ORCID Profile
0000-0002-0707-6257
Current Organisation
University of Melbourne
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Research Topics
In Research Link Australia (RLA), "Research Topics" refer to ANZSRC FOR and SEO codes. These topics are either sourced from ANZSRC FOR and SEO codes listed in researchers' related grants or generated by a large language model (LLM) based on their publications.
Top 5 Research Topics
ANZSRC Field of Research (FoR)
Structural Chemistry | Synthesis of Materials | Physical Chemistry (Incl. Structural) | Macromolecular and Materials Chemistry | Solid State Chemistry | Bioinorganic chemistry | Biologically active molecules | Natural Products Chemistry | Physical Chemistry of Materials | Physical Organic Chemistry | Biological And Medical Chemistry | Optical Properties of Materials | Organic Chemical Synthesis | Analytical Spectrometry | Characterisation Of Macromolecules | Nanochemistry and Supramolecular Chemistry | Chemical Characterisation of Materials | Mechanisms Of Reactions | Physical Organic Chemistry | Inorganic chemistry | Sociology and Social Studies of Science and Technology | Organometallic Chemistry | Biological Sciences Not Elsewhere Classified | Analytical Chemistry | Characterisation of Biological Macromolecules | Analytical Spectrometry | Organic Chemistry | Main Group Metal Chemistry | Separation Science | Transition Metal Chemistry | Inorganic Chemistry | Bioinorganic Chemistry | Flow Analysis | F-Block Chemistry | Computer Communications Networks | Structural Chemistry and Spectroscopy | Analytical Chemistry not elsewhere classified |
ANZSRC Socio-Economic Objective (SEO)
Chemical sciences | Treatments (e.g. chemicals, antibiotics) | Human Pharmaceutical Treatments (e.g. Antibiotics) | Expanding Knowledge in the Chemical Sciences | Management of Solid Waste from Energy Activities | Organic Industrial Chemicals (excl. Resins, Rubber and Plastics) | Prevention and treatment of pollution | Other | Workforce Transition and Employment | Other | Communication services not elsewhere classified | Plastic Products (incl. Construction Materials) | Expanding Knowledge in the Biological Sciences
Related Links
Publications
Detection of fish sedimentary DNA in aquatic systems: A review of methodological challenges and future opportunities
Publisher: Wiley
Date: 28-08-2023
DOI: 10.1002/EDN3.467
Abstract: Environmental DNA studies have proliferated over the last decade, with promising data describing the ersity of organisms inhabiting aquatic and terrestrial ecosystems. The recovery of DNA present in the sediment of aquatic systems (sedDNA) has provided short‐ and long‐term data on a wide range of biological groups (e.g., photosynthetic organisms, zooplankton species) and has advanced our understanding of how environmental changes have affected aquatic communities. However, substantial challenges remain for recovering the genetic material of macro‐organisms (e.g., fish) from sediments, preventing complete reconstructions of past aquatic ecosystems, and limiting our understanding of historic, higher trophic level interactions. In this review, we outline the biotic and abiotic factors affecting the production, persistence, and transport of fish DNA from the water column to the sediments, and address questions regarding the preservation of fish DNA in sediment. We identify sources of uncertainties around the recovery of fish sedDNA arising during the sedDNA workflow. This includes methodological issues related to experimental design, DNA extraction procedures, and the selected molecular method (quantitative PCR, digital PCR, metabarcoding, metagenomics). By evaluating previous efforts (published and unpublished works) to recover fish sedDNA signals, we provide suggestions for future research and propose troubleshooting workflows for the effective detection and quantification of fish sedDNA. With further research, the use of sedDNA has the potential to be a powerful tool for inferring fish presence over time and reconstructing their population and community dynamics.
Celastrofurans A-G: Dihydro-β-Agarofurans from the Australian Rainforest Vine Celastrus subspicata and Their Inhibitory Effect on Leucine Transport in Prostate Cancer Cells
Publisher: American Chemical Society (ACS)
Date: 26-05-2017
DOI: 10.1021/ACS.JNATPROD.7B00220
Abstract: Seven new dihydro-β-agarofurans, celastrofurans A-G (1-7), along with two known secondary metabolites, 9β-benzoyloxy-1α-furoyloxydihydro-β-agarofuran (8) and (1R,2R,4R,5S,7R,9S,10R)-2-acetoxy-9-benzoyloxy-1-furoyloxydihydro-β-agarofuran (9), were obtained from the leaves of the Australian rainforest vine, Celastrus subspicata. The structures of the new compounds were determined by detailed spectroscopic (1D/2D NMR) and MS data analysis. The absolute configurations of compounds 1-4 were defined by ECD and single-crystal X-ray diffraction studies. All compounds were found to exhibit inhibitory activity on leucine transport in the human prostate cancer cell line LNCaP with IC
An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0DT02673E
Abstract: A cyclen bearing semicarbazone pendant groups forms complexes with Bi 3+ and Pb 2+ and was radiolabeled with the alpha-emitting radioisotope 213 Bi.
High fluorescence efficiency of intrinsic ligand-free zero-dimensional Cs4PbBr6 particles and microcrystals
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1TC02571F
Abstract: Surface traps are the main defects in the Cs 4 PbBr 6 particles with smaller size, whereas bulk defects dominate in the larger microcrystals.
Hammett Structural Relationships Revealed in Chalcogen-Bonded Co-Crystals of Electron-Rich Pyridines with 4′-Substituted Ebselen Derivatives
Publisher: American Chemical Society (ACS)
Date: 30-08-2023
Protection of Boronic Acids Using a Tridentate Aminophenol ONO Ligand for Selective Suzuki–Miyaura Coupling
Publisher: American Chemical Society (ACS)
Date: 25-01-2023
Norbornene chaotropic salts as low molecular mass ionic organogelators (LMIOGs)
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8SC01798K
Abstract: A humble norbornene functions as an ionic organogelator, forms aqueous biphasic and triphasic systems and assembles to form chiral helices.
Solubilizing core modifications on high-performing benzodithiophene-based molecular semiconductors and their influences on film nanostructure and photovoltaic performance
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9TA00168A
Abstract: Through depth-dependent GIWAXS studies, the solubility of molecular organic semiconductors was found to correlate with π-stacking orientation and photovoltaic performance.
