ARC Future Fellowships - Grant ID: FT190100544

Funding Activity

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Funded Activity Summary

Hidden complexity in microRNA function. This project aims to determine the extent to which microRNAs function through “non-canonical” mechanisms within cell nuclei, how their roles are expanded by naturally occurring sequence variation and how their activity is controlled by little known families of genes that sequester and inhibit their availability. The knowledge generated is significant as microRNAs regulate the expression of virtually all genes and biological processes, yet these mechanisms of function remain poorly characterised and seldom considered. The expected outcome of better understanding mechanisms through which microRNAs work should provide significant benefit to safe and effective development of microRNAs for future agricultural or therapeutic application.

Funded Activity Details

Start Date: 01-2020

End Date: 01-2024

Funding Scheme: ARC Future Fellowships

Funding Amount: $876,038.00

Funder: Australian Research Council