating digital data into a physical form? And what happens to how we understand, read, and relate to digital information when it is presented in this way? The author discusses whether or not the concept of the data-driven object is simply a novel visualization technique or a useful tool to add insight and accessibly to the complex language of digital data sets, for audiences unfamiliar with reading data in more conventional forms. And the author explores the issues connected to the designing of data into the material world, including fabrication techniques such as 3D printing and craft-based making techniques, together with the use of metaphor and visual language to help communicate and contextualize data.
Publisher: Bristol University Press
Date: 05-2022
Publisher: JMIR Publications Inc.
Date: 11-2021
Abstract: nteractive, mixed-reality technologies such as augmented reality (AR), virtual reality (VR) and holographic technology may provide a novel, low-cost solution to fast-track the translation of evidence into practice and may help overcome barriers to both mental health and asthma management service uptake. he aim of this study was to investigate if mixed reality technology is an acceptable mechanism for the delivery of a component of CBT for the management of symptoms of elevated psychological distress among young people with asthma. o explore the perceived acceptability of these technologies, mixed reality tools were evaluated via qualitative, one-on-one interviews with young people with asthma and symptoms of psychological distress, parents/caregivers of young people with asthma and symptoms of psychological distress, and relevant health professionals. The Theoretical Framework of Acceptability (TFA) was used for deductive coding of recorded interview transcripts. hree young people with asthma and symptoms of psychological distress (2 female, mean age (years) = 14, SD= 1.73), four parents/caregivers of in iduals with asthma (1 female, mean age (years) = 55, SD= 14.58) and six health professionals (4 females, mean age = 40.8, SD= 4.32) consented to participate. Four constructs – experienced affective attitude, experienced effectiveness, self-efficacy and intervention coherence – were coded in all participant transcripts. The most frequently coded constructs were experienced affective attitude and intervention coherence both reported a total of 96 times, while the least frequently coded construct was anticipated opportunity cost reported a total of 5 times. Participants were mostly positive about the mixed reality resources. However, some concerns were raised regarding ethicality, particularly in relation to privacy, accessibility, and messaging. Participants noted the need for technology to be used in conjunction with face-to-face engagement with health professionals, and that some patients would respond to this type of delivery mechanism better than others. hese results suggest that mixed reality technology for the purposes of delivery of psychological intervention may be an acceptable addition to current healthcare practices for young people with asthma and symptoms of psychological distress. he study was prospectively registered with the Australia and New Zealand Clinical Trials Registry (ANZCTR): ACTRN12620001109998.
Publisher: SAGE Publications
Date: 2021
DOI: 10.1177/16094069211008333
Abstract: Australia has one of the highest asthma prevalence rates in the world, with this chronic and debilitating condition affecting one in nine people. The health and mental wellbeing of young people with asthma are worse than not only their peers without asthma but also worse than that of people with asthma at other ages. Psychological interventions could be beneficial in treating symptoms of elevated psychological distress in patients with asthma. However, evidence suggests that engagement with mental health services is low in this population. Technology-based solutions that engage youth may overcome barriers to service uptake for both mental health and asthma management. To fast-track the successful translation of evidence-based treatment into practice, interactive, mixed-reality technologies such as augmented reality (AR), virtual reality (VR) and holographic technology may provide a novel, low-cost solution, yet to date, methodological rigor in the evaluation of mixed reality for this purpose is lacking. To evaluate the perceived usability and acceptability of these technologies, mixed reality tools will be developed by the author team to deliver a component of a psychological intervention for treatment of elevated psychological distress among young people with asthma. Qualitative research will be conducted through one-on-one interviews with young people with asthma, parents/caregivers of young people with asthma, and with health professionals, during which participants will have time to interact with the resources. Moderator guides will be used to direct interviews, and will be supplemented with a questionnaire, including Likert-type measures of usability and acceptability to facilitate triangulation of data. Understanding and data obtained through this study will be used to develop version 2.0 mixed reality tools, which will be tested for feasibility in a RCT. Improving access to and uptake of evidence-based treatments for elevated psychological distress in young people with asthma may reduce the burden of this highly prevalent disease.