Total Synthesis of Viridiofungins A and B
Publisher: American Chemical Society (ACS)
Date: 22-04-2021
Palladium-Mediated CO2 Extrusion Followed by Insertion of Allenes: Translating Mechanistic Studies to Develop a One-Pot Method for the Synthesis of Alkenes
Publisher: American Chemical Society (ACS)
Date: 20-06-2022
Gallium Fluoride Complexes with Acyclic Bispicolinic Ligands as Potential New Fluorine‐18 Labelled Imaging Agents
Publisher: Wiley
Date: 09-09-2020
A cis-β-iron(iii ) SALPN catalyst for hydrogen atom transfer reductions and olefin cross couplings
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D3OB01085F
Abstract: An inexpensive Fe( iii ) SALPN catalyst for MHAT reactions such as reductions of α,β-unsaturated carbonyl compounds and olefin cross couplings is reported.
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M
Publisher: American Chemical Society (ACS)
Date: 14-12-2019
DOI: 10.1021/ACSCHEMNEURO.8B00613
Abstract: Targeting allosteric sites of the M
Conversion of kinetically stable metal-organic product to thermodynamically stable one approved by thermal treatment and sonochemical reaction
Publisher: Elsevier BV
Date: 03-2020
Highly Efficient Luminescent Solar Concentrators by Selective Alignment of Donor–Emitter Fluorophores
Publisher: American Chemical Society (ACS)
Date: 29-03-2019
Pb⋯X (X = N, S, I) tetrel bonding interactions in Pb(ii ) complexes: X-ray characterization, Hirshfeld surfaces and DFT calculations
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8CE00110C
Abstract: We report the synthesis and X-ray characterization of four new Pb( ii ) complexes of nicotinoylhydrazone and picolinoylhydrazone-based ligands and three different anionic co-ligands (acetate, thiocyanate and iodide) exhibiting relevant tetrel bonding interactions.
Experimental and theoretical investigations into the mechanisms of haliranium ion π-ligand exchange reactions with cyclic alkenes in the gas phase
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1CP04494J
Abstract: Haliranium ion reactivity with cyclic alkenes in the gas phase was investigated by examining how the nature of the halogen (X = Br or I) and the effect of ring strain affected the partitioning between π-ligand exchange and addition.
Multiple Construction of a Hierarchical Nanoporous Manganese(II)-Based Metal–Organic Framework with Active Sites for Regulating N2 and CO2 Trapping
Publisher: American Chemical Society (ACS)
Date: 08-02-2022
Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D2CC06850H
Abstract: Amyloid-β antibodies were modified to incorporate trans -cyclooctene functional groups. Radiolabeled copper-64 probes, which can cross the blood–brain barrier and contain a 1,2,4,5-tetrazine functional group, react with the modified antibodies.
A structural study of p-type A–D–A oligothiophenes: effects of regioregular alkyl sidechains on annealing processes and photovoltaic performances
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9TC05280A
Abstract: Structure–property studies of p-type oligothiophene-based materials linking sidechain substituents, photovoltaic performance and thin-film morphology leading to key design guidelines.
Limitations of conjugated polymers as emitters in triplet–triplet annihilation upconversion
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1MA00684C
Abstract: Triplet–triplet annihilation upconversion performances for poly(phenylene-vinylene) emitters were investigated through a series of copolymers with bulky sidechains.
Frontispiz: Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes
Publisher: Wiley
Date: 05-07-2017
Evidence that π‐ligand exchange reactions of chalcogen iranium ions proceed via Hückel pseudocoarctate transition states
Publisher: Wiley
Date: 16-07-2020
DOI: 10.1002/POC.4111
Multistereocenter-Containing Cyclopentanoids from Ynamides via Oxazolidinone-Controlled Nazarov Cyclization
Publisher: American Chemical Society (ACS)
Date: 13-06-2017
Abstract: Achieving ready-enantioselective access to multistereocenter-containing cyclopentyl rings is an area of great significance to organic synthesis. In this work, we describe a general protocol for accessing multistereocenter-containing cyclopentanoids from simple N-alkynyloxazolidinones (Ox-ynamides). This protocol involves conversion of Ox-ynamides into Ox-activated inyl and aryl vinyl ketones that undergo facile Nazarov cyclization with excellent chemo-, regio-, and stereocontrol. The Ox auxiliary directs all aspects of reactivity and selectivity, both in the electrocyclization and in the subsequent transformations of the resulting oxyallyl intermediate. Stereoinduction in the electrocyclization results from a "coupled-torque" mechanism in which rotation of the Ox group, driven by increasing orbital overlap of the nitrogen lone pair with the incipient oxyallyl cation, is coupled with the rotation of the termini of the pentadienyl cation, favoring a particular direction of conrotatory ring closure (torquoselectivity). The associated lone-pair stabilization of the transition state by Ox promotes cyclization of traditionally resistant substrates, broadening the scope of this asymmetric Nazarov cyclization. The Ox group also facilitates the stereo- and regioselective incorporation of nucleophiles (Nu) and dienes, giving more complex, multistereocenter containing cyclopentanoids. Finally, the Ox group is readily removed and recovered or can be converted into other amine functionalities.
Implantation of Impella CP® left ventricular assist device under the guidance of three-dimensional intracardiac echocardiography.
Publisher: Research Square Platform LLC
Date: 27-04-2020
DOI: 10.21203/RS.3.RS-23212/V1
Abstract: Impella CP® is a percutaneously inserted left ventricular assist device indicated for temporary mechanical cardiac support during high risk percutaneous coronary interventions and for cardiogenic shock. The potential application of Impella has become particularly relevant during the current COVID-19 pandemic, for patients with acute severe heart failure complicating viral illness. Standard implantation of the Impella CP® is performed under fluoroscopic guidance. Positioning of the Impella CP® can be confirmed with transthoracic or transoesophageal echocardiography. We conducted translational study in ovine model describing an alternative approach to guide implantation of the Impella CP® using two-dimensional and three-dimensional intracardiac echocardiography. This new technique can be useful in selected groups of patients when fluoroscopy, transthoracic and transoesophageal echocardiography is deemed inapplicable or limited for epidemiological or clinical reasons. Intracardiac three-dimensional echocardiography is a feasible alternative to the traditional techniques for implantation of an Impella device.
