Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP220103543
Funding Status
Active
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Funded Activity Summary
Nanoengineering of Biomaterial Surfaces to Tailor Innate Immune Responses. The overarching aim of this project is to provide a mechanistic understanding of how surface nanotopography affects inflammatory responses. Recently, we showed that surface nanotopography induced conformational changes in adsorbed proteins can activate or deactivate immune cells. These exciting findings are important because they show that it may be possible to engineer the nanotopography of a biomedical device surface in a manner which leads to a desired and predictable level of inflammation. The outcomes of the project will create new fundamental knowledge that in the future can instruct the development of the next generation of biomaterials capable of controlling and directing the body’s inflammatory responses.Funded Activity Details
Start Date: 07-2022
End Date: 06-2025
Funding Scheme: Discovery Projects
Funding Amount: $529,846.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Functional Materials | Biomaterials | Biomedical Engineering | Innate Immunity
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Physical Sciences | Expanding Knowledge in Engineering | Expanding Knowledge in the Biological Sciences |