Publisher: JMIR Publications Inc.
Date: 26-07-2023
DOI: 10.2196/34629
Abstract: Interactive, mixed reality technologies such as augmented reality, virtual reality, and holographic technology may provide a novel solution to fast-track the translation of evidence into practice. They may also help overcome barriers to both mental health and asthma management service uptake, such as cost, availability of appointments, fear of judgment, and quality of care. This study aimed to investigate if mixed reality technology is an acceptable mechanism for the delivery of a component of cognitive and behavioral therapies for the management of elevated psychological distress among young people with asthma. To explore the perceived acceptability of these technologies, mixed reality tools were evaluated via qualitative, 1-on-1 interviews with young people with asthma and symptoms of psychological distress, parents/caregivers of young people with asthma and symptoms of psychological distress, and relevant health professionals. The Theoretical Framework of Acceptability was used for the deductive coding of the recorded interview transcripts. This study enrolled the following participants: (1) 3 adolescents with asthma and symptoms of psychological distress with a mean age of 14 (SD 1.7) years (2) 4 parents/caregivers of adolescents with asthma with a mean age of 55 (SD 14.6) years and (3) 6 health professionals with a mean age of 40.8 (SD 4.3) years. A total of 4 constructs—experienced affective attitude, experienced effectiveness, self-efficacy, and intervention coherence—were coded in all participant transcripts. The most frequently coded constructs were experienced affective attitude and intervention coherence, which were reported a total of 96 times. The least frequently coded construct was anticipated opportunity cost, which was reported a total of 5 times. Participants were mostly positive about the mixed reality resources. However, some concerns were raised regarding ethicality, particularly regarding privacy, accessibility, and messaging. Participants noted the need for technology to be used in conjunction with face-to-face engagement with health professionals and that some patients would respond to this type of delivery mechanism better than others. These results suggest that mixed reality technology to deliver psychological interventions may be an acceptable addition to current health care practices for young people with asthma and symptoms of psychological distress. Australia and New Zealand Clinical Trials Registry ACTRN12620001109998 anzctr.org.au/Trial/Registration/TrialReview.aspx?id=380427
Publisher: Wiley
Date: 05-2023
DOI: 10.1111/JADE.12459
Abstract: Co‐design and other associated design approaches often deploy creative and making approaches in facilitating collaborative practices. In a therapeutic setting, engagement in creative and making activities have been associated with improvements in people's well‐being, yet when deploying these as part of co‐design practices, these outcomes are often overlooked. This paper presents the results from a series of workshops that focused on the well‐being benefits of participating in co‐design practices. The research uses Max‐Neef's (1991). Theory of Needs to explore how innate human needs might be satisfied through participation in co‐design practices, and demonstrates how this framework might be used for planning and evaluating co‐design practices through a wellbeing lens. Finally, it suggests that future generations of design practitioners would benefit from exposure to the consideration of co‐design as a process of “welldoing.”
Publisher: Springer International Publishing
Date: 2018
Publisher: ACM Press
Date: 2006
Publisher: EPSRC UK-RAS Network
Date: 12-10-2018
DOI: 10.31256/UKRAS17.27
Publisher: Ovid Technologies (Wolters Kluwer Health)
Date: 06-2023
DOI: 10.1097/FTD.0000000000001047
Abstract: Different software applications have been developed to support health care professionals in in idualized drug dosing. However, their translation into clinical practice is limited, partly because of poor usability and integration into workflow, which can be attributed to the limited involvement of health care professionals in the development and implementation of drug dosing software. This study applied codesign principles to inform the design of a drug dosing software to address barriers in therapeutic drug monitoring using vancomycin as an ex le. Three workshops (face-to-face and online) were conducted by design researchers with pharmacists and prescribers. User journey storyboards, user personas, and prototyping tools were used to explore existing barriers to practice and opportunities for innovation through drug dosing software design. A prototype of the software interface was developed for further evaluation. Health care professionals (11 hospital pharmacists and 6 prescribers) with ≥2 years of clinical experience were recruited. Confidence and software usability emerged as the main themes. Participants identified a lack of confidence in vancomycin dosing and pharmacokinetic understanding and difficulty in accessing practice guidelines as key barriers that could be addressed through software implementation. Accessibility to information (eg, guidelines and pharmacokinetic resources) and information presentation (eg, graphical) within the dosing software were dependent on the needs and experience of the user. A software prototype with a speedometer-dial visual to convey optimal doses was well received by participants. The perspectives of health care professionals highlight the need for drug dosing software to be user centered and adaptable to the needs and workflow of end users. Continuous engagement with stakeholders on tool usability, training, and education is needed to promote the implementation in practice.