Thermal conversion of a pyridine solvate to a de-solvate facilitated by rearrangement of chalcogen bonds. The solvate and non-solvate structures of N-(2-nitro-4-(3-oxobenzo[d][1,2]selenazol-2(3H)-yl)phenyl)picolinamide
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0CE00662A
Abstract: Heating the pyridine solvate 1 .pyridine from 90–110 °C results in transformation to the crystalline non-solvate.
Catalyst Luminescence Exploited as an Inherent In Situ Probe of Photoredox Catalysis
Publisher: Wiley
Date: 22-10-2020
Experimental and DFT Studies on the Identity Exchange Reactions between Phenyl Chalcogen Iranium Ions and Alkenes
Publisher: American Chemical Society (ACS)
Date: 12-09-2019
Abstract: The gas-phase ion-molecule identity exchange reactions of phenyl chalcogen iranium ions with alkenes have been examined experimentally in a linear ion trap mass spectrometer by isotope labeling experiments. The nature of both the alkene and the chalcogen play crucial roles, with the bimolecular rates for π-ligand exchange following the order: [PhTe(
Phytochemical Profiling and Biological Testing of the Constituents of the Australian Plant Haemodorum brevisepalum
Publisher: American Chemical Society (ACS)
Date: 15-11-2021
DOI: 10.1021/ACS.JNATPROD.1C00509
Abstract: Phytochemical profiling was undertaken on the crude extracts of the bulbs, stems, and the fruits of
Complex interplay of hydrogen bonding, halogen bonding and π-interactions in methyl 2-(7-chloro-1H-pyrazolo[3,4-b]quinolin-1-yl)acetate: Synthesis, X-ray crystallography, energetic features and anti-u
Publisher: Elsevier BV
Date: 09-2023
Total Synthesis and Stereochemical Reassignment of Citrafungin A
Publisher: American Chemical Society (ACS)
Date: 14-11-2019
DOI: 10.1021/ACS.ORGLETT.9B03830
Abstract: The stereoselective 12-step total synthesis of the reassigned structure for citrafungin A (
Synthesis and Solvatochromic Behavior of Zwitterionic Donor–Bridge–Acceptor Systems with Oligo(p-phenylene) Spacers
Publisher: Georg Thieme Verlag KG
Date: 04-2021
Abstract: Oligo(p-phenylene)s with a donor phenol group and an acceptor pyridinium moiety separated by one and two p-phenylene units were synthesized by the linear iterative Suzuki–Miyaura coupling method using aryl nonaflates as effective coupling reagents. Zwitterionic forms of these push–pull molecules were generated upon deprotonation of the phenol leading to large redshifts in absorbance maxima. UV-vis absorbance studies also revealed strong dependence of the band position on solvent polarity: a smooth bathochromic shift can be observed with the decrease of the solvent polarity. The molecule with one p-phenylene bridging unit showed the strongest solvatochromic characteristics in the series, spanning the range of 167 nm while moving from polar water to less polar N,N-dimethylformamide. The magnitude of this shift was close to Reichardt's dye — one of the most solvatochromic organic dyes known.
Optimising molecular rotors to AIE fluorophores for mitochondria uptake and retention
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0CC06411D
Abstract: AIE-active molecular rotors for mitochondria imaging with improved uptake and retention in both live and fixed cells.
Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes
Publisher: Wiley
Date: 23-03-2017
Aromaticity and antiaromaticity in monoheterocyclic three‐membered rings: Application of natural bond orbital theory
Publisher: Wiley
Date: 23-11-2023
DOI: 10.1002/POC.4463
Abstract: Using natural bond orbital theory, aromatic stabilization energies (NBO‐ASEs) were calculated for neutral and cationic monoheterocyclic three‐membered rings C 2 H 2 X(R) n (X = group 14–17 elements of rows 3–5 R = F, H or SiH 3 and n = 0–2). Generally, there was a decrease in the (anti)aromatic nature of the molecule moving down the group as either the stabilizing orbital overlap (aromaticity) or destabilizing orbital interactions (antiaromaticity) were reduced due to larger atoms inducing longer bonds. (Anti)aromatic trends were supported with dissected nucleus independent chemical shift NICS(0) π , zz values ( R 2 = 0.94) and also by comparison of NBO‐ASEs to literature values for a selection of larger systems including benzene, cyclobutadiene, and the cyclopentadienyl anion. Comparisons are made to other studies that have used a range of approaches to study (anti)aromaticity in some of these molecules, and it was found that non‐dissected NICS values and homodesmotic equations often gave significantly overestimated if not misleading results.
Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A1 Receptor in Living Cells
Publisher: American Chemical Society (ACS)
Date: 16-03-2021
Identification of Anthelmintic Bishomoscalarane Sesterterpenes from the Australian Marine Sponge Phyllospongia bergquistae and Structure Revision of Phyllolactones A–D
Publisher: American Chemical Society (ACS)
Date: 21-06-2022
DOI: 10.1021/ACS.JNATPROD.2C00229
Abstract: High-throughput screening of the NatureBank marine extract library (7616 s les) identified an extract derived from the Australian marine sponge
Comprehensive Synthesis of Substrates, Intermediates, and Products of the Sulfoglycolytic Embden-Meyerhoff-Parnas Pathway.
Publisher: American Chemical Society (ACS)
Date: 11-02-2019
Abstract: Sulfoglycolysis is a metabolic pathway dedicated to the catabolism of the sulfosugar sulfoquinovose (SQ) into smaller organosulfur fragments. An estimated 10 billion tonnes of SQ fluxes through sulfoglycolysis pathways each year, making it a significant aspect of the biogeochemical sulfur cycle. Delineating the molecular details of sulfoglycolysis requires authentic s les of the various metabolites in these pathways. To this end, we have established chemical and chemoenzymatic methods for the synthesis of the key organosulfur metabolites sulfoquinovosylglycerol, SQ (also in
Tungsten Ligand-Based Sulfur-Atom-Transfer Catalysts: Synthesis, Characterization, Sustained Anaerobic Catalysis, and Mode of Aerial Deactivation
Publisher: American Chemical Society (ACS)
Date: 17-11-2020
Reactions of Thiiranium and Sulfonium Ions with Alkenes in the Gas Phase
Publisher: American Chemical Society (ACS)
Date: 22-07-2019
Abstract: Ion-molecule reactions between thiiranium ion
Seleniranium Ions Undergo π-Ligand Exchange via an Associative Mechanism in the Gas Phase
Publisher: American Chemical Society (ACS)
Date: 02-06-2017
Abstract: Collision-induced dissociation mass spectrometry of the ammonium ions 4a and 4b results in the formation of the seleniranium ion 5, the structure and purity of which were verified using gas-phase infrared spectroscopy coupled to mass spectrometry and gas-phase ion-mobility measurements. Ion-molecule reactions between the ion 5 (m/z = 261) and cyclopentene, cyclohexene, cycloheptene, and cyclooctene resulted in the formation of the seleniranium ions 7 (m/z = 225), 6 (m/z = 239), 8 (m/z = 253), and 9 (m/z = 267), respectively. Further reaction of seleniranium 6 with cyclopentene resulted in further π-ligand exchange giving seleniranium ion 7, confirming that direct π-ligand exchange between seleniranium ion 5 and cycloalkenes occurs in the gas phase. Pseudo-first-order kinetics established relative reaction efficiencies for π-ligand exchange for cyclopentene, cyclohexene, cycloheptene. and cyclooctene as 0.20, 0.07, 0.43, and 4.32. respectively. DFT calculations at the M06/6-31+G(d) level of theory provide the following insights into the mechanism of the π-ligand exchange reactions the cycloalkene forms a complex with the seleniranium ion 5 with binding energies of 57 and 62 kJ/mol for cyclopentene and cyclohexene, respectively, with transition states for π-ligand exchange having barriers of 17.8 and 19.3 kJ/mol for cyclopentene and cyclohexene, respectively.
Synthesis of acyloin natural products by Mukaiyama hydration
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2OB00651K
Abstract: The preparation of Co( ii ) and Co( iii ) SALPN type catalysts for the Mukaiyama hydration of enones, and their application to the synthesis of acyloin natural products is described. An acyloin rearrangement was key to the success of this approach.
A multifunctional surfactant catalyst inspired by hydrolases
Publisher: American Association for the Advancement of Science (AAAS)
Date: 03-04-2020
Abstract: Enzyme-inspired catalysis using self-assembled hiphiles mimic and localize multiple chemical units common to hydrolases.
Experimental and theoretical investigations into the manifestation of the γ-effect in 2- and 4-[2-silylethyl)]pyridines and pyridinium ions
Publisher: Elsevier BV
Date: 11-2021
On the importance of π-hole spodium bonding in tricoordinated HgII complexes
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0DT03938A
Abstract: The synthesis and X-ray characterization of two new tri-coordinated Hg complexes where the planar Hg atom participates in π-hole spodium bonding.
Competitive Triplet Formation and Recombination in Crystalline Films of Perylenediimide Derivatives: Implications for Singlet Fission
Publisher: American Chemical Society (ACS)
Date: 05-05-2020
Potential Diagnostic Imaging of Alzheimer’s Disease with Copper-64 Complexes That Bind to Amyloid-β Plaques
Publisher: American Chemical Society (ACS)
Date: 20-02-2019
DOI: 10.1021/ACS.INORGCHEM.8B03466
Abstract: Amyloid-β plaques, consisting of aggregated amyloid-β peptides, are one of the pathological hallmarks of Alzheimer's disease. Copper complexes formed using positron-emitting copper radionuclides that cross the blood-brain barrier and bind to specific molecular targets offer the possibility of noninvasive diagnostic imaging using positron emission tomography. New thiosemicarbazone-pyridylhydrazone based ligands that incorporate pyridyl-benzofuran functional groups designed to bind amyloid-β plaques have been synthesized. The ligands form stable complexes with copper(II) ( K
Strong detection of the CMB lensing and galaxy weak lensing cross-correlation from ACT-DR4,PlanckLegacy, and KiDS-1000
Publisher: EDP Sciences
Date: 05-2021
DOI: 10.1051/0004-6361/202039975
Abstract: We measured the cross-correlation between galaxy weak lensing data from the Kilo Degree Survey (KiDS-1000, DR4) and cosmic microwave background (CMB) lensing data from the Atacama Cosmology Telescope (ACT, DR4) and the Planck Legacy survey. We used two s les of source galaxies, selected with photometric redshifts, (0.1 z B 1.2) and (1.2 z B 2), which produce a combined detection significance of the CMB lensing and weak galaxy lensing cross-spectrum of 7.7 σ . With the lower redshift galaxy s le, for which the cross-correlation was detected at a significance of 5.3 σ , we present joint cosmological constraints on the matter density parameter, Ω m , and the matter fluctuation litude parameter, σ 8 , marginalising over three nuisance parameters that model our uncertainty in the redshift and shear calibration as well as the intrinsic alignment of galaxies. We find our measurement to be consistent with the best-fitting flat ΛCDM cosmological models from both Planck and KiDS-1000. We demonstrate the capacity of CMB weak lensing cross-correlations to set constraints on either the redshift or shear calibration by analysing a previously unused high-redshift KiDS galaxy s le (1.2 z B 2), with the cross-correlation detected at a significance of 7 σ . This analysis provides an independent assessment for the accuracy of redshift measurements in a regime that is challenging to calibrate directly owing to known incompleteness in spectroscopic surveys.
Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes
Publisher: Wiley
Date: 23-03-2017
Abstract: A Zn
Molecular tweezers with a rotationally restricted linker and freely rotating porphyrin moieties
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8OB00944A
Abstract: The different host–guest behaviour of non-interconvertible bis-porphyrin tweezer isomers was examined, contributing to ongoing discussions regarding rigidity/flexibility and preorganisation in synthetic receptors.
Correction to Phytochemical Profiling and Biological Activity of the Australian Carnivorous Plant, Drosera magna
Publisher: American Chemical Society (ACS)
Date: 23-06-2021
Solid–Liquid Conversion and Carbon Dioxide Storage in a Calcium-Based Metal–Organic Framework with Micro- and Nanoporous Channels
Publisher: American Chemical Society (ACS)
Date: 24-10-2019
Computational Study of Two Three-Dimensional Co(II)-Based Metal–Organic Frameworks as Quercetin Anticancer Drug Carriers
Publisher: American Chemical Society (ACS)
Date: 25-10-2022
Comatulins A–E, Taurine-Conjugated Anthraquinones from the Australian Crinoid Comatula rotalaria
Publisher: American Chemical Society (ACS)
Date: 06-2020
The mechanochemical conversion of potassium coordination polymer nanostructures to interpenetrated sodium coordination polymers with halogen bond, metal–carbon and metal–metal interactions
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9CE01861A
Abstract: Two new Na and K coordination polymers with halogen bond, metallophilic and hydrogen bonding interactions were synthesized. These two compounds were synthesized sonochemically and solid-state conversions of them to each other were investigated.
