Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP220101819
Funding Status
Active
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Funded Activity Summary
The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling for a synergistic defence to adapt to the nanoparticle toxicity. The pioneering knowledge is the foundation for technologies targeting the interspecies metabolite cross-talking to overcome the resistance phenomena, ensuring a long-term efficacy of the alternative antimicrobial on the difficult-to-control pathogenic growth.Funded Activity Details
Start Date: 09-2022
End Date: 09-2025
Funding Scheme: Discovery Projects
Funding Amount: $375,000.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Nanotechnology | Environmental Nanotechnology | Nanotoxicology, Health and Safety |
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in Engineering | Environmental Health | Health Protection and/or Disaster Response