Publisher: Elsevier BV
Date: 03-2018
DOI: 10.1016/J.AHJ.2017.12.007
Abstract: The optimal long-term antithrombotic regimen for patients after successful catheter-based atrial fibrillation (AF) ablation is not well defined. Presently, practice variation exists, and the benefits of oral anticoagulation over antiplatelet therapy across the entire spectrum of stroke risk profile remain undefined in the postablation population. To date, there are no randomized trials to inform clinicians on this therapeutic question. The objective was to assess whether rivaroxaban is superior to acetylsalicylic acid (ASA) in reducing the risk of clinically overt stroke, systemic embolism, or covert stroke among patients without apparent recurrent atrial arrhythmias for at least 1 year after their most recent AF ablation procedure. A prospective, multicenter, open-label, randomized trial with blinded assessment of outcomes is under way (NCT02168829). Atrial fibrillation patients with at least 1 stroke risk factor (as defined by the CHA The OCEAN trial is a multicenter randomized controlled trial evaluating 2 antithrombotic treatment strategies for patients with risk factors for stroke after apparently successful AF ablation. We hypothesize that rivaroxaban will reduce the occurrence of clinically overt stroke, systemic embolism, and covert stroke when compared with ASA alone.
Publisher: Springer International Publishing
Date: 2016
Publisher: Elsevier BV
Date: 10-2023
Publisher: Informa UK Limited
Date: 2013
Publisher: Editora Blucher
Date: 12-2021
DOI: 10.5151/EAD2021-186
Publisher: SAGE Publications
Date: 06-2006
Publisher: Springer Science and Business Media LLC
Date: 26-11-2017
Publisher: JMIR Publications Inc.
Date: 29-03-2023
Abstract: his co-design research method details the iterative process developed to identify health professional recommendations for the graphical user interface (GUI) of an artificial intelligence (AI)–enabled risk prediction tool. Driving the decision to include a co-design process is the belief that choices regarding the aesthetic and functionality of an intervention are best made by its intended users and that engaging these users in its design will promote the tool’s adoption and use. he aim of this research is to identify health professional design and uptake recommendations for the GUI of an AI-enabled predictive risk tool. e will hold 3 research phases, each consisting of 2 workshops with health professionals, between mid-2023 and mid-2024. A total of 6 health professionals will be sought per workshop, resulting in a total enrollment of 36 health professionals at the conclusion of the research. A total of 7 workshop activities have been scheduled across the 3 workshops these include context of use, notifiers, format, AI survey–Likert, prototype, AI survey–written, and testing. The first 6 of these activities will be repeated in each workshop to enable the iterative development and refinement of GUI. The last activity (testing) will be performed in the final workshop to examine health professionals’ thoughts on the final GUI iteration. Qualitative and quantitative results data will be produced from tasks in each research activity. Qualitative data will be examined through inductive thematic analysis or deductive thematic analysis in accordance with the Nonadoption, Abandonment, and Challenges to the Scale-up, Spread, and Sustainability (NASSS) framework visual data will be examined in accordance with “framework of interactivity ” and quantitative data will be examined using descriptive statistics. roject registration with the Australia and New Zealand Clinical Trial Registry has been requested (#384098). Finalized design recommendations are expected in early to mid-2024, with a results manuscript to be submitted in mid-2024. This research method has human research ethics approval from the South Australian Department of Health and Wellbeing (#2022/HRE00131) as well as from the Human Research Ethics Committee of the University of South Australia (application ID#204143). nderstanding whether an intervention is needed in a particular situation is just the start designing an intervention so that it is used within that situation is paramount. This co-design process engages end users to create a GUI that includes the aesthetic and functional details they need in a manner that aligns with their existing work practices. Indeed, interventions that fail to do this may be disliked, and at worst, they may be dangerous. RR1-10.2196/47717
Publisher: Cambridge University Press (CUP)
Date: 14-02-2023
DOI: 10.1017/S136898002200252X