Automated synthesis of 18F radiolabelled indole containing Oncrasin-like molecules; a comparison of iodonium salts and boronic ester chemistry
Publisher: Springer Science and Business Media LLC
Date: 09-11-2020
DOI: 10.1186/S41181-020-00104-X
Abstract: Oncrasin-1 is a small molecule which was identified from a screen of KRAS mutant cancer cells and has shown specificity for KRAS mutant cell killing. We aimed to develop a radiolabelled form of Oncrasin-1 to enable in-vivo imaging of mutant KRAS expression in malignant tumours. This work outlines the synthesis of 3 fluorinated derivatives and development of iodonium salt and boronic ester precursors for radiolabelling with the 18 F isotope. In our hands, synthesis of iodonium salts were not easily accessible due to the 3-carbaldehyde indole structure being preferentially oxidized by conditions required for iodonium salt formation, rather than benzyl iodide. Synthesis and radiolabelling of boronic acid pinacol ester precursors were successful, with the products being obtained in yields of 10.76% ± 0.96% ( n = 5), 14.7% ±8.58% ( n = 3) and 14.92% ±3.9% (n = 3) for 18 F KAM001, 18 F KAM002 and 18 F KAM003 respectively, with radiochemical purity of greater than 99%. The successful synthesis of these tracers has been undertaken utilizing boronic ester radio-fluorination methods and will allow for investigation of Oncrasin based molecules as potential diagnostics for cancers expressing mutant KRAS protein.
Synthesis of the Alkylsulfonate Metabolites Cysteinolic Acid, 3-Amino-2-hydroxypropanesulfonate, and 2,3-Dihydroxypropanesulfonate
Publisher: American Chemical Society (ACS)
Date: 24-02-2022
Abstract: Chiral hydroxy- and aminohydroxysulfonic acids are widespread in the marine and terrestrial environment. Here we report simple methods for the synthesis of d- and l-cysteinolic acid (from (Boc-d-Cys-OH)
CHAL336 Benchmark Set: How Well Do Quantum-Chemical Methods Describe Chalcogen-Bonding Interactions?
Publisher: American Chemical Society (ACS)
Date: 21-04-2021
Synthesis, crystal structure, Hirshfeld surface analyses, antimicrobial activity, and thermal behavior of some novel nanostructure hexa‐coordinated Cd(II) complexes: Precursors for CdO nanostructure
Publisher: Wiley
Date: 24-02-2021
DOI: 10.1002/AOC.6181
Phytochemical Profiling and Biological Activity of the Australian Carnivorous Plant, Drosera magna
Publisher: American Chemical Society (ACS)
Date: 25-02-2021
Experimental evidence of chalcogen bonding at oxygen
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9CC09896H
Abstract: An o -nitro-O-aryl oxime was observed to exhibit a short O⋯O contact, which exhibited characteristics consistent with a chalcogen bond.
Rhenium and Technetium-oxo Complexes with Thioamide Derivatives of Pyridylhydrazine Bifunctional Chelators Conjugated to the Tumour Targeting Peptides Octreotate and Cyclic-RGDfK
Publisher: American Chemical Society (ACS)
Date: 02-08-2017
Synthesis of Alkyl Citrates (−)-CJ-13,981, (−)-CJ-13,982, and (−)-L-731,120 via a Cyclobutene Diester
Publisher: American Chemical Society (ACS)
Date: 28-06-2018
DOI: 10.1021/ACS.ORGLETT.8B01665
Abstract: An efficient and step-economic new approach to alkyl citrate natural products from a cyclobutene diester is presented. The key sequence involves a formal [2 + 2]-cycloaddition of a silylketene acetal with dimethylacetylene dicarboxylate to provide the cyclobutene diester 14 with 4.5:1 stereoselectivity. Exposure of diester 14 in acidic methanol effected a hydrolysis, intramolecular oxy-Michael reaction, and cyclobutanone methanolysis cascade to give the triester 15. Iodination and elimination then afforded a key alkyl citrate alkene intermediate, which was converted into the natural products (-)-CJ-13,982 (1), (-)-CJ-13,981 (2), and (-)-L-731,120 (3) via a cross-metathesis and subsequent reduction.
Design and construction of Zn(II) coordination polymers made by pincer type pyridine-hydrazine based ligands
Publisher: Elsevier BV
Date: 12-2019
Simulating chalcogen bonding using molecular mechanics: a pseudoatom approach to model ebselen
Publisher: Springer Science and Business Media LLC
Date: 24-02-2022
DOI: 10.1007/S00894-021-05023-5
Abstract: The organoselenium compound ebselen has recently been investigated as a treatment for COVID-19 however, efforts to model ebselen in silico have been h ered by the lack of an efficient and accurate method to assess its binding to biological macromolecules. We present here a Generalized Amber Force Field modification which incorporates classical parameters for the selenium atom in ebselen, as well as a positively charged pseudoatom to simulate the σ -hole, a quantum mechanical phenomenon that dominates the chemistry of ebselen. Our approach is justified using an energy decomposition analysis of a number of density functional theory–optimized structures, which shows that the σ -hole interaction is primarily electrostatic in origin. Finally, our model is verified by conducting molecular dynamics simulations on a number of simple complexes, as well as the clinically relevant enzyme SOD1 (superoxide dismutase), which is known to bind to ebselen.
Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography
Publisher: Royal Society of Chemistry (RSC)
Date: 2023
DOI: 10.1039/D2CC04813B
Abstract: A fluorine-18 labelled probe was developed to target bromodomain and extraterminal (BET) proteins for molecular imaging of cancer with positron emission tomography.
Asymmetric synthesis of multiple quaternary stereocentre-containing cyclopentyls by oxazolidinone-promoted Nazarov cyclizations
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8SC00031J
Abstract: Ox -activated inyl ketones undergo torquoselective Nazarov cyclization to give cyclopentanoids containing up to three new contiguous quaternary (4°) stereocentres.
