Website
http://dataportal.arc.gov.au/NCGP/API/grants/DP150104212
Funding Status
Closed
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Funded Activity Summary
Surface Engineered Biomaterials to Control Inflammation. The overarching aim of this project is to provide a mechanistic understanding of how surface nanotopography affects inflammatory responses. Experimental evidence demonstrates that engineered surface nanotopography in combination with surface chemistry downregulates the expression of proinflammatory cytokines from primary macrophages. The significance of these findings is that it may be possible to engineer the nanotopography of a biomedical device surface in a manner which leads to a desired and predictable level of inflammation and subsequent foreign body reaction (FBR) medical implants and tissue engineering constructs.Funded Activity Details
Start Date: 01-2015
End Date: 12-2020
Funding Scheme: Discovery Projects
Funding Amount: $329,900.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Medical Devices | Biomaterials | Biomedical Engineering | Innate Immunity
ANZSRC Socio-Economic Objective (SEO)
Expanding Knowledge in the Physical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |
