ARC Future Fellowships - Grant ID: FT160100366

Funding Activity

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Funded Activity Summary

The mechanochemical basis of cell polarity. This project aims to study how epithelial cells initiate polarisation, a major question in biology that conventional biochemical, cell biological and genetic approaches have not answered. This project will investigate the mechanochemical basis of symmetry breaking in the cellular cortex, a thin layer of actomyosin filaments underneath the plasma membrane, and how this forms signalling zones. Understanding polarity is expected to improve epithelia manipulation in disciplines from tissue engineering to regenerative biology and reveal how epithelial architecture and physiology are generated.

Funded Activity Details

Start Date: 2017

End Date: 12-2020

Funding Scheme: ARC Future Fellowships

Funding Amount: $680,524.00

Funder: Australian Research Council