Website
http://dataportal.arc.gov.au/NCGP/API/grants/DE140100162
Funding Status
Closed
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Funded Activity Summary
Enzymatic synthesis of pro-resolution lipid mediators: Towards new therapeutic strategies for inflammatory diseases. Inflammation is a major contributing factor in many diseases, including arthritis, Alzheimer's disease, multiple sclerosis, cardiovascular disease and cancer. It has recently been shown that the resolution of inflammation is an active biological process initiated by lipid mediators. The aim of this project is to synthesise and characterise pro-resolution lipid mediators, elucidate the enzyme cascades involved in their biosynthesis and explore their roles in the active resolution of inflammation. This project will provide a fundamental understanding of pro-resolution and anti-inflammatory pathways as well as new therapeutic target molecules for the treatment of inflammatory diseases.Funded Activity Details
Start Date: 2014
End Date: 11-2019
Funding Scheme: Discovery Early Career Researcher Award
Funding Amount: $374,005.00
Funder: Australian Research Council
Research Topics
ANZSRC Field of Research (FoR)
Biocatalysis and Enzyme Technology | Medicinal and Biomolecular Chemistry | Separation Science | Biologically Active Molecules