Two-Fold Homointerpenetrated Metal–Organic Framework with the Potential for Anticancer Drug Loading Using Computational Simulations
Publisher: American Chemical Society (ACS)
Date: 07-10-2021
An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7OB01121K
Abstract: A unprecedented base-induced trimerization of bromovinylsulfone 1 afforded the cyclohexene 6 as a single diastereoisomer.
Selective Synthesis of C1-Symmetric BINOL-phosphates and P-chiral Phosphoramides Using Directed ortho-Lithiation
Publisher: American Chemical Society (ACS)
Date: 27-08-2021
Highly Fluorescent Molecularly Insulated Perylene Diimides: Effect of Concentration on Photophysical Properties
Publisher: American Chemical Society (ACS)
Date: 18-09-2017
Design of Calcium-Based Metal–Organic Frameworks by the Solvent Effect and Computational Investigation of Their Potential as Drug Carriers
Publisher: American Chemical Society (ACS)
Date: 08-04-2022
Oxidative damage of proline residues by nitrate radicals (NO3˙): a kinetic and product study
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0OB01337D
Abstract: Kinetic studies in acetonitrile revealed that proline residues in peptides are considerably protected against radical-induced oxidative damage by the neighbouring peptide bonds, compared with the single amino acid.
Effect of structural features on the stability and bactericidal potential of two cadmium coordination polymers
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1CE00979F
Abstract: Two mixed ligand Cd( ii ) coordination polymers have been synthesized using three methods by in situ decarboxylation of phenylmalonic acid. CPs were screened for their antibacterial activities and the influence of structural properties was studied.
Coordination polymers fabricated from Cd(NO3)2 and N,N′,O-pincer-type isonicotinoylhydrazone-based polytopic ligands – an insight from experimental and theor
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2CE00294A
Abstract: Three new Cd( ii ) coordination polymers based on isonicotinohydrazide ligands ( HL I , HL II ) differing in the presence of a methyl unit have been obtained and extensively characterized by experimental and computational approaches.
An effectivecis-β-octahedral Mn(iii ) SALPN catalyst for the Mukaiyama–Isayama hydration of α,β-unsaturated esters
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9CC03921J
Abstract: Two cis -β-Mn III SALPN catalysts were synthesised and tested in the Mukaiyama – Isayama hydration of α,β-unsaturated esters.
Structure–reactivity correlations of the abnormal Beckmann reaction of dihydrolevoglucosenone oxime
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7OB02499A
Abstract: Structural, spectroscopic and computational studies of a series of oximes reveals ground state structural manifestations relevant to the reaction coordinate for the Beckmann rearrangement (normal Beckmann) and Beckmann fragmentation (abnormal Beckmann).
Irreversible exchange of potassium with thallium in coordination polymer nanostructures upon solid-state Mechanochemical process
Publisher: Elsevier BV
Date: 06-2018
Novel cadmium (II) N2O2‐Schiff base compounds: X‐ray crystal structure, Hirshfeld surface study, thermal behavior, antimicrobial, DNA cleavage power, antioxidant, and cytotoxicit
Publisher: Wiley
Date: 03-08-2023
DOI: 10.1002/AOC.7202
Abstract: A new N 2 O 2 ‐tetradentate Schiff base ligand entitled as N,N′‐((ethane‐1,2‐diybis [oxy])bis (ethan‐2,1‐diyl))bis(3‐(4‐methoxyphenyl)prop‐2‐en‐1‐imine was prepared by direct reaction between 3‐(4‐methoxyphenyl)‐2‐propenal and 1,8‐diamino‐3,6‐dioxaoctane. After characterization of the ligand, some novel cadmium coordination compounds formulated as CdLX 2 (X: Cl − , Br − , I − , N 3 − , SCN − and NO 3 − ) were synthesized and characterized by physical and spectral techniques. Typically crystal structure of cadmium nitrate coordination compound was determined suggesting crystallization in monoclinic system (with space group of I 2/a ) and a coordination geometry of square anti‐prism around the Cd (II) ion. Moreover, CdLBr 2 and CdLI 2 compounds were prepared in nanostructured dimensions by sonochemical method confirmed by SEM, EDX, and XRD techniques. In continuation, thermal behavior investigation of the compounds including thermal stabilities, thermal decomposition steps, and thermo‐kinetic parameters was performed based on Coats‐Redfern equations from room temperature to 900 °C. Furthermore, all the compounds were subjected to bioassay against two Gram‐positive bacteria of Staphylococcus aureus and Bacillus subtilis , two Gram‐negative bacteria of Pseudomonas aeruginosa and Escherichia coli, and two fungal strains of Aspergillus oryzae and Candida albicans . The results showed that all the synthesized compounds act well as antimicrobial agents. DNA cleavage power of the materials was also evaluated using extracted DNA from E. coli bacterium. The cytotoxic activities of some compounds were investigated against the prostate cancer cell lines (PC3) and human umbilical vein endothelial cells (HUVEC) (as normal cells) by MTT assay and nitric oxide level evaluation method as compared with cis ‐platin confirming anti‐cancer effects of them. Finally, the antioxidant properties of the N 2 O 2 ‐ligand and its cadmium coordination compounds were examined by DPPH and FRAP methods suggesting all the compounds have good antioxidant activity as compared with standard s les.
FRET-enhanced photoluminescence of perylene diimides by combining molecular aggregation and insulation
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/D0TC02108C
Abstract: S les containing both molecularly insulated and aggregated perylene diimides at high concentration (140 mM) in polymer matrix showed very high photoluminescence quantum yield (85%) as a result of efficient energy transfer.
Structural characterization and gas-phase studies of the [Ag10H8(L)6]2+ nanocluster dication
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C9NR08321A
Abstract: The structure of a large dicationic silver hydride nanocluster was determined by X-ray crystallography. Pathways to the gas-phase liberation of hydrogen have been identified.