Abstract: Non-communicable diseases (NCD) such as CVD and type 2 diabetes mellitus are major contributors to the burden of disease. NCD are largely driven by modifiable lifestyle factors including poor diet and insufficient physical activity, and consequently, prevention is a public health priority. Although diet and physical activity levels can be improved via lifestyle interventions, long-term adherence to such interventions remains low, which limits their effectiveness. Thus, it is critical to identify the underlying mechanisms that challenge uptake and adherence to such interventions. The current commentary discusses an important, but underexplored, psychological driver of poor adherence to lifestyle interventions, namely, future discounting, which describes the tendency to prefer smaller, short-term rewards over larger, long-term rewards. For ex le, in the nutrition domain, future discounting refers to valuing the immediate reward of excessive intake of energy-dense, nutrient-poor, discretionary foods high in salt, sugar, and saturated fat, and insufficient intake of low-energy, nutrient-dense, whole foods such as vegetables. Prominent theoretical models propose that excessive future discounting is a major contributor to the development of unhealthy lifestyle behaviours. Furthermore, a vast body of evidence suggests that future discounting plays a key role in risk of NCD. Thus, the evidence to date supports the idea that future discounting is an important multi-behaviour target for supporting lifestyle behaviour change however, this approach has been largely neglected in preventive health efforts. Furthermore, this commentary discusses promising techniques (e.g. Episodic Future Thinking) for disrupting future discounting to promote improved adherence to lifestyle interventions aimed at reducing NCD risk.
Publisher: Public Library of Science (PLoS)
Date: 07-07-2022
DOI: 10.1371/JOURNAL.PDIG.0000069
Abstract: Many middle aged and older people will need to adapt or modify their home in order to age in place. Arming older people and their families with the knowledge and tools to assess their home and plan simple modifications ahead of time will decrease reliance on professional assessment. The objective of this project was to co-design a tool which enables people to assess their own home environment and make future plans for ageing in the home. We recruited members of the public who were aged 60 or older to attend a series of two co-design workshops. Thirteen participants worked through a series of discussions and activities including appraising different types of tools available and mapping what a digital health tool might look like. Participants had a good understanding of the main types of home hazards in their own homes and the types of modifications which may be useful. Participants believed the concept of the tool would be worthwhile and identified a number of features which were important including a checklist, ex les of good design which was both accessible and aesthetically pleasing and links to other resources such as websites which provide advice about to make basic home improvements. Some also wanted to share the results of their assessment with family or friends. Participants highlighted that features of the neighbourhood, such as safety and proximity to shops and cafes, were also important when considering the suitability of their home for ageing in place. Findings will be used to develop a prototype for usability testing.
Publisher: MDPI AG
Date: 23-09-2021
DOI: 10.3390/PH14100954
Abstract: Host cell invasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by the interaction of the viral spike protein (S) with human angiotensin-converting enzyme 2 (ACE2) through the receptor-binding domain (RBD). In this work, computational and experimental techniques were combined to screen antimalarial compounds from different chemical classes, with the aim of identifying small molecules interfering with the RBD-ACE2 interaction and, consequently, with cell invasion. Docking studies showed that the compounds interfere with the same region of the RBD, but different interaction patterns were noted for ACE2. Virtual screening indicated pyronaridine as the most promising RBD and ACE2 ligand, and molecular dynamics simulations confirmed the stability of the predicted complex with the RBD. Bio-layer interferometry showed that artemisone and methylene blue have a strong binding affinity for RBD (KD = 0.363 and 0.226 μM). Pyronaridine also binds RBD and ACE2 in vitro (KD = 56.8 and 51.3 μM). Overall, these three compounds inhibit the binding of RBD to ACE2 in the μM range, supporting the in silico data.