Synthesis and characterisation of new antimalarial fluorinated triazolopyrazine compounds
Publisher: Beilstein Institut
Date: 31-01-2023
DOI: 10.3762/BJOC.19.11
Abstract: Nine new fluorinated analogues were synthesised by late-stage functionalisation using Diversinate™ chemistry on the Open Source Malaria (OSM) triazolopyrazine scaffold (Series 4). The structures of all analogues were fully characterised by NMR, UV and MS data analysis three triazolopyrazines were confirmed by X-ray crystal structure analysis. The inhibitory activity of all compounds against the growth of the malaria parasite Plasmodium falciparum (3D7 and Dd2 strains) and the cytotoxicity against a human embryonic kidney (HEK293) cell line were tested. Some of the compounds demonstrated moderate antimalarial activity with IC 50 values ranging from 0.2 to µM none of the compounds displayed any cytotoxicity against HEK293 cells at 80 µM. Antimalarial activity was significantly reduced when C-8 of the triazolopyrazine scaffold was substituted with CF 3 and CF 2 H moieties, whereas incorporation of a CF 2 Me group at the same position completely abolished antiplasmodial effects.
Polar protic solvent-trapping polymorphism of the HgII-hydrazone coordination polymer: experimental and theoretical findings
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7CE00626H
An icosanuclear silver(I) cluster supported by bis(thiosemicarbazonato) ligands
Publisher: CSIRO Publishing
Date: 10-03-2022
DOI: 10.1071/CH21335
Abstract: The synthesis and structural characterisation of an icosanuclear silver(I) cluster complex is reported here. The complex includes twenty silver(I) ions supported by eighteen bis(thiosemicarbazonato) ligands. The cluster of silver(I) ions involves several close Ag⋯Ag contacts suggesting some degree of argentophilic interactions and the bis(thiosemicarbazonato) ligands are present in three different conformations highlighting the ability of thiosemicarbazone ligands to coordinate to metal ions in different modes.
New insights into chalcogen bonding provided by co-crystal structures of benzisoselenazolinone derivatives and nitrogen bases
Publisher: Royal Society of Chemistry (RSC)
Date: 2019
DOI: 10.1039/C8CE01853G
Abstract: A number of derivatives of benzisoselenazolinones, including the drug ebselen, have been synthesized, and their interactions with various nitrogen bases characterized through X-ray crystallography.
Exciton Dynamics of Photoexcited Pendant Porphyrin Polymers in Solution and in Thin Films
Publisher: American Chemical Society (ACS)
Date: 26-11-2018
Abstract: Several new polymers with rotatable zinc porphyrin pendants have been synthesized and their optical spectroscopic and photophysical properties, including upconversion efficiencies, determined in both fluid solution and thin films. Comparisons made with the β-substituted zinc tetraphenylporphyrin monomers and ZnTPP itself reveal that the yield of triplets resulting from either Q-band or Soret-band excitation of the polymers is surprisingly small. A detailed kinetic analysis of the fluorescence decays and transient triplet absorptions of the substituted monomers and their corresponding polymers reveals that this phenomenon is due to two parallel internal singlet quenching processes assigned to transient intrachain excimer formation. Consequently, the yields of upconverted S
The role of conformational heterogeneity in the excited state dynamics of linked diketopyrrolopyrrole dimers
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1CP00541C
Abstract: Conformational heterogeneity leads to different excited state relaxation pathways in flexibly-linked DPP-dimers.
Synthesis of the C-Terminal Macrocycle of Asperipin-2a
Publisher: American Chemical Society (ACS)
Date: 06-03-2019
DOI: 10.1021/ACS.ORGLETT.9B00488
Abstract: A synthetic approach to the C-terminal macrocycle of asperipin-2a is presented. Two epimers were prepared, possessing R- and S-configurations at the β-position of Tyr
Spectroscopic and Dynamic Properties of Electronically Excited Pendant Porphyrin Polymers with Backbones of Differing Flexibility
Publisher: American Chemical Society (ACS)
Date: 15-12-2020
Electronic and Steric Effects on the Reactivity of Seleniranium Ions with Alkenes in the Gas Phase
Publisher: American Chemical Society (ACS)
Date: 27-01-2023
Photophysics and spectroscopy of 1,2-Benzazulene
Publisher: Elsevier BV
Date: 12-2021
Cooperative assemblies featuring hydrogen bonding and C H…π interactions in 2-(methanesulfonamido)benzohydrazide derivatives: Experimental, computational and biochemical assessment
Publisher: Elsevier BV
Date: 2024
Frontispiece: Guest‐induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes
Publisher: Wiley
Date: 05-07-2017
Synthesis, structure, and condensed-phase reactivity of [Ag3(μ3-H)(μ3-BH4)LPh3](BF4) (LPh = bis(diphenylphosphin
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8DT02437E
Abstract: Electrospray ionisation mass spectrometry (ESI-MS) was used to monitor the reaction of AgBF 4 , bis(diphenylphosphino)amine (dppa = (Ph 2 P) 2 NH = L Ph ) and NaBH 4 in acetonitrile.
Determinants of the efficiency of photon upconversion by triplet–triplet annihilation in the solid state: zinc porphyrin derivatives in PVA
Publisher: Royal Society of Chemistry (RSC)
Date: 2017
DOI: 10.1039/C7CP04746K
Abstract: Differences in efficiencies of photon upconversion are explained for a series of alkyl-substituted diphenyl and tetraphenyl zinc porphyrins.
Models for aerobic carbon monoxide dehydrogenase: synthesis, characterization and reactivity of paramagnetic MoVO(μ-S)CuI complexes
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C7SC04239F
Abstract: Complexes exhibiting the Mo V O(μ-S)Cu I cores, EPR properties, electronic structures and biomimetic reactions of aerobic Mo/Cu-containing carbon monoxide dehydrogenases are reported.
A novel paramagnetic coordination polymer, fabricated from Co(NCS)2 and 2-pyridinecarbaldehyde isonicotinoylhydrazone
Publisher: Elsevier BV
Date: 07-2021
Identification of Gibberellic Acid Derivatives That Deregulate Cholesterol Metabolism in Prostate Cancer Cells
Publisher: American Chemical Society (ACS)
Date: 23-02-2018
DOI: 10.1021/ACS.JNATPROD.7B00929
Abstract: The naturally occurring pentacyclic diterpenoid gibberellic acid (1) was used in the generation of a drug-like amide library using parallel-solution-phase synthesis. Prior to the synthesis, a virtual library was generated and prioritized based on drug-like physicochemical parameters such as log P, hydrogen bond donor/acceptor counts, and molecular weight. The structures of the synthesized analogues (2-13) were elucidated following analysis of the NMR, MS, UV, and IR data. Compound 12 afforded crystalline material, and its structure was confirmed by X-ray crystallographic analysis. All compounds were evaluated in vitro for cytotoxicity and deregulation of lipid metabolism in LNCaP prostate cancer cells. While no cytotoxic activity was identified at the concentrations tested, synthesized analogues 3, 5, 7, 10, and 11 substantially reduced cellular uptake of free cholesterol in prostate cancer cells, suggesting a novel role of gibberellic acid derivatives in deregulating cholesterol metabolism.