Publisher: UNISINOS - Universidade do Vale do Rio Dos Sinos
Date: 09-04-2021
Abstract: The recent global experience of COVID-19 has problematized the face-to-face co-design process and forced co-design researchers and practitioners to rethink the process of collaboration that typically takes place in a co-design workshop. This paper considers how we might continue to co-design when physical proximity is not possible. Recognising that technology has long played a role in co-design practice, we argue that to date, the technologically mediated experience of co-design has been largely based on the assumption of replicating the physical and embodied experience of the co-design workshop. Rather than accepting the deficit culture implied through the curtailing of much of the conventional face-to-face activities we associate with co-design, this paper reports on proactive research into novel possibilities for continuing collaborative research work through the concept of ‘low-contact co-design’. A series of proprietary visual models that explore a range of spatiotemporal conditions within which co-design practices can occur are presented. Opportunities for engaging with new communities, and in new processes are highlighted and a spatiotemporal framework for planning co-design processes is presented.
Publisher: Centre for Design Innovation (SUT) and Lab4Living: Art & Design Research Centre
Date: 2018
Publisher: Informa UK Limited
Date: 28-07-2017
Publisher: Policy Press
Date: 26-02-2020
Publisher: Springer International Publishing
Date: 2014
Publisher: JMIR Publications Inc.
Date: 31-08-2023
DOI: 10.2196/47717
Abstract: This co-design research method details the iterative process developed to identify health professional recommendations for the graphical user interface (GUI) of an artificial intelligence (AI)–enabled risk prediction tool. Driving the decision to include a co-design process is the belief that choices regarding the aesthetic and functionality of an intervention are best made by its intended users and that engaging these users in its design will promote the tool’s adoption and use. The aim of this research is to identify health professional design and uptake recommendations for the GUI of an AI-enabled predictive risk tool. We will hold 3 research phases, each consisting of 2 workshops with health professionals, between mid-2023 and mid-2024. A total of 6 health professionals will be sought per workshop, resulting in a total enrollment of 36 health professionals at the conclusion of the research. A total of 7 workshop activities have been scheduled across the 3 workshops these include context of use, notifiers, format, AI survey–Likert, prototype, AI survey–written, and testing. The first 6 of these activities will be repeated in each workshop to enable the iterative development and refinement of GUI. The last activity (testing) will be performed in the final workshop to examine health professionals’ thoughts on the final GUI iteration. Qualitative and quantitative results data will be produced from tasks in each research activity. Qualitative data will be examined through inductive thematic analysis or deductive thematic analysis in accordance with the Nonadoption, Abandonment, and Challenges to the Scale-up, Spread, and Sustainability (NASSS) framework visual data will be examined in accordance with “framework of interactivity ” and quantitative data will be examined using descriptive statistics. Project registration with the Australia and New Zealand Clinical Trial Registry has been requested (#384098). Finalized design recommendations are expected in early to mid-2024, with a results manuscript to be submitted in mid-2024. This research method has human research ethics approval from the South Australian Department of Health and Wellbeing (#2022/HRE00131) as well as from the Human Research Ethics Committee of the University of South Australia (application ID#204143). Understanding whether an intervention is needed in a particular situation is just the start designing an intervention so that it is used within that situation is paramount. This co-design process engages end users to create a GUI that includes the aesthetic and functional details they need in a manner that aligns with their existing work practices. Indeed, interventions that fail to do this may be disliked, and at worst, they may be dangerous. PRR1-10.2196/47717
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Location: United Kingdom of Great Britain and Northern Ireland
Start Date: 2012
End Date: 2013
Funder: Arts and Humanities Research Council
View Funded ActivityStart Date: 2012
End Date: 2012
Funder: Arts and Humanities Research Council
View Funded ActivityStart Date: 2013
End Date: 2014
Funder: Arts and Humanities Research Council
View Funded Activity