Modulating Carbon Dioxide Storage by Facile Synthesis of Nanoporous Pillared-Layered Metal–Organic Framework with Different Synthetic Routes
Publisher: American Chemical Society (ACS)
Date: 21-02-2022
DOI: 10.1021/ACS.INORGCHEM.1C03414
Abstract: A Zn(II)-based paddle wheel pillared-layered metal-organic framework, [Zn
Total Synthesis of the Putative Structure of Asperipin-2a and Stereochemical Reassignment
Publisher: American Chemical Society (ACS)
Date: 22-09-2020
Computational Study of the Donor–Acceptor Interactions Underlying the Variable Oxygen Probe
Publisher: American Chemical Society (ACS)
Date: 16-02-2021
A Ca-based nano bio-coordination polymer providing reversible structural conversion with ability to enhance cytotoxicity of curcumin and induce apoptosis in human gastric cancer AGS cells
Publisher: Royal Society of Chemistry (RSC)
Date: 2022
DOI: 10.1039/D2CE01258H
Abstract: A new bio-coordination polymer (bio-CP 2) was prepared, which indicated a reversible structural conversion in the presence and absence of water. This bio-CP showed positive effects on the water solubility and anticancer performances of curcumin.
Effects of the β‐heteroatom and leaving group on neighbouring group participation in the gas phase: A density functional theory study
Publisher: Wiley
Date: 03-10-2022
DOI: 10.1002/POC.4426
Abstract: Observation of the [M + H] + ion in electrospray ionisation mass spectrometry (ESI‐MS) for either product identification or further unimolecular reactivity studies is not always guaranteed. When a suitable donor is β to a good leaving group such as protonated alcohols, neighbouring group participation (NGP) is one process that can lead to facile in‐source decomposition leading to three‐membered ring product ions. In this study, lone pair rich heteroatoms are explored computationally as donors for the intramolecular displacement of either water or ammonia in protonated 2‐heteroethanols and ethanamines, respectively. Density functional theory (DFT) calculations showed that for the halogens (Cl, Br and I) both the loss of water and ammonia are overall endothermic processes with modest barriers for the 2‐haloethanol fragmentation by NGP. The chalcogens (S, Se and Te) displayed a significant shift with the loss of water becoming exothermic and the enthalpic barrier approximately zero in most cases leading to little [M + H] + ion observation. The loss of ammonia remained endothermic for both the chalcogens (S, Se and Te) and pnictogens (P, As and Sb), but the 2‐pnictoethanol fragmentation showed mixed results as two pathways were accessible due to the increased s character of the pnictogen lone pair. Examination of the donor–acceptor interactions by natural bond orbital (NBO) theory reflected an increase in the heteroatom lone pair participation at the transition state, but that stabilisation due to the polarisable CX bond dominated and should not be discounted in processes believed to proceed by nonvertical neighbouring group participation.
Copper(II) Complexes of 2,2′-Bisdipyrrins: Synthesis, Characterization, Cell Uptake, and Radiolabeling with Copper-64
Publisher: American Chemical Society (ACS)
Date: 08-08-2023
Concise synthesis of sulfoquinovose and sulfoquinovosyl diacylglycerides, and development of a fluorogenic substrate for sulfoquinovosidases
Publisher: Royal Society of Chemistry (RSC)
Date: 2020
DOI: 10.1039/C9OB02540E
Abstract: A new and efficient synthesis of sulfoquinovose [including ( 13 C 6 )-SQ] and of saturated and unsaturated sulfoquinovosyl diacylglycerol derivatives, and development of a fluorogenic glycoside useful for kinetic investigations on sulfoquinovosidases.
Application of the Variable Oxygen Probe to Derivatives of 2,6-Dimethyltetrahydropyran-4-ol: Evidence for Through-Bond nO–σCC–σ*CO Interactions
Publisher: CSIRO Publishing
Date: 2021
DOI: 10.1071/CH20149
Abstract: The variable oxygen probe has been applied to axial and equatorial 4-pyranols 4 and 5 and their ester and ether derivatives. Plots of C–OR bond distance versus pKa (ROH) provided evidence for slightly stronger donation into the σ*C–OR antibonding orbital in the equatorial derivatives 5 than in the axial derivatives 4, which is consistent with the presence of a through-bond nO–σCC–σ*CO interaction in 5. Evidence in support of this interpretation was also provided by density functional theory (DFT) calculations and natural bond orbital (NBO) analyses of the various orbital interactions in the 4-pyranols 4 and 5, their protonated analogues 4·H2O+ and 5·H2O+, and the corresponding cyclohexane derivatives 6, 7, 6·H2O+, and 7·H2O+.
The performance of conjugated polymers as emitters for triplet–triplet annihilation upconversion
Publisher: Royal Society of Chemistry (RSC)
Date: 2021
DOI: 10.1039/D1MA00068C
Abstract: Phenylene–ethynylene–anthracene copolymer was used as the emitter in triplet–triplet annihilation upconversion outperforming well-known poly(phenylene–vinylene)s.
Oxorhenium(V) and Oxotechnetium(V) Complexes of N3S Tetradentate Ligands with a Styrylpyridyl Functional Group: Toward Imaging Agents to Assist in the Diagnosis of Alzheimer’s Disease
Publisher: American Chemical Society (ACS)
Date: 23-08-2021
Copper Bis(thiosemicarbazonato)-stilbenyl Complexes That Bind to Amyloid-β Plaques
Publisher: American Chemical Society (ACS)
Date: 28-07-2020
Mixed annihilation electrogenerated chemiluminescence of iridium(iii ) complexes
Publisher: Royal Society of Chemistry (RSC)
Date: 2018
DOI: 10.1039/C8CP01737A
Abstract: The annihilation electrogenerated chemiluminescence of mixtures of Ir( iii ) complexes is eliminated by manipulating reduction potentials through subtle changes in ligand structure.
